Wasim Nasser, PhD

Assistant Professor

  • 2058 Citations
  • 19 h-Index
20052020
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2005 2020

Filter
Article
2020

A phase I study of weekly doxorubicin and oral topotecan for patients with relapsed or refractory small cell lung cancer (SCLC): A Fred and Pamela Buffet Cancer Center Clinical Trials Network study

Ernani, V., Jahan, R., Smith, L. M., Marr, A. S., Kimbrough, S. E., Kos, M. E., Tijerina, J., Pivovar, S., Lakshmanan, I., Ketcham, M., Rauth, S., Mallya, K., Nasser, M. W., Jain, M., Kessinger, A., Batra, S. K. & Ganti, A. K., 2020, In : Cancer Treatment and Research Communications. 22, 100162.

Research output: Contribution to journalArticle

Open Access
Topotecan
Small Cell Lung Carcinoma
Doxorubicin
Clinical Trials
Neoplasms
2018
19 Citations (Scopus)

Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation

Ahirwar, D. K., Nasser, M. W., Ouseph, M. M., Elbaz, M., Cuitiño, M. C., Kladney, R. D., Varikuti, S., Kaul, K., Satoskar, A. R., Ramaswamy, B., Zhang, X., Ostrowski, M. C., Leone, G. & Ganju, R. K., Aug 9 2018, In : Oncogene. 37, 32, p. 4428-4442 15 p.

Research output: Contribution to journalArticle

Fibroblasts
Breast Neoplasms
Neoplasm Metastasis
Blood Vessels
Endothelial Cells
18 Citations (Scopus)

Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma

Kanteti, R., Mirzapoiazova, T., Riehm, J. J., Dhanasingh, I., Mambetsariev, B., Wang, J., Kulkarni, P., Kaushik, G., Seshacharyulu, P., Palanimuthu Ponnusamy, M., Kindler, H. L., Nasser, M. W., Batra, S. K. & Salgia, R., Apr 3 2018, In : Cancer Biology and Therapy. 19, 4, p. 316-327 12 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Pancreatic Neoplasms
Organoids
Adenocarcinoma
Cell Line
2 Citations (Scopus)

Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma

Wang, J., Mirzapoiazova, T., Carol Tan, Y. H., Pang, K. M., Pozhitkov, A., Wang, Y., Wang, Y., Mambetsariev, B., Wang, E., Nasser, M. W., Batra, S. K., Raz, D., Reckamp, K., Kulkarni, P., Zheng, Y. & Salgia, R., Nov 2 2018, In : Cancer Biology and Therapy. 19, 11, p. 1023-1032 10 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Mesothelioma
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Cell Line
5 Citations (Scopus)

TRPV2 is a novel biomarker and therapeutic target in triple negative breast cancer

Elbaz, M., Ahirwar, D., Xiaoli, Z., Zhou, X., Lustberg, M., Nasser, M. W., Shilo, K. & Ganju, R. K., Sep 1 2018, In : Oncotarget. 9, 71, p. 33459-33470 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
TRPV Cation Channels
Biomarkers
Cannabidiol
Doxorubicin
2017
10 Citations (Scopus)

Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer

Elbaz, M., Ahirwar, D., Ravi, J., Nasser, M. W. & Ganju, R. K., Jan 1 2017, In : Oncotarget. 8, 18, p. 29668-29678 11 p.

Research output: Contribution to journalArticle

Cannabinoid Receptors
IGF Type 1 Receptor
Insulin-Like Growth Factor I
Epidermal Growth Factor Receptor
Epidermal Growth Factor
4 Citations (Scopus)

STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade

Varikuti, S., Oghumu, S., Elbaz, M., Volpedo, G., Ahirwar, D. K., Alarcon, P. C., Sperling, R. H., Moretti, E., Pioso, M. S., Kimble, J., Nasser, M. W., Ganju, R. K., Terrazas, C. & Satoskar, A. R., Nov 2 2017, In : OncoImmunology. 6, 11, e1361088.

