Nicole A Shonka, MD

Associate Professor

  • 458 Citations
  • 11 h-Index
20062019
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Research Output 2006 2019

  • 458 Citations
  • 11 h-Index
  • 18 Article
  • 11 Review article
  • 2 Comment/debate
  • 1 Editorial
2019
1 Citation (Scopus)

Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells

Vengoji, R., Macha, M. A., Nimmakayala, R. K., Rachagani, S., Siddiqui, J. A., Mallya, K., Gorantla, S., Jain, M., Ponnusamy, M. P., Batra, S. K. & Shonka, N., Jun 18 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 266.

Research output: Contribution to journalArticle

Open Access
temozolomide
Glioblastoma
Carcinogenesis
Neoplastic Stem Cells
Epidermal Growth Factor Receptor

Evaluating the decisions of glioma patients regarding clinical trial participation: a retrospective single provider review

Jirka, G. W., Bisselou, K. S. M., Smith, L. M. & Shonka, N., Apr 1 2019, In : Medical Oncology. 36, 4, 34.

Research output: Contribution to journalArticle

Glioma
Clinical Trials
Glioblastoma
Telemedicine
Marital Status

Highly Aggressive and Radiation-Resistant, "atypical" and Silent Pituitary Corticotrophic Carcinoma: A Case Report and Review of the Literature

Flores, L., Sleightholm, R., Neilsen, B., Baine, M., Drincic, A., Thorell, W., Shonka, N., Oupicky, D. & Zhang, C., Jan 1 2019, In : Case Reports in Oncology. 12, 1, p. 139-146 8 p.

Research output: Contribution to journalReview article

Open Access
temozolomide
Pituitary Neoplasms
Radiation
Adrenocorticotropic Hormone
Pituitary ACTH Hypersecretion

Novel therapies hijack the blood-brain barrier to eradicate glioblastoma cancer stem cells

Vengoji, R., Ponnusamy, M. P., Rachagani, S., Mahapatra, S., Batra, S. K., Shonka, N. & Macha, M. A., Mar 12 2019, In : Carcinogenesis. 40, 1, p. 2-14 13 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Glioblastoma
Blood-Brain Barrier
temozolomide
Radiotherapy

Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201

Chi, A. S., Tarapore, R. S., Hall, M. D., Shonka, N., Gardner, S., Umemura, Y., Sumrall, A., Khatib, Z., Mueller, S., Kline, C., Zaky, W., Khatua, S., Weathers, S. P., Odia, Y., Niazi, T. N., Daghistani, D., Cherrick, I., Korones, D., Karajannis, M. A., Kong, X. T. & 11 others, Minturn, J., Waanders, A., Arillaga-Romany, I., Batchelor, T., Wen, P. Y., Merdinger, K., Schalop, L., Stogniew, M., Allen, J. E., Oster, W. & Mehta, M. P., Oct 1 2019, In : Journal of Neuro-Oncology. 145, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

Glioma
Pediatrics
TIC10 compound
Radiation
Research Personnel
2 Citations (Scopus)

Post-operative perfusion and diffusion MR imaging and tumor progression in high-grade gliomas

White, M. L., Zhang, Y., Yu, F., Shonka, N., Aizenberg, M. R., Adapa, P. & Jaffar Kazmi, S. A., Mar 2019, In : PloS one. 14, 3, e0213905.

Research output: Contribution to journalArticle

Open Access
Glioma
Tumors
Perfusion
image analysis
Imaging techniques
1 Citation (Scopus)

Seizure prevalence, contributing factors, and prognostic factors in patients with leptomeningeal disease

Zima, L. A., Tulpule, S., Samson, K. & Shonka, N., Aug 15 2019, In : Journal of the neurological sciences. 403, p. 19-23 5 p.

Research output: Contribution to journalArticle

Seizures
Neoplasm Metastasis
Survival
Brain
Drug Therapy

Targeting the Sanctuary Site: Options when Breast Cancer Metastasizes to the Brain

Krishnan, M., Krishnamurthy, J. & Shonka, N., Aug 23 2019, In : Oncology (Williston Park, N.Y.). 33, 8

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasm Metastasis
Brain
Therapeutics
Incidence
2018
15 Citations (Scopus)

Natural products: A hope for glioblastoma patients

Vengoji, R., Macha, M. A., Batra, S. K. & Shonka, N. A., Apr 24 2018, In : Oncotarget. 9, 31, p. 22199-22224 26 p.

Research output: Contribution to journalReview article

temozolomide
Glioblastoma
Biological Products
Neoplastic Stem Cells
Blood-Brain Barrier

Safety of long-term anticoagulation in patients with brain metastases

Horstman, H., Gruhl, J., Smith, L. M., Ganti, A. K. P. & Shonka, N. A., Apr 1 2018, In : Medical Oncology. 35, 4, 43.

