Shi-Hua Xiang, PhD

Assistant Professor

  • 2745 Citations
  • 25 h-Index
1993 …2019
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Research Output 1993 2019

  • 2745 Citations
  • 25 h-Index
  • 54 Article
  • 1 Comment/debate
  • 1 Review article
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Article
2019

Blocking HIV-1 infection by chromosomal integrative expression of human CD4 on the surface of lactobacillus acidophilus ATCC 4356

Wei, W., Wiggins, J., Hu, D., Vrbanac, V., Bowder, D., Mellon, M., Tager, A., Sodroski, J. & Xiang, S. H., Jan 1 2019, In : Journal of virology. 93, 8, Y.

Research output: Contribution to journalArticle

Lactobacillus acidophilus
Virus Diseases
Human immunodeficiency virus 1
HIV-1
Lactobacillus
2 Citations (Scopus)

Nucleolin is a functional binding protein for salinomycin in neuroblastoma stem cells

Wang, F., Zhou, S., Qi, D., Xiang, S. H., Wong, E. T., Wang, X., Fonkem, E., Hsieh, T. C., Yang, J., Kirmani, B., Shabb, J. B., Wu, J. M., Wu, M., Huang, J. H., Yu, W. H. & Wu, E., Feb 27 2019, In : Journal of the American Chemical Society. 141, 8, p. 3613-3622 10 p.

Research output: Contribution to journalArticle

Stem cells
Neuroblastoma
Tumors
Carrier Proteins
Stem Cells
1 Citation (Scopus)

The polar region of the HIV-1 envelope protein determines viral fusion and infectivity by stabilizing the gp120-gp41 association

Lu, W., Chen, S., Yu, J., Behrens, R., Wiggins, J., Sherer, N., Liu, S. L., Xiong, Y., Xiang, S. H. & Wu, L., Jan 1 2019, In : Journal of virology. 93, 7, e02128.

Research output: Contribution to journalArticle

viral fusion proteins
Viral Fusion Proteins
Cold Climate
Viral Envelope Proteins
Polar Regions
2018
2 Citations (Scopus)

Characterization of twin-cysteine motif in the V2-loop region of gp120 in primate lentiviruses

Bowder, D., Thompson, J., Durst, K., Hollingsead, H., Hu, D., Wei, W. & Xiang, S-H., Jun 2018, In : Virology. 519, p. 180-189 10 p.

Research output: Contribution to journalArticle

Primate Lentiviruses
Cysteine
HIV-2
HIV-1
Vaccine Potency
1 Citation (Scopus)

Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses

Bowder, D., Hollingsead, H., Durst, K., Hu, D., Wei, W., Wiggins, J., Medjahed, H., Finzi, A., Sodroski, J. & Xiang, S-H., Aug 2018, In : Virology. 521, p. 158-168 11 p.

Research output: Contribution to journalArticle

Primate Lentiviruses
HIV-1
Glycoproteins
env Gene Products
Virus Internalization
11 Citations (Scopus)

Discovery of a non-nucleoside RNA polymerase inhibitor for blocking Zika virus replication through in silico screening

Pattnaik, A., Palermo, N., Sahoo, B. R., Yuan, Z., Hu, D., Annamalai, A. S., Vu, H. L., Correas, I., Prathipati, P. K., Destache, C. J., Li, Q., Osorio, F. A., Pattnaik, A. K. & Xiang, S-H., Mar 2018, In : Antiviral Research. 151, p. 78-86 9 p.

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Virus Replication
Computer Simulation
RNA Replicase
Catalytic Domain
3 Citations (Scopus)

Persistence of SIV in the brain of SIV-infected Chinese rhesus macaques with or without antiretroviral therapy

Perez, S., Johnson, A. M., Xiang, S-H., Li, J., Foley, B. T., Doyle-Meyers, L., Panganiban, A., Kaur, A., Veazey, R. S., Wu, Y. & Ling, B., Feb 1 2018, In : Journal of neurovirology. 24, 1, p. 62-74 13 p.

