Paul G Thomes, PhD

Assistant Professor

  • 2665 Citations
  • 14 h-Index
20082019
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Research Output 2008 2019

  • 2665 Citations
  • 14 h-Index
  • 20 Article
  • 9 Review article
  • 1 Comment/debate
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Article
2019
1 Citation (Scopus)
Ghrelin
Ethanol
Alcohols
Insulin
Nonesterified Fatty Acids
1 Citation (Scopus)

Ethanol withdrawal mitigates fatty liver by normalizing lipid catabolism

Thomes, P. G., Rasineni, K., Yang, L., Donohue, T. M., Kubik, J. L., McNiven, M. A. & Casey, C. A., Apr 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 316, 4, p. G509-G518

Research output: Contribution to journalArticle

Fatty Liver
Autophagy
Ethanol
Lipids
Liver
2018
2 Citations (Scopus)

Giantin is required for post-alcohol recovery of golgi in liver cells

Casey, C. A., Thomes, P. G., Manca, S. & Petrosyan, A., Dec 2018, In : Biomolecules. 8, 4, 150.

Research output: Contribution to journalArticle

Liver
Alcohols
Recovery
Hepatocytes
Cultured Cells
2017
2 Citations (Scopus)

Data on the effect of pro-fibrotic cytokine TGF-β on hepatic stellate cell autophagy

Thomes, P. G., Brandon-Warner, E., Li, T., Donohue, T. & Schrum, L. W., Feb 1 2017, In : Data in Brief. 10, p. 312-314 3 p.

Research output: Contribution to journalArticle

experiment
2 Citations (Scopus)

Dietary fructose augments ethanol-induced liver pathology

Thomes, P. G., Benbow, J. H., Brandon-Warner, E., Thompson, K. J., Jacobs, C., Donohue, T. & Schrum, L. W., May 1 2017, In : Journal of Nutritional Biochemistry. 43, p. 141-150 10 p.

Research output: Contribution to journalArticle

Pathology
Fructose
Liver
Ethanol
Nutrition
2016
4 Citations (Scopus)

Creatine Supplementation Does Not Prevent the Development of Alcoholic Steatosis

Ganesan, M., Feng, D., Barton, R. W., Thomes, P. G., McVicker, B. L., Tuma, D. J., Osna, N. A. & Kharbanda, K., Nov 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 11, p. 2312-2319 8 p.

Research output: Contribution to journalArticle

Creatine
S-Adenosylmethionine
S-Adenosylhomocysteine
Nutrition
Liver
6 Citations (Scopus)

Rev-erb agonist and TGF-β similarly affect autophagy but differentially regulate hepatic stellate cell fibrogenic phenotype

Thomes, P. G., Brandon-Warner, E., Li, T., Donohue, T. & Schrum, L. W., Dec 1 2016, In : International Journal of Biochemistry and Cell Biology. 81, p. 137-147 11 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Autophagy
70-kDa Ribosomal Protein S6 Kinases
Phosphorylation
Phenotype
2015
32 Citations (Scopus)

Acute and Chronic Ethanol Administration Differentially Modulate Hepatic Autophagy and Transcription Factor EB

Thomes, P. G., Trambly, C. S., Fox, H. S., Tuma, D. J. & Donohue, T., Dec 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 12, p. 2354-2363 10 p.

Research output: Contribution to journalArticle

Autophagy
Lysosomes
Ethanol
Transcription Factors
Liver
1 Citation (Scopus)

Multiple roles of betaine in protecting against alcohol-induced liver injury

Thomes, P. G., Bligh, S. M. & Kharbanda, K., Jan 1 2015, In : Food and Nutritional Components in Focus. 2015-January, 7, p. 285-310 26 p.