Research output: Contribution to journalArticle

STAT1 Transcription Factor
Interleukin-17
Breast Neoplasms
Neoplasm Metastasis
Growth
2016
14 Citations (Scopus)

Cannabinoid receptor-2 agonist inhibits macrophage induced EMT in non-small cell lung cancer by downregulation of EGFR pathway

Ravi, J., Elbaz, M., Wani, N. A., Nasser, M. W. & Ganju, R. K., Dec 1 2016, In : Molecular Carcinogenesis. 55, 12, p. 2063-2076 14 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor Agonists
Non-Small Cell Lung Carcinoma
Down-Regulation
Macrophages
Neoplasms
14 Citations (Scopus)

Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis

Zhao, H., Ahirwar, D. K., Oghumu, S., Wilkie, T., Powell, C. A., Nasser, M. W., Satoskar, A. R., Li, D. Y. & Ganju, R. K., Feb 1 2016, In : Molecular Oncology. 10, 2, p. 272-281 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasm Metastasis
Growth
Neoplasms
Zonula Occludens-1 Protein
2015
24 Citations (Scopus)

Fatty acid binding protein 5 promotes metastatic potential of triple negative breast cancer cells through enhancing epidermal growth factor receptor stability

Powell, C. A., Nasser, M. W., Zhao, H., Wochna, J. C., Zhang, X., Shapiro, C., Shilo, K. & Ganju, R. K., Jan 1 2015, In : Oncotarget. 6, 8, p. 6373-6385 13 p.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Fatty Acid-Binding Proteins
Epidermal Growth Factor Receptor
Breast Neoplasms
Neoplasm Metastasis
9 Citations (Scopus)

miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer

Zhao, H., Wilkie, T., Deol, Y., Sneh, A., Ganju, A., Basree, M., Nasser, M. W. & Ganju, R. K., Jan 27 2015, In : Molecular cancer. 14, 1, 11.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Nude Mice
Cell Proliferation
Neoplasm Genes
51 Citations (Scopus)

Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: Novel anti-tumor mechanisms of Cannabidiol in breast cancer

Elbaz, M., Nasser, M. W., Ravi, J., Wani, N. A., Ahirwar, D. K., Zhao, H., Oghumu, S., Satoskar, A. R., Shilo, K., Carson, W. E. & Ganju, R. K., Apr 1 2015, In : Molecular Oncology. 9, 4, p. 906-919 14 p.

Research output: Contribution to journalArticle

Cannabidiol
Tumor Microenvironment
Epidermal Growth Factor
Breast Neoplasms
Triple Negative Breast Neoplasms
6 Citations (Scopus)

Non-contact method for directing electrotaxis

Ahirwar, D. K., Nasser, M. W., Jones, T. H., Sequin, E. K., West, J. D., Henthorne, T. L., Javor, J., Kaushik, A. M., Ganju, R. K. & Subramaniam, V. V., Jun 9 2015, In : Scientific reports. 5, 11005.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Intercellular Signaling Peptides and Proteins
Cell Migration Assays
Chemokines
Cell Movement
56 Citations (Scopus)

RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment

Nasser, M. W., Wani, N. A., Ahirwar, D. K., Powell, C. A., Ravi, J., Elbaz, M., Zhao, H., Padilla, L., Zhang, X., Shilo, K., Ostrowski, M., Shapiro, C., Carson, W. E. & Ganju, R. K., Mar 15 2015, In : Cancer Research. 75, 6, p. 974-985 12 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Breast Neoplasms
Neoplasm Metastasis
Growth
Neutralizing Antibodies
2014
46 Citations (Scopus)

C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment

Wani, N. A., Nasser, M. W., Ahirwar, D. K., Zhao, H., Miao, Z., Shilo, K. & Ganju, R. K., May 29 2014, In : Breast Cancer Research. 16, 3, R54.