Research output: Contribution to journalArticle

Macaca mulatta
Central Nervous System
Brain
Microglia
HIV
2017
9 Citations (Scopus)

Mechanistic understanding of N-glycosylation in Ebola virus glycoprotein maturation and function

Wang, B., Wang, Y., Frabutt, D. A., Zhang, X., Yao, X., Hu, D., Zhang, Z., Liu, C., Zheng, S., Xiang, S-H. & Zheng, Y. H., Apr 7 2017, In : Journal of Biological Chemistry. 292, 14, p. 5860-5870 11 p.

Research output: Contribution to journalArticle

Ebolavirus
Glycosylation
Viruses
Glycoproteins
Calreticulin
2 Citations (Scopus)

Tryptophan 375 stabilizes the outer-domain core of gp120 for HIV vaccine immunogen design

Hu, D., Bowder, D., Wei, W., Thompson, J., Wilson, M. A. & Xiang, S-H., May 25 2017, In : Vaccine. 35, 23, p. 3067-3075 9 p.

Research output: Contribution to journalArticle

HIV Envelope Protein gp120
AIDS Vaccines
Tryptophan
Disulfides
tryptophan
28 Citations (Scopus)

Zika virus encoding nonglycosylated envelope protein is attenuated and defective in neuroinvasion

Annamalai, A. S., Pattnaik, A., Sahoo, B. R., Muthukrishnan, E., Natarajan, S. K., Steffen, D. J., Vu, H. L., Delhon, G., Osorio, F. A., Petro, T. M., Xiang, S-H. & Pattnaik, A. K., Dec 1 2017, In : Journal of virology. 91, 23, e01348-17.

Research output: Contribution to journalArticle

Zika virus
glycosylation
Glycosylation
Virulence
Proteins
2016
9 Citations (Scopus)

A highly conserved gp120 inner domain residue modulates Env conformation and trimer stability

Ding, S., Tolbert, W. D., Prévost, J., Pacheco, B., Coutu, M., Debbeche, O., Xiang, S-H., Pazgier, M. & Finzi, A., Jan 1 2016, In : Journal of virology. 90, 19, p. 8395-8409 15 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
hydrophobicity
Hydrophobic and Hydrophilic Interactions
antibodies
aromatic compounds
21 Citations (Scopus)

From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR

Lin, B., Xu, M., Zhu, X., Wu, Y., Liu, X., Zhangsun, D., Hu, Y., Xiang, S-H., Kasheverov, I. E., Tsetlin, V. I., Wang, X. & Luo, S., Mar 1 2016, In : Scientific reports. 6, 22349.

Research output: Contribution to journalArticle

Conotoxins
Aplysia
Acetylcholine
Carrier Proteins
Nicotinic Receptors
2 Citations (Scopus)

Genome-wide search for host association factors during ovine progressive pneumonia virus infection

Thompson, J., Ma, F., Quinn, M. & Xiang, S-H., Mar 2016, In : PloS one. 11, 3, e0150344.

Research output: Contribution to journalArticle

maedi-visna disease
Virus Diseases
Viruses
Sheep
Pneumonia
3 Citations (Scopus)

Lineage-specific differences between the gp120 inner domain layer 3 of human immunodeficiency virus and that of simian immunodeficiency virus

Ding, S., Medjahed, H., Prévost, J., Coutu, M., Xiang, S-H. & Finzi, A., Jan 1 2016, In : Journal of virology. 90, 22, p. 10065-10073 9 p.

Research output: Contribution to journalArticle

Open Access
Simian immunodeficiency virus
Simian Immunodeficiency Virus
Human immunodeficiency virus
Human immunodeficiency virus 1
HIV-1
3 Citations (Scopus)

Sulfotyrosine dipeptide: Synthesis and evaluation as HIV-entry inhibitor

Ju, T., Hu, D., Xiang, S-H. & Guo, J., Oct 1 2016, In : Bioorganic Chemistry. 68, p. 105-111 7 p.

