So-Youn Kim, PhD

Assistant Professor

  • 553 Citations
  • 11 h-Index
20022019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2002 2019

2019
4 Citations (Scopus)

Inhibitors of apoptosis protect the ovarian reserve from cyclophosphamide

Luan, Y., Edmonds, M. E., Woodruff, T. K. & Kim, S. Y., Feb 1 2019, In : Journal of Endocrinology. 240, 2, p. 243-256 14 p.

Research output: Contribution to journalArticle

Cyclophosphamide
Apoptosis
Oocytes
Germ Cells
Primary Ovarian Insufficiency

Poorly-controlled type 1 diabetes mellitus impairs LH-LHCGR signaling in the ovaries and decreases female fertility in mice

Lee, J., Lee, H. C., Kim, S. Y., Cho, G. J. & Woodruff, T. K., Jul 2019, In : Yonsei Medical Journal. 60, 7, p. 667-678 12 p.

Research output: Contribution to journalArticle

Open Access
Type 1 Diabetes Mellitus
Fertility
Ovary
Oocytes
Streptozocin
2 Citations (Scopus)

Risk of Adverse Obstetric Outcomes and the Abnormal Growth of Offspring in Women with a History of Thyroid Cancer

Cho, G. J., Kim, S. Y., Lee, H. C., Lee, K. M., Han, S. W., Oh, M. J. & Woodruff, T. K., Jun 2019, In : Thyroid. 29, 6, p. 879-885 7 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Obstetrics
Growth
Pregnancy Outcome
Odds Ratio
11 Citations (Scopus)

Transient inhibition of p53 homologs protects ovarian function from two distinct apoptotic pathways triggered by anticancer therapies

Kim, S. Y., Nair, D. M., Romero, M., Serna, V. A., Koleske, A. J., Woodruff, T. K. & Kurita, T., Mar 1 2019, In : Cell Death and Differentiation. 26, 3, p. 502-515 14 p.

Research output: Contribution to journalArticle

Oocytes
Phosphorylation
Apoptosis
Checkpoint Kinase 2
Phosphotransferases
2017
9 Citations (Scopus)

Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan

Rai, R., Ghosh, A. K., Eren, M., Mackie, A. R., Levine, D. C., Kim, S. Y., Cedernaes, J., Ramirez, V., Procissi, D., Smith, L. H., Woodruff, T. K., Bass, J. & Vaughan, D. E., Nov 7 2017, In : Cell Reports. 21, 6, p. 1471-1480 10 p.

Research output: Contribution to journalArticle

Restoration
Down-Regulation
Aging of materials
Cell Aging
Cardiomegaly
2016
9 Citations (Scopus)

Constitutive activation of PI3K in oocyte induces ovarian granulosa cell tumors

Kim, S. Y., Ebbert, K., Cordeiro, M. H., Romero, M. M., Whelan, K. A., Suarez, A. A., Woodruff, T. K. & Kurita, T., Jul 1 2016, In : Cancer Research. 76, 13, p. 3851-3861 11 p.

Research output: Contribution to journalArticle

Granulosa Cell Tumor
Phosphatidylinositol 3-Kinases
Oocytes
Granulosa Cells
Cell Communication
5 Citations (Scopus)

Fertility preservation option in young women with ovarian cancer

Kim, S. Y. & Lee, J. R., Jul 2016, In : Future Oncology. 12, 14, p. 1695-1698 4 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)
Granulosa Cell Tumor
Sex Cord-Gonadal Stromal Tumors
Research
Phenotype
Mutation
2 Citations (Scopus)

Ovary is necessary to the health of uterus

Kim, S. Y., Kim, S. K., Lee, J. R. & Woodruff, T. K., May 2016, In : Journal of Gynecologic Oncology. 27, 3, e35.

