Richard M Tempero, MD, PhD

Director

  • 665 Citations
  • 14 h-Index
19962017
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1996 2016

  • 665 Citations
  • 14 h-Index
  • 25 Article
Filter
Article
2016

Invariant asymmetry renews the lymphatic vasculature during homeostasis

Connor, A. L., Kelley, P. M. & Tempero, R. M., Jul 11 2016, In : Journal of Translational Medicine. 14, 1, 209.

Research output: Contribution to journalArticle

Endothelial cells
Lycopersicon esculentum
Lymphatic Vessels
Homeostasis
Dimers
6 Citations (Scopus)

Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis

Connor, A. L., Kelley, P. M. & Tempero, R. M., Mar 1 2016, In : Laboratory Investigation. 96, 3, p. 270-282 13 p.

Research output: Contribution to journalArticle

Lymphangiogenesis
Lymphatic Vessels
Endothelial Cells
Lycopersicon esculentum
Sutures
2014
11 Citations (Scopus)

Nerve growth factor regulates neurolymphatic remodeling during corneal inflammation and resolution

Fink, D. M., Connor, A. L., Kelley, P. M., Steele, M. M., Hollingsworth, M. A. & Tempero, R. M., Nov 10 2014, In : PloS one. 9, 11, e112737.

Research output: Contribution to journalArticle

nerve growth factor
Nerve Growth Factor
inflammation
Lymphangiogenesis
Inflammation
2013
18 Citations (Scopus)

Lymphatic vessel memory stimulated by recurrent inflammation

Kelley, P. M., Connor, A. L. & Tempero, R. M., Jun 1 2013, In : American Journal of Pathology. 182, 6, p. 2418-2428 11 p.

Research output: Contribution to journalArticle

Lymphatic Vessels
Inflammation
Lymphangiogenesis
Vascular Endothelial Growth Factor C
Macrophages
2011
6 Citations (Scopus)

Glucocorticoids suppress corneal lymphangiogenesis

Steele, M. M., Kelley, P. M., Schieler, A. M. & Tempero, R. M., Dec 1 2011, In : Cornea. 30, 12, p. 1442-1447 6 p.

Research output: Contribution to journalArticle

Lymphangiogenesis
Lymphatic Vessels
Glucocorticoids
Dexamethasone
Sutures
9 Citations (Scopus)

Regressed lymphatic vessels develop during corneal repair

Kelley, P. M., Steele, M. M. & Tempero, R. M., Nov 1 2011, In : Laboratory Investigation. 91, 11, p. 1643-1651 9 p.

Research output: Contribution to journalArticle

Lymphatic Vessels
Sutures
Inflammation
Cornea
Leukocytes
6 Citations (Scopus)

β1 integrin regulates MMP-10 dependant tubulogenesis in human lymphatic endothelial cells

Steele, M. M., Schieler, A. M., Kelley, P. M. & Tempero, R. M., Apr 1 2011, In : Matrix Biology. 30, 3, p. 218-224 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 10
Matrix Metalloproteinases
Integrins
Lymphatic Vessels
Endothelial Cells
2010
61 Citations (Scopus)

Lymphatic malformations: Current cellular and clinical investigations

Perkins, J. A., Manning, S. C., Tempero, R. M., Cunningham, M. J., Edmonds, J. L., Hoffer, F. A. & Egbert, M. A., Jun 1 2010, In : Otolaryngology - Head and Neck Surgery. 142, 6, p. 789-794 6 p.

Research output: Contribution to journalArticle

Neck
Head
Outcome Assessment (Health Care)
Stromal Cells
Endothelial Cells
120 Citations (Scopus)

Lymphatic malformations: Review of current treatment

Perkins, J. A., Manning, S. C., Tempero, R. M., Cunningham, M. J., Edmonds, J. L., Hoffer, F. A. & Egbert, M. A., Jun 2010, In : Otolaryngology - Head and Neck Surgery. 142, 6, p. 795-803.e1

Research output: Contribution to journalArticle

Sclerotherapy
Therapeutics
Tooth
Macroglossia
Malocclusion
5 Citations (Scopus)

Lymphatic vessel hypertrophy in inflamed human tonsils

Kelley, P. M. & Tempero, R. M., Jun 1 2010, In : Lymphatic Research and Biology. 8, 2, p. 121-126 6 p.

Research output: Contribution to journalArticle

Lymphatic Vessels
Palatine Tonsil
Hypertrophy
Lymphatic System
Germinal Center
2008
25 Citations (Scopus)

Integrin α1β1 regulates matrix metalloproteinases via p38 mitogen-activated protein kinase in mesangial cells: Implications for alport syndrome

Cosgrove, D. E., Meehan, D. T., Delimont, D., Pozzi, A., Chen, X., Rodgers, K. D., Tempero, R. M., Zallocchi, M. L. & Rao, V. H., Mar 2008, In : American Journal of Pathology. 172, 3, p. 761-773 13 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 11
Hereditary Nephritis
Mesangial Cells
p38 Mitogen-Activated Protein Kinases
Integrins
2007
19 Citations (Scopus)

Clinical outcomes in lymphocytopenic lymphatic malformation patients

Perkins, J. A., Tempero, R. M., Hannibal, M. C. & Manning, S. C., Nov 1 2007, In : Lymphatic Research and Biology. 5, 3, p. 169-173 5 p.

