Ronald Cerny, PhD &ndash; Research Output

2019

Remodeling of Chlamydomonas Metabolism Using Synthetic Inducers Results in Lipid Storage during Growth

Wase, N., Tu, B., Rasineni, G. K., Cerny, R., Grove, R., Adamec, J., Black, P. N. & DiRusso, C. C., Nov 1 2019, In : Plant physiology. 181, 3, p. 1029-1049 21 p.

Research output: Contribution to journal › Article

Open Access

Chlamydomonas

Lipids

metabolism

Starch

lipids

2018

3 Citations (Scopus)

Combining 2-DE immunoblots and mass spectrometry to identify putative soybean (Glycine max) allergens

Lu, M., Jin, Y., Cerny, R., Ballmer-Weber, B. & Goodman, R. E., Jun 2018, In : Food and Chemical Toxicology. 116, p. 207-215 9 p.

Research output: Contribution to journal › Article

allergens

Soybeans

Allergens

Glycine

Mass spectrometry

2017

12 Citations (Scopus)

Fluorescent protein-based turn-on probe through a general protection-deprotection design strategy

Shang, X., Wang, N., Cerny, R., Niu, W. & Guo, J., Jul 28 2017, In : ACS Sensors. 2, 7, p. 961-966 6 p.

Research output: Contribution to journal › Article

proteins

Proteins

probes

sensors

Sensors

25 Citations (Scopus)

Fluorogenic protein labeling using a genetically encoded unstrained alkene

Shang, X., Song, X., Faller, C., Lai, R. Y., Li, H., Cerny, R., Niu, W. & Guo, J., Jan 1 2017, In : Chemical Science. 8, 2, p. 1141-1145 5 p.

Research output: Contribution to journal › Article

Styrene

Alkenes

Labeling

Amber

Protein folding

7 Citations (Scopus)

Glucose Metabolism and AMPK Signaling Regulate Dopaminergic Cell Death Induced by Gene (α-Synuclein)-Environment (Paraquat) Interactions

Anandhan, A., Lei, S., Levytskyy, R., Pappa, A., Panayiotidis, M. I., Cerny, R., Khalimonchuk, O., Powers, R. & Franco-Cruz, R., Jul 1 2017, In : Molecular Neurobiology. 54, 5, p. 3825-3842 18 p.

Research output: Contribution to journal › Article

Synucleins

Paraquat

Adenosine Monophosphate

Protein Kinases

Cell Death

The NMR solution structure and function of RPA3313: a putative ribosomal transport protein from Rhodopseudomonas palustris

Catazaro, J., Lowe, A. J., Cerny, R. & Powers, R., Jan 1 2017, In : Proteins: Structure, Function and Bioinformatics. 85, 1, p. 93-102 10 p.

Research output: Contribution to journal › Article

Rhodopseudomonas

Ribosomal Proteins

Carrier Proteins

Nuclear magnetic resonance

Proteins

2016

2 Citations (Scopus)

A photoactivatable Src homology 2 (SH2) domain

Song, X., Shang, X., Ju, T., Cerny, R., Niu, W. & Guo, J., Jan 1 2016, In : RSC Advances. 6, 56, p. 51120-51124 5 p.

Research output: Contribution to journal › Article

Phosphotyrosine

Proteins

Signal transduction

Receptor Protein-Tyrosine Kinases

Peptides

8 Citations (Scopus)

Systematic evolution and study of UAGN decoding tRNAs in a genomically recoded bacteria

Wang, N., Shang, X., Cerny, R., Niu, W. & Guo, J., Feb 24 2016, In : Scientific reports. 6, 21898.

Research output: Contribution to journal › Article

Anticodon

Transfer RNA

Codon

Genetic Code

Bacteria

2015

6 Citations (Scopus)

Comparison of Mannose, Ethylene Glycol, and Methoxy-Terminated Diluents on Specificity and Selectivity of Electrochemical Peptide-Based Sensors

Zaitouna, A. J., Joyce, J., Cerny, R., Dussault, P. H. & Lai, R. Y., Jul 7 2015, In : Analytical chemistry. 87, 13, p. 6966-6973 8 p.

