Prabagaran Narayanasamy, PhD

Assistant Professor

  • 1530 Citations
  • 17 h-Index
20012019
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Research Output 2001 2019

  • 1530 Citations
  • 17 h-Index
  • 37 Article
  • 1 Comment/debate
  • 1 Short survey
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Article
2019
gallium nitrate
Gallium
Porphyrins
Klebsiella pneumoniae
Pseudomonas aeruginosa
2 Citations (Scopus)
Acinetobacter baumannii
Gallium
Heme
Nanoparticles
Pseudomonas aeruginosa

Novel MenA inhibitors are bactericidal against mycobacterium tuberculosis and synergize with electron transport chain inhibitors

Berube, B. J., Russell, D., Castro, L., Choi, S. R., Narayanasamy, P. & Parish, T., Jun 2019, In : Antimicrobial Agents and Chemotherapy. 63, 6, e02661-18.

Research output: Contribution to journalArticle

Open Access
Electron Transport
Mycobacterium tuberculosis
Vitamin K 2
Pharmaceutical Preparations
bedaquiline
1 Citation (Scopus)
Open Access
Gallium
Mycobacterium tuberculosis
Nanoparticles
HIV-1
Macrophages
2018
3 Citations (Scopus)
Mycobacterium avium
Gallium
Mycobacterium
Nanoparticles
Growth
2017
7 Citations (Scopus)
Flavonoids
Pyruvaldehyde
Neurons
Neurodegenerative Diseases
Poisons
9 Citations (Scopus)
Virus Release
Gallium
Interleukin-8
Mycobacterium tuberculosis
Nanoparticles
14 Citations (Scopus)

Gallium nanoparticles facilitate phagosome maturation and inhibit growth of virulent Mycobacterium tuberculosis in macrophages

Choi, S. R., Britigan, B. E., Moran, D. M. & Narayanasamy, P., May 2017, In : PloS one. 12, 5, e0177987.

Research output: Contribution to journalArticle

gallium
phagosomes
Phagosomes
Gallium
Macrophages
8 Citations (Scopus)

Novel long-chain compounds with both immunomodulatory and MenA inhibitory activities against Staphylococcus aureus and its biofilm

Choi, S. R., Frandsen, J. & Narayanasamy, P., Jan 10 2017, In : Scientific reports. 7, 40077.

Research output: Contribution to journalArticle

Methicillin-Resistant Staphylococcus aureus
Biofilms
Staphylococcus aureus
Vitamin K 2
Interleukin-6
2016
7 Citations (Scopus)
DNA Primase
Amines
Bacillus anthracis
Tilorone
Microbial Sensitivity Tests
13 Citations (Scopus)

Discovery of bicyclic inhibitors against menaquinone biosynthesis

Choi, S. R., Larson, M. A., Hinrichs, S. H., Bartling, A. M., Frandsen, J. & Narayanasamy, P., Jan 2016, In : Future Medicinal Chemistry. 8, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle

Vitamin K 2
Methicillin-Resistant Staphylococcus aureus
Mycobacterium tuberculosis
Gram-Positive Bacteria
Electron Transport
2015
2 Citations (Scopus)

Potential of N-acetylated-para-aminosalicylic acid to accelerate manganese enhancement decline for long-term MEMRI in rodent brain

Bade, A. N., Zhou, B., McMillan, J. M., Narayanasamy, P., Veerubhotla, R., Gendelman, H. E., Boska, M. D. & Liu, Y., Aug 5 2015, In : Journal of Neuroscience Methods. 251, p. 92-98 7 p.

Research output: Contribution to journalArticle

Aminosalicylic Acid
Manganese
Rodentia
Brain
Animal Diseases
24 Citations (Scopus)
Gallium
Mycobacterium
Nanoparticles
Macrophages
HIV
2014
22 Citations (Scopus)

Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes

Edagwa, B. J., Guo, D., Puligujja, P., Chen, H., McMillan, J. M., Liu, X., Gendelman, H. E. & Narayanasamy, P., Dec 1 2014, In : FASEB Journal. 28, 12, p. 5071-5082 12 p.

Research output: Contribution to journalArticle

Macrophages
Endosomes
Rifampin
Nanoparticles
Derivatives
2013
18 Citations (Scopus)

Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection

Epstein, A. A., Narayanasamy, P., Dash, P. K., High, R., Bathena, S. P. R., Gorantla, S., Poluektova, L. Y., Alnouti, Y., Gendelman, H. E. & Boska, M. D., Dec 1 2013, In : Journal of Neuroimmune Pharmacology. 8, 5, p. 1224-1238 15 p.

