Zhenshan Jia, PhD

Research Assistant Professor

  • 403 Citations
  • 11 h-Index
20032018
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Research Output 2003 2018

  • 403 Citations
  • 11 h-Index
  • 23 Article
  • 1 Chapter
2018
1 Citation (Scopus)

Bone-targeting liposome formulation of Salvianic acid A accelerates the healing of delayed fracture Union in Mice

Liu, Y., Jia, Z., Akhter, M. P., Gao, X., Wang, X., Wang, X., Zhao, G., Wei, X., Zhou, Y., Wang, X., Hartman, C. W., Fehringer, E. V., Cui, L. & Wang, D., Oct 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 7, p. 2271-2282 12 p.

Research output: Contribution to journalArticle

Fracture Healing
Liposomes
Bone
Bone and Bones
Acids
1 Citation (Scopus)

Local Application of Pyrophosphorylated Simvastatin Prevents Experimental Periodontitis

Wang, X., Jia, Z., Almoshari, Y., Lele, S. M., Reinhardt, R. A. & Wang, D., Aug 1 2018, In : Pharmaceutical Research. 35, 8, 164.

Research output: Contribution to journalArticle

Simvastatin
Periodontitis
Solubility
Bone
Water
2 Citations (Scopus)

Micelle-forming dexamethasone prodrug attenuates nephritis in lupus-prone mice without apparent glucocorticoid side effects

Jia, Z., Wang, X., Wei, X., Zhao, G., Foster, K. W., Qiu, F., Gao, Y., Yuan, F., Yu, F., Thiele, G. M., Bronich, T. K., O'Dell, J. R. & Wang, D., Aug 28 2018, In : ACS Nano. 12, 8, p. 7663-7681 19 p.

Research output: Contribution to journalArticle

nephritis
glucocorticoids
Prodrugs
Micelles
Dexamethasone
2017
3 Citations (Scopus)

Standardized rat model testing effects of inflammation and grafting on extraction healing

Willett, E. S., Liu, J., Berke, M., Giannini, P. J., Schmid, M., Jia, Z., Wang, X., Wang, X., Samson, K., Yu, F., Wang, D., Nawshad, A. & Reinhardt, R. A., Aug 2017, In : Journal of periodontology. 88, 8, p. 799-807 9 p.

Research output: Contribution to journalArticle

Bone Matrix
Simvastatin
Inflammation
Alveolar Process
Osteitis
2016
11 Citations (Scopus)

Effect of simvastatin prodrug on experimental periodontitis

Bradley, A. D., Zhang, Y., Jia, Z., Zhao, G., Wang, X., Pranke, L., Schmid, M. J., Wang, D. & Reinhardt, R. A., May 2016, In : Journal of periodontology. 87, 5, p. 577-582 6 p.

Research output: Contribution to journalArticle

Simvastatin
Periodontitis
Prodrugs
Ligation
Osteitis
7 Citations (Scopus)

The Evaluation of Therapeutic Efficacy and Safety Profile of Simvastatin Prodrug Micelles in a Closed Fracture Mouse Model

Zhang, Y., Jia, Z., Yuan, H., Dusad, A., Ren, K., Wei, X., Fehringer, E. V., Purdue, P. E., Daluiski, A., Goldring, S. R. & Wang, D., Aug 1 2016, In : Pharmaceutical Research. 33, 8, p. 1959-1971 13 p.

Research output: Contribution to journalArticle

Closed Fractures
Simvastatin
Prodrugs
Micelles
Femoral Fractures
2015
19 Citations (Scopus)

Simvastatin prodrug micelles target fracture and improve healing

Jia, Z., Zhang, Y., Chen, Y. H., Dusad, A., Yuan, H., Ren, K., Li, F., Fehringer, E. V., Purdue, P. E., Goldring, S. R., Daluiski, A. & Wang, D., Feb 28 2015, In : Journal of Controlled Release. 200, p. 23-34 12 p.

