Muhammad Zahid, PhD

Research Assistant Professor

  • 1451 Citations
  • 23 h-Index
19982019
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Research Output 1998 2019

  • 1451 Citations
  • 23 h-Index
  • 70 Article
  • 1 Review article
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Article
2019

Estrogen Metabolism in African-American Women with and without Breast Cancer: A Pilot Study

Zahid, M., Mondal, B., Levan, T. D. & Rogan, E. G., Jan 22 2019, In : Chemical Research in Toxicology. 32, 1, p. 190-194 5 p.

Research output: Contribution to journalArticle

Metabolism
African Americans
Estrogens
Breast Neoplasms
DNA Adducts

Quality of sleep in patients with benign prostate hyperplasia

Zahid, M. & Siddiqui, A. T., Apr 1 2019, In : Rawal Medical Journal. 44, 2, p. 308-310 3 p.

Research output: Contribution to journalArticle

Hyperplasia
Prostate
Sleep
Quality of Life
Nocturia
3 Citations (Scopus)

Selective degradation of CDK6 by a palbociclib based PROTAC

Rana, S., Bendjennat, M., Kour, S., King, H. M., Kizhake, S., Zahid, M. & Natarajan, A., Jun 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 11, p. 1375-1379 5 p.

Research output: Contribution to journalArticle

Phosphotransferases
Degradation
Adenosine Triphosphate
Binding Sites
Cyclin-Dependent Kinases
2018
2 Citations (Scopus)

Modulation of Cellular Response to Arsenic Trioxide Toxicity by Resveratrol

Mondal, B., Chen, H., Wen, W., Cavalieri, E., Rogan, E. G. & Zahid, M., May 21 2018, In : ACS Omega. 3, 5, p. 5511-5515 5 p.

Research output: Contribution to journalArticle

Resveratrol
Arsenic
Toxicity
Modulation
NAD(P)H Dehydrogenase (Quinone)
1 Citation (Scopus)

Synthesis, antimicrobial evaluation and in silico studies of novel 2,4-disubstituted-1,3-thiazole derivatives

Masood, M. M., Irfan, M., Alam, S., Hasan, P., Queen, A., Shahid, S., Zahid, M., Azam, A. & Abid, M., Jan 1 2018, In : Letters in Drug Design and Discovery. 16, 2, p. 160-173 14 p.

Research output: Contribution to journalArticle

Thiazoles
Computer Simulation
Candida tropicalis
Bacterial Structures
Aminopeptidases
2 Citations (Scopus)

Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy

Rana, S., Sonawane, Y. A., Taylor, M. A., Kizhake, S., Zahid, M. & Natarajan, A., Dec 15 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 23-24, p. 3736-3740 5 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Hinges
Structure-Activity Relationship
Libraries
Substitution reactions
2017
45 Citations (Scopus)

Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC)

Robb, C. M., Contreras, J. I., Kour, S., Taylor, M. A., Abid, M., Sonawane, Y. A., Zahid, M., Murry, D. J., Natarajan, A. & Rana, S., Jan 1 2017, In : Chemical Communications. 53, 54, p. 7577-7580 4 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Proteolysis
Degradation
Cyclin-Dependent Kinases
Elongation
7 Citations (Scopus)

Structure-Activity Relationship Studies with Tetrahydroquinoline Analogs as EPAC Inhibitors

Sonawane, Y. A., Zhu, Y., Garrison, J. C., Ezell, E. L., Zahid, M., Cheng, X. & Natarajan, A., Nov 9 2017, In : ACS Medicinal Chemistry Letters. 8, 11, p. 1183-1187 5 p.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Heart Neoplasms
Cardiomegaly
Functional groups
Neoplasm Metastasis
2016
8 Citations (Scopus)

Suggestive evidence for the induction of colonic aberrant crypts in mice fed sodium nitrite

Zhou, L., Zahid, M., Anwar, M. M., Pennington, K. L., Cohen, S. M., Wisecarver, J. L., Shostrom, V. & Mirvish, S. S., Jan 2 2016, In : Nutrition and cancer. 68, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

Aberrant Crypt Foci
Sodium Nitrite
Nitrites
Drinking Water
Colonic Neoplasms
2015
2 Citations (Scopus)

Breast health and reducing breast cancer risk: A functional medicine approach

Muran, P. J., Muran, S. Y., Beseler, C. L., Cavalieri, E., Rogan, E. G. & Zahid, M., Jun 1 2015, In : Journal of Alternative and Complementary Medicine. 21, 6, p. 321-326 6 p.

