Yazen Alnouti, PhD

Associate Professor

  • 2019 Citations
  • 25 h-Index
20022020
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Fingerprint Dive into the research topics where Yazen Alnouti is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Bile Acids and Salts Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences
Liver Chemical Compounds
Pharmaceutical Preparations Medicine & Life Sciences
Prodrugs Medicine & Life Sciences
Metabolites Chemical Compounds
Tissue Chemical Compounds
Rats Chemical Compounds

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Projects 2009 2020

Pharmacokinetics
Pharmaceutical Preparations
efavirenz
Macaca mulatta
Rodentia

Research Output 2002 2019

  • 2019 Citations
  • 25 h-Index
  • 64 Article
  • 3 Review article
  • 1 Paper

Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators

Sharma, S., Kozek, K. A., Abney, K. K., Kumar, S., Gautam, N., Alnouti, Y., David Weaver, C. & Hopkins, C. R., Mar 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 6, p. 791-796 6 p.

Research output: Contribution to journalArticle

G Protein-Coupled Inwardly-Rectifying Potassium Channels
Acetamides
Inwardly Rectifying Potassium Channel
Potassium Channels
GTP-Binding Proteins
2 Citations (Scopus)

Pharmacokinetic testing of a first-generation cabotegravir prodrug in rhesus macaques

McMillan, J. M., Szlachetka, A., Zhou, T., Morsey, B., Lamberty, B., Callen, S., Gautam, N., Alnouti, Y., Edagwa, B. J., Gendelman, H. E. & Fox, H. S., Mar 1 2019, In : AIDS (London, England). 33, 3, p. 585-588 4 p.

Research output: Contribution to journalArticle

Prodrugs
Macaca mulatta
Pharmacokinetics
Poloxamer
HIV Infections

Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation

Ibrahim, I. M., Bade, A. N., Lin, Z., Soni, D., Wojtkiewicz, M., Shetty, B. L. D., Gautam, N., McMillan, J. M., Alnouti, Y., Edagwa, B. J. & Gendelman, H. E., Jan 1 2019, In : International journal of nanomedicine. 14, p. 6231-6247 17 p.

Research output: Contribution to journalArticle

Open Access
Pharmacokinetics
Prodrugs
Nanocrystals
Macrophages
Esterification

Synthesis of a long acting nanoformulated emtricitabine ProTide

Soni, D., Bade, A. N., Gautam, N., Herskovitz, J., Ibrahim, I. M., Smith, N., Wojtkiewicz, M. S., Dyavar Shetty, B. L., Alnouti, Y., McMillan, J. M., Gendelman, H. E. & Edagwa, B. J., Nov 1 2019, In : Biomaterials. 222, 119441.

Research output: Contribution to journalArticle

Macrophages
Prodrugs
T-cells
Viruses
Pharmaceutical Preparations
23 Citations (Scopus)

Creation of a long-acting nanoformulated dolutegravir

Sillman, B., Bade, A. N., Dash, P. K., Bhargavan, B., Kocher, T., Mathews, S., Su, H., Kanmogne, G. D., Poluektova, L. Y., Gorantla, S., McMillan, J. M., Gautam, N., Alnouti, Y., Edagwa, B. J. & Gendelman, H. E., Dec 1 2018, In : Nature Communications. 9, 1, 443.

Research output: Contribution to journalArticle

human immunodeficiency virus
drugs
mice
macrophages
viruses