• 2448 Citations
  • 27 h-Index
1976 …2019
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Research Output 1976 2019

  • 2448 Citations
  • 27 h-Index
  • 82 Article
  • 2 Review article
  • 1 Chapter
  • 1 Conference contribution
2019
2 Citations (Scopus)

p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance

Miller, D. R., Ingersoll, M. A., Chatterjee, A., Baker, B., Shrishrimal, S., Kosmacek, E. A., Zhu, Y., Cheng, P. W., Oberley-Deegan, R. E. & Lin, M. F., Aug 1 2019, In : Free Radical Biology and Medicine. 139, p. 24-34 11 p.

Research output: Contribution to journalArticle

Castration
Androgens
Oxidation-Reduction
Prostatic Neoplasms
Cells
2017
4 Citations (Scopus)
Mannosidases
Glycosyltransferases
Mannose
Polysaccharides
Prostatic Neoplasms
2016
8 Citations (Scopus)
Nonmuscle Myosin Type IIA
Phosphorylation
Alcohols
Hepatocytes
Actomyosin
2015
7 Citations (Scopus)
Asialoglycoprotein Receptor
Monomeric GTP-Binding Proteins
Hepatocytes
Ethanol
Down-Regulation
8 Citations (Scopus)

Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands

Chachadi, V. B., Bhat, G. & Cheng, P-W., Jan 1 2015, In : Glycobiology. 25, 9, p. 963-975 13 p.

Research output: Contribution to journalArticle

Selectins
Glycosyltransferases
Cells
Neoplasm Metastasis
Ligands
12 Citations (Scopus)
Type II Keratin
Keratin-1
Tail
Nonmuscle Myosin Type IIA
Cells
2014
12 Citations (Scopus)
Nonmuscle Myosin Type IIA
Glycosyltransferases
Heat-Shock Proteins
Shock
Hot Temperature
30 Citations (Scopus)
Galectin 1
Mucins
Polysaccharides
Prostatic Neoplasms
Apoptosis
2013
9 Citations (Scopus)
Nonmuscle Myosin Type IIA
Glycosyltransferases
Brefeldin A
Endoplasmic Reticulum
Coatomer Protein
5 Citations (Scopus)

Prostatic Cell-Specific Regulation of the Synthesis of MUC1-Associated Sialyl Lewis a

Chachadi, V. B., Ali, M. F. & Cheng, P-W., Feb 22 2013, In : PloS one. 8, 2, e57416.

Research output: Contribution to journalArticle

hydroxamic acids
synthesis
Selectins
cells
glycosyltransferases
2012
15 Citations (Scopus)

Glycosylation potential of human prostate cancer cell lines

Gao, Y., Chachadi, V. B., Cheng, P-W. & Brockhausen, I., Oct 1 2012, In : Glycoconjugate Journal. 29, 7, p. 525-537 13 p.

Research output: Contribution to journalArticle

Glycosylation
Prostatic Neoplasms
Cells
Polysaccharides
Cell Line
23 Citations (Scopus)

Glycosyltransferase-specific Golgi-targeting mechanisms

Petrosyan, A., Ali, M. F. & Cheng, P-W., Nov 2 2012, In : Journal of Biological Chemistry. 287, 45, p. 37621-37627 7 p.

Research output: Contribution to journalArticle

Glycosyltransferases
Glycosylation
Transport Vesicles
macrogolgin
18 Citations (Scopus)

Non-muscle myosin IIA transports a Golgi glycosyltransferase to the endoplasmic reticulum by binding to its cytoplasmic tail

Petrosyan, A., Ali, M. F., Verma, S. K., Cheng, H. & Cheng, P-W., Jul 1 2012, In : International Journal of Biochemistry and Cell Biology. 44, 7, p. 1153-1165 13 p.

Research output: Contribution to journalArticle

Nonmuscle Myosin Type IIA
Glycosyltransferases
Endoplasmic Reticulum
Coat Protein Complex I
Proteasome Endopeptidase Complex
2011
23 Citations (Scopus)

5-Aza-2′-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene

Chachadi, V. B., Cheng, H., Klinkebiel, D. L., Christman, J. K. & Cheng, P-W., Apr 1 2011, In : International Journal of Biochemistry and Cell Biology. 43, 4, p. 586-593 8 p.

