Shannon M Buckley-McKeown, PhD

Assistant Professor

  • 614 Citations
  • 12 h-Index
20022017
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Research Output 2002 2017

  • 614 Citations
  • 12 h-Index
  • 14 Article
  • 2 Comment/debate
  • 1 Chapter
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Article
2017
76 Citations (Scopus)

Easi-CRISPR: A robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins

Quadros, R. M., Miura, H., Harms, D. W., Akatsuka, H., Sato, T., Aida, T., Redder, R., Richardson, G. P., Inagaki, Y., Sakai, D., Buckley-McKeown, S. M., Seshacharyulu, P., Batra, S. K., Behlke, M. A., Zeiner, S. A., Jacobi, A. M., Izu, Y., Thoreson, W. B., Urness, L. D., Mansour, S. L. & 2 others, Ohtsuka, M. & Gurumurthy, C. B., May 17 2017, In : Genome biology. 18, 1, 92.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
ribonucleoproteins
single-stranded DNA
Ribonucleoproteins
allele
2016
16 Citations (Scopus)

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

Strikoudis, A., Lazaris, C., Trimarchi, T., Galvao Neto, A. L., Yang, Y., Ntziachristos, P., Rothbart, S., Buckley-McKeown, S. M., Dolgalev, I., Stadtfeld, M., Strahl, B. D., Dynlacht, B. D., Tsirigos, A. & Aifantis, I., Oct 27 2016, In : Nature Cell Biology. 18, 11, p. 1127-1138 12 p.

Research output: Contribution to journalArticle

Fingers
Cell Differentiation
Embryonic Stem Cells
Myoblasts
Proteins
2015
11 Citations (Scopus)

The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis

Gao, J., Buckley-McKeown, S. M., Cimmino, L., Guillamot, M., Strikoudis, A., Cang, Y., Goff, S. P. & Aifantis, I., Nov 27 2015, In : eLife. 4, NOVEMBER2015, e07539.

Research output: Contribution to journalArticle

Adult Stem Cells
Embryonic Stem Cells
Ligases
Ubiquitin
Stem cells
2013
17 Citations (Scopus)

Anovel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression

Khurana, S., Buckley, S., Schouteden, S., Ekker, S., Petryk, A., Delforge, M., Zwijsen, A. & Verfaillie, C. M., Jan 31 2013, In : Blood. 121, 5, p. 781-790 10 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Hematopoietic Stem Cells
Stem cells
Integrins
Microphthalmia-Associated Transcription Factor
23 Citations (Scopus)

Glypican-3-mediated inhibition of CD26 by TFPI: A novel mechanism in hematopoietic stem cell homing and maintenance

Khurana, S., Margamuljana, L., Joseph, C., Schouteden, S., Buckley, S. M. & Verfaillie, C. M., Jan 1 2013, In : Blood. 121, 14, p. 2587-2595 9 p.

Research output: Contribution to journalArticle

Glypicans
Hematopoietic Stem Cells
Stem cells
Bone
Maintenance
58 Citations (Scopus)

Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression

Reavie, L., Buckley, S. M., Loizou, E., Takeishi, S., Aranda-Orgilles, B., Ndiaye-Lobry, D., Abdel-Wahab, O., Ibrahim, S., Nakayama, K. I. & Aifantis, I., Mar 18 2013, In : Cancer Cell. 23, 3, p. 362-375 14 p.

Research output: Contribution to journalArticle

Ubiquitination
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia
Ligases
Ubiquitin
2012
128 Citations (Scopus)

Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system

Buckley, S. M., Aranda-Orgilles, B., Strikoudis, A., Apostolou, E., Loizou, E., Moran-Crusio, K., Farnsworth, C. L., Koller, A. A., Dasgupta, R., Silva, J. C., Stadtfeld, M., Hochedlinger, K., Chen, E. I. & Aifantis, I., Dec 7 2012, In : Cell Stem Cell. 11, 6, p. 783-798 16 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Ubiquitin
Post Translational Protein Processing
Embryonic Stem Cells
Cell Differentiation
2011
21 Citations (Scopus)

Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line

Buckley, S. M., Ulloa-Montoya, F., Abts, D., Oostendorp, R. A. J., Dzierzak, E., Ekker, S. C. & Verfaillie, C. M., Jan 2011, In : Experimental Hematology. 39, 1, p. 114-123.e5

Research output: Contribution to journalArticle

Stromal Cells
Hematopoietic Stem Cells
Maintenance
Cell Line
Bone Marrow Cells
2010
68 Citations (Scopus)

Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex

Reavie, L., Gatta, G. D., Crusio, K., Aranda-Orgilles, B., Buckley, S. M., Thompson, B., Lee, E., Gao, J., Bredemeyer, A. L., Helmink, B. A., Zavadil, J., Sleckman, B. P., Palomero, T., Ferrando, A. & Aifantis, I., Mar 1 2010, In : Nature Immunology. 11, 3, p. 207-215 9 p.

Research output: Contribution to journalArticle

Ligases
Hematopoietic Stem Cells
Ubiquitin
Cell Differentiation
Proto-Oncogene Proteins c-myc
2008
38 Citations (Scopus)

Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver

Sahin, M. B., Schwartz, R. E., Buckley, S. M., Heremans, Y., Chase, L., Hu, W. S. & Verfaillie, C. M., Mar 1 2008, In : Liver Transplantation. 14, 3, p. 333-345 13 p.

Research output: Contribution to journalArticle

Stem Cells
Liver
Population
Albumins
Urea
2007
9 Citations (Scopus)

Gene transfer via nucleofection into adult and embryonic stem cells.

Lakshmipathy, U., Buckley, S. & Verfaillie, C., 2007, In : Methods in molecular biology (Clifton, N.J.). 407, p. 115-126 12 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Embryonic Stem Cells
Stem Cells
Genes
Transfection
89 Citations (Scopus)

Hematopoietic reconstitution by multipotent adult progenitor cells: Precursors to long-term hematopoietic stem cells

Serafini, M., Dylla, S. J., Oki, M., Heremans, Y., Tolar, J., Jiang, Y., Buckley, S. M., Pelacho, B., Burns, T. C., Frommer, S., Rossi, D. J., Bryder, D., Panoskaltsis-Mortari, A., O'Shaughnessy, M. J., Nelson-Holte, M., Fine, G. C., Weissman, I. L., Blazar, B. R. & Verfaillie, C. M., Jan 22 2007, In : Journal of Experimental Medicine. 204, 1, p. 129-139 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem Cells
Green Fluorescent Proteins
Hematopoiesis
Bone Marrow Cells
2003
41 Citations (Scopus)

Homing defect of cultured human hematopoietic cells in the NOD/SCID mouse is mediated by Fas/CD95

Liu, B., Buckley, S. M., Lewis, I. D., Goldman, A. I., Wagner, J. E. & Van Der Loo, J. C. M., Sep 1 2003, In : Experimental Hematology. 31, 9, p. 824-832 9 p.

Research output: Contribution to journalArticle

SCID Mice
Fetal Blood
Transplantation
Apoptosis
Indium
2002
18 Citations (Scopus)
Gibbon ape leukemia virus
Granulocyte Colony-Stimulating Factor
Cytokines
Genes
Thrombopoietin