Research output: Contribution to journalArticle

Metabolomics
Virus Diseases
Tissue Preservation
HIV-1
Rodentia
10 Citations (Scopus)
Azides
Bacteria
Derivatives
Staphylococcus aureus
Burkholderia mallei
2012
105 Citations (Scopus)

Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages

Kadiu, I., Narayanasamy, P., Dash, P. K., Zhang, W. & Gendelman, H. E., Jul 15 2012, In : Journal of Immunology. 189, 2, p. 744-754 11 p.

Research output: Contribution to journalArticle

Exosomes
HIV Infections
HIV-1
Macrophages
Virus Diseases
2010
56 Citations (Scopus)

DosS responds to a reduced electron transport system to induce the mycobacterium tuberculosis DosR regulon

Honaker, R. W., Dhiman, R. K., Narayanasamy, P., Crick, D. C. & Voskuil, M. I., Dec 1 2010, In : Journal of bacteriology. 192, 24, p. 6447-6455 9 p.

Research output: Contribution to journalArticle

Vitamin K 2
Regulon
Electron Transport
Mycobacterium tuberculosis
Oxygen
13 Citations (Scopus)

Synthesis of 4-Diphosphocytidyl-2-C-Methyl-D-Erythritol 2-Phosphate and Kinetic Studies of Mycobacterium tuberculosis IspF

Narayanasamy, P., Eoh, H., Brennan, P. J. & Crick, D. C., Feb 26 2010, In : Chemistry and Biology. 17, 2, p. 117-122 6 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Cytidine Monophosphate
Cytidine
Kinetics
Arabinose
2009
17 Citations (Scopus)

Expression and Characterization of Soluble 4-Diphosphocytidyl-2-C-methyl-D-erythritol Kinase from Bacterial Pathogens

Eoh, H., Narayanasamy, P., Brown, A. C., Parish, T., Brennan, P. J. & Crick, D. C., Dec 24 2009, In : Chemistry and Biology. 16, 12, p. 1230-1239 10 p.

Research output: Contribution to journalArticle

erythritol kinase
Erythritol
Pathogens
Mycobacterium smegmatis
Terpenes
85 Citations (Scopus)

Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence

Dhiman, R. K., Mahapatra, S., Slayden, R. A., Boyne, M. E., Lenaerts, A., Hinshaw, J. C., Angala, S. K., Chatterjee, D., Biswas, K., Narayanasamy, P., Kurosu, M. & Crick, D. C., Apr 1 2009, In : Molecular Microbiology. 72, 1, p. 85-97 13 p.

Research output: Contribution to journalArticle

Vitamin K 2
Bacillus
Growth
Electron Transport
Mycobacterium tuberculosis
2008
11 Citations (Scopus)

Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-d-erythritol: a substrate for IspE

Narayanasamy, P., Eoh, H. & Crick, D. C., Jul 21 2008, In : Tetrahedron Letters. 49, 29-30, p. 4461-4463 3 p.

Research output: Contribution to journalArticle

Erythritol
Cytidine Diphosphate
High-Throughput Screening Assays
Mercaptoethanol
Substrates
5 Citations (Scopus)

Enantiomeric synthesis of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate

Narayanasamy, P. & Crick, D. C., Dec 1 2008, In : Heterocycles. 76, 1, p. 243-247 5 p.

Research output: Contribution to journalArticle

Phosphorylation
Assays
Substrates
Pharmaceutical Preparations
methyl-D-erythritol 2,4-cyclodiphosphate
2007
3 Citations (Scopus)

Acid- and base-stable esters: A new protecting group for carboxylic acids

Kurosu, M., Biswas, K., Narayanasamy, P. & Crick, D. C., Aug 16 2007, In : Synthesis. 16, p. 2513-2516 4 p.

Research output: Contribution to journalArticle

Carboxylic Acids
Carboxylic acids
Esters
Trifluoroacetic acid
Trifluoroacetic Acid
29 Citations (Scopus)

Chemoenzymatic synthesis of Park's nucleotide: toward the development of high-throughput screening for MraY inhibitors

Kurosu, M., Mahapatra, S., Narayanasamy, P. & Crick, D. C., Jan 29 2007, In : Tetrahedron Letters. 48, 5, p. 799-803 5 p.

Research output: Contribution to journalArticle

Uridine Diphosphate
Screening
Nucleotides
Throughput
Alanine
65 Citations (Scopus)

Discovery of 1,4-didydroxy-2-naphthoate prenyltransferase inhibitors: New drug leads for multidrug-resistant gram-positive pathogens

Kurosu, M., Narayanasamy, P., Biswas, K., Dhiman, R. & Crick, D. C., Aug 23 2007, In : Journal of Medicinal Chemistry. 50, 17, p. 3973-3975 3 p.

