Michael Floyd Sorrell, MD

Professor

  • 7982 Citations
  • 50 h-Index
1970 …2017
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Research Output 1970 2017

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Article
2017
7 Citations (Scopus)

Favorable Outcomes of Preterm Infants with Parenteral Nutrition-associated Liver Disease Treated with Intravenous Fish Oil-based Lipid Emulsion

Sorrell, M., Moreira, A., Green, K., Jacob, R., Tragus, R., Keller, L., Quinn, A., McCurnin, D., Gong, A., El Sakka, A., Mittal, N. & Blanco, C., May 1 2017, In : Journal of pediatric gastroenterology and nutrition. 64, 5, p. 783-788 6 p.

Research output: Contribution to journalArticle

Fish Oils
Parenteral Nutrition
Emulsions
Premature Infants
Liver Diseases
2016

JOHN L. GOLLAN, MD, PhD: 1942 - 2015

Sorrell, M. F., Jan 1 2016, In : Transactions of the American Clinical and Climatological Association. 127, p. xcii-xciv

Research output: Contribution to journalArticle

21st Century History
20th Century History
Tasmania
Gastroenterology
Biochemistry
2015

John L. Gollan, M.D., Ph.D., March 3, 1942-January 6, 2015

Sorrell, M. F., Apr 1 2015, In : Hepatology (Baltimore, Md.). 61, 4, p. 1444-1445 2 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Gastroenterology
2011
2 Citations (Scopus)

Impact of betaine on hepatic fibrosis and homocysteine in nonalcoholic steatohepatitis - A prospective, cohort study

Mukherjee, S., Bernard, T., Kharbanda, K., Barak, A. J., Sorrell, M. F. & Tuma, D. J., Oct 11 2011, In : Open Translational Medicine Journal. 3, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

Betaine
Homocysteine
Fibrosis
Cohort Studies
Prospective Studies
1 Citation (Scopus)

Preface

Schiff, E. R., Maddrey, W. C. & Sorrell, M. F., Oct 31 2011, In : Unknown Journal.

Research output: Contribution to journalArticle

2009
199 Citations (Scopus)

National Institutes of Health consensus development conference statement: Management of hepatitis B

Sorrell, M. F., Belongia, E. A., Costa, J., Gareen, I. F., Grem, J. L., Inadomi, J. M., Kern, E. R., McHugh, J. A., Petersen, G. M., Rein, M. F., Strader, D. B. & Trotter, H. T., Jan 20 2009, In : Annals of internal medicine. 150, 2, p. 104-110 7 p.

Research output: Contribution to journalArticle

Open Access
Consensus Development Conferences
National Institutes of Health (U.S.)
Hepatitis B
Health Services Research
Contracts
79 Citations (Scopus)

National Institutes of Health consensus development conference statement: Management of hepatitis B

Sorrell, M. F., Belongia, E. A., Costa, J., Gareen, I. F., Grem, J. L., Inadomi, J. M., Kern, E. R., McHugh, J. A., Petersen, G. M., Rein, M. F., Strader, D. B. & Trotter, H. T., May 1 2009, In : Hepatology. 49, SUPPL. 5, p. S4-S12

Research output: Contribution to journalArticle

Consensus Development Conferences
Chronic Hepatitis B
National Institutes of Health (U.S.)
Hepatitis B
Research
2008
25 Citations (Scopus)

Controversies in Liver Transplantation for Hepatitis C

Mukherjee, S. & Sorrell, M. F., May 2008, In : Gastroenterology. 134, 6, p. 1777-1788 12 p.

Research output: Contribution to journalArticle

Hepatitis C
Liver Transplantation
Transplants
Antiviral Agents
Immunosuppression
54 Citations (Scopus)

NIH consensus development statement on management of hepatitis B

Belongia, E. A., Costa, J., Gareen, I. F., Grem, J. L., Inadomi, J. M., Kern, E. R., McHugh, J. A., Petersen, G. M., Rein, M. F., Sorrell, M. F., Strader, D. B. & Trotter, H. T., Jan 1 2008, In : NIH consensus and state-of-the-science statements. 25, 2, p. 1-29 29 p.

Research output: Contribution to journalArticle

Hepatitis B
Consensus
Fibrosis
Hepatocellular Carcinoma
DNA
2007
29 Citations (Scopus)
Betaine
Methyltransferases
Alcohols
Liver
Proteins
120 Citations (Scopus)

Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway

Kharbanda, K., Mailliard, M. E., Baldwin, C. R., Beckenhauer, H. C., Sorrell, M. F. & Tuma, D. J., Feb 1 2007, In : Journal of Hepatology. 46, 2, p. 314-321 8 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamine N-Methyltransferase
Betaine
Phosphatidylcholines
S-Adenosylhomocysteine
S-Adenosylmethionine
2006

Budd-Chiari syndrome: Case report

Sorrell, M. F., Nov 1 2006, In : Liver Transplantation. 12, 11 SUPPL. 2, p. S20

Research output: Contribution to journalArticle

Budd-Chiari Syndrome
Hepatic Veins
X Ray Computed Tomography
Hepatomegaly
Phlebography
15 Citations (Scopus)

Chronic ethanol treatment impairs Rac and Cdc42 activation in rat hepatocytes

Schaffert, C. S., Todero, S. L., Casey, C. A., Thiele, G. M., Sorrell, M. F. & Tuma, D. J., Jul 1 2006, In : Alcoholism: Clinical and Experimental Research. 30, 7, p. 1208-1213 6 p.

Research output: Contribution to journalArticle

Rats
Hepatocytes
Ethanol
Chemical activation
GTP Phosphohydrolases
2005
63 Citations (Scopus)

A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes

Kharbanda, K., Rogers, D. D., Mailliard, M. E., Siford, G. L., Barak, A. J., Beckenhauer, H. C., Sorrell, M. F. & Tuma, D. J., Mar 1 2005, In : Journal of Nutrition. 135, 3, p. 519-524 6 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Betaine
S-adenosylmethionine
homocysteine
betaine
65 Citations (Scopus)

Fulminant liver failure associated with the use of black cohosh

Levitsky, J., Alli, T. A., Wisecarver, J. L. & Sorrell, M. F., Mar 2005, In : Digestive Diseases and Sciences. 50, 3, p. 538-539 2 p.

Research output: Contribution to journalArticle

Severity of Illness Index
Cimicifuga
Combined Modality Therapy
Acute Liver Failure
Liver Function Tests
28 Citations (Scopus)

Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol

Thiele, G. M., Duryee, M. J., Freeman, T. L., Sorrell, M. F., Willis, M. S., Tuma, D. J. & Klassen, L. W., Nov 25 2005, In : Biochemical Pharmacology. 70, 11, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

Acetaldehyde
Endothelial cells
Metabolites
Malondialdehyde
Liver
66 Citations (Scopus)

Role of elevated S-adenosylhomocysteine in rat hepatocyte apoptosis: Protection by betaine

Kharbanda, K., Rogers, D. D., Mailliard, M. E., Siford, G. L., Barak, A. J., Beckenhauer, H. C., Sorrell, M. F. & Tuma, D. J., Dec 5 2005, In : Biochemical Pharmacology. 70, 12, p. 1883-1890 8 p.

Research output: Contribution to journalArticle

S-Adenosylhomocysteine
Betaine
Rats
Hepatocytes
Apoptosis
2004
35 Citations (Scopus)

Transforming growth factor-β induces contraction of activated hepatic stellate cells

Kharbanda, K., Rogers, D. D., Wyatