Steven Heye Hinrichs, MD

Chairperson

  • 8302 Citations
  • 46 h-Index
1982 …2019
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Research Output 1982 2019

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Article
2008
23 Citations (Scopus)

Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice

Duysen, E. G., Li, B., Carlson, M., Li, Y. F., Wieseler, S., Hinrichs, S. H. & Lockridge, O., Dec 1 2008, In : Basic and Clinical Pharmacology and Toxicology. 103, 6, p. 514-521 8 p.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Cocaine
Knockout Mice
Fibrosis
Carboxylesterase
77 Citations (Scopus)

Pseudo-esterase activity of human albumin: Slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines

Lockridge, O., Xue, W., Gaydess, A., Grigoryan, H., Ding, S. J., Schopfer, L. M., Hinrichs, S. H. & Masson, P., Aug 15 2008, In : Journal of Biological Chemistry. 283, 33, p. 22582-22590 9 p.

Research output: Contribution to journalArticle

Acetylation
Esterases
Human Activities
Lysine
Tyrosine
13 Citations (Scopus)
DNA Primase
Single-Stranded DNA
Staphylococcus aureus
Escherichia coli
Bacteriophage T7
2007
11 Citations (Scopus)

Domain swapping reveals that the C- and N-terminal domains of DnaG and DnaB, respectively, are functional homologues

Chintakayala, K., Larson, M. A., Grainger, W. H., Scott, D. J., Griep, M. A., Hinrichs, S. H. & Soultanas, P., Mar 1 2007, In : Molecular Microbiology. 63, 6, p. 1629-1639 11 p.

Research output: Contribution to journalArticle

DNA Primase
DnaB Helicases
Geobacillus stearothermophilus
Adenosine Triphosphatases
Amino Acid Sequence
30 Citations (Scopus)

Genomic deletion marking an emerging subclone of Francisella tularensis subsp. holarctica in France and the Iberian Peninsula

Dempsey, M. P., Dobson, M., Zhang, C., Zhang, M., Lion, C., Gutiérrez-Martín, C. B., Iwen, P. C., Fey, P. D., Olson, M. E., Niemeyer, D., Francesconi, S., Crawford, R., Stanley, M., Rhodes, J., Wagner, D. M., Vogler, A. J., Birdsell, D., Keim, P., Johansson, A., Hinrichs, S. H. & 1 others, Benson, A. K., Nov 1 2007, In : Applied and environmental microbiology. 73, 22, p. 7465-7470 6 p.

Research output: Contribution to journalArticle

Francisella tularensis subsp. holarctica
Francisella tularensis
Iberian Peninsula
France
genomics
88 Citations (Scopus)
Ionization
Mass spectrometry
Albumins
Assays
Desorption
13 Citations (Scopus)

Molecular analysis of Francisella tularensis subspecies tularensis and holarctica

Fey, P. D., Dempsey, M. M. P., Olson, M. E., Chrustowski, M. S., Engle, J. L., Jay, J. J., Dobson, M. E., Kalasinsky, K. S., Shea, A. A., Iwen, P. C., Wickert, R. C., Francesconi, S. C., Crawford, R. M. & Hinrichs, S. H., Dec 1 2007, In : American journal of clinical pathology. 128, 6, p. 926-935 10 p.

Research output: Contribution to journalArticle

Francisella tularensis
Tularemia
Ribotyping
Minisatellite Repeats
Raman Spectrum Analysis
35 Citations (Scopus)

Myricetin inhibits Escherichia coli DnaB helicase but not primase

Griep, M. A., Blood, S., Larson, M. A., Koepsell, S. A. & Hinrichs, S. H., Nov 15 2007, In : Bioorganic and Medicinal Chemistry. 15, 22, p. 7203-7208 6 p.

Research output: Contribution to journalArticle

DnaB Helicases
DNA Primase
Escherichia coli
Inhibitory Concentration 50
Bacterial Genomes
9 Citations (Scopus)
West Nile virus
Public health
Viruses
Immunoglobulin M
Assays
2006
58 Citations (Scopus)

Designing a biocontainment unit to care for patients with serious communicable diseases: A consensus statement

Smith, P. W., Anderson, A. O., Christopher, G. W., Cieslak, T. J., Devreede, G. J., Fosdick, G. A., Greiner, C. B., Hauser, J. M., Hinrichs, S. H., Huebner, K. D., Iwen, P. C., Jourdan, D. R., Kortepeter, M. G., Landon, V. P., Lenaghan, P. A., Leopold, R. E., Marklund, L. A., Martin, J. W., Medcalf, S. J., Mussack, R. J. & 12 others, Neal, R. H., Ribner, B. S., Richmond, J. Y., Rogge, C., Roselle, G. A., Rupp, M. E., Sambol, A. R., Schaefer, J. E., Sibley, J., Streifel, A. J., Von Essen, S. G. & Warfield, K. L., Dec 1 2006, In : Biosecurity and Bioterrorism. 4, 4, p. 351-365 15 p.

Research output: Contribution to journalArticle

communicable disease
infectious disease
contagious disease
Communicable Diseases
Patient Care
3 Citations (Scopus)

First report of Mycobacterium nebraskense as a cause of human infection

Iwen, P. C., Tarantolo, S. R., Mohamed, A. M. & Hinrichs, S. H., Dec 1 2006, In : Diagnostic Microbiology and Infectious Disease. 56, 4, p. 451-453 3 p.

Research output: Contribution to journalArticle

Mycobacterium
Infection
Nontuberculous Mycobacteria
Opportunistic Infections
Emphysema
20 Citations (Scopus)
West Nile virus
Geography
Seroepidemiologic Studies
Viruses
Antibodies
27 Citations (Scopus)
Francisella tularensis
Population
Genome
Synteny
21 Citations (Scopus)
DNA Primase
Staphylococcus aureus
Escherichia coli
DNA Replication
Single-Stranded DNA
1 Citation (Scopus)
Vocabulary
Centers for Disease Control and Prevention (U.S.)
Public Health
Language Tests
Information Systems
2005
26 Citations (Scopus)

C-erb-B2 (HER2/neu) expression in synovial sarcoma of the head and neck

Olsen, R. J., Lydiatt, W. M., Koepsell, S. A., Lydiatt, D., Johansson, S. L., Naumann, S., Bridge, J. A., Neff, J. R., Hinrichs, S. H. & Tarantolo, S. R., Oct 1 2005, In : Head and Neck. 27, 10, p. 883-892 10 p.

Research output: Contribution to journalArticle

Synovial Sarcoma
Neck
Head
Neoplasms
Extremities

Community and interjurisdictional legal preparedness

Murphy, A. M., Hinrichs, S. H., Fox, P. & Stier, D., Dec 1 2005, In : Journal of Law, Medicine and Ethics. 33, 4 SUPPL., p. 73-76 4 p.

Research output: Contribution to journalArticle

Interinstitutional Relations
Mid-Atlantic Region
Public Health Administration
Disaster Planning
Community-Institutional Relations
21 Citations (Scopus)
Mycobacterium
Nucleic Acid Databases
Databases
rRNA Genes
Quality Control
10 Citations (Scopus)

Fluorometric assay for bacterial primases

Koepsell, S. A., Hanson, S., Hinrichs, S. H. & Griep, M. A., Apr 15 2005, In : Analytical Biochemistry. 339, 2, p. 353-355 3 p.

Research output: Contribution to journalArticle

DNA Primase
119 Citations (Scopus)

Low-dose chemotherapy for Epstein-Barr virus-positive post-transplantation lymphoproliferative disease in children after solid organ transplantation

Gross, T. G., Bucuvalas, J. C., Park, J. R., Greiner, T. C., Hinrich, S. H., Kaufman, S. S., Langnas, A. N., McDonald, R. A., Ryckman, F. C., Shaw, B. W., Sudan, D. L. & Lynch, J. C., Sep 20 2005, In : Journal of Clinical Oncology. 23, 27, p. 6481-6488 8 p.

Research output: Contribution to journalArticle

Organ Transplantation
Human Herpesvirus 4
Transplantation
Drug Therapy
Allografts
2004
23 Citations (Scopus)

Genome diversity among regional populations of Francisella tularensis subspecies tularensis and Francisella tularensis subspecies holarctica isolated from the US

Samrakandi, M. M., Zhang, C., Zhang, M., Nietfeldt, J., Kim, J., Iwen, P. C., Olson, M. E., Fey, P. D., Duhamel, G. E., Hinrichs, S. H., Cirillo, J. D. & Benson, A. K., Aug 1 2004, In : FEMS Microbiology Letters. 237, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

Francisella tularensis
Genome
Population
Virulence
Vaccines
14 Citations (Scopus)

Mycobacterium nebraskense sp. nov., a novel slowly growing scotochromogenic species

Mohamed, A. M., Iwen, P. C., Tarantolo, S. & Hinrichs, S. H., Nov 1 2004, In : International Journal of Systematic and Evolutionary Microbiology. 54, 6, p. 2057-2060 4 p.

