Yazen Alnouti, PhD

Associate Professor

  • 2036 Citations
  • 25 h-Index
20022020
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  • 3 Similar Profiles
Bile Acids and Salts Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences
Prodrugs Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Metabolites Chemical Compounds
Liver Chemical Compounds
Tissue Chemical Compounds
Rats Chemical Compounds

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Projects 2009 2020

Pharmacokinetics
Pharmaceutical Preparations
efavirenz
Macaca mulatta
Rodentia

Research Output 2002 2020

  • 2036 Citations
  • 25 h-Index
  • 67 Article
  • 4 Review article
  • 1 Paper

Direct and indirect quantification of phosphate metabolites of nucleoside analogs in biological samples

Gautam, N., Alamoudi, J. A., Kumar, S. & Alnouti, Y., Jan 30 2020, In : Journal of Pharmaceutical and Biomedical Analysis. 178, 112902.

Research output: Contribution to journalReview article

Metabolites
Nucleosides
Nucleotides
Phosphates
Reverse Transcriptase Inhibitors

A long acting nanoformulated lamivudine ProTide

Smith, N., Bade, A. N., Soni, D., Gautam, N., Alnouti, Y., Herskovitz, J., Ibrahim, I. M., Wojtkiewicz, M. S., Dyavar Shetty, B. L., McMillan, J. E., Gendelman, H. E. & Edagwa, B., Dec 2019, In : Biomaterials. 223, 119476.

Research output: Contribution to journalArticle

Pharmacokinetics
Lamivudine
Macrophages
T-cells
Metabolites

Assessing the lymphoid tissue bioavailability of antiretrovirals in human primary lymphoid endothelial cells and in mice

Dyavar, S. R., Gautam, N., Podany, A. T., Winchester, L. C., Weinhold, J. A., Mykris, T. M., Campbell, K. M., Alnouti, Y. & Fletcher, C. V., Oct 1 2019, In : The Journal of antimicrobial chemotherapy. 74, 10, p. 2974-2978 5 p.

Research output: Contribution to journalArticle

efavirenz
Lymphoid Tissue
Biological Availability
Endothelial Cells
Lymphocytes

Creation of a long-acting rilpivirine prodrug nanoformulation

Hilaire, J. R., Bade, A. N., Sillman, B., Gautam, N., Herskovitz, J., Dyavar Shetty, B. L., Wojtkiewicz, M. S., Szlachetka, A., Lamberty, B. G., Sravanam, S., Fox, H. S., Alnouti, Y., Dash, P. K., McMillan, J. E. M., Edagwa, B. J. & Gendelman, H. E., Oct 2019, In : Journal of Controlled Release. 311-312, p. 201-211 11 p.

Research output: Contribution to journalArticle

Rilpivirine
Prodrugs
Pharmaceutical Preparations
Half-Life
Therapeutics

Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators

Sharma, S., Kozek, K. A., Abney, K. K., Kumar, S., Gautam, N., Alnouti, Y., David Weaver, C. & Hopkins, C. R., Mar 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 6, p. 791-796 6 p.

Research output: Contribution to journalArticle

G Protein-Coupled Inwardly-Rectifying Potassium Channels
Acetamides
Inwardly Rectifying Potassium Channel
Potassium Channels
GTP-Binding Proteins