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Natalia A Osna, MD, PhD

Associate Professor

 https://orcid.org/0000-0001-7498-0556
  • 1262 Citations
  • 22 h-Index
1984 …2019
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Fingerprint Dive into the research topics where Natalia A Osna is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Ethanol Medicine & Life Sciences
Liver Medicine & Life Sciences
Proteasome Endopeptidase Complex Medicine & Life Sciences
Alcohols Medicine & Life Sciences
Alcoholic Liver Diseases Medicine & Life Sciences
Hepacivirus Medicine & Life Sciences
Hepatocytes Medicine & Life Sciences
Wounds and Injuries Medicine & Life Sciences

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Projects 2005 2017

Extracellular vesicles as the vehicles for promoting liver injury induced by HIV and alcohol

Osna, N. A. & Poluektova, L. Y.

Project: Research project

Ethanol-Induced Hypomethylation Accelerates Hepatitis C Progression

Osna, N. A.

National Institutes of Health

7/1/13 → 6/30/17

Project: Research project

Hepatitis C
Hepacivirus
Ethanol
Methylation
Virus Diseases

Effects of Ethanol on Proteasome-HCV Core Protein Interactions

Osna, N. A.

National Institutes of Health

4/10/09 → 3/31/12

Project: Research project

Proteasome Endopeptidase Complex
Ethanol
Antigen Presentation
Proteins
Enzymes

Ethanol Effects on Antigen Presentation in Liver Cells

Osna, N. A.

National Institutes of Health

8/10/05 → 1/31/08

Project: Research project

Antigen Presentation
Ethanol
Liver
Hep G2 Cells
Major Histocompatibility Complex

Research Output 1984 2019

  • 1262 Citations
  • 22 h-Index
  • 62 Article
  • 15 Review article
  • 6 Editorial

Acetaldehyde suppresses the display of HBV-MHC class I complexes on HBV-expressing hepatocytes

Ganesan, M., Krutik, V. M., Makarov, E., Mathews, S., Kharbanda, K. K., Poluektova, L. Y., Casey, C. A. & Osna, N. A., Aug 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 317, 2, p. G127-G140

Research output: Contribution to journal › Article

Acetaldehyde
Major Histocompatibility Complex
Hepatitis B virus
Hepatocytes
Cytotoxic T-Lymphocytes

Human immunodeficiency virus and hepatotropic viruses comorbidities as the inducers of liver injury progression

Ganesan, M., Poluektova, L. Y., Kharbanda, K. K. & Osna, N. A., Jan 28 2019, In : World Journal of Gastroenterology. 25, 4, p. 398-410 13 p.

Research output: Contribution to journal › Article

Comorbidity
HIV
Viruses
Liver
Hepatitis B virus

Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors

Hu, H., Petrosyan, A., Osna, N. A., Liu, T., Olou, A. A., Alakhova, D. Y., Singh, P. K., Kabanov, A. V., Faber, E. A. & Bronich, T. K., Jul 28 2019, In : Journal of Controlled Release. 306, p. 149-164 16 p.

Research output: Contribution to journal › Article

Poloxamer
Proteasome Inhibitors
Multiple Myeloma
Ubiquitinated Proteins
Paraproteins
6 Citations (Scopus)

Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism

Ganesan, M., Tikhanovich, I., Vangimalla, S. S., Dagur, R. S., Wang, W., Poluektova, L. Y., Sun, Y., Mercer, D. F., Tuma, D., Weinman, S. A., Kharbanda, K. & Osna, N. A., 2018, In : CMGH. 5, 2, p. 101-112 12 p.

Research output: Contribution to journal › Article

Hepacivirus
Interferons
Ethanol
Methylation
Acetaldehyde

Hepatitis C virus-infected apoptotic hepatocytes program macrophages and hepatic stellate cells for liver inflammation and fibrosis development: Role of ethanol as a second hit

Ganesan, M., Poluektova, L. Y., Enweluzo, C., Kharbanda, K. & Osna, N. A., Oct 13 2018, In : Biomolecules. 8, 4, 113.

Research output: Contribution to journal › Article

Hepatic Stellate Cells
Macrophages
Viruses
Hepacivirus
Liver Cirrhosis