Paul H Davis, PhD

Associate Professor

  • 1133 Citations
  • 14 h-Index
20012020
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Research Output 2003 2020

  • 1133 Citations
  • 14 h-Index
  • 22 Article
  • 4 Review article
  • 1 Conference contribution
  • 1 Short survey
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Article
2020

A new chemotype with promise against Trypanosoma cruzi

Wang, X., Cal, M., Kaiser, M., Buckner, F. S., Lepesheva, G. I., Sanford, A. G., Wallick, A. I., Davis, P. H. & Vennerstrom, J. L., Jan 1 2020, In : Bioorganic and Medicinal Chemistry Letters. 30, 1, 126778.

Research output: Contribution to journalArticle

Trypanosoma cruzi
Sulfonamides
Liver Microsomes
Liver
Functional groups
2019

Assessment of Gene Expression Biomarkers in the Chilean Pencil Catfish, Trichomycterus areolatus, from the Choapa River Basin, Coquimbo Chile

Ali, J. M., Montecinos, A., Schulze, T. T., Allmon, L. G., Kallenbach, A. T., Watson, G. F., Davis, P. H., Snow, D. D., Bertin, A., Gouin, N. & Kolok, A. S., Jan 1 2019, (Accepted/In press) In : Archives of Environmental Contamination and Toxicology.

Research output: Contribution to journalArticle

Catfishes
Chile
Biomarkers
Rivers
Gene expression
2018
1 Citation (Scopus)

Derivatives of a benzoquinone acyl hydrazone with activity against Toxoplasma gondii

Sanford, A. G., Schulze, T. T., Potluri, L. P., Watson, G. F., Darner, E. B., Zach, S. J., Hemsley, R. M., Wallick, A. I., Warner, R. C., Charman, S. A., Wang, X., Vennerstrom, J. L. & Davis, P. H., Dec 2018, In : International Journal for Parasitology: Drugs and Drug Resistance. 8, 3, p. 488-492 5 p.

Research output: Contribution to journalArticle

Hydrazones
Toxoplasma
Pyrimethamine
Toxoplasmosis
Structure-Activity Relationship
3 Citations (Scopus)

Novel Toxoplasma gondii inhibitor chemotypes

Sanford, A. G., Schulze, T. T., Potluri, L. P., Hemsley, R. M., Larson, J. J., Judge, A. K., Zach, S. J., Wang, X., Charman, S. A., Vennerstrom, J. L. & Davis, P. H., Apr 2018, In : Parasitology International. 67, 2, p. 107-111 5 p.

Research output: Contribution to journalArticle

Toxoplasma
Pyrans
Cell Line
Hydrazones
Pyrimethamine
3 Citations (Scopus)

Progress in antischistosomal N,N′-diaryl urea SAR

Wu, J., Wang, C., Leas, D., Vargas, M., White, K. L., Shackleford, D. M., Chen, G., Sanford, A. G., Hemsley, R. M., Davis, P. H., Dong, Y., Charman, S. A., Keiser, J. & Vennerstrom, J. L., Feb 1 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 3, p. 244-248 5 p.

Research output: Contribution to journalArticle

Urea
Schistosoma mansoni
Solubility
Benzamides
Benzoates
2014
7 Citations (Scopus)

A novel method for simulating insulin mediated GLUT4 translocation

Jezewski, A. J., Larson, J. J., Wysocki, B., Davis, P. H. & Wysocki, T. A., Dec 1 2014, In : Biotechnology and Bioengineering. 111, 12, p. 2454-2465 12 p.

Research output: Contribution to journalArticle

Insulin
Glucose
Glucose Transporter Type 4
Endocrine System
Critical Pathways
9 Citations (Scopus)

Design, assessment, and in vivo evaluation of a computational model illustrating the role of CAV1 in CD4+ T-lymphocytes

Conroy, B. D., Herek, T. A., Shew, T. D., Latner, M., Larson, J. J., Allen, L., Davis, P. H., Helikar, T. & Cutucache, C. E., Jan 1 2014, In : Frontiers in immunology. 5, DEC, 599.