Research output: Contribution to journalArticle

Fracture Healing
Simvastatin
Prodrugs
Micelles
Bone Fractures
2014
8 Citations (Scopus)
Fullerenes
Epoxy Compounds
Single crystals
X rays
fullerene C60
3 Citations (Scopus)

The development of drug-free therapy for prevention of dental caries

Chen, F., Jia, Z., Rice, K. C., Reinhardt, R. A., Bayles, K. W. & Wang, D., Nov 2014, In : Pharmaceutical Research. 31, 11, p. 3031-3037 7 p.

Research output: Contribution to journalArticle

Artificial Teeth
Dental Caries
Copolymers
Drug Therapy
Adhesion
2013
2 Citations (Scopus)

Biomedical Applications of "Click"-Modified Cyclodextrins

Jia, Z., Singh, R. K. & Wang, D., Feb 6 2013, Click Chemistry in Glycoscience: New Developments and Strategies. John Wiley and Sons, p. 271-292 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cyclodextrins
Cycloaddition
Cycloaddition Reaction
Click Chemistry
Alkynes
12 Citations (Scopus)

The development of dentotropic micelles with biodegradable tooth-binding moieties

Chen, F., Jia, Z., Rice, K. C., Reinhardt, R. A., Bayles, K. W. & Wang, D., Nov 1 2013, In : Pharmaceutical Research. 30, 11, p. 2808-2817 10 p.

Research output: Contribution to journalArticle

Micelles
Tooth
Durapatite
Saliva
Triclosan
2011
24 Citations (Scopus)

Biscinchona alkaloids as highly efficient bifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroalkenes at ambient temperature

Li, F., Li, Y. Z., Jia, Z. S., Xu, M. H., Tian, P. & Lin, G. Q., Dec 30 2011, In : Tetrahedron. 67, 52, p. 10186-10194 9 p.

Research output: Contribution to journalArticle

Malonates
Alkaloids
Catalysts
Temperature
Enantioselectivity
9 Citations (Scopus)

Preparation of a 12-membered open-cage fullerendione through silane/borane-promoted formation of ketal moieties and oxidation of a vicinal fullerendiol

Zhang, G., Zhang, Q., Jia, Z., Liang, S., Gan, L. & Li, Y., Aug 19 2011, In : Journal of Organic Chemistry. 76, 16, p. 6743-6748 6 p.

Research output: Contribution to journalArticle

Boranes
Fullerenes
Silanes
Oxidation
Peroxides
2010
14 Citations (Scopus)

Carving two adjacent holes on [60]fullerene through two consecutive epoxide to diol to dione transformations

Xiao, Z., Yao, J., Yu, Y., Jia, Z. & Gan, L., Nov 28 2010, In : Chemical Communications. 46, 44, p. 8365-8367 3 p.

Research output: Contribution to journalArticle

Epoxy Compounds
Fullerenes
Orifices
Oxidation
Acids
53 Citations (Scopus)

One-pot synthesis of chiral α-methylene-γ-lactams with excellent diastereoselectivities and enantioselectivities

Shen, A., Liu, M., Jia, Z. S., Xu, M. H. & Lin, G. Q., Nov 19 2010, In : Organic Letters. 12, 22, p. 5154-5157 4 p.

Research output: Contribution to journalArticle

Lactams
Enantioselectivity
methylene
isomers
synthesis
2009
35 Citations (Scopus)

Efficient cage-opening cascade process for the preparation of water-encapsulated [60]fullerene derivatives

Zhang, Q., Jia, Z., Liu, S., Zhang, G., Xiao, Z., Yang, D., Gan, L., Wang, Z. & Li, Y., Jul 2 2009, In : Organic Letters. 11, 13, p. 2772-2774 3 p.

Research output: Contribution to journalArticle

Fullerenes
orifices
Orifices
fullerenes
cascades
2008
23 Citations (Scopus)

Reactivity of fullerene epoxide: Preparation of fullerene-fused thiirane, tetrahydrothiazolidin-2-one, and 1,3-dioxolane

Yang, X., Huang, S., Jia, Z., Xiao, Z., Jiang, Z., Zhang, Q., Gan, L., Zheng, B., Yuan, G. & Zhang, S., Apr 4 2008, In : Journal of Organic Chemistry. 73, 7, p. 2518-2526 9 p.