Research output: Contribution to journalArticle

HIV Fusion Inhibitors
Dipeptides
Viruses
HIV-1
Drug therapy
2015
5 Citations (Scopus)

Escherichia coli surface display of single-chain antibody VRC01 against HIV-1 infection

Wang, L. X., Mellon, M., Bowder, D., Quinn, M., Shea, D., Wood, C. & Xiang, S-H., Jan 5 2015, In : Virology. 475, p. 179-186 8 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Virus Diseases
HIV-1
Escherichia coli
Bacteria
2014
46 Citations (Scopus)

Sumoylation differentially regulates Sp1 to control cell differentiation

Gong, L., Ji, W. K., Hu, X. H., Hu, W. F., Tang, X. C., Huang, Z. X., Li, L., Liu, M., Xiang, S-H., Wu, E., Woodward, Z., Liu, Y. Z., Nguyen, Q. D. & Li, D. W. C., Apr 15 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 15, p. 5574-5579 6 p.

Research output: Contribution to journalArticle

Sumoylation
Lenses
Cell Differentiation
Ubiquitin
Crystallins
2013
14 Citations (Scopus)

A Twin-Cysteine Motif in the V2 Region of gp120 Is Associated with SIV Envelope Trimer Stabilization

Bohl, C., Bowder, D., Thompson, J., Abrahamyan, L., Gonzalez-Ramirez, S., Mao, Y., Sodroski, J., Wood, C. & Xiang, S-H., Jul 23 2013, In : PloS one. 8, 7, e69406.

Research output: Contribution to journalArticle

Cysteine
cysteine
Viruses
Stabilization
Human immunodeficiency virus 2
9 Citations (Scopus)

Characterization of a dual-tropic Human immunodeficiency virus (HIV-1) strain derived from the prototypical X4 isolate HXBc2

Xiang, S-H., Pacheco, B., Bowder, D., Yuan, W. & Sodroski, J., Jan 29 2013, In : Virology. 438, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

HIV-1
HIV
Viruses
Tropism
Glycoproteins
71 Citations (Scopus)

Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer

Mao, Y., Wang, L., Gu, C., Herschhorn, A., Désormeaux, A., Finzi, A., Xiang, S-H. & Sodroski, J. G., Jul 23 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 30, p. 12438-12443 6 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
HIV-1
Glycoproteins
CCR5 Receptors
env Gene Products
3 Citations (Scopus)

Recent advances on the use of structural biology for the design of novel envelope Immunogens of HIV-1

Xiang, S-H., Jan 1 2013, In : Current HIV research. 11, 6, p. 464-472 9 p.

Research output: Contribution to journalArticle

AIDS Vaccines
HIV-1
Antigens
Pandemics
Acquired Immunodeficiency Syndrome
33 Citations (Scopus)

The highly conserved layer-3 component of the hiv-1 gp120 inner domain is critical for CD4-required conformational transitions

Désormeaux, A., Coutu, M., Medjahed, H., Pacheco, B., Herschhorn, A., Gu, C., Xiang, S-H., Mao, Y., Sodroski, J. & Finzi, A., Mar 1 2013, In : Journal of virology. 87, 5, p. 2549-2562 14 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
glycoproteins
Virus Internalization
Glycoproteins
2012
5 Citations (Scopus)

Critical role of leucine-valine change in distinct low pH requirements for membrane fusion between two related retrovirus envelopes

Côté, M., Zheng, Y. M., Li, K., Xiang, S-H., Albritton, L. M. & Liu, S. L., Mar 2 2012, In : Journal of Biological Chemistry. 287, 10, p. 7640-7651 12 p.

Research output: Contribution to journalArticle

Membrane Fusion
Valine
Retroviridae
Viruses
Leucine
25 Citations (Scopus)

Identification of molecular determinants from Moloney leukemia virus 10 homolog (MOV10) protein for virion packaging and anti-HIV-1 activity

Abudu, A., Wang, X., Dang, Y., Zhou, T., Xiang, S-H. & Zheng, Y. H., Jan 6 2012, In : Journal of Biological Chemistry. 287, 2, p. 1220-1228 9 p.

Research output: Contribution to journalArticle

Moloney murine leukemia virus
Product Packaging
Viruses
Virion
HIV-1
20 Citations (Scopus)

Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding

Finzi, A., Pacheco, B., Xiang, S. H., Pancera, M., Herschhorn, A., Wang, L., Zeng, X., Desormeaux, A., Kwong, P. D. & Sodroski, J., Sep 1 2012, In : Journal of virology. 86, 17, p. 8974-8986 13 p.