Research output: Contribution to journalArticle

CXC Chemokines
Tumor Microenvironment
Chemokine Receptors
Breast Neoplasms
Neoplasm Metastasis
35 Citations (Scopus)

CXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model

Oghumu, S., Varikuti, S., Terrazas, C., Kotov, D., Nasser, M. W., Powell, C. A., Ganju, R. K. & Satoskar, A. R., Sep 2014, In : Immunology. 143, 1, p. 109-119 11 p.

Research output: Contribution to journalArticle

Macrophages
Breast Neoplasms
Neoplasms
Interleukin-4
Spleen
29 Citations (Scopus)

FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway

Ravi, J., Sneh, A., Shilo, K., Nasser, M. W. & Ganju, R. K., 2014, In : Oncotarget. 5, 9, p. 2475-2486 12 p.

Research output: Contribution to journalArticle

Open Access
Epidermal Growth Factor
Non-Small Cell Lung Carcinoma
Down-Regulation
G1 Phase Cell Cycle Checkpoints
Cannabinoid Receptor CB1
2013
16 Citations (Scopus)

Differential role of psoriasin (S100A7) in estrogen receptor α positive and negative breast cancer cells occur through actin remodeling

Sneh, A., Deol, Y. S., Ganju, A., Shilo, K., Rosol, T. J., Nasser, M. W. & Ganju, R. K., Apr 1 2013, In : Breast Cancer Research and Treatment. 138, 3, p. 727-739 13 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Actins
Breast Neoplasms
Matrix Metalloproteinase 9
MCF-7 Cells
2012
72 Citations (Scopus)

S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways

Nasser, M. W., Qamri, Z., Deol, Y. S., Ravi, J., Powell, C. A., Trikha, P., Schwendener, R. A., Bai, X. F., Shilo, K., Zou, X., Leone, G., Wolf, R., Yuspa, S. H. & Ganju, R. K., Feb 1 2012, In : Cancer Research. 72, 3, p. 604-615 12 p.

Research output: Contribution to journalArticle

Carcinogenesis
Breast
Up-Regulation
Breast Neoplasms
Growth
2011
66 Citations (Scopus)

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis

Preet, A., Qamri, Z., Nasser, M. W., Prasad, A., Shilo, K., Zou, X., Groopman, J. E. & Ganju, R. K., Jan 1 2011, In : Cancer Prevention Research. 4, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Growth
44 Citations (Scopus)

Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB 2 in modulating breast cancer growth and invasion

Nasser, M. W., Qamri, Z., Deol, Y. S., Smith, D., Shilo, K., Zou, X. & Ganju, R. K., Sep 13 2011, In : PloS one. 6, 9, e23901.

Research output: Contribution to journalArticle

CXCR4 Receptors
Cannabinoid Receptors
Chemokine Receptors
Crosstalk
breast neoplasms
27 Citations (Scopus)

Tumor-suppressive effects of psoriasin (S100A7) are mediated through the β-catenin/T cell factor 4 protein pathway in estrogen receptor-positive breast cancer cells

Deol, Y. S., Nasser, M. W., Yu, L., Zou, X. & Ganju, R. K., Dec 30 2011, In : Journal of Biological Chemistry. 286, 52, p. 44845-44854 10 p.

Research output: Contribution to journalArticle

Transcription Factor 7-Like 2 Protein
Catenins
Estrogen Receptors
Tumors
Cells
2009
98 Citations (Scopus)

Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer

Nasser, M. W., Raghuwanshi, S. K., Grant, D. J., Jala, V. R., Rajarathnam, K. & Richardson, R. M., Sep 1 2009, In : Journal of Immunology. 183, 5, p. 3425-3432 8 p.