Research output: Contribution to journalArticle

Lymphopenia
Anti-Bacterial Agents
Infection
Hospitalization
Pediatric Hospitals
2006
23 Citations (Scopus)

Lymphocytopenia in children with lymphatic malformation

Tempero, R. M., Hannibal, M., Finn, L. S., Manning, S. C., Cunningham, M. L. & Perkins, J. A., Jan 1 2006, In : Archives of Otolaryngology - Head and Neck Surgery. 132, 1, p. 93-97 5 p.

Research output: Contribution to journalArticle

Lymphopenia
Blood Cell Count
Lymphocyte Subsets
Lymphocytes
Natural Killer T-Cells
2004
14 Citations (Scopus)

Proliferation and differentiation of CD8+ T cells in the absence of IL-2/15 receptor β-chain expression or STAT5 activation

Teague, R. M., Tempero, R. M., Thomas, S., Murali-Krishna, K. & Nelson, B. H., Sep 1 2004, In : Journal of Immunology. 173, 5, p. 3131-3139 9 p.

Research output: Contribution to journalArticle

Interleukin-15 Receptors
Interleukin-2 Receptors
T-Lymphocytes
Interleukin-2
Interleukin-15
2002
15 Citations (Scopus)

Molecular requirements for CD8-mediated rejection of a MUC1-expressing pancreatic carcinoma: Implications for tumor vaccines

Sivinski, C. L., Kohlgraf, K. G., VanLith, M. L., Morikane, K., Tempero, R. M. & Hollingsworth, M. A., Jul 18 2002, In : Cancer Immunology, Immunotherapy. 51, 6, p. 327-340 14 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Neoplasms
Immunity
Pancreatic Carcinoma
Cytokines
16 Citations (Scopus)

MUC1-specific anti-tumor responses: Molecular requirements for CD4-mediated responses

VanLith, M. L., Kohlgraf, K. G., Sivinski, C. L., Tempero, R. M. & Hollingsworth, M. A., Aug 29 2002, In : International Immunology. 14, 8, p. 873-882 10 p.

Research output: Contribution to journalArticle

Neoplasm Antigens
T-Lymphocytes
Natural Killer Cells
Neoplasms
Lymphotoxin-alpha
2001
16 Citations (Scopus)

Influence of organ site and tumor cell type on MUC1-specific tumor immunity

Morikane, K., Tempero, R. M., Sivinski, C. L., Kitajima, S., Gendler, S. J. & Hollingsworth, M. A., Jan 1 2001, In : International Immunology. 13, 2, p. 233-240 8 p.

Research output: Contribution to journalArticle

Open Access
Immunity
Pancreas
Neoplasms
Adoptive Transfer
Pancreatic Neoplasms
1999
16 Citations (Scopus)

Organ-specific pancreatic tumor growth properties and tumor immunity

Morikane, K., Tempero, R. M., Sivinski, C. L., Nomoto, M., Van Lith, M. L., Muto, T. & Hollingsworth, M. A., Feb 9 1999, In : Cancer Immunology Immunotherapy. 47, 5, p. 287-296 10 p.

Research output: Contribution to journalArticle

Immunity
Growth
Neoplasms
Pancreas
Immunoglobulin M
19 Citations (Scopus)
Transgenic Mice
Anti-Idiotypic Antibodies
Immunity
Tandem Repeat Sequences
Immunoglobulin G
1998
56 Citations (Scopus)

CD4+ lymphocytes provide MUC1-specific tumor immunity in vivo that is undetectable in vitro and is absent in MUC1 transgenic mice

Tempero, R. M., VanLith, M. L., Morikane, K., Rowse, G. J., Gendler, S. J. & Hollingsworth, M. A., Nov 15 1998, In : Journal of Immunology. 161, 10, p. 5500-5506 7 p.

Research output: Contribution to journalArticle

Transgenic Mice
Immunity
Lymphocytes
Neoplasms
Adoptive Transfer

In vitro kinetic analysis of cellular anti-MUC1 immune responses in MUC1 transgenic mice

VanLith, M. L., Tempero, R. M., Gendler, S. J. & Hollingsworth, M. A., Mar 20 1998, In : FASEB Journal. 12, 5, p. A891

Research output: Contribution to journalArticle

Transgenic Mice
Tumors
immune response
genetically modified organisms
kinetics

Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model

Tempero, R. M., Morikane, K., Vanlith, M. L., Gendler, S. J. & Hollingsworth, M. A., Mar 20 1998, In : FASEB Journal. 12, 5, p. A891

Research output: Contribution to journalArticle

Tumors
Immunity
immunity
animal models
genetically modified organisms
168 Citations (Scopus)

Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model

Rowse, G. J., Tempero, R. M., VanLith, M. L., Hollingsworth, M. A. & Gendler, S. J., Jan 15 1998, In : Cancer Research. 58, 2, p. 315-321 7 p.

Research output: Contribution to journalArticle

Transgenic Mice
Immunity
Neoplasms
Immunotherapy
Immunoglobulin Class Switching
1997
36 Citations (Scopus)

Molecular Adjuvant Effects of a Conformationally Biased Agonist of Human C5a Anaphylatoxin

Tempero, R. M., Hollingsworth, M. A., Burdick, M. D., Finch, A. M., Taylor, S. M., Vogen, S. M., Morgan, E. L. & Sanderson, S. D., Feb 1 1997, In : Journal of Immunology. 158, 3, p. 1377-1382 6 p.

Research output: Contribution to journalArticle

Anaphylatoxins
Epitopes
Opioid Receptors
Opioid Analgesics
1996
agonists
Antibody Formation
Vaccines
peptides
vaccines