Research output: Contribution to journal › Article

Ethylene Glycol

Mannose

Peptides

Sensors

Self assembled monolayers

16 Citations (Scopus)

Sphingolipid metabolism is strikingly different between pollen and leaf in Arabidopsis as revealed by compositional and gene expression profiling

Luttgeharm, K. D., Kimberlin, A. N., Cahoon, R. E., Cerny, R., Napier, J. A., Markham, J. E. & Cahoon, E. B., Jul 2015, In : Phytochemistry. 115, 1, p. 121-129 9 p.

Research output: Contribution to journal › Article

sphingolipids

Sphingolipids

Gene Expression Profiling

Pollen

Arabidopsis

6 Citations (Scopus)

Transient sampling of aggregation-prone conformations causes pathogenic instability of a parkinsonian mutant of DJ-1 at physiological temperature

Milkovic, N. M., Catazaro, J., Lin, J., Halouska, S., Kizziah, J. L., Basiaga, S., Cerny, R., Powers, R. & Wilson, M. A., Oct 1 2015, In : Protein Science. 24, 10, p. 1671-1685 15 p.

Research output: Contribution to journal › Article

Conformations

Agglomeration

Sampling

Temperature

Proteins

2014

22 Citations (Scopus)

Construction of a live-attenuated HIV-1 vaccine through genetic code expansion

Wang, N., Li, Y., Niu, W., Sun, M., Cerny, R., Li, Q. & Guo, J., May 5 2014, In : Angewandte Chemie - International Edition. 53, 19, p. 4867-4871 5 p.

Research output: Contribution to journal › Article

Vaccines

Viruses

Attenuated Vaccines

Biosynthesis

Amino acids

43 Citations (Scopus)

Iterative assembly of two separate polyketide chains by the same single-module bacterial polyketide synthase in the biosynthesis of HSAF

Li, Y., Chen, H., Ding, Y., Xie, Y., Wang, H., Cerny, R., Shen, Y. & Du, L., Jul 14 2014, In : Angewandte Chemie - International Edition. 53, 29, p. 7524-7530 7 p.

Research output: Contribution to journal › Article

Polyketide Synthases

Polyketides

Polyenes

Biosynthesis

Peptide Synthases

2013

41 Citations (Scopus)

Development of affinity microcolumns for drug-protein binding studies in personalized medicine: Interactions of sulfonylurea drugs with in vivo glycated human serum albumin

Anguizola, J., Joseph, K. S., Barnaby, O. S., Matsuda, R., Alvarado, G., Clarke, W., Cerny, R. & Hage, D. S., May 7 2013, In : Analytical chemistry. 85, 9, p. 4453-4460 8 p.

Research output: Contribution to journal › Article

Serum Albumin

Medicine

Pharmaceutical Preparations

Medical problems

Proteins

8 Citations (Scopus)

Molecular recognition of sulfotyrosine and phosphotyrosine by the Src homology 2 domain

Ju, T., Niu, W., Cerny, R., Bollman, J., Roy, A. & Guo, J., Jul 2013, In : Molecular BioSystems. 9, 7, p. 1829-1832 4 p.

Research output: Contribution to journal › Article

Phosphotyrosine

src Homology Domains

Protein Engineering

Post Translational Protein Processing

tyrosine O-sulfate

17 Citations (Scopus)

Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids

Melton, E. M., Cerny, R., DiRusso, C. C. & Black, P. N., Nov 1 2013, In : Biochemical and Biophysical Research Communications. 440, 4, p. 743-748 6 p.

Research output: Contribution to journal › Article

Fatty Acid Transport Proteins

Fatty Acids

Coenzyme A

Phosphatidic Acids

Phosphatidylinositols

6 Citations (Scopus)

Tricarballylic ester formation during biosynthesis of fumonisin mycotoxins in Fusarium verticillioides

Li, Y., Lou, L., Cerny, R., Butchko, R. A. E., Proctor, R. H., Shen, Y. & Du, L., Dec 1 2013, In : Mycology. 4, 4, p. 179-186 8 p.