Research output: Contribution to journalArticle

Neutrophil Infiltration
Interleukin-8A Receptors
Interleukin-8B Receptors
Phosphorylation
Arrestin
369 Citations (Scopus)

MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib

Bai, S., Nasser, M. W., Wang, B., Hsu, S. H., Datta, J., Kutay, H., Yadav, A., Nuovo, G., Kumar, P. & Ghoshal, K., Nov 30 2009, In : Journal of Biological Chemistry. 284, 46, p. 32015-32027 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Hepatocellular Carcinoma
Cells
Serum Response Factor
Somatomedin Receptors
127 Citations (Scopus)

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer

Qamri, Z., Preet, A., Nasser, M. W., Bass, C. E., Leone, G., Barsky, S. H. & Ganju, R. K., Nov 1 2009, In : Molecular cancer therapeutics. 8, 11, p. 3117-3129 13 p.

Research output: Contribution to journalArticle

Artificial Receptors
Cannabinoid Receptor Agonists
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Breast Neoplasms
2008
47 Citations (Scopus)

Depletion of β-arrestin-2 promotes tumor growth and angiogenesis in a murine model of lung cancer

Raghuwanshi, S. K., Nasser, M. W., Chen, X., Strieter, R. M. & Richardson, R. M., Apr 15 2008, In : Journal of Immunology. 180, 8, p. 5699-5706 8 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Growth
Neoplasms
GTP-Binding Proteins
Vascular Endothelial Growth Factor A
312 Citations (Scopus)

Down-regulation of micro-RNA-1 (miR-1) in lung cancer: Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1

Nasser, M. W., Datta, J., Nuovo, G., Kutay, H., Motiwala, T., Majumder, S., Wang, B., Suster, S., Jacob, S. T. & Ghoshal, K., Nov 28 2008, In : Journal of Biological Chemistry. 283, 48, p. 33394-33405 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Doxorubicin
Lung Neoplasms
Down-Regulation
Cells
390 Citations (Scopus)

Methylation mediated silencing of microRNA-1 gene and its role in hepatocellular carcinogenesis

Datta, J., Kutay, H., Nasser, M. W., Nuovo, G. J., Wang, B., Majumder, S., Liu, C. G., Volinia, S., Croce, C. M., Schmittgen, T. D., Ghoshal, K. & Jacob, S. T., Jul 1 2008, In : Cancer Research. 68, 13, p. 5049-5058 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Methylation
Carcinogenesis
Hepatocellular Carcinoma
Genes
2007
31 Citations (Scopus)

CXCR1 and CXCR2 activation and regulation: Role of aspartate 199 of the second extracellular loop of CXCR2 in CXCL8-mediated rapid receptor internalization

Nasser, M. W., Raghuwanshi, S. K., Malloy, K. M., Gangavarapu, P., Shim, J. Y., Rajarathnam, K. & Richardson, R. M., Mar 2 2007, In : Journal of Biological Chemistry. 282, 9, p. 6906-6915 10 p.

Research output: Contribution to journalArticle

Aspartic Acid
Interleukin-8A Receptors
Interleukin-8B Receptors
Down-Regulation
Chemical activation
2006
35 Citations (Scopus)

Activation and regulation of platelet-activating factor receptor: Role of Gi and Gq in receptor-mediated chemotactic, cytotoxic, and cross-regulatory signals

Brown, S. L., Jala, V. R., Raghuwanshi, S. K., Nasser, M. W., Haribabu, B. & Richardson, R. M., Sep 1 2006, In : Journal of Immunology. 177, 5, p. 3242-3249 8 p.

Research output: Contribution to journalArticle

Open Access
Phosphatidylinositols
GTP-Binding Proteins
Hydrolysis
Leukocytes
Pertussis Toxin
2005
30 Citations (Scopus)

Cross-desensitization among CXCR1, CXCR2, and CCR5: Role of protein kinase C-ε

Nasser, M. W., Marjoram, R. J., Brown, S. L. & Richardson, R. M., Jun 1 2005, In : Journal of Immunology. 174, 11, p. 6927-6933 7 p.

Research output: Contribution to journalArticle

Protein Kinase C
Interleukin-8B Receptors
Exocytosis
Phosphatidylinositols
Interleukin-8