Research output: Contribution to journalArticle

Mycobacterium
new species
Mycobacterium malmoense
Mycobacterium scrofulaceum
rRNA Genes
22 Citations (Scopus)
Heteroduplex Analysis
Pyrazinamide
Mycobacterium bovis
Mycobacterium tuberculosis
High Pressure Liquid Chromatography
12 Citations (Scopus)
DNA Primase
High performance liquid chromatography
High Pressure Liquid Chromatography
Assays
Scintillation Counting
105 Citations (Scopus)
Replantation
Joints
Methicillin Resistance
Infection
Bacteria
21 Citations (Scopus)

Use of a Panfungal PCR Assay for Detection of Fungal Pathogens in a Commercial Blood Culture System

Iwen, P. C., Freifeld, A. G., Bruening, T. A. & Hinrichs, S. H., May 1 2004, In : Journal of clinical microbiology. 42, 5, p. 2292-2293 2 p.

Research output: Contribution to journalArticle

Fungi
Fungemia
Polymerase Chain Reaction
Blood Culture
20 Citations (Scopus)

Utilization of the relative complexity measure to construct a phylogenetic tree for fungi

Bastola, D. R., Otu, H. H., Doukas, S. E., Sayood, K., Hinrichs, S. H. & Iwen, P. C., Feb 2004, In : Mycological Research. 108, 2, p. 117-125 9 p.

Research output: Contribution to journalArticle

Fungi
fungus
phylogenetics
fungi
Cytochromes b
2003
276 Citations (Scopus)

Comparative molecular analysis of community- or hospital-acquired methicillin-resistant Staphylococcus aureus

Fey, P. D., Saïd-Salim, B., Rupp, M. E., Hinrichs, S. H., Boxrud, D. J., Davis, C. C., Kreiswirth, B. N. & Schlievert, P. M., Jan 1 2003, In : Antimicrobial Agents and Chemotherapy. 47, 1, p. 196-203 8 p.

Research output: Contribution to journalArticle

Community Hospital
Methicillin-Resistant Staphylococcus aureus
Septic Shock
Superantigens
Chromosomes

Effects of sterilizing gamma irradiation on bloodspot newborn screening tests and whole blood cyclosporine and tacrolimus measurements

Stickle, D. F., McKenzie, D. A., Landmark, J. D., Pirruccello, S. J., Post, G. R., Iwen, P. C., Thompson, R. B. & Hinrichs, S. H., Feb 1 2003, In : American Journal of Clinical Pathology. 119, 2, p. 292-297 6 p.

Research output: Contribution to journalArticle

Postal Service
Hematologic Tests
Tacrolimus
Spores
Cyclosporine
3 Citations (Scopus)

Effects of sterilizing gamma irradiation on bloodspot newborn screening tests and whole blood cyclosporine and tacrolimus measurements

Stickle, D. F., McKenzie, D. A., Landmark, J. D., Pirruccello, S. J., Post, G. R., Iwen, P. C., Thompson, R. B. & Hinrichs, S. H., Feb 1 2003, In : American journal of clinical pathology. 119, 2, p. 292-297 6 p.

Research output: Contribution to journalArticle

Postal Service
Hematologic Tests
Tacrolimus
Spores
Cyclosporine

Evaluation of urine specimen integrity in a public health STD screening program

Birch, N. C., Stickle, D. F., Young, A., Medina, P. & Hinrichs, S. H., Apr 1 2003, In : American Journal of Clinical Pathology. 119, 4, p. 516-521 6 p.

Research output: Contribution to journalArticle

Sexually Transmitted Diseases
Public Health
Urine
Microbiology
Specific Gravity
2 Citations (Scopus)

Evaluation of urine specimen integrity in a public health STD screening program

Birch, N. C., Stickle, D. F., Young, A., Medina, P. & Hinrichs, S. H., Apr 1 2003, In : American journal of clinical pathology. 119, 4, p. 516-521 6 p.