Research output: Contribution to journalArticle

Intracranial Hemorrhages
Neoplasm Metastasis
Safety
Brain
Anticoagulants
2017
27 Citations (Scopus)

Central nervous system cancers, version 1.2017 featured updates to the NCCN guidelines

Nabors, L. B., Portnow, J., Ammirati, M., Baehring, J., Brem, H., Butowski, N., Fenstermaker, R. A., Forsyth, P., Hattangadi-Gluth, J., Holdhoff, M., Howard, S., Junck, L., Kaley, T., Kumthekar, P., Loeffler, J. S., Moots, P. L., Mrugala, M. M., Nagpal, S., Pandey, M., Parney, I. & 16 others, Peters, K., Puduvalli, V. K., Ragsdale, J., Rockhill, J., Rogers, L., Rusthoven, C., Shonka, N., Shrieve, D. C., Sills, A. K., Swinnen, L. J., Tsien, C., Weiss, S., Wen, P. Y., Willmarth, N., Bergman, M. A. & Engh, A., Nov 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 11, p. 1331-1345 15 p.

Research output: Contribution to journalArticle

Glioma
Histology
Central Nervous System
Guidelines
Neoplasms
2 Citations (Scopus)

Extent of resection in glioblastoma

Shonka, N. A. & Aizenberg Ansari, M. R., Oct 2017, In : Journal of oncology practice. 13, 10, p. 641-642 2 p.

Research output: Contribution to journalComment/debate

Glioblastoma
16 Citations (Scopus)

Targeted Treatment of Brain Metastases

Shonka, N. A., Venur, V. A. & Ahluwalia, M. S., Apr 1 2017, In : Current neurology and neuroscience reports. 17, 4, 37.

Research output: Contribution to journalReview article

Neoplasm Metastasis
Brain
Therapeutics
Breast Neoplasms
Pharmaceutical Preparations
2016
13 Citations (Scopus)
Epidermal Growth Factor Receptor
Monoclonal Antibodies
Radiation
Radiation Tolerance
Cisplatin
Radiosurgery
Neoplasm Metastasis
Brain
Pharmaceutical Preparations
Therapeutics
2015
6 Citations (Scopus)

A Young Female with Metastatic Nongestational Choriocarcinoma

Yadav, B. S., Rai, B., Suri, V., Mukherjee, K. K., Bal, A., Morgan, R., Shonka, N. A., Lele, S. & Morris, G. J., Jan 1 2015, In : Seminars in Oncology. 42, 6, p. e109-e115

Research output: Contribution to journalReview article

49 Citations (Scopus)

Central nervous system cancers, version 1.2015: Featured updates to the NCCN guidelines

Nabors, L. B., Portnow, J., Ammirati, M., Baehring, J., Brem, H., Brown, P., Butowski, N., Chamberlain, M. C., Fenstermaker, R. A., Friedman, A., Gilbert, M. R., Hattangadi-Gluth, J., Holdhoff, M., Junck, L., Kaley, T., Lawson, R., Loeffler, J. S., Lovely, M. P., Moots, P. L., Mrugala, M. M. & 15 others, Newton, H. B., Parney, I., Raizer, J. J., Recht, L., Shonka, N., Shrieve, D. C., Sills, A. K., Swinnen, L. J., Tran, D., Tran, N., Vrionis, F. D., Weiss, S., Wen, P. Y., McMillian, N. & Engh, A. M., Oct 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 10, p. 1191-1202 12 p.

Research output: Contribution to journalReview article

Open Access
Central Nervous System
Guidelines
Glioma
Neoplasms
Adjuvant Chemotherapy
4 Citations (Scopus)

PC or PCV, that is the question: Primary anaplastic oligodendroglial tumors treated with procarbazine and CCNU with and without vincristine

Webre, C., Shonka, N. A., Smith, L. M., Liu, D. & De Groot, J., Oct 1 2015, In : Anticancer Research. 35, 10, p. 5467-5472 6 p.

Research output: Contribution to journalArticle

Lomustine
Procarbazine
Vincristine
Oligodendroglioma
Neoplasms

Targeted therapy for glioblastoma: Lessons learned and future directions

Shonka, N. A., Gupta, S. & Singh, P., Jul 1 2015, In : Current Cancer Therapy Reviews. 11, 1, p. 44-58 15 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Drug Therapy
Brain Neoplasms
Radiotherapy
2 Citations (Scopus)

Undifferentiated embryonal sarcoma of liver

Kallam, A., Krishnamurthy, J., Kozel, J. & Shonka, N. A., Dec 30 2015, In : Rare Tumors. 7, 4, p. 130-132 3 p., 6009.

Research output: Contribution to journalArticle

Sarcoma
docetaxel
gemcitabine
Liver
Ifosfamide
2014
47 Citations (Scopus)

Central nervous system cancers, Version 2.2014: Featured updates to the NCCN guidelines

Nabors, L. B., Portnow, J., Ammirati, M., Brem, H., Brown, P., Butowski, N., Chamberlain, M. C., DeAngelis, L. M., Fenstermaker, R. A., Friedman, A., Gilbert, M. R., Hattangadi-Gluth, J., Hesser, D., Holdhoff, M., Junck, L., Lawson, R., Loeffler, J. S., Moots, P. L., Mrugala, M. M., Newton, H. B. & 12 others, Raizer, J. J., Recht, L., Shonka, N. A., Shrieve, D. C., Sills, A. K., Swinnen, L. J., Tran, D., Tran, N., Vrionis, F. D., Wen, P. Y., McMillian, N. R. & Ho, M., Nov 1 2014, In : JNCCN Journal of the National Comprehensive Cancer Network. 12, 11, p. 1517-1523 7 p.

