Yazen Alnouti, PhD

Associate Professor

  • 1695 Citations
  • 25 h-Index
20022020
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Metabolites Chemical Compounds
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Plasmas Chemical Compounds

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Projects 2009 2020

Pharmacokinetics
Pharmaceutical Preparations
efavirenz
Macaca mulatta
Rodentia

Research Output 2002 2018

  • 1695 Citations
  • 25 h-Index
  • 62 Article
  • 1 Conference contribution
  • 1 Review article
6 Citations

Creation of a long-acting nanoformulated dolutegravir

Sillman, B., Bade, A. N., Dash, P. K., Bhargavan, B., Kocher, T., Mathews, S., Su, H., Kanmogne, G. D., Poluektova, L. Y., Gorantla, S., McMillan, J., Gautam, N., Alnouti, Y., Edagwa, B. & Gendelman, H. E., Dec 1 2018, In : Nature Communications. 9, 1, 443.

Research output: Contribution to journalArticle

human immunodeficiency virus
drugs
mice
macrophages
viruses
8 Citations

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles

Zhou, T., Su, H., Dash, P., Lin, Z., Dyavar Shetty, B. L., Kocher, T., Szlachetka, A., Lamberty, B., Fox, H. S., Poluektova, L., Gorantla, S., McMillan, J. E., Gautam, N., Mosley, R. L., Alnouti, Y., Edagwa, B. & Gendelman, H. E., Jan 1 2018, In : Biomaterials. 151, p. 53-65 13 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Lymphocytes
Macrophages
Body fluids
Prodrugs
8 Citations

Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

Hartmann, P., Hochrath, K., Horvath, A., Chen, P., Seebauer, C. T., Llorente, C., Wang, L., Alnouti, Y., Fouts, D. E., Stärkel, P., Loomba, R., Coulter, S., Liddle, C., Yu, R. T., Ling, L., Rossi, S. J., Depaoli, A. M., Downes, M., Evans, R. M., Brenner, D. A. & 1 othersSchnabl, B., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Alcoholic Liver Diseases
Bile Acids and Salts
Ethanol
Liver
3 Citations

Optimizing the preparation and stability of decorated antiretroviral drug nanocrystals

Zhou, T., Lin, Z., Puligujja, P., Palandri, DI., Hilaire, J., Araínga, M., Smith, N., Gautam, N., McMillan, J., Alnouti, Y., Liu, X., Edagwa, B. & Gendelman, H. E., Apr 1 2018, In : Nanomedicine. 13, 8, p. 871-885 15 p.

Research output: Contribution to journalArticle

Folic Acid
Nanoparticles
Nanocrystals
manufacturing
drug
2 Citations

Pharmacokinetics of a long-acting nanoformulated dolutegravir prodrug in rhesus macaques

McMillan, J. E., Szlachetka, A., Slack, L., Sillman, B., Lamberty, B., Morsey, B., Callen, S., Gautam, N., Alnouti, Y., Edagwa, B., Gendelman, H. E. & Fox, H. S., Jan 1 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, e01316-17.

Research output: Contribution to journalArticle

Prodrugs
Macaca mulatta
Pharmacokinetics
Intramuscular Injections
Half-Life