Research output: Contribution to journal › Article

Fumonisins

Mycotoxins

fumonisins

Fusarium

Esters

2012

3 Citations (Scopus)

An in vitro system to study cyclopeptide heterophyllin B biosynthesis in the medicinal plant Pseudostellaria heterophylla

Xu, W., Zhu, H., Tan, N., Tang, J., Zhang, Y., Cerny, R. & Du, L., Jan 1 2012, In : Plant Cell, Tissue and Organ Culture. 108, 1, p. 137-145 9 p.

Research output: Contribution to journal › Article

medicinal plants

biosynthesis

shoots

cysteamine

proline

14 Citations (Scopus)

Knockdown of the cellular protein lrpprc attenuates HIV-1 infection

Schweitzer, C. J., Matthews, J. M., Madson, C. J., Donnellan, M. R., Cerny, R. & Belshan, M., Jul 12 2012, In : PloS one. 7, 7, e40537.

Research output: Contribution to journal › Article

Human immunodeficiency virus 1

Leucine

leucine

HIV Infections

HIV-1

36 Citations (Scopus)

Paramecium bursaria chlorella virus 1 proteome reveals novel architectural and regulatory features of a giant virus

Dunigan, D. D., Cerny, R., Bauman, A. T., Roach, J. C., Lane, L. C., Agarkova, I. V., Wulser, K., Yanai-Balser, G. M., Gurnon, J. R., Vitek, J. C., Kronschnabel, B. J., Jeanniard, A., Blanc, G., Upton, C., Duncan, G. A., McClung, O. W., Ma, F. & Van Etten, J. L., Aug 1 2012, In : Journal of virology. 86, 16, p. 8821-8834 14 p.

Research output: Contribution to journal › Article

Paramecium bursaria Chlorella virus 1

Paramecium

Chlorella

Proteome

proteome

4 Citations (Scopus)

The applicability of molecular descriptors for designing an electrospray ionization mass spectrometry compatible library for drug discovery

Copeland, J. C., Zehr, L. J., Cerny, R. & Powers, R., Dec 1 2012, In : Combinatorial Chemistry and High Throughput Screening. 15, 10, p. 806-815 10 p.

Research output: Contribution to journal › Article

Electrospray ionization

Electrospray Ionization Mass Spectrometry

Drug Discovery

Libraries

Mass spectrometry

12 Citations (Scopus)

The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A

Moghe, S., Jiang, F., Miura, Y., Cerny, R., Tsai, M. Y. & Furukawa, M., Feb 15 2012, In : Biology Open. 1, 2, p. 82-91 10 p.

Research output: Contribution to journal › Article

Ligases

ligases

Ubiquitination

Mitosis

mitosis

30 Citations (Scopus)

Unusual activities of the thioesterase domain for the biosynthesis of the polycyclic tetramate macrolactam HSAF in lysobacter enzymogenes C3

Lou, L., Chen, H., Cerny, R., Li, Y., Shen, Y. & Du, L., Jan 10 2012, In : Biochemistry. 51, 1, p. 4-6 3 p.

Research output: Contribution to journal › Article

Lysobacter

Mutagenesis

Biosynthesis

Ligases

Multigene Family

2011

5 Citations (Scopus)

A cytoplasm-specific activity encoded by the Trithorax-like ATX1 gene

Ndamukong, I., Lapko, H., Cerny, R. & Avramova, Z. V., Jun 1 2011, In : Nucleic acids research. 39, 11, p. 4709-4718 10 p.

Research output: Contribution to journal › Article

Histones

Protein Isoforms

Cytoplasm

Modifier Genes

Arabidopsis Proteins

97 Citations (Scopus)

Comparison of modification sites formed on human serum albumin at various stages of glycation

Barnaby, O. S., Cerny, R., Clarke, W. & Hage, D. S., Jan 30 2011, In : Clinica Chimica Acta. 412, 3-4, p. 277-285 9 p.