Research output: Contribution to journalArticle

Simian immunodeficiency virus
Human immunodeficiency virus
Human immunodeficiency virus 1
HIV-1
HIV
116 Citations (Scopus)

Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer

Mao, Y., Wang, L., Gu, C., Herschhorn, A., Xiang, S-H., Haim, H., Yang, X. & Sodroski, J., Sep 1 2012, In : Nature Structural and Molecular Biology. 19, 9, p. 893-899 7 p.

Research output: Contribution to journalArticle

HIV-1
Glycoproteins
Membranes
env Gene Products
Viral Envelope Proteins
2010
56 Citations (Scopus)

A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer

Xiang, S. H., Finzi, A., Pacheco, B., Alexander, K., Yuan, W., Rizzuto, C., Huang, C. C., Kwong, P. D. & Sodroski, J., Apr 1 2010, In : Journal of virology. 84, 7, p. 3147-3161 15 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus
Human immunodeficiency virus 1
HIV-1
glycoproteins
Chemokine Receptors
126 Citations (Scopus)

Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

Finzi, A., Xiang, S. H., Pacheco, B., Wang, L., Haight, J., Kassa, A., Danek, B., Pancera, M., Kwong, P. D. & Sodroski, J., Mar 12 2010, In : Molecular Cell. 37, 5, p. 656-667 12 p.

Research output: Contribution to journalArticle

HIV-1
Glycoproteins
Virus Internalization
CD4 Antigens
Cell Fusion
2009
36 Citations (Scopus)

Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain

Kassa, A., Madani, N., Schön, A., Haim, H., Finzi, A., Xiang, S. H., Wang, L., Princiotto, A., Pancera, M., Courter, J., Smith, A. B., Freire, E., Kwong, P. D. & Sodroski, J., Sep 22 2009, In : Journal of virology. 83, 17, p. 8364-8378 15 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
glycoproteins
Glycoproteins
CD4 Antigens
9 Citations (Scopus)

X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens

Hovav, A. H., Santosuosso, M., Bivas-Benita, M., Plair, A., Cheng, A., Elnekave, M., Righi, E., Chen, T., Kashiwagi, S., Panas, M. W., Xiang, S. H., Furmanov, K., Letvin, N. L. & Poznansky, M. C., Nov 1 2009, In : Journal of virology. 83, 21, p. 10941-10950 10 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
immune response
antigens
Antigens
2008
13 Citations (Scopus)

Adaptation of the human immunodeficiency virus type 1 envelope glycoproteins to New World monkey receptors

Pacheco, B., Basmaciogullari, S., Labonte, J. A., Xiang, S. H. & Sodroski, J., Jan 1 2008, In : Journal of virology. 82, 1, p. 346-357 12 p.

Research output: Contribution to journalArticle

Platyrrhini
Cebidae
Human immunodeficiency virus 1
HIV-1
glycoproteins
126 Citations (Scopus)

Small-Molecule CD4 Mimics Interact with a Highly Conserved Pocket on HIV-1 gp120

Madani, N., Schön, A., Princiotto, A. M., LaLonde, J. M., Courter, J. R., Soeta, T., Ng, D., Wang, L., Brower, E. T., Xiang, S. H., Do Kwon, Y., Huang, C. C., Wyatt, R., Kwong, P. D., Freire, E., Smith, A. B. & Sodroski, J., Nov 12 2008, In : Structure. 16, 11, p. 1689-1701 13 p.

Research output: Contribution to journalArticle

CD4 Antigens
HIV-1
Virus Internalization
Glycoproteins
CCR5 Receptors
2007
89 Citations (Scopus)

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: Antigenicity, biophysics, and immunogenicity

Dey, B., Pancera, M., Svehla, K., Shu, Y., Xiang, S. H., Vainshtein, J., Li, Y., Sodroski, J., Kwong, P. D., Mascola, J. R. & Wyatt, R., Jun 1 2007, In : Journal of virology. 81, 11, p. 5579-5593 15 p.

Research output: Contribution to journalArticle

Biophysics
biophysics
Human immunodeficiency virus 1
Neutralizing Antibodies
neutralizing antibodies
26 Citations (Scopus)

Functional interplay between the B-box 2 and the B30.2(SPRY) domains of TRIM5α

Li, X., Song, B., Xiang, S. H. & Sodroski, J., Sep 30 2007, In : Virology. 366, 2, p. 234-244 11 p.