Research output: Contribution to journalArticle

decitabine
Sialyltransferases
Galactosides
Genes
Colonic Neoplasms
16 Citations (Scopus)

Mucin O-glycan branching enzymes: Structure, function, and gene regulation

Cheng, P-W. & Radhakrishnan, P., Dec 19 2011, The Molecular Immunology of Complex Carbohydrates-3. Wu, A. (ed.). p. 465-492 28 p. (Advances in Experimental Medicine and Biology; vol. 705).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1,4-alpha-Glucan Branching Enzyme
Mucins
Gene expression
Polysaccharides
Genes
14 Citations (Scopus)

Steroids up-regulate p66Shc longevity protein in growth regulation by inhibiting its ubiquitination

Kumar, S., Kumar, S., Rajendran, M., Alam, S. M., Lin, F. F., Cheng, P-W. & Lin, M-F., Feb 1 2011, In : PloS one. 6, 1, e15942.

Research output: Contribution to journalArticle

Ubiquitination
steroids
Up-Regulation
Steroids
Growth
33 Citations (Scopus)
Sulfotransferases
Selectins
Glycosyltransferases
Prostatic Neoplasms
Genes
2009
9 Citations (Scopus)
L-Selectin
Prostatic Neoplasms
Lymph Nodes
Cells
Ligands
2008
11 Citations (Scopus)
decitabine
Dimethyl Sulfoxide
Cytomegalovirus
p38 Mitogen-Activated Protein Kinases
Chemical activation

Proteinases Release Mucin from Airways Goblet Cells

Boat, T. F., Cheng, P. W., Klinger, J. D., Liedtke, C. M. & Tandler, B., May 30 2008, Mucus and Mucosa. John Wiley and Sons Ltd., p. 72-93 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Goblet Cells
Mucins
Peptide Hydrolases
Pancreatic Elastase
Thermolysin
2007
12 Citations (Scopus)

Butyrate induces sLex synthesis by stimulation of selective glycosyltransferase genes

Radhakrishnan, P., Beum, P. V., Tan, S. & Cheng, P-W., Aug 3 2007, In : Biochemical and Biophysical Research Communications. 359, 3, p. 457-462 6 p.

Research output: Contribution to journalArticle

Glycosyltransferases
Butyrates
Genes
Tumor-Associated Carbohydrate Antigens
Glycoconjugates
13 Citations (Scopus)
Biosynthesis
Mucins
Mucus
Genes
Exons
13 Citations (Scopus)

Mucin biosynthesis: Molecular cloning and expression of mouse mucus-type core 2 β1,6 N-acetylglucosaminyltransferase

Hashimoto, M., Tan, S., Mori, N., Cheng, H. & Cheng, P-W., Sep 1 2007, In : Glycobiology. 17, 9, p. 994-1006 13 p.

Research output: Contribution to journalArticle

Cloning
Biosynthesis
Molecular Cloning
Mucins
Mucus
2005
57 Citations (Scopus)
decitabine
trichostatin A
Galactosidases
Glycosyltransferases
Butyrates
13 Citations (Scopus)

BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53

Basma, H. E., El-Refaey, H., Sgagias, M. K., Cowan, K. H., Luo, X. & Cheng, P-W., Dec 1 2005, In : Journal of Biomedical Science. 12, 6, p. 999-1011 13 p.

Research output: Contribution to journalArticle

Caspase 8
Cisplatin
Cytochromes c
Cells
Breast Neoplasms
15 Citations (Scopus)

Intratracheal budesonide-poly(lactide-co-glycolide) microparticles reduce oxidative stress, VEGF expression, and vascular leakage in a benzo(a)pyrene-fed mouse model

Bandi, N., Ayalasomayajula, S. P., Dhanda, D. S., Iwakawa, J., Cheng, P-W. & Kompella, U. B., Jul 1 2005, In : Journal of Pharmacy and Pharmacology. 57, 7, p. 851-860 10 p.

