• 8196 Citations
  • 23 h-Index
19942019
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Fingerprint Dive into the research topics where Xu Luo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Apoptosis Medicine & Life Sciences
Proteins Medicine & Life Sciences
Mitochondria Medicine & Life Sciences
Upstream Stimulatory Factors Medicine & Life Sciences
Mitochondrial Membranes Medicine & Life Sciences
Noxae Medicine & Life Sciences
Cytochromes c Medicine & Life Sciences
Caspase 8 Medicine & Life Sciences

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Projects 2003 2013

Mechanisms of Bax Activation

Luo, X.

National Institutes of Health

2/1/061/31/12

Project: Research project

Apoptosis
Molecular Biology
Mitochondria
bcl-2 Homologous Antagonist-Killer Protein
bcl-2-Associated X Protein

Nebraska Center for Cellular Signaling

Johnson, K. R., Simpson, M. A., Wahl, J. K., Caplan, S. H., Nawshad, A., Luo, X., Oakley, G. G., Furukawa, M., Wang, J., Lewis, R. E., Caplan, S. H., Naslavsky, N., Dong, J., Opavsky, R., Wahl, J. K., Solheim, J. C., Peng, A., Luo, X., Simpson, M. A., Wheelock, M., Koka, S., Dey, B., Hansen, L., Gladyshev, V. N., Nawaz, Z., Yaping, T., Wang, Z., Premaraj, S., Taylor, G. S., Tsai, M. & Mehta, P. P.

National Institutes of Health

9/19/036/30/13

Project: Research project

funding
school
infrastructure
grant
dentistry

Research Output 1994 2019

  • 8196 Citations
  • 23 h-Index
  • 33 Article
  • 1 Review article
3 Citations (Scopus)

BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL

Greaves, G., Milani, M., Butterworth, M., Carter, R. J., Byrne, D. P., Eyers, P. A., Luo, X., Cohen, G. M. & Varadarajan, S., Jun 1 2019, In : Cell Death and Differentiation. 26, 6, p. 1037-1047 11 p.

Research output: Contribution to journalArticle

Pharmacology
Apoptosis
Proteins
Cell Line
Neoplasms

CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax

Kour, S., Rana, S., Contreras, J. I., King, H. M., Robb, C. M., Sonawane, Y. A., Bendjennat, M., Crawford, A. J., Barger, C. J., Kizhake, S., Luo, X., Hollingsworth, M. A. & Natarajan, A., Oct 1 2019, In : Molecular pharmacology. 96, 4, p. 419-429 11 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
Down-Regulation
Cell Line
Apoptosis
Clustered Regularly Interspaced Short Palindromic Repeats

DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis

Milani, M., Beckett, A. J., Al-Zebeeby, A., Luo, X., Prior, I. A., Cohen, G. M. & Varadarajan, S., Dec 1 2019, In : Cell Death Discovery. 5, 1, 117.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Dynamics
Apoptosis
Cytochromes c
Proteins
Mitochondrial Membranes
1 Citation (Scopus)

Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane

Farmer, T., O'Neill, K. L., Naslavsky, N., Luo, X. & Caplan, S. H., Jan 1 2019, In : Molecular biology of the cell. 30, 10, p. 1138-1146 9 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Membranes
Cell Survival
Apoptosis
Endosomes
Proteins

SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p

Wu, W., He, K., Guo, Q., Chen, J., Zhang, M., Huang, K., Yang, D., Wu, L., Deng, Y., Luo, X., Yu, H., Ding, Q. & Xiang, G., May 1 2019, In : Journal of cellular and molecular medicine. 23, 5, p. 3118-3129 12 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Colorectal Neoplasms
Proteins
Energy Metabolism
Apoptosis