Research output: Contribution to journalArticle

Caveolin 1
T-Lymphocytes
Synapses
Cell Proliferation
T-Cell Leukemia
8 Citations (Scopus)

Estimating Bacterial Diversity in Scirtothrips dorsalis (Thysanoptera: Thripidae) via Next Generation Sequencing

Dickey, A. M., Trease, A. J., Jara-Cavieres, A., Kumar, V., Christenson, M. K., Potluri, L. P., Morgan, J. K., Shatters, R. G., McKenzie, C. L., Davis, P. H. & Osborne, L. S., Jun 2014, In : Florida Entomologist. 97, 2, p. 362-366 5 p.

Research output: Contribution to journalArticle

Scirtothrips dorsalis
Thripidae
Thysanoptera
Stenotrophomonas
insect
2013
21 Citations (Scopus)

The spring runoff in nebraska's (USA) Elkhorn River watershed and its impact on two sentinel organisms

Knight, L. A., Christenson, M. K., Trease, A. J., Davis, P. H. & Kolok, A. S., Jul 1 2013, In : Environmental Toxicology and Chemistry. 32, 7, p. 1544-1551 8 p.

Research output: Contribution to journalArticle

Agrochemicals
Springs (water)
Rana pipiens
Watersheds
Runoff
2012
17 Citations (Scopus)

Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice

Pszenny, V., Davis, P. H., Zhou, X. W., Hunter, C. A., Carruthers, V. B. & Roos, D. S., Mar 1 2012, In : Infection and immunity. 80, 3, p. 1156-1165 10 p.

Research output: Contribution to journalArticle

Serine Proteinase Inhibitors
Toxoplasma
Cysts
Parasites
Vacuoles
2011
11 Citations (Scopus)

An insertional trap for conditional gene expression in Toxoplasma gondii: Identification of TAF250 as an essential gene

Jammallo, L., Eidell, K., Davis, P. H., Dufort, F. J., Cronin, C., Thirugnanam, S., Chiles, T. C., Roos, D. S. & Gubbels, M. J., Feb 1 2011, In : Molecular and Biochemical Parasitology. 175, 2, p. 133-143 11 p.

Research output: Contribution to journalArticle

Essential Genes
Toxoplasma
Tetracycline
Gene Expression
Cell Cycle
2010
50 Citations (Scopus)

A novel multifunctional oligonucleotide microarray for Toxoplasma gondii

Bahl, A., Davis, P. H., Behnke, M., Dzierszinski, F., Jagalur, M., Chen, F., Shanmugam, D., White, M. W., Kulp, D. & Roos, D. S., Oct 25 2010, In : BMC genomics. 11, 1, 603.

Research output: Contribution to journalArticle

Toxoplasma
Oligonucleotide Array Sequence Analysis
Single Nucleotide Polymorphism
Parasites
Genome
394 Citations (Scopus)

Chemical genetics of Plasmodium falciparum

Guiguemde, W. A., Shelat, A. A., Bouck, D., Duffy, S., Crowther, G. J., Davis, P. H., Smithson, D. C., Connelly, M., Clark, J., Zhu, F., Jiménez-Díaz, M. B., Martinez, M. S., Wilson, E. B., Tripathi, A. K., Gut, J., Sharlow, E. R., Bathurst, I., Mazouni, F. E., Fowble, J. W., Forquer, I. & 15 others, McGinley, P. L., Castro, S., Angulo-Barturen, I., Ferrer, S., Rosenthal, P. J., Derisi, J. L., Sullivan, D. J., Lazo, J. S., Roos, D. S., Riscoe, M. K., Phillips, M. A., Rathod, P. K., Van Voorhis, W. C., Avery, V. M. & Guy, R. K., May 20 2010, In : Nature. 465, 7296, p. 311-315 5 p.