Research output: Contribution to journalArticle

Polyglactin 910
Budesonide
Benzo(a)pyrene
Vascular Endothelial Growth Factor A
Blood Vessels
22 Citations (Scopus)
Interleukin-13
Mucins
Tretinoin
Interleukin-4
Up-Regulation
2004
6 Citations (Scopus)

Identification of disulfide bonds among the nine core 2 N-acetylglucosaminyltransferase-M cysteines conserved in the mucin β6-N-acetylglucosaminyltransferase family

Singh, J., Khan, G. A., Kinarsky, L., Cheng, H., Wilken, J., Choi, K. H., Bedows, E., Sherman, S. & Cheng, P-W., Sep 10 2004, In : Journal of Biological Chemistry. 279, 37, p. 38969-38977 9 p.

Research output: Contribution to journalArticle

Mucin-6
Disulfides
Cysteine
Mucin-1
Mucins
1 Citation (Scopus)

Lung gene therapy: Clinical and regulatory issues

Amrite, A. C., Cheruvu, N. P. S., Sundaram, S., Aravalli, R. N., Cheng, P-W. & Kompella, U. B., Jul 30 2004, In : Clinical Research and Regulatory Affairs. 21, 1, p. 1-28 28 p.

Research output: Contribution to journalReview article

Genetic Therapy
Lung
Cystic Fibrosis
Ethics
Neoplasms
10 Citations (Scopus)

Mucin biosynthesis: Bovine C2GnT-M gene, tissue-specific expression, and herpes virus-4 homologue

Choi, K. H., Osorio, F. A. & Cheng, P. W., May 1 2004, In : American journal of respiratory cell and molecular biology. 30, 5, p. 710-719 10 p.

Research output: Contribution to journalArticle

Biosynthesis
Mucins
Viruses
Genes
Tissue
2003
16 Citations (Scopus)
Biosynthesis
Mucins
Epidermal Growth Factor
Adenocarcinoma
Down-Regulation
2002
33 Citations (Scopus)

Downregulation of PTEN/MMAC/TEP1 expression in human prostate cancer line DU145 by growth stimuli

Bastola, D. R., Pahwa, G. S., Lin, M-F. & Cheng, P-W., Jan 1 2002, In : Molecular and cellular biochemistry. 236, 1-2, p. 75-81 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Down-Regulation
Cells
Phosphorylation
Growth
40 Citations (Scopus)

p53 and PTEN/MMAC1/TEP1 gene therapy of human prostate PC-3 carcinoma xenograft, using transferrin-facilitated lipofection gene delivery strategy

Seki, M., Iwakawa, J., Cheng, H. & Cheng, P-W., Apr 10 2002, In : Human gene therapy. 13, 6, p. 761-773 13 p.

Research output: Contribution to journalArticle

Transferrin
Heterografts
Genetic Therapy
Prostate
Carcinoma
39 Citations (Scopus)
Transferrin
Transfection
DNA
Genes
Liposomes
2001
18 Citations (Scopus)

Biosynthesis and function of β 1,6 branched mucin-type glycans

Beum, P. V. & Cheng, P-W., Jul 11 2001, In : Advances in experimental medicine and biology. 491, p. 279-312 34 p.

Research output: Contribution to journalArticle

Mucin-6
Biosynthesis
Mucins
Polysaccharides
Enzymes
72 Citations (Scopus)

Lipopolysaccharide induces mucus cell metaplasia in mouse lung

Yanagihara, K., Seki, M. & Cheng, P. W., Jan 1 2001, In : American journal of respiratory cell and molecular biology. 24, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

Metaplasia
Mucus
Lipopolysaccharides
Lung
Messenger RNA
2000
42 Citations (Scopus)

Effects of epidermal growth factor, transferrin, and insulin on lipofection efficiency in human lung carcinoma cells

Yanagihara, K., Cheng, H. & Cheng, P-W., Jan 1 2000, In : Cancer Gene Therapy. 7, 1, p. 59-65 7 p.

Research output: Contribution to journalArticle

Open Access
Transferrin
Epidermal Growth Factor
Insulin
Carcinoma
Transfection
1999
3 Citations (Scopus)

Development of monoclonal antibodies against bovine mucin core 2 β6 N-acetylglucosaminyltransferase

Li, C. M., Joshee, N., Adler, K. B. & Cheng, P-W., Dec 1 1999, In : Glycoconjugate Journal. 16, 9, p. 555-562 8 p.