Research output: Contribution to journal › Article

Serum Albumin

Medical problems

Lysine

Arginine

Glucose

25 Citations (Scopus)

Human fatty acid transport protein 2a/very long chain Acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol

Melton, E. M., Cerny, R., Watkins, P. A., DiRusso, C. C. & Black, P. N., Sep 2 2011, In : Journal of Biological Chemistry. 286, 35, p. 30670-30679 10 p.

Research output: Contribution to journal › Article

Fatty Acid Transport Proteins

Omega-3 Fatty Acids

Phosphatidylinositols

Fatty Acids

Chemical activation

52 Citations (Scopus)

Overexpression of GalNAc-transferase GalNAc-T3 promotes pancreatic cancer cell growth

Taniuchi, K., Cerny, R., Tanouchi, A., Kohno, K., Kotani, N., Honke, K., Saibara, T. & Hollingsworth, M. A., Dec 8 2011, In : Oncogene. 30, 49, p. 4843-4854 12 p.

Research output: Contribution to journal › Article

Pancreatic Neoplasms

Glycosylation

Growth

Transferases

Peptides

44 Citations (Scopus)

Quantitative analysis of glycation patterns in human serum albumin using ¹⁶O/¹⁸O-labeling and MALDI-TOF MS

Barnaby, O. S., Cerny, R., Clarke, W. & Hage, D. S., Aug 17 2011, In : Clinica Chimica Acta. 412, 17-18, p. 1606-1615 10 p.

Research output: Contribution to journal › Article

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

Serum Albumin

Labeling

Chemical analysis

Pharmaceutical Preparations

63 Citations (Scopus)

Structure function analysis of an ADP-ribosyltransferase type III effector and its RNA-binding target in plant immunity

Jeong, B. R., Lin, Y., Joe, A., Guo, M., Korneli, C., Yang, H., Wang, P., Yu, M., Cerny, R., Staiger, D., Alfano, J. R. & Xu, Y., Dec 16 2011, In : Journal of Biological Chemistry. 286, 50, p. 43272-43281 10 p.

Research output: Contribution to journal › Article

Plant Immunity

ADP Ribose Transferases

RNA-Binding Proteins

Plant Cells

RNA

4 Citations (Scopus)

Transformation of Fusarium verticillioides with a polyketide gene cluster isolated from a fungal endophyte activates the biosynthesis of fusaric acid

Xie, Y., Zhang, W., Li, Y., Wang, M., Cerny, R., Shen, Y. & Du, L., Mar 1 2011, In : Mycology. 2, 1, p. 24-29 6 p.

Research output: Contribution to journal › Article

Fusaric Acid

fusaric acid

Endophytes

Polyketides

polyketides

2010

25 Citations (Scopus)

Characterization of surface-exposed reactive cysteine residues in saccharomyces cerevisiae

Marino, S. M., Li, Y., Fomenko, D., Agisheva, N., Cerny, R. & Gladyshev, V. N., Sep 7 2010, In : Biochemistry. 49, 35, p. 7709-7721 13 p.

Research output: Contribution to journal › Article

Yeast

Cysteine

Saccharomyces cerevisiae

Sulfhydryl Compounds

Oxidation-Reduction

25 Citations (Scopus)

Fluoride-promoted ligand exchange in diaryliodonium salts

Wang, B., Cerny, R., Uppaluri, S., Kempinger, J. J. & Dimagno, S. G., Nov 1 2010, In : Journal of Fluorine Chemistry. 131, 11, p. 1113-1121 9 p.

Research output: Contribution to journal › Article

Fluorides

fluoride

ligand

fluorides

Salts

39 Citations (Scopus)

High throughput quantification of N-glycans using one-pot sialic acid modification and matrix assisted laser desorption ionization time-of-flight mass spectrometry

Gil, G. C., Iliff, B., Cerny, R., Velander, W. H. & Cott, K. E. V., Aug 1 2010, In : Analytical chemistry. 82, 15, p. 6613-6620 8 p.