Research output: Contribution to journalArticle

Antimalarials
Plasmodium falciparum
Reverse Genetics
Falciparum Malaria
Toxoplasma
34 Citations (Scopus)

Differences in the transcriptome signatures of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties

Biller, L., Davis, P. H., Tillack, M., Matthiesen, J., Lotter, H., Stanley, S. L., Tannich, E. & Bruchhaus, I., Jan 26 2010, In : BMC genomics. 11, 1, 63.

Research output: Contribution to journalArticle

Entamoeba histolytica
Transcriptome
Cell Line
Virulence Factors
Virulence
151 Citations (Scopus)

Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses

Peixoto, L., Chen, F., Harb, O. S., Davis, P. H., Beiting, D. P., Brownback, C. S., Ouloguem, D. & Roos, D. S., Aug 19 2010, In : Cell Host and Microbe. 8, 2, p. 208-218 11 p.

Research output: Contribution to journalArticle

Parasites
Phosphotransferases
Genes
Toxoplasma
Organelles
2009
107 Citations (Scopus)

Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells

Chandramohanadas, R., Davis, P. H., Beiting, D. P., Harbut, M. B., Darling, C., Velmourougane, G., Lee, M. Y., Greer, P. A., Roos, D. S. & Greenbaum, D. C., May 8 2009, In : Science. 324, 5928, p. 794-797 4 p.

Research output: Contribution to journalArticle

Calpain
Toxoplasma
Parasites
Plasmodium falciparum
Genetic Suppression
23 Citations (Scopus)

Proteomic comparison of Entamoeba histolytica and Entamoeba dispar and the role of E. histolytica alcohol dehydrogenase 3 in virulence

Davis, P. H., Chen, M., Zhang, X., Clark, C. G., Townsend, R. R. & Stanley, S. L., May 19 2009, In : PLoS neglected tropical diseases. 3, 4, e415.

Research output: Contribution to journalArticle

Open Access
Entamoeba
Entamoeba histolytica
Alcohol Dehydrogenase
Proteomics
Virulence
2008
9 Citations (Scopus)

Estimating gene signals from noisy microarray images

Sarder, P., Nehorai, A., Davis, P. H. & Stanley, S. L., Jun 1 2008, In : IEEE Transactions on Nanobioscience. 7, 2, p. 142-153 12 p., 7.

Research output: Contribution to journalArticle

Microarrays
Genes
Signal to noise ratio
Sampling
Oligonucleotides
2007
66 Citations (Scopus)
Entamoeba histolytica
Cysteine Proteases
Virulence Factors
Calmodulin
Lectins
2006
72 Citations (Scopus)

Comparative proteomic analysis of two Entamoeba histolytica strains with different virulence phenotypes identifies peroxiredoxin as an important component of amoebic virulence

Davis, P. H., Zhang, X., Guo, J., Townsend, R. R. & Stanley, S. L., Sep 1 2006, In : Molecular Microbiology. 61, 6, p. 1523-1532 10 p.

Research output: Contribution to journalArticle

Peroxiredoxins
Entamoeba histolytica
Proteomics
Virulence
Amoebic Dysentery
11 Citations (Scopus)

Co-ordinate but disproportionate activation of apoptotic, regenerative and inflammatory pathways characterizes the liver response to acute amebic infection

Pelosof, L. C., Davis, P. H., Zhang, Z., Zhang, X. & Stanley, S. L., Mar 1 2006, In : Cellular Microbiology. 8, 3, p. 508-522 15 p.

Research output: Contribution to journalArticle

Liver
Chemical activation
Amoebic Liver Abscess
Entamoeba histolytica
Infection
32 Citations (Scopus)

Identification of a family of BspA like surface proteins of Entamoeba histolytica with novel leucine rich repeats

Davis, P. H., Zhang, Z., Chen, M., Zhang, X., Chakraborty, S. & Stanley, S. L., Jan 1 2006, In : Molecular and Biochemical Parasitology. 145, 1, p. 111-116 6 p.

Research output: Contribution to journalArticle

Protozoan Proteins
Molecular Sequence Data
Minisatellite Repeats
Entamoeba histolytica
Bacterial Proteins