Research output: Contribution to journalArticle

Fullerenes
Epoxy Compounds
Derivatives
Isocyanates
Aluminum Oxide
2007
24 Citations (Scopus)

Amination of [60]fullerene by ammonia and by primary and secondary aliphatic amines - Preparation of amino[60]fullerene peroxides

Hu, X., Jiang, Z., Jia, Z., Huang, S., Yang, X., Li, Y., Gan, L., Zhang, S. & Zhu, D., Feb 6 2007, In : Chemistry - A European Journal. 13, 4, p. 1129-1141 13 p.

Research output: Contribution to journalArticle

Amination
Peroxides
Fullerenes
Ammonia
Amines
11 Citations (Scopus)

Boomerang-type substitution reaction: Reactivity of fullerene epoxides and a halofullerenol

Jia, Z., Zhang, X., Zhang, G., Huang, S., Fang, H., Hu, X., Li, Y., Gan, L., Zhang, S. & Zhu, D., Jul 2 2007, In : Chemistry - An Asian Journal. 2, 2, p. 290-300 11 p.

Research output: Contribution to journalArticle

Chlorohydrins
Fullerenes
Epoxy Compounds
Isomers
Spectrum Analysis
8 Citations (Scopus)

Efficient conversion of bromofullerene to alkoxyfullerenes through either homolytic or heterolytic cleavage of C60-Br bond

Jia, Z., Zhang, Q., Li, Y., Gan, L., Zheng, B., Yuan, G., Zhang, S. & Zhu, D., Sep 10 2007, In : Tetrahedron. 63, 37, p. 9120-9123 4 p.

Research output: Contribution to journalArticle

Fullerenes
Bromine
Photolysis
Peroxides
Silver
22 Citations (Scopus)

From fullerene-mixed peroxide to open-cage oxafulleroid C 59(O)3(OH)2(OOtBu)2 embedded with furan and lactone motifs

Wang, F., Xiao, Z., Gan, L., Jia, Z., Jiang, Z., Zhang, S., Zheng, B. & Gu, Y., Apr 26 2007, In : Organic Letters. 9, 9, p. 1741-1743 3 p.

Research output: Contribution to journalArticle

Fullerenes
furans
Peroxides
peroxides
Lactones
86 Citations (Scopus)

Synthesis of [59]fullerenones through peroxide-mediated stepwise cleavage of fullerene skeleton bonds and X-ray structures of their water-encapsulated open-cage complexes

Xiao, Z., Yao, J., Yang, D., Wang, F., Huang, S., Gan, L., Jia, Z., Jiang, Z., Yang, X., Zheng, B., Yuan, G., Zhang, S. & Wang, Z., Dec 26 2007, In : Journal of the American Chemical Society. 129, 51, p. 16149-16162 14 p.

Research output: Contribution to journalArticle

Fullerenes
Peroxides
Skeleton
X-Rays
X rays
2006
24 Citations (Scopus)

Lewis acid promoted preparation of isomerically pure fullerenols from fullerene peroxides C60(OOt-Bu)6 and C60(O) (OOt-Bu)6

Wang, F., Xiao, Z., Yao, Z., Jia, Z., Huang, S., Gan, L., Zhou, J., Yuan, G. & Zhang, S., Jun 9 2006, In : Journal of Organic Chemistry. 71, 12, p. 4374-4382 9 p.

Research output: Contribution to journalArticle

Fullerenes
Lewis Acids
Peroxides
Bromides
fullerenol
2003
1 Citation (Scopus)

Trans-Dichlorobis{2-[2-(4-methoxyphenyl)ethenyl]-5-methyl-1, 3-benzoxazole-κN}cobalt(II)

Jia, Z. S., Liu, H. M., Zheng, Y. & Zhang, W. Q., Nov 1 2003, In : Acta Crystallographica Section E: Structure Reports Online. 59, 11, p. m1002-m1003

Research output: Contribution to journalArticle

Benzoxazoles
Cobalt
cobalt
Ligands
ligands