Robert E Lewis, PhD

Professor

  • 2515 Citations
  • 29 h-Index
1980 …2021
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Phosphorylation Chemical Compounds
Insulin Receptor Medicine & Life Sciences
Extracellular Signal-Regulated MAP Kinases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
AMP-Activated Protein Kinases Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Serine Medicine & Life Sciences
Bradykinin Medicine & Life Sciences

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Projects 1984 2021

LABORATORY CANCER RESEARCH CENTER

Cerny, R., Issenberg, P., Bresnick, E., Kuszynski, C. A., Christman, J., Lynch, J. C., Tempero, M., Nagel, D., Smith, D. L., Kuszynski, C. A., Pour, P., Vose, J. M., Hollingsworth, T., Rogan, E. G., Bridge, J. A., Sherman, S., Lawson, T. A., Johnson, D. R., Kessinger, M. A., Cowan, K. H., Hollingsworth, T., Rogan, E. G., Bridge, J. A., Volsky, D., Conrad, R., Nagel, D., Rhode, S., Ruddon, R., Ramspott, E., Pour, P., Gmeiner, W., Lewis, R. E., Borgstahl, G. E., Caplan, S. H., Band, H., Ganti, A. K. P., Meza, J. L., Black, J. D., Guda, B., Wang, J., Semerad, C. L. & Wang, G.

National Institutes of Health

7/1/847/31/21

Project: Research project

Neoplasms
Research
Tissue and Organ Procurement
Molecular Biology
Research Personnel
Colon
Carcinogenesis
Neoplasms
ras Proteins
Maintenance

Nebraska Center for Cellular Signaling

Johnson, K. R., Simpson, M. A., Wahl, J. K., Caplan, S. H., Nawshad, A., Luo, X., Oakley, G. G., Furukawa, M., Wang, J., Lewis, R. E., Caplan, S. H., Naslavsky, N., Dong, J., Opavsky, R., Wahl, J. K., Solheim, J. C., Peng, A., Luo, X., Simpson, M. A., Wheelock, M., Koka, S., Dey, B., Hansen, L., Gladyshev, V. N., Nawaz, Z., Yaping, T., Wang, Z., Premaraj, S., Taylor, G. S., Tsai, M. & Mehta, P. P.

National Institutes of Health

9/19/036/30/13

Project: Research project

funding
school
infrastructure
grant
dentistry

Research Output 1980 2019

  • 2515 Citations
  • 29 h-Index
  • 74 Article
  • 2 Review article
  • 1 Comment/debate

ERK-mediated TIMELESS expression suppresses G2/M arrest in colon cancer cells

Neilsen, B. K., Frodyma, D. E., McCall, J. L., Fisher, K. W. & Lewis, R. E., Jan 1 2019, In : PLoS One. 14, 1, e0209224.

Research output: Contribution to journalArticle

colorectal neoplasms
Colonic Neoplasms
Cell proliferation
Cells
cell proliferation
4 Citations (Scopus)

A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells

Das, B., Neilsen, B. K., Fisher, K. W., Gehring, D., Hu, Y., Volle, D. J., Kim, H. S., McCall, J. L., Kelly, D. L., MacMillan, J. B., White, M. A. & Lewis, R. E., Dec 1 2018, In : Scientific Reports. 8, 1, 3770.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Colonic Neoplasms
Colon
Neoplasms
Cell Line

Correction: KSR1 is required for cell cycle reinitiation following DNA damage.(Journal of Biological Chemistry (2018)284 (6705– 6715))

Razidlo, G. L., Johnson, H. J., Stoeger, S. M., Cowan, K. H., Bessho, T. & Lewis, R. E., Jan 1 2018, In : Journal of Biological Chemistry. 293, 49, 1 p.

Research output: Contribution to journalComment/debate

DNA Damage
Cell Cycle
Cells
DNA

The miR-17~92 cluster activates mTORC1 in mantle cell lymphoma by targeting multiple regulators in the STK11/AMPK/TSC/mTOR pathway

Jiang, C., Bi, C., Jiang, X., Tian, T., Huang, X., Wang, C., Fernandez, M. R., Iqbal, J., Chan, W. C., McKeithan, T. W., Lewis, R. E. & Fu, K., Jan 1 2018, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
AMP-Activated Protein Kinases
mechanistic target of rapamycin complex 1
1 Citation (Scopus)

WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage

Neilsen, B. K., Chakraborty, B., McCall, J. L., Frodyma, D. E., Sleightholm, R. L., Fisher, K. W. & Lewis, R. E., Jun 20 2018, In : BMC Cancer. 18, 1, 673.

Research output: Contribution to journalArticle

Colonic Neoplasms
Methylation
DNA Damage
Cell Line
Neoplasms