Research output: Contribution to journal › Article

N-Acetylneuraminic Acid

Ionization

Mass spectrometry

Polysaccharides

Desorption

43 Citations (Scopus)

Improved arene fluorination methodology for I(III) salts

Wang, B., Qin, L., Neumann, K. D., Uppaluri, S., Cerny, R. & DiMagno, S. G., Aug 6 2010, In : Organic Letters. 12, 15, p. 3352-3355 4 p.

Research output: Contribution to journal › Article

Fluorination

fluorination

Halogenation

Salts

methodology

66 Citations (Scopus)

Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas

Shaver, S., Casas-Mollano, J. A., Cerny, R. & Cerutti, H. D., May 16 2010, In : Epigenetics. 5, 4, p. 301-312 12 p.

Research output: Contribution to journal › Article

Polycomb Repressive Complex 2

Chlamydomonas

Gene Silencing

Eukaryota

Histones

21 Citations (Scopus)

Proteomic analysis of atrazine exposure in Drosophila melanogaster (Diptera: Drosophilidae)

Thornton, B. J., Elthon, T. E., Cerny, R. & Siegfried, B. D., Sep 1 2010, In : Chemosphere. 81, 2, p. 235-241 7 p.

Research output: Contribution to journal › Article

Drosophilidae

Atrazine

proteomics

Herbicides

atrazine

38 Citations (Scopus)

Quantitative analysis of glycation sites on human serum albumin using ¹⁶O/¹⁸O-labeling and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Barnaby, O. S., Wa, C., Cerny, R., Clarke, W. & Hage, D. S., Aug 1 2010, In : Clinica Chimica Acta. 411, 1-16, p. 1102-1110 9 p.

Research output: Contribution to journal › Article

Serum Albumin

Labeling

Ionization

Mass spectrometry

Desorption

2009

21 Citations (Scopus)

Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels

Wei, Q., Galbenus, R., Raza, A., Cerny, R. & Simpson, M. A., Mar 15 2009, In : Cancer Research. 69, 6, p. 2332-2339 8 p.

Research output: Contribution to journal › Article

Uridine Diphosphate Glucose Dehydrogenase

Hyaluronic Acid

Androgens

Prostate

Dihydrotestosterone

1 Citation (Scopus)

Expression artifact with retroviral vectors based on pBMN

Fukunaga, Y., Svoboda, R. A., Cerny, R., Johnson, K. R. & Wheelock, M. J., Dec 1 2009, In : Analytical Biochemistry. 395, 1, p. 49-53 5 p.

Research output: Contribution to journal › Article

Artifacts

Molecular Weight

Molecular weight

Post Translational Protein Processing

Fusion reactions

28 Citations (Scopus)

Protein-protein interactions of tandem affinity purified protein kinases from rice

Rohila, J. S., Chen, M., Chen, S., Chen, J., Cerny, R., Dardick, C., Canlas, P., Fujii, H., Gribskov, M., Kanrar, S., Knoflicek, L., Stevenson, B., Xie, M., Xu, X., Zheng, X., Zhu, J. K., Ronald, P. & Fromm, M. E., Aug 19 2009, In : PloS one. 4, 8, e6685.

Research output: Contribution to journal › Article

protein-protein interactions

protein kinases

rice protein

Protein Kinases

rice

2008

2 Citations (Scopus)

Identification of guanylate cyclases and related signaling proteins in sperm tail from sea stars by mass spectrometry

Nakachi, M., Matsumoto, M., Terry, P. M., Cerny, R. & Moriyama, H., Sep 1 2008, In : Marine Biotechnology. 10, 5, p. 564-571 8 p.

Research output: Contribution to journal › Article

Starfish

Sperm Tail

guanylate cyclase

Guanylate Cyclase

Asteroidea

138 Citations (Scopus)

Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease

Reynolds, A. D., Glanzer, J. G., Kadiu, I., Ricardo-Dukelow, M., Chaudhuri, A., Ciborowski, P. S., Cerny, R., Gelman, B., Thomas, M. P., Mosley, R. L. & Gendelman, H. E., Mar 1 2008, In : Journal of Neurochemistry. 104, 6, p. 1504-1525 22 p.