Research output: Contribution to journalArticle

Breast
Medicine
Breast Neoplasms
Estrogens
Health
71 Citations (Scopus)

IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma

Wang, C., McKeithan, T. W., Gong, Q., Zhang, W., Bouska, A., Rosenwald, A., Gascoyne, R. D., Wu, X., Wang, J., Zahid, M., Jiang, B., Rohr, J., Cannon, A., Steidl, C., Fu, K., Li, Y., Hung, S., Weisenburger, D. D., Greiner, T. C., Smith, L. M. & 6 others, Ott, G., Rogan, E. G., Staudt, L. M., Vose, J. M., Iqbal, J. & Chan, W. C., Oct 8 2015, In : Blood. 126, 15, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

T-cells
T-Cell Lymphoma
Mutation
Peripheral T-Cell Lymphoma
Isocitrate Dehydrogenase
2014
17 Citations (Scopus)

Unbalanced estrogen metabolism in ovarian cancer

Zahid, M., Beseler, C. L., Hall, J. B., LeVan, T. D., Cavalieri, E. & Rogan, E. G., May 15 2014, In : International Journal of Cancer. 134, 10, p. 2414-2423 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Estrogens
DNA Adducts
Saliva
Alleles
7 Citations (Scopus)

Urinary excretion of N-nitroso compounds in rats fed sodium nitrite and/or hot dogs

Zhou, L., Anwar, M. M., Zahid, M., Shostrom, V. & Mirvish, S. S., Oct 20 2014, In : Chemical Research in Toxicology. 27, 10, p. 1669-1674 6 p.

Research output: Contribution to journalArticle

Nitroso Compounds
Sodium Nitrite
Rats
Dogs
Nitrites
2013
18 Citations (Scopus)

Reduced formation of depurinating estrogen-DNA adducts by sulforaphane or KEAP1 disruption in human mammary epithelial MCF-10A cells

Yang, L., Zahid, M., Liao, Y., Rogan, E. G., Cavalieri, E., Davidson, N. E., Yager, J. D., Visvanathan, K., Groopman, J. D. & Kensler, T. W., Nov 1 2013, In : Carcinogenesis. 34, 11, p. 2587-2592 6 p.

Research output: Contribution to journalArticle

DNA Adducts
Estrogens
Breast
Glutathione
DNA Damage
32 Citations (Scopus)

Unbalanced estrogen metabolism in thyroid cancer

Zahid, M., Goldner, W. S., Beseler, C. L., Rogan, E. G. & Cavalieri, E., Dec 1 2013, In : International Journal of Cancer. 133, 11, p. 2642-2649 8 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Estrogens
DNA Adducts
DNA
Tandem Mass Spectrometry
2012
17 Citations (Scopus)

Mechanism of DNA depurination by carcinogens in relation to cancer initiation

Cavalieri, E., Saeed, M., Zahid, M., Cassada, D., Snow, D. D., Miljkovic, M. & Rogan, E. G., Feb 1 2012, In : IUBMB Life. 64, 2, p. 169-179 11 p.

Research output: Contribution to journalArticle

Carcinogens
DNA Adducts
DNA
Neoplasms
Catechol Estrogens
2011
13 Citations (Scopus)

Formation of diethylstilbestrol-DNA adducts in human breast epithelial cells and inhibition by resveratrol

Hinrichs, B., Zahid, M., Saeed, M., Ali, M. F., Cavalieri, E. & Rogan, E. G., Nov 1 2011, In : Journal of Steroid Biochemistry and Molecular Biology. 127, 3-5, p. 276-281 6 p.

Research output: Contribution to journalArticle

Diethylstilbestrol
DNA Adducts
Breast
Epithelial Cells
Estrogens
22 Citations (Scopus)

Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease

Zahid, M., Saeed, M., Yang, L., Beseler, C., Rogan, E. G. & Cavalieri, E., Dec 1 2011, In : IUBMB Life. 63, 12, p. 1087-1093 7 p.