Research output: Contribution to journalArticle

Dimethylallyltranstransferase
Vitamin K 2
Pathogens
Methicillin Resistance
Methicillin
4 Citations (Scopus)

High-throughput synthesis of substituted hydrazine derivatives

Kurosu, M., Narayanasamy, P. & Crick, D. C., Dec 1 2007, In : Heterocycles. 73, C, p. 169-175 7 p.

Research output: Contribution to journalArticle

hydrazine
Throughput
Derivatives
Alkylation
Resins
12 Citations (Scopus)

Synthetic studies toward the generation of uridine-amino alcohol-based small optimized libraries

Kurosu, M., Narayanasamy, P. & Crick, D. C., Apr 13 2007, In : Heterocycles. 72, p. 339-352 14 p.

Research output: Contribution to journalArticle

Amino Alcohols
Boron
Uridine
Aldehydes
Scaffolds
2006
159 Citations (Scopus)

Macrolactonization via hydrocarbon oxidation

Fraunhoffer, K. J., Prabagaran, N., Sirois, L. E. & White, M. C., Jul 19 2006, In : Journal of the American Chemical Society. 128, 28, p. 9032-9033 2 p.

Research output: Contribution to journalArticle

sulfoxide
Maleimides
Nucleophiles
Salicylates
Alkenes
2005
60 Citations (Scopus)

Enantioselective cycloadditions with α,β-disubstituted acrylimides

Sibi, M. P., Ma, Z., Itoh, K., Prabagaran, N. & Jasperse, C. P., Jun 9 2005, In : Organic Letters. 7, 12, p. 2349-2352 4 p.

Research output: Contribution to journalArticle

Imides
Cycloaddition
imides
Cycloaddition Reaction
cycloaddition
299 Citations (Scopus)

Serial ligand catalysis: A highly selective allylic C-H oxidation

Chen, M. S., Prabagaran, N., Labenz, N. A. & White, M. C., May 18 2005, In : Journal of the American Chemical Society. 127, 19, p. 6970-6971 2 p.

Research output: Contribution to journalArticle

sulfoxide
Catalysis
Ligands
Oxidation
Alkenes
2004
36 Citations (Scopus)

Chiral relay in enantioselective conjugate radical additions using pyrazolidinone templates. How does metal geometry impact selectivity?

Sibi, M. P. & Prabagaran, N., Nov 3 2004, In : Synlett. 13, p. 2421-2424 4 p.

Research output: Contribution to journalArticle

Enantioselectivity
Metals
Lewis Acids
Geometry
Magnesium
2003
122 Citations (Scopus)

Enantioselective synthesis of α,β-disubstituted-β-amino acids

Sibi, M. P., Prabagaran, N., Ghorpade, S. G. & Jasperse, C. P., Oct 1 2003, In : Journal of the American Chemical Society. 125, 39, p. 11796-11797 2 p.

Research output: Contribution to journalArticle

Imides
Amino acids
Ligands
Amino Acids
2002
23 Citations (Scopus)

Asymmetric Michael addition reactions using a chiral La-Na aminodiolate catalyst

Prabagaran, N. & Sundararajan, G., Jun 10 2002, In : Tetrahedron Asymmetry. 13, 10, p. 1053-1058 6 p.

Research output: Contribution to journalArticle

Lanthanum
Addition reactions
lanthanum
catalysts
Catalysts
13 Citations (Scopus)

Asymmetric Michael addition reaction using a chiral catalyst containingamino diol

Prabagaran, N., Abraham, S. & Sundararajan, G., Dec 1 2002, In : Arkivoc. 2002, 7, p. 212-226 15 p.

Research output: Contribution to journalArticle

Addition reactions
Catalysts
Polymers
2001
107 Citations (Scopus)

A New Polymer-Anchored Chiral Catalyst for Asymmetric Michael Addition Reactions

Sundararajan, G. & Prabagaran, N., Feb 8 2001, In : Organic Letters. 3, 3, p. 389-392 4 p.

Research output: Contribution to journalArticle

Addition reactions
divinyl benzene
Aluminum
Lithium
Polymers
144 Citations (Scopus)

First Asymmetric Synthesis of Quinoline Derivatives by Inverse Electron Demand (IED) Diels-Alder Reaction Using Chiral Ti(IV) Complex

Sundararajan, G., Prabagaran, N. & Varghese, B., Jun 28 2001, In : Organic Letters. 3, 13, p. 1973-1976 4 p.

Research output: Contribution to journalArticle

Diels-Alder reactions
quinoline
Cycloaddition Reaction
Electrons
Derivatives