Research output: Contribution to journalArticle

Capsid
HIV-1
Cyclophilin A
B30.2-SPRY Domain
Infection
60 Citations (Scopus)

Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5α B-box 2 domain

Diaz-Griffero, F., Kar, A., Perron, M., Xiang, S. H., Javanbakht, H., Li, X. & Sodroski, J., Oct 1 2007, In : Journal of virology. 81, 19, p. 10362-10378 17 p.

Research output: Contribution to journalArticle

Proteasome Inhibitors
proteasome endopeptidase complex
arginine
Arginine
capsid
616 Citations (Scopus)

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Zhou, T., Xu, L., Dey, B., Hessell, A. J., Van Ryk, D., Xiang, S. H., Yang, X., Zhang, M. Y., Zwick, M. B., Arthos, J., Burton, D. R., Dimitrov, D. S., Sodroski, J., Wyatt, R., Nabel, G. J. & Kwong, P. D., Feb 15 2007, In : Nature. 445, 7129, p. 732-737 6 p.

Research output: Contribution to journalArticle

HIV-1
Epitopes
CD4 Antigens
Antibodies
Antibody Binding Sites
320 Citations (Scopus)

Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4

Huang, C. C., Lam, S. N., Acharya, P., Tang, M., Xiang, S. H., Hussan, S. S. U., Stanfield, R. L., Robinson, J., Sodroski, J., Wilson, I. A., Wyatt, R., Bewley, C. A. & Kwong, P. D., Sep 28 2007, In : Science. 317, 5846, p. 1930-1934 5 p.

Research output: Contribution to journalArticle

Tyrosine
HIV-1
Antibodies
HIV Envelope Protein gp120
CCR5 Receptors
2006
26 Citations (Scopus)

DNA vaccination with CCL2 DNA modified by the addition of an adjuvant epitope protects against "nonimmune" toxic renal injury

Zheng, G., Wang, Y., Xiang, S. H., Tay, Y. C., Wu, H., Watson, D., Coombes, J., Rangan, G. K., Alexander, S. I. & Harris, D. C. H., Feb 1 2006, In : Journal of the American Society of Nephrology. 17, 2, p. 465-474 10 p.

Research output: Contribution to journalArticle

DNA Vaccines
Poisons
Epitopes
Vaccination
Autoantibodies
2005
32 Citations (Scopus)

Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody

Xiang, S. H., Farzan, M., Si, Z., Madani, N., Wang, L., Rosenberg, E., Robinson, J. & Sodroski, J., May 1 2005, In : Journal of virology. 79, 10, p. 6068-6077 10 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
Neutralizing Antibodies
neutralizing antibodies
HIV-1
monoclonal antibodies
2003
47 Citations (Scopus)

Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base

Cavacini, L., Duval, M., Song, L., Sangster, R., Xiang, S. H., Sodroski, J. & Posner, M., Mar 28 2003, In : AIDS. 17, 5, p. 685-689 5 p.

Research output: Contribution to journalArticle

Epitopes
Antibodies
Virion
Monoclonal Antibodies
Antibody Binding Sites
68 Citations (Scopus)

Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strains

Xiang, S. H., Wang, L., Abreu, M., Huang, C. C., Kwong, P. D., Rosenberg, E., Robinson, J. E. & Sodroski, J., Oct 10 2003, In : Virology. 315, 1, p. 124-134 11 p.

Research output: Contribution to journalArticle

Epitope Mapping
HIV-1
Monoclonal Antibodies
Antibodies
Chemokine Receptors
43 Citations (Scopus)

Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia

Marden, N. Y., Fiala-Beer, E., Xiang, S. H. & Murray, M., Aug 1 2003, In : Biochemical Journal. 373, 3, p. 669-680 12 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Down-Regulation
Genes
Transfection
Chemical activation
2002
128 Citations (Scopus)

Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies

Xiang, S. H., Doka, N., Choudhary, R. K., Sodroski, J. & Robinson, J. E., Jan 1 2002, In : AIDS Research and Human Retroviruses. 18, 16, p. 1207-1217 11 p.