Research output: Contribution to journalArticle

DNA Adducts
Parkinson Disease
Acetylcysteine
DNA
Dietary supplements
8 Citations (Scopus)

Imbalanced estrogen metabolism in the brain: Possible relevance to the etiology of Parkinson's disease

Gaikwad, N. W., Murman, D. L., Beseler, C. L., Zahid, M., Rogan, E. G. & Cavalieri, E., Aug 1 2011, In : Biomarkers. 16, 5, p. 434-444 11 p.

Research output: Contribution to journalArticle

Metabolism
Parkinson Disease
Brain
Estrogens
Catechol Estrogens
26 Citations (Scopus)

Resveratrol and N-acetylcysteine block the cancer-initiating step in MCF-10F cells

Zahid, M., Saeed, M., Beseler, C., Rogan, E. G. & Cavalieri, E., Jan 1 2011, In : Free Radical Biology and Medicine. 50, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

Acetylcysteine
Estrogens
Quinones
DNA Adducts
Neoplasms
2010
20 Citations (Scopus)

Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease

Zahid, M., Saeed, M., Rogan, E. G. & Cavalieri, E., Jan 15 2010, In : Free Radical Biology and Medicine. 48, 2, p. 318-324 7 p.

Research output: Contribution to journalArticle

Quinones
Benzene
Dopamine
DNA
Neoplasms
21 Citations (Scopus)

N-acetylcysteine blocks formation of cancer-initiating estrogen-DNA adducts in cells

Zahid, M., Saeed, M., Ali, M. F., Rogan, E. G. & Cavalieri, E., Aug 1 2010, In : Free Radical Biology and Medicine. 49, 3, p. 392-400 9 p.

Research output: Contribution to journalArticle

DNA Adducts
Acetylcysteine
Estrogens
Metabolites
Catechol Estrogens
2009
11 Citations (Scopus)
Catechols
DNA Adducts
Polymorphism
Quinones
Metabolism
2008
62 Citations (Scopus)

Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel

Sissung, T. M., Danesi, R., Price, D. K., Steinberg, S. M., De Wit, R., Zahid, M., Gaikwad, N., Cavalieri, E., Dahut, W. L., Sackett, D. L., Figg, W. D. & Sparreboom, A., Jan 1 2008, In : Molecular cancer therapeutics. 7, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

docetaxel
Prostatic Neoplasms
Alleles
Survival
Tubulin
47 Citations (Scopus)

Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol

Zahid, M., Gaikwad, N. W., Ali, M. F., Lu, F., Saeed, M., Yang, L., Rogan, E. G. & Cavalieri, E., Jul 15 2008, In : Free Radical Biology and Medicine. 45, 2, p. 136-145 10 p.

Research output: Contribution to journalArticle

DNA Adducts
Estrogens
Metabolism
Breast
Catechol Estrogens
26 Citations (Scopus)

Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine

Venugopal, D., Zahid, M., Mailander, P. C., Meza, J. L., Rogan, E. G., Cavalieri, E. & Chakravarti, D., Mar 1 2008, In : Journal of Steroid Biochemistry and Molecular Biology. 109, 1-2, p. 22-30 9 p.

Research output: Contribution to journalArticle

Acetylcysteine
Estrogens
Breast
Epithelial Cells
Catechol Estrogens
76 Citations (Scopus)

Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells

Lu, F., Zahid, M., Wang, C., Saeed, M., Cavalieri, E. & Rogan, E. G., Jul 1 2008, In : Cancer Prevention Research. 1, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

DNA Adducts
Estrogens
Breast Neoplasms
Aryl Hydrocarbon Receptors
Cytochrome P-450 Enzyme System
2007
36 Citations (Scopus)

Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA

Zhang, Y., Gaikwad, N. W., Olson, K., Zahid, M., Cavalieri, E. & Rogan, E. G., Jul 1 2007, In : Metabolism: Clinical and Experimental. 56, 7, p. 887-894 8 p.