Research output: Contribution to journalArticle

Sexually Transmitted Diseases
Public Health
Urine
Microbiology
Specific Gravity
2 Citations (Scopus)

Minimal structural elements of an inhibitory anti-ATF1/CREB single-chain antibody fragment (scFv41.4)

Olsen, R. J., Mazlo, J., Koepsell, S. A., McKeithan, T. W. & Hinrichs, S. H., Apr 2003, In : Hybridoma and Hybridomics. 22, 2, p. 65-77 13 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 1
Cyclic AMP Response Element-Binding Protein
Single-Chain Antibodies
Immunoglobulin Fragments
Clear Cell Sarcoma
37 Citations (Scopus)

PCR rapidly detects methicillin-resistant staphylococci periprosthetic infection

Tarkin, I. S., Henry, T. J., Fey, P. D., Iwen, P. C., Hinrichs, S. H. & Garvin, K. L., Sep 1 2003, In : Clinical Orthopaedics and Related Research. 414, p. 89-94 6 p.

Research output: Contribution to journalArticle

Methicillin Resistance
Staphylococcus
Polymerase Chain Reaction
Infection
Infectious Arthritis
11 Citations (Scopus)

Specific detection of human BK polyomavirus in urine samples of immunocompromised patients

Holman, C. J., Van Burik, J. A. H., Hinrichs, S. H. & Balfour, H. H., Jan 2003, In : Clinical and diagnostic laboratory immunology. 10, 1, p. 66-69 4 p.

Research output: Contribution to journalArticle

BK Virus
Immunocompromised Host
Viruses
Assays
Urine
2002
122 Citations (Scopus)

Characterization of plasmids carrying CMY-2 from expanded-spectrum cephalosporin-resistant Salmonella strains isolated in the United States between 1996 and 1998

Carattoli, A., Tosini, F., Giles, W. P., Rupp, M. E., Hinrichs, S. H., Angulo, F. J., Barrett, T. J. & Fey, P. D., May 2 2002, In : Antimicrobial Agents and Chemotherapy. 46, 5, p. 1269-1272 4 p.

Research output: Contribution to journalArticle

Ceftriaxone
Cephalosporins
Salmonella
Plasmids
DNA Sequence Analysis
10 Citations (Scopus)

Delayed diagnosis of osseous blastomycosis in two patients following environmental exposure in nonendemic areas

Veligandla, S. R., Hinrichs, S. H., Rupp, M. E., Lien, E. A., Neff, J. R. & Iwen, P. C., Oct 1 2002, In : American journal of clinical pathology. 118, 4, p. 536-541 6 p.

Research output: Contribution to journalArticle

Blastomycosis
Delayed Diagnosis
Environmental Exposure
Blastomyces
Soil
26 Citations (Scopus)

Dietary catechin delays tumor onset in a transgenic mouse model

Ebeler, S. E., Brenneman, C. A., Kim, G. S., Jewell, W. T., Webb, M. R., Chacon-Rodriguez, L., MacDonald, E. A., Cramer, A. C., Levi, A., Ebeler, J. D., Islas-Trejo, A., Kraus, A., Hinrichs, S. H. & Clifford, A. J., Oct 1 2002, In : American Journal of Clinical Nutrition. 76, 4, p. 865-872 8 p.

Research output: Contribution to journalArticle

Catechin
catechin
Transgenic Mice
Wine
animal models
62 Citations (Scopus)

Human T-lymphotropic virus type 1 oncoprotein tax promotes S-phase entry but blocks mitosis

Liang, M. H., Geisbert, T., Yao, Y., Hinrichs, S. H. & Giam, C. Z., Apr 6 2002, In : Journal of virology. 76, 8, p. 4022-4033 12 p.

Research output: Contribution to journalArticle

Human T-lymphotropic virus 1
Oncogene Proteins
taxes
S Phase
Mitosis
9 Citations (Scopus)

Molecular approaches to sarcoma therapy

Olsen, R. J., Tarantolo, S. R. & Hinrichs, S. H., Jun 22 2002, In : Sarcoma. 6, 1, p. 27-42 16 p.