Research output: Contribution to journalArticle

Betaine
Liver
Alcohols
5 Citations (Scopus)

p66Shc longevity protein regulates the proliferation of human ovarian cancer cells

Muniyan, S., Chou, Y. W., Tsai, T. J., Thomes, P. G., Veeramani, S., Benigno, B. B., Walker, L. D., Mcdonald, J. F., Khan, S. A., Lin, F. F., Lele, S. M. & Lin, M-F., Aug 1 2015, In : Molecular Carcinogenesis. 54, 8, p. 618-631 14 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Proteins
Cell Proliferation
Phosphoric Monoester Hydrolases
Phosphorylation
9 Citations (Scopus)
Betaine
Methylation
Liver
Tubercidin
Ethanol
2014
11 Citations (Scopus)

Alcohol consumption decreases rat hepatic creatine biosynthesis via altered guanidinoacetate methyltransferase activity

Kharbanda, K., Todero, S. L., Moats, J. C., Harris, R. M., Osna, N. A., Thomes, P. G. & Tuma, D. J., Mar 2014, In : Alcoholism: Clinical and Experimental Research. 38, 3, p. 641-648 8 p.

Research output: Contribution to journalArticle

Guanidinoacetate N-Methyltransferase
Creatine
Biosynthesis
Alcohol Drinking
Rats
10 Citations (Scopus)

Increased methylation demand exacerbates ethanol-induced liver injury

Kharbanda, K., Todero, S. L., Thomes, P. G., Orlicky, D. J., Osna, N. A., French, S. W. & Tuma, D. J., Aug 2014, In : Experimental and Molecular Pathology. 97, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

Methylation
Liver
Ethanol
Wounds and Injuries
Nutrition
2013
15 Citations (Scopus)
Early Growth Response Protein 1
Hep G2 Cells
Ethanol
Growth
Triglycerides
43 Citations (Scopus)

Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells

Thomes, P. G., Ehlers, R. A., Trambly, C. S., Clemens, D. L., Fox, H. S., Tuma, D. J. & Donohue, T., Jan 2013, In : Autophagy. 9, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

Hep G2 Cells
Ethanol
Cytochrome P-450 CYP2E1
Alcohol Dehydrogenase
Acetaldehyde
2012
21 Citations (Scopus)

Early Growth Response-1 Contributes to Steatosis Development After Acute Ethanol Administration

Donohue, T., Osna, N. A., Trambly, C. S., Whitaker, N. P., Thomes, P. G., Todero, S. L. & Davis, J. S., May 1 2012, In : Alcoholism: Clinical and Experimental Research. 36, 5, p. 759-767 9 p.

Research output: Contribution to journalArticle

Liver
Ethanol
Fatty Liver
Growth
Endotoxins
42 Citations (Scopus)

Proteasome activity and autophagosome content in liver are reciprocally regulated by ethanol treatment

Thomes, P. G., Trambly, C. S., Thiele, G. M., Duryee, M. J., Fox, H. S., Haorah, J. & Donohue, T., Jan 6 2012, In : Biochemical and Biophysical Research Communications. 417, 1, p. 262-267 6 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Liver
Ethanol
Therapeutics
Rats
2010
48 Citations (Scopus)

Cardioprotective activity of Cladosiphon okamuranus fucoidan against isoproterenol induced myocardial infarction in rats

Thomes, P., Rajendran, M., Pasanban, B. & Rengasamy, R., Dec 15 2010, In : Phytomedicine. 18, 1, p. 52-57 6 p.

Research output: Contribution to journalArticle

Isoproterenol
Myocardial Infarction
Lipid Peroxidation
Oxidative Stress
Antioxidants
2008
29 Citations (Scopus)

Antibacterial activity of three South Indian seagrasses, Cymodocea serrulata, Halophila ovalis and Zostera capensis

Kumar, C. S., Sarada, D. V. L., Thomas, P. G. & Rengasamy, R., Sep 1 2008, In : World Journal of Microbiology and Biotechnology. 24, 9, p. 1989-1992 4 p.

Research output: Contribution to journalArticle

Zosteraceae
Methanol
Salmonella paratyphi A
Micrococcus luteus
Bacillus cereus
37 Citations (Scopus)

Toxicological evaluation of fucoidan from Cladosiphon okamuranus

Thomas, P. G. & Rengasamy, R., Dec 1 2008, In : Journal of Medicinal Food. 11, 4, p. 638-642 5 p.

Research output: Contribution to journalArticle

Toxicology
Phaeophyta
Body Weight
Seaweed
Virus Diseases