Research output: Contribution to journalLetter

Uterus
Ovary
Health
50 Citations (Scopus)

Toward precision medicine for preserving fertility in cancer patients: Existing and emerging fertility preservation options for women

Kim, S. Y., Kim, S. K., Lee, J. R. & Woodruff, T. K., Mar 2016, In : Journal of Gynecologic Oncology. 27, 2

Research output: Contribution to journalReview article

Fertility Preservation
Precision Medicine
Fertility
Neoplasms
Survivors
2015
24 Citations (Scopus)

Cell autonomous phosphoinositide 3-kinase activation in oocytes disrupts normal ovarian function through promoting survival and overgrowth of ovarian follicles

Kim, S. Y., Ebbert, K., Cordeiro, M. H., Romero, M., Zhu, J., Serna, V. A., Whelan, K. A., Woodruff, T. K. & Kurita, T., Apr 1 2015, In : Endocrinology. 156, 4, p. 1464-1476 13 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Ovarian Follicle
Oocytes
Transgenic Mice
Ovary
8 Citations (Scopus)

Geography of follicle formation in the embryonic mouse ovary impacts activation pattern during the first wave of folliculogenesis

Cordeiro, M. H., Kim, S. Y., Ebbert, K., Duncan, F. E., Ramalho-Santos, J. & Woodruff, T. K., Oct 1 2015, In : Biology of reproduction. 93, 4, 88.

Research output: Contribution to journalArticle

Geography
Ovary
Meiosis
Ovarian Follicle
Tretinoin

Ovarian Follicle Biology and the Basis for Gonadotoxicity

Cordeiro, M. H., Kim, S. Y. & Woodruff, T. K., Sep 1 2015, Cancer Treatment and the Ovary: Clinical and Laboratory Analysis of Ovarian Toxicity. Elsevier Inc., p. 3-20 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ovarian Follicle
Coordination Complexes
Meiosis
Germ Cells
Cues
2013
50 Citations (Scopus)

Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network

Kim, S. Y., Cordeiro, M. H., Serna, V. A., Ebbert, K., Butler, L. M., Sinha, S., Mills, A. A., Woodruff, T. K. & Kurita, T., Aug 1 2013, In : Cell Death and Differentiation. 20, 8, p. 987-997 11 p.

Research output: Contribution to journalArticle

Platinum
Oocytes
Cisplatin
Cell Death
Apoptosis
2011
4 Citations (Scopus)

A truncated, activin-induced Smad3 isoform acts as a transcriptional repressor of FSHβ expression in mouse pituitary

Kim, S. Y., Zhu, J. & Woodruff, T. K., Aug 6 2011, In : Molecular and Cellular Endocrinology. 342, 1-2, p. 64-72 9 p.

Research output: Contribution to journalArticle

Activins
Protein Isoforms
Phosphorylation
Smad3 Protein
Exons
2009
26 Citations (Scopus)

Foxl2, a forkhead transcription factor, modulates nonclassical activity of the estrogen receptor-α

Kim, S. Y., Weiss, J., Tong, M., Laronda, M. M., Lee, E. J. & Jameson, J. L., Nov 1 2009, In : Endocrinology. 150, 11, p. 5085-5093 9 p.

Research output: Contribution to journalArticle

Forkhead Transcription Factors
Estrogen Receptors
Transcription Factor AP-1
Cyclooxygenase 2
Tamoxifen
2007
27 Citations (Scopus)

Islet cell differentiation in liver by combinatorial expression of transcription factors Neurogenin-3, BETA2, and RIPE3b1

Song, Y. D., Lee, E. J., Yashar, P., Pfaff, L. E., Kim, S. Y. & Jameson, J. L., Mar 9 2007, In : Biochemical and Biophysical Research Communications. 354, 2, p. 334-339 6 p.

Research output: Contribution to journalArticle

Transcription Factor 3
Islets of Langerhans
Liver
Dependovirus
Cell Differentiation
2006
22 Citations (Scopus)

Transcriptional regulation of glucose sensors in pancreatic β cells and liver

Im, S. S., Kim, S. Y., Kim, H. I. & Ahn, Y. H., Feb 1 2006, In : Current Diabetes Reviews. 2, 1, p. 11-18 8 p.

