Polina V Shcherbakova, PhD

Associate Professor

  • 1440 Citations
  • 25 h-Index
1993 …2019
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Fingerprint Dive into the research topics where Polina V Shcherbakova is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 14 Similar Profiles
DNA-Directed DNA Polymerase Medicine & Life Sciences
Yeasts Medicine & Life Sciences
DNA Mismatch Repair Medicine & Life Sciences
Yeast Chemical Compounds
Mutation Medicine & Life Sciences
Mutagenesis Medicine & Life Sciences
DNA Medicine & Life Sciences
Exonucleases Medicine & Life Sciences

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Projects 2003 2019

Genomic Instability
Posters
Russia
European Union
DNA Replication
Genomic Instability
DNA-Directed DNA Polymerase
Mutation
DNA Replication
Mutagenesis
Chromosomal Instability
DNA-Directed DNA Polymerase
Chromosome Segregation
Aneuploidy
Chromosomes

Research Output 1993 2019

  • 1440 Citations
  • 25 h-Index
  • 29 Article
  • 6 Review article
  • 1 Short survey
3 Citations (Scopus)

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme

Xing, X., Kane, D. P., Bulock, C. R., Moore, E. A., Sharma, S., Chabes, A. & Shcherbakova, P. V., Dec 1 2019, In : Nature communications. 10, 1, 374.

Research output: Contribution to journalArticle

Exonucleases
DNA-Directed DNA Polymerase
enzymes
Substitution reactions
deoxyribonucleic acid
3 Citations (Scopus)

Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε

Parkash, V., Kulkarni, Y., ter Beek, J., Shcherbakova, P. V., Kamerlin, S. C. L. & Johansson, E., Dec 1 2019, In : Nature communications. 10, 1, 373.

Research output: Contribution to journalArticle

Exonucleases
DNA-Directed DNA Polymerase
Substitution reactions
deoxyribonucleic acid
cancer
6 Citations (Scopus)

Functional analysis of cancer-associated DNA polymerase ε variants in Saccharomyces cerevisiae

Barbari, S. R., Kane, D. P., Moore, E. A. & Shcherbakova, P. V., Mar 1 2018, In : G3: Genes, Genomes, Genetics. 8, 3, p. 1019-1029 11 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Saccharomyces cerevisiae
Exonucleases
DNA Mismatch Repair
Neoplasms
5 Citations (Scopus)

Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells

Mertz, T. M., Baranovskiy, A. G., Wang, J., Tahirov, T. H. & Shcherbakova, P. V., Aug 1 2017, In : Oncogene. 36, 31, p. 4427-4433 7 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Colonic Neoplasms
Nucleotides
Phenotype
Mutation
18 Citations (Scopus)

Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy

Barbari, S. R. & Shcherbakova, P. V., Aug 2017, In : DNA Repair. 56, p. 16-25 10 p.

Research output: Contribution to journalReview article

DNA-Directed DNA Polymerase
Defects
DNA Mismatch Repair
Tumors
DNA