Research output: Contribution to journalArticle

HIV Envelope Protein gp120
HIV-1
Epitopes
Monoclonal Antibodies
Chemokine Receptors
151 Citations (Scopus)

Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein

Xiang, S. H., Kwong, P. D., Gupta, R., Rizzuto, C. D., Casper, D. J., Wyatt, R., Wang, L., Hendrickson, W. A., Doyle, M. L. & Sodroski, J., Oct 1 2002, In : Journal of virology. 76, 19, p. 9888-9899 12 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
glycoproteins
Glycoproteins
antibodies
1998
10 Citations (Scopus)

Identification of a novel transcriptional silencer in the protein-coding region of the human CYP2 C9 gene

Xiang, S. H., Parsons, H. K. & Murray, M., Mar 16 1998, In : Gene. 209, 1-2, p. 123-129 7 p.

Research output: Contribution to journalArticle

Hep G2 Cells
Nuclear Proteins
Open Reading Frames
Carrier Proteins
Southwestern Blotting
1997
13 Citations (Scopus)

Coinfection and Genetic Recombination between HIV-1 Strains: Possible Biological Implications in Australia and South East Asia

Saksena, N. K., Wang, B., Ge, Y. C., Xiang, S. H., Dwyer, D. E. & Cunningham, A. L., Jan 1 1997, In : Annals of the Academy of Medicine Singapore. 26, 1, p. 121-127 7 p.

Research output: Contribution to journalArticle

South Australia
Far East
Coinfection
Genetic Recombination
HIV-1
13 Citations (Scopus)

Molecular analyses of human immunodeficiency virus type 1 V3 region quasispecies derived from plasma and peripheral blood mononuclear cells of the first long-term-nonprogressing mother and child pair

Wang, B., Ge, Y. C., Jozwiak, R., Bolton, W., Palasanthiran, P., Ziegler, J., Chang, J., Xiang, S. H., Cunningham, A. L. & Saksena, N. K., Jan 1 1997, In : Journal of Infectious Diseases. 175, 6, p. 1510-1515 6 p.

Research output: Contribution to journalArticle

Open Access
HIV-1
Blood Cells
Mothers
Tropism
Genetic Heterogeneity
17 Citations (Scopus)

Region-specific changes, gene duplications, and random deletions in the nef gene from HIV type 1-infected brain tissues and blood of a demented patient

Saksena, N. K., Wang, B., Ge, Y. C., Chang, J., Dwyer, D. E., Xiang, S. H., Packham, D. R., Randle, C. & Cunningham, A. L., Jan 1 1997, In : AIDS Research and Human Retroviruses. 13, 1, p. 111-116 6 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
nef Genes
AIDS Dementia Complex
Mononuclear Leukocytes
Gene Duplication
11 Citations (Scopus)

RNA and DNA sequence analysis of the nef gene of HIV type 1 strains from the first HIV type 1-infected long-term nonprogressing mother-child pair

Saksena, N. K., Ge, Y. C., Wang, B., Xiang, S. H., Ziegler, J., Palasanthiran, P., Bolton, W. & Cunningham, A. L., May 20 1997, In : AIDS Research and Human Retroviruses. 13, 8, p. 729-732 4 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Molecular Sequence Data
nef Genes
nef Gene Products
Virus Latency
9 Citations (Scopus)

Simian T cell leukemia virus type I from naturally infected feral monkeys from central and West Africa encodes a 91-amino acid p12 (ORF-I) protein as opposed to a 99-amino acid protein encoded by HTLV type I from humans

Saksena, N. K., Srinivasan, A., Ying Chun Ge, C. G., Xiang, S. H., Azad, A., Bolton, W., Herve, V., Reddy, S., Diop, O., Miranda-Saksena, M., Rawlinson, W. D., Vandamme, M. & Barre-Sinoussi, F., Jan 1 1997, In : AIDS Research and Human Retroviruses. 13, 5, p. 425-432 8 p.

Research output: Contribution to journalArticle

Simian T-lymphotropic virus 1
Central Africa
T-Cell Leukemia
Human T-lymphotropic virus 1
Western Africa