Research output: Contribution to journalArticle

Catechol Estrogens
Quinones
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP3A
Protein Isoforms
55 Citations (Scopus)
Catechol Estrogens
Catechol O-Methyltransferase
DNA Adducts
Metabolism
Estradiol
38 Citations (Scopus)

Inhibition of catechol-O-methyltransferase increases estrogen-DNA adduct formation

Zahid, M., Saeed, M., Lu, F., Gaikwad, N., Rogan, E. G. & Cavalieri, E., Dec 1 2007, In : Free Radical Biology and Medicine. 43, 11, p. 1534-1540 7 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
DNA Adducts
Estrogens
Catechol Estrogens
Breast Neoplasms
33 Citations (Scopus)

Inhibition of depurinating estrogen-DNA adduct formation by natural compounds

Zahid, M., Gaikwad, N. W., Rogan, E. G. & Cavalieri, E., Dec 1 2007, In : Chemical Research in Toxicology. 20, 12, p. 1947-1953 7 p.

Research output: Contribution to journalArticle

DNA Adducts
Estrogens
Lactoperoxidase
DNA
Thioctic Acid
39 Citations (Scopus)

Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis

Montano, M. M., Chaplin, L. J., Deng, H., Mesia-Vela, S., Gaikwad, N., Zahid, M. & Rogan, E. G., May 24 2007, In : Oncogene. 26, 24, p. 3587-3590 4 p.

Research output: Contribution to journalArticle

NAD(P)H Dehydrogenase (Quinone)
Tamoxifen
Estrogens
Carcinogenesis
Breast
2006
7 Citations (Scopus)

Ortho-quinones of benzene and estrogens induce hyperproliferation of human peripheral blood mononuclear cells

Chakravarti, D., Zahid, M., Backora, M., Myers, E. M., Gaikwad, N., Weisenburger, D. D., Cavalieri, E., Rogan, E. G. & Joshi, S. S., Dec 1 2006, In : Leukemia and Lymphoma. 47, 12, p. 2635-2644 10 p.

Research output: Contribution to journalArticle

Quinones
Benzene
Blood Cells
Estrogens
DNA Adducts
126 Citations (Scopus)
Tumors
Catechol Estrogens
DNA
Neoplasms
Lactoperoxidase
2005
33 Citations (Scopus)
Hexestrol
Deoxyribose
Catechol Estrogens
Estradiol Congeners
Quinones
37 Citations (Scopus)
Catechol Estrogens
Catechols
Estradiol Congeners
Oxidants
Estradiol
2004
8 Citations (Scopus)

Protein and amino acids contents of Libyan dates at three stages of development

Ishurd, O., Zahid, M., Xiao, P. & Pan, Y., Apr 15 2004, In : Journal of the Science of Food and Agriculture. 84, 5, p. 481-484 4 p.

Research output: Contribution to journalArticle

dates (fruit)
aspartic acid
glutamic acid
Amino Acids
Aspartic Acid
2003
16 Citations (Scopus)

A convenient method for the synthesis of cyclic trithiocarbonates on carbohydrate scaffolds

Saeed, M., Abbas, M., Abdel-Jalil, R. J., Zahid, M. & Voelter, W., Jan 6 2003, In : Tetrahedron Letters. 44, 2, p. 315-317 3 p.

Research output: Contribution to journalArticle

Scaffolds
Carbohydrates
Pentoses
Skeleton
Sodium
3 Citations (Scopus)

New glycosides from Salvia moorcroftiana (Lamiaceae)

Zahid, M., Saeed, M., Asim, M., Ishrud, O., Wu, S., Ahmad, V. U. & Pan, Y., Aug 4 2003, In : Helvetica Chimica Acta. 86, 6, p. 2021-2027 7 p.

Research output: Contribution to journalArticle

Salvia
Lamiaceae
Glycosides
Flavonoids
glucosides
10 Citations (Scopus)

New triterpenoids from Corchorus trilocularis

Ahmed, A., Asim, M., Zahid, M., Ali, A. & Ahmad, V. U., Jul 2003, In : Chemical and Pharmaceutical Bulletin. 51, 7, p. 851-853 3 p.

Research output: Contribution to journalArticle

Open Access
Corchorus
Glucosides
Esters
Acids
2002
22 Citations (Scopus)

Flavonoid glycosides from Salvia moorcroftiana Wall

Zahid, M., Ishrud, O., Pan, Y., Asim, M., Riaz, M. & Uddin Ahmad, V., Mar 1 2002, In : Carbohydrate Research. 337, 5, p. 403-407 5 p.