Research output: Contribution to journalReview article

Glucose
Liver
Homeostasis
Glycogen
Hepatocytes
2005
76 Citations (Scopus)

Glucose-stimulated upregulation of GLUT2 gene is mediated by sterol response element-binding protein-1c in the hepatocytes

Im, S. S., Kang, S. Y., Kim, S. Y., Kim, H. I., Kim, J. W., Kim, K. S. & Ahn, Y. H., Jun 1 2005, In : Diabetes. 54, 6, p. 1684-1691 8 p.

Research output: Contribution to journalArticle

Response Elements
Sterols
Hepatocytes
Carrier Proteins
Up-Regulation
23 Citations (Scopus)

Identification and characterization of peroxisome proliferator response element in the mouse GLUT2 promoter

Im, S. S., Kim, J. W., Kim, T. H., Song, X. L., Kim, S. Y., Kim, H. I. & Ahn, Y. H., Apr 30 2005, In : Experimental and Molecular Medicine. 37, 2, p. 101-110 10 p.

Research output: Contribution to journalArticle

Peroxisome Proliferators
Peroxisome Proliferator-Activated Receptors
Response Elements
Liver
rosiglitazone
2004

Erratum: SREBP-1c mediates the insulin-dependent hepatic glucokinase expression (Journal of Biological Chemistry (2004) 279 (30823-30829))

Kim, S. Y., Kim, H. I., Kim, T. H., Im, S. S., Park, S. K., Lee, I. K., Kim, K. S. & Ahn, Y. H., Aug 27 2004, In : Journal of Biological Chemistry. 279, 35, 1 p.

Research output: Contribution to journalComment/debate

Sterol Regulatory Element Binding Protein 1
Glucokinase
Insulin
Liver
40 Citations (Scopus)

Liver Glucokinase Can Be Activated by Peroxisome Proliferator-Activated Receptor-γ

Kim, S. Y., Kim, H. I., Park, S. K., Im, S. S., Li, T., Cheon, H. G. & Ahn, Y. H., Feb 1 2004, In : Diabetes. 53, SUPPL. 1, p. S66-S70

Research output: Contribution to journalArticle

Glucokinase
Peroxisome Proliferator-Activated Receptors
Thiazolidinediones
Liver
Response Elements
78 Citations (Scopus)

SREBP-1c mediates the insulin-dependent hepatic glucokinase expression

Kim, S. Y., Kim, H. I., Kim, T. H., Im, S. S., Park, S. K., Lee, I. K., Kim, K. S. & Ahn, Y. H., Jul 16 2004, In : Journal of Biological Chemistry. 279, 29, p. 30823-30829 7 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Glucokinase
Liver
Insulin
Hepatocytes
2002
6 Citations (Scopus)

Analysis of polymorphism of the GLUT2 promoter in NIDDM patients and its functional consequence to the promoter activity

Cha, J. Y., Kim, H. S., Kim, H. I., Im, S. S., Kim, S. Y., Kim, J. W., Yeh, B. I. & Ahn, Y. H., May 8 2002, In : Annals of Clinical and Laboratory Science. 32, 2, p. 114-122 9 p.

Research output: Contribution to journalArticle

Glucose Transporter Type 2
Medical problems
Polymorphism
Type 2 Diabetes Mellitus
Genes
76 Citations (Scopus)

Peroxisomal proliferator-activated receptor-γ upregulates glucokinase gene expression in β-cells

Kim, H. I., Cha, J. Y., Kim, S. Y., Kim, J. W., Roh, K. J., Seong, J. K., Lee, N. T., Choi, K. Y., Kim, K. S. & Ahn, Y. H., Jan 1 2002, In : Diabetes. 51, 3, p. 676-685 10 p.

Research output: Contribution to journalArticle

Glucokinase
Up-Regulation
Gene Expression
troglitazone
Response Elements