Research output: Contribution to journal › Article

alpha-Synuclein

Microglia

Parkinson Disease

NF-kappa B

Proteome

145 Citations (Scopus)

Phosphorylation of claudin-5 and occludin by Rho kinase in brain endothelial cells

Yamamoto, M., Ramirez, S. H., Sato, S., Kiyota, T., Cerny, R., Kaibuchi, K., Persidsky, Y. & Ikezu, T., Feb 2008, In : American Journal of Pathology. 172, 2, p. 521-533 13 p.

Research output: Contribution to journal › Article

Claudin-5

Occludin

rho-Associated Kinases

Endothelial Cells

Phosphorylation

66 Citations (Scopus)

Phosphorylation of MUC1 by met modulates interaction with p53 and MMP1 expression

Singh, P., Behrens, M. E., Eggers, J. P., Cerny, R., Bailey, J. M., Shanmugam, K., Gendler, S. J., Bennett, E. P. & Hollingsworth, M. A., Oct 3 2008, In : Journal of Biological Chemistry. 283, 40, p. 26985-26995 11 p.

Research output: Contribution to journal › Article

Phosphorylation

Hepatocyte Growth Factor

Receptor Protein-Tyrosine Kinases

Mucins

Transcription

2007

240 Citations (Scopus)

A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity

Fu, Z. Q., Guo, M., Jeong, B. R., Tian, F., Elthon, T. E., Cerny, R., Staiger, D. & Alfano, J. R., May 17 2007, In : Nature. 447, 7142, p. 284-288 5 p.

Research output: Contribution to journal › Article

Plant Immunity

Pseudomonas syringae

RNA-Binding Proteins

ADP Ribose Transferases

Adenosine Diphosphate

95 Citations (Scopus)

Characterization of glycation adducts on human serum albumin by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Wa, C., Cerny, R., Clarke, W. A. & Hage, D. S., Oct 1 2007, In : Clinica Chimica Acta. 385, 1-2, p. 48-60 13 p.

Research output: Contribution to journal › Article

Serum Albumin

Ionization

Mass spectrometry

Desorption

Mass Spectrometry

85 Citations (Scopus)

Platelet-derived growth factor receptor β-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells

Singh, P., Wen, Y., Swanson, B. J., Shanmugam, K., Kazlauskas, A., Cerny, R., Gendler, S. J. & Hollingsworth, M. A., Jun 1 2007, In : Cancer Research. 67, 11, p. 5201-5210 10 p.

Research output: Contribution to journal › Article

Platelet-Derived Growth Factor Receptors

Adenocarcinoma

Phosphorylation

Tail

Tyrosine

135 Citations (Scopus)

SelT, SelW, SelH, and Rdx 12: Genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family

Dikiy, A., Novoselov, S. V., Fomenko, D., Sengupta, A., Carlson, B. A., Cerny, R., Ginalski, K., Grishin, N. V., Hatfield, D. L. & Gladyshev, V. N., Jun 12 2007, In : Biochemistry. 46, 23, p. 6871-6882 12 p.

Research output: Contribution to journal › Article

Selenoproteins

Thioredoxins

Genomics

Selenocysteine

Proteins

2006

33 Citations (Scopus)

Global characterization of porcine intrauterine proteins during early pregnancy

Kayser, J. P. R., Kim, J. G., Cerny, R. & Vallet, J. L., Feb 1 2006, In : Reproduction. 131, 2, p. 379-388 10 p.

Research output: Contribution to journal › Article

Swine

Pregnancy

Proteins

Gels

Glycocalyx

24 Citations (Scopus)

Identification and quantitative studies of protein immobilization sites by stable isotope labeling and mass spectrometry

Wa, C., Cerny, R. & Hage, D. S., Dec 1 2006, In : Analytical chemistry. 78, 23, p. 7967-7977 11 p.

Research output: Contribution to journal › Article

Serum Albumin

Isotopes

Labeling

Mass spectrometry

Proteins