Research output: Contribution to journalArticle

Salvia
Glycosides
Galactose
Flavonoids
Lamiaceae
12 Citations (Scopus)

New cycloartane and flavonol glycosides from Corchorus depressus

Zahid, M., Ali, A., Ishurd, O., Ahmed, A., Ali, Z., Ahmad, V. U. & Pan, Y., Mar 25 2002, In : Helvetica Chimica Acta. 85, 2, p. 689-697 9 p.

Research output: Contribution to journalArticle

Corchorus
triols
Glycosides
glucosides
Galactose
23 Citations (Scopus)

Pharmacological activities of crude acetone extract and purified constituents of Salvia moorcraftiana Wall

Khan, T., Zahid, M., Asim, M., Shahzad-ul-Hussan, Iqbal, Z., Choudhary, M. I. & Ahmad, V. U., Dec 2002, In : Phytomedicine. 9, 8, p. 749-752 4 p.

Research output: Contribution to journalArticle

Salvia
Glucosidases
Enzyme inhibition
Artemia
Lemna
4 Citations (Scopus)

Three new diterpenoids from Euphorbia decipiens

Ahmad, V. U., Hussain, H., Jassbi, A. R., Zahid, M., Hussain, J., Bukhari, I. A., Yasin, A. & Choudhary, M. I., Dec 1 2002, In : Polish Journal of Chemistry. 76, 12, p. 1699-1706 8 p.

Research output: Contribution to journalArticle

prolyl oligopeptidase
Diterpenes
Analgesics
Esters
Nuclear magnetic resonance
2001
30 Citations (Scopus)

A water-soluble galactomannan from the seeds of Phoenix dactylifera L.

Ishrud, O., Zahid, M., Zhou, H. & Pan, Y., Oct 16 2001, In : Carbohydrate Research. 335, 4, p. 297-301 5 p.

Research output: Contribution to journalArticle

Polysaccharides
Seed
Seeds
Galactosidases
Methylation
3 Citations (Scopus)

Chemical Constituents of Salvia cabulica

Yasmeen, S., Ali, A., Zahid, M., Tareen, R. B. & Ahmad, V. U., Dec 1 2001, In : Journal of Chemical Society of Pakistan. 23, 4, p. 240-242 3 p.

Research output: Contribution to journalArticle

Nuclear magnetic resonance
Esters
Experiments
phloretic acid
2 Citations (Scopus)

Constituents of Salvia moorcroftiana

Ishurd, O., Zahid, M., Khan, T. & Pan, Y., Sep 11 2001, In : Fitoterapia. 72, 6, p. 720-721 2 p.

Research output: Contribution to journalArticle

Salvia
Esters
3-oxodecan-1-o1 p-hydroxybenzoate
11 Citations (Scopus)

Coumarins from the aerial part of Halocnemum strobilaceum

Miftakhova, A. F., Burasheva, G. S., Abilov, Z. A., Ahmad, V. U. & Zahid, M., Apr 18 2001, In : Fitoterapia. 72, 3, p. 319-321 3 p.

Research output: Contribution to journalArticle

Coumarins
coumarin 7
heraclenin
oreoselone
7-hydroxy-3-methylcoumarin
13 Citations (Scopus)

Eight new diterpenoids from Euphorbia decipiens

Zahid, M., Husani, S. R., Abbas, M., Pan, Y., Jassbi, A. R., Asim, M., Parvez, M., Voelter, W. & Ahmad, V. U., Sep 11 2001, In : Helvetica Chimica Acta. 84, 7, p. 1980-1988 9 p.

Research output: Contribution to journalArticle

Euphorbia
Diterpenes
esters
isolation
Esters
39 Citations (Scopus)

Isolation and structure analysis of a glucomannan from the seeds of Libyan dates

Ishrud, O., Zahid, M., Ahmad, V. U. & Pan, Y., Sep 17 2001, In : Journal of Agricultural and Food Chemistry. 49, 8, p. 3772-3774 3 p.

Research output: Contribution to journalArticle

dates (fruit)
Seed
Seeds
Methylation
Ion Exchange