Research output: Contribution to journalArticle

Open Access
Central Nervous System
Radiosurgery
Guidelines
Neoplasms
Brain Neoplasms

Grade II gliomas-not so low grade

Shonka, N. A., Dec 1 2014, In : Oncology (Williston Park, N.Y.). 28, 12, 1 p.

Research output: Contribution to journalEditorial

Neoplasm Grading
Brain Neoplasms
Glioma
170 Citations (Scopus)

IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection

Beiko, J., Suki, D., Hess, K. R., Fox, B. D., Cheung, V., Cabral, M., Shonka, N. A., Gilbert, M. R., Sawaya, R., Prabhu, S. S., Weinberg, J., Lang, F. F., Aldape, K. D., Sulman, E. P., Rao, G., Mccutcheon, I. E. & Cahill, D. P., Jan 1 2014, In : Neuro-Oncology. 16, 1, p. 81-91 11 p.

Research output: Contribution to journalArticle

Astrocytoma
Survival
Glioblastoma
Glioma
Mutation
6 Citations (Scopus)

Intrathecal interleukin-2 for melanomatous meningitis?

Shonka, N. A., Kessinger, A. M. & Aizenberg Ansari, M. R., Nov 20 2014, In : Journal of Clinical Oncology. 32, 33, p. e111-e113

Research output: Contribution to journalArticle

Spinal Injections
Meningitis
Interleukin-2
Melanoma
2013
6 Citations (Scopus)

Cytokines associated with toxicity in the treatment of recurrent glioblastoma with aflibercept

Shonka, N. A., Piao, Y., Gilbert, M., Yung, A., Chang, S., Deangelis, L. M., Lassman, A. B., Liu, J., Cloughesy, T., Robins, H. I., Lloyd, R., Chen, A., Prados, M., Wen, P. Y., Heymach, J. & De Groot, J., Jun 1 2013, In : Targeted Oncology. 8, 2, p. 117-125 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Cytokines
Interleukin-13
Interleukin-10
Fatigue
19 Citations (Scopus)
temozolomide
Astrocytoma
Radiotherapy
Drug Therapy
Disease-Free Survival
2012
5 Citations (Scopus)

Adult medulloblastoma, from spongioblastoma cerebelli to the present day: A review of treatment and the integration of molecular markers

Shonka, N. A., Brandes, A. & de Groot, J. F., Jan 1 2012, In : ONCOLOGY (United States). 26, 11

Research output: Contribution to journalReview article

Primitive Neuroectodermal Tumors
Medulloblastoma
Pediatrics
Brain Neoplasms
Population

Adult medulloblastoma, from spongioblastoma cerebelli to the present day: a review of treatment and the integration of molecular markers.

Shonka, N., Brandes, A. & De Groot, J. F., Nov 2012, In : Oncology (Williston Park, N.Y.). 26, 11, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

Primitive Neuroectodermal Tumors
Medulloblastoma
Pediatrics
Brain Neoplasms
Population
2011
20 Citations (Scopus)

Cerebellar glioblastoma: A retrospective review of 21 patients at a single institution

Tsung, A. J., Prabhu, S. S., Lei, X., Chern, J. J., Benjamin Bekele, N. & Shonka, N. A., Dec 1 2011, In : Journal of Neuro-Oncology. 105, 3, p. 555-562 8 p.

Research output: Contribution to journalReview article

Glioblastoma
Disease-Free Survival
Survival
Adjuvant Chemotherapy
Confidence Intervals
7 Citations (Scopus)

Targets for therapy in ependymoma

Shonka, N. A., Sep 1 2011, In : Targeted Oncology. 6, 3, p. 163-169 7 p.

Research output: Contribution to journalReview article

Ependymoma
Drug Therapy
Glioma
Population
Therapeutics
2007
16 Citations (Scopus)

Pancytopenia due to iron deficiency worsened by iron infusion: A case report

Ganti, A. K. P., Shonka, N. A. & Haire, W. D., Dec 7 2007, In : Journal of Medical Case Reports. 1, 175.

Research output: Contribution to journalArticle

Pancytopenia
Iron-Deficiency Anemias
Iron
Thrombocytopenia
Leukocyte Count
2006
24 Citations (Scopus)

Effect of diabetes mellitus on the epidemiology and outcomes of colon cancer

Shonka, N. A., Anderson, J. R., Panwalkar, A. W., Reed, E. C., Steen, P. D. & Ganti, A. K., Dec 1 2006, In : Medical Oncology. 23, 4, p. 515-519 5 p.

Research output: Contribution to journalReview article

Colonic Neoplasms
Diabetes Mellitus
Epidemiology
Survival