Research output: Contribution to journalArticle

Mucin-2
Mucins
Monoclonal Antibodies
Transferases
Enzymes
55 Citations (Scopus)
Pancreatic Neoplasms
Tumors
Epitopes
Cells
Cell Line
30 Citations (Scopus)

Lectin enhancement of the lipofection efficiency in human lung carcinoma cells

Yanagihara, K. & Cheng, P-W., Oct 18 1999, In : Biochimica et Biophysica Acta - General Subjects. 1472, 1-2, p. 25-33 9 p.

Research output: Contribution to journalArticle

Lectins
Cells
Carcinoma
Lung
Genes
1998
13 Citations (Scopus)

Altered expression of sialylated carbohydrate antigens in HT29 colonic carcinoma cells

Mack, D. R., Cheng, P-W., Perini, F., Wei, S. & Hollingsworth, M. A., Dec 1 1998, In : Glycoconjugate Journal. 15, 12, p. 1155-1163 9 p.

Research output: Contribution to journalArticle

Galactose
HT29 Cells
Cells
Carbohydrates
Carcinoma
15 Citations (Scopus)
Mucin-2
Cloning
Biosynthesis
Molecular Cloning
Mucins
1997
206 Citations (Scopus)

Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis

Noah, T. L., Black, H. R., Cheng, P. W., Wood, R. E. & Leigh, M. W., Jan 1 1997, In : Journal of Infectious Diseases. 175, 3, p. 638-647 10 p.

Research output: Contribution to journalArticle

Open Access
Nasal Lavage Fluid
Bronchoalveolar Lavage Fluid
Cystic Fibrosis
Cytokines
Interleukin-8
14 Citations (Scopus)

Regulation of mucin secretion in the ferret trachea

Kishioka, C., Cheng, P. W., Seftor, R. E. B., Lartey, P. A. & Rubin, B. K., Jan 1 1997, In : Otolaryngology - Head and Neck Surgery. 117, 5, p. 480-486 7 p.

Research output: Contribution to journalArticle

Ferrets
Mucins
Trachea
Leukocyte Elastase
Prostaglandins F
1996
167 Citations (Scopus)
Transferrin
Liposomes
Ligands
Gene Expression
Genes
19 Citations (Scopus)
Alveolar Epithelial Cells
Fibroblast Growth Factors
Fibroblast Growth Factor 2
Extracellular Matrix
Bromodeoxyuridine
1995
27 Citations (Scopus)

Alteration of sulfation of glycoconjugates, but not sulfate transport and intracellular inorganic sulfate content in cystic fibrosis airway epithelial cells

Mohapatra, N. K., Cheng, P. W., John, J. C., Paradiso, A. M., Yankaskas, J. R., Boucher, R. C. & Boat, T. F., Jul 1995, In : Pediatric Research. 38, 1, p. 42-48 7 p.

Research output: Contribution to journalArticle

Open Access
Glycoconjugates
Cystic Fibrosis
Sulfates
Epithelial Cells
Molecular Weight
17 Citations (Scopus)

Differential effects of ozone on lung epithelial lining fluid volume and protein content

Cheng, P. W., Boat, T. F., Shaikh, S., Wang, O. L., Hu, P. C. & Costa, D. L., Jan 1 1995, In : Experimental Lung Research. 21, 3, p. 351-365 15 p.

Research output: Contribution to journalArticle

Ozone
Linings
Albumins
Lung
Fluids
1994
40 Citations (Scopus)

Lectin conjugate directed gene transfer to airway epithelial cells

Yin, W. N. & Cheng, P. W., Nov 30 1994, In : Biochemical and Biophysical Research Communications. 205, 1, p. 826-833 8 p.

Research output: Contribution to journalArticle

Gene transfer
Lectins
Histones
Polylysine
Epithelial Cells
14 Citations (Scopus)

Production and characterization of monoclonal antibodies against guinea pig tracheal mucins

Li, C., Cheng, P. W. & Adler, K. B., Dec 1 1994, In : Hybridoma. 13, 4, p. 281-287 7 p.

Research output: Contribution to journalArticle

Mucins
Guinea Pigs
Monoclonal Antibodies
Ferrets
Immunoglobulin G