Yazen Alnouti, PhD

Associate Professor

  • 1872 Citations
  • 25 h-Index
20022020
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 1 Similar Profiles
Bile Acids and Salts Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences
Liver Chemical Compounds
Pharmaceutical Preparations Medicine & Life Sciences
Metabolites Chemical Compounds
Tissue Chemical Compounds
Rats Chemical Compounds
Plasmas Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2020

Pharmacokinetics
Pharmaceutical Preparations
efavirenz
Macaca mulatta
Rodentia

Research Output 2002 2019

  • 1872 Citations
  • 25 h-Index
  • 64 Article
  • 1 Conference contribution
  • 1 Review article

Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators

Sharma, S., Kozek, K. A., Abney, K. K., Kumar, S., Gautam, N., Alnouti, Y., David Weaver, C. & Hopkins, C. R., Mar 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 6, p. 791-796 6 p.

Research output: Contribution to journalArticle

G Protein-Coupled Inwardly-Rectifying Potassium Channels
Acetamides
Inwardly Rectifying Potassium Channel
Potassium Channels
GTP-Binding Proteins

Pharmacokinetic testing of a first-generation cabotegravir prodrug in rhesus macaques

McMillan, J. E., Szlachetka, A., Zhou, T., Morsey, B., Lamberty, B., Callen, S., Gautam, N., Alnouti, Y., Edagwa, B. J., Gendelman, H. E. & Fox, H. S., Mar 1 2019, In : AIDS (London, England). 33, 3, p. 585-588 4 p.

Research output: Contribution to journalArticle

Prodrugs
Macaca mulatta
Pharmacokinetics
Poloxamer
HIV Infections
13 Citations (Scopus)

Creation of a long-acting nanoformulated dolutegravir

Sillman, B., Bade, A. N., Dash, P. K., Bhargavan, B., Kocher, T., Mathews, S., Su, H., Kanmogne, G. D., Poluektova, L. Y., Gorantla, S., McMillan, J. M., Gautam, N., Alnouti, Y., Edagwa, B. J. & Gendelman, H. E., Dec 1 2018, In : Nature Communications. 9, 1, 443.

Research output: Contribution to journalArticle

human immunodeficiency virus
drugs
mice
macrophages
viruses
12 Citations (Scopus)

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles

Zhou, T., Su, H., Dash, P., Lin, Z., Dyavar Shetty, B. L., Kocher, T., Szlachetka, A., Lamberty, B., Fox, H. S., Poluektova, L. Y., Gorantla, S., McMillan, J. M., Gautam, N., Mosley, R. L., Alnouti, Y., Edagwa, B. J. & Gendelman, H. E., Jan 1 2018, In : Biomaterials. 151, p. 53-65 13 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Lymphocytes
Macrophages
Body fluids
Prodrugs
16 Citations (Scopus)

Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

Hartmann, P., Hochrath, K., Horvath, A., Chen, P., Seebauer, C. T., Llorente, C., Wang, L., Alnouti, Y., Fouts, D. E., Stärkel, P., Loomba, R., Coulter, S., Liddle, C., Yu, R. T., Ling, L., Rossi, S. J., Depaoli, A. M., Downes, M., Evans, R. M., Brenner, D. A. & 1 othersSchnabl, B., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Alcoholic Liver Diseases
Bile Acids and Salts
Ethanol
Liver