Research output: Contribution to journalArticle

Sarcoma
Genes
Neoplastic Processes
Therapeutics
Philadelphia Chromosome
101 Citations (Scopus)

Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse

Duysen, E. G., Stribley, J. A., Fry, D. L., Hinrichs, S. H. & Lockridge, O., Jul 30 2002, In : Developmental Brain Research. 137, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

Acetylcholinesterase
Knockout Mice
Diet
Phenotype
Action Potentials
2001
67 Citations (Scopus)

99mTc-labeled divalent and tetravalent CC49 single-chain Fv's: Novel imaging agents for rapid in vivo localization of human colon carcinoma

Goel, A., Baranowska-Kortylewicz, J., Hinrichs, S. H., Wisecarver, J. L., Pavlinkova, G., Augustine, S., Colcher, D., Booth, B. J. M. & Batra, S. K., Jan 1 2001, In : Journal of Nuclear Medicine. 42, 10, p. 1519-1527 9 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Colon
Carcinoma
Neoplasms
Genetic Techniques
26 Citations (Scopus)

Phosphorylation of the EWS IQ domain regulates transcriptional activity of the EWS/ATF1 and EWS/FLI1 fusion proteins

Olsen, R. J. & Hinrichs, S. H., Mar 29 2001, In : Oncogene. 20, 14, p. 1756-1764 9 p.

Research output: Contribution to journalArticle

Phosphorylation
Ewing's Sarcoma
Clear Cell Sarcoma
Neoplastic Processes
Genetic Translocation
1 Citation (Scopus)

Preliminary X-ray diffraction studies of the transcriptional inhibitory antibody Fab41.4

Mazlo, J., Stanfield, R. L., Wilson, I. A., Hinrichs, S. H. & Stezowski, J. J., Mar 21 2001, In : Acta Crystallographica Section D: Biological Crystallography. 57, 3, p. 462-464 3 p.

Research output: Contribution to journalArticle

F-22 aircraft
gene expression
antibodies
Gene expression
X-Ray Diffraction
2000
273 Citations (Scopus)

Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse

Li, B., Stribley, J. A., Ticu, A., Xie, W., Schopfer, L. M., Hammond, P., Brimijoin, S., Hinrichs, S. H. & Lockridge, O., Sep 11 2000, In : Journal of Neurochemistry. 75, 3, p. 1320-1331 12 p.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Acetylcholinesterase
Knockout Mice
Tissue
Octoxynol
409 Citations (Scopus)

Ceftriaxone-resistant Salmonella infection acquired by a child from cattle

Fey, P. D., Safranek, T. J., Rupp, M. E., Dunne, E. F., Ribot, E., Iwen, P. C., Bradford, P. A., Angulo, F. J. & Hinrichs, S. H., Apr 27 2000, In : New England Journal of Medicine. 342, 17, p. 1242-1249 8 p.

Research output: Contribution to journalArticle

Ceftriaxone
Salmonella Infections
Salmonella
Salmonella enterica
Fluoroquinolones
14 Citations (Scopus)

Cutaneous infection caused by Cylindrocarpon lichenicola in a patient with acute myelogenous leukemia

Iwen, P. C., Tarantolo, S. R., Sutton, D. A., Rinaldi, M. G. & Hinrichs, S. H., Sep 26 2000, In : Journal of clinical microbiology. 38, 9, p. 3375-3378 4 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Skin
Fungi
Infection
Midwestern United States
264 Citations (Scopus)

Identification of Aspergillus species using internal transcribed spacer regions 1 and 2

Henry, T., Iwen, P. C. & Hinrichs, S. H., May 3 2000, In : Journal of clinical microbiology. 38, 4, p. 1510-1515 6 p.

Research output: Contribution to journalArticle

Aspergillus
Aspergillosis
Fungi
Nucleic Acid Databases
Aspergillus flavus
54 Citations (Scopus)

Inhibition of tumor growth and metastasis of human melanoma by intracellular anti-ATF-1 single chain Fv fragment

Jean, D., Tellez, C., Huang, S., Davis, D. W., Bruns, C. J., McConkey, D. J., Hinrichs, S. H. & Bar-Eli, M., May 18 2000, In : Oncogene. 19, 22, p. 2721-2730 10 p.

Research output: Contribution to journalArticle

Open Access
Activating Transcription Factor 1
Immunoglobulin Variable Region
Single-Chain Antibodies
Melanoma
Neoplasm Metastasis
166 Citations (Scopus)

Isolated intestinal transplantation for intestinal failure

Sudan, D. L., Kaufman, S. S., Shaw, B. W., Fox, I. J., McCashland, T. M., Schafer, D. F., Radio, S. J., Hinrichs, S. H., Vanderhoof, J. A. & Langnas, A. N., Jun 1 2000, In : American Journal of Gastroenterology. 95, 6, p. 1506-1515 10 p.

Research output: Contribution to journalArticle

Transplantation
Transplants
Parenteral Nutrition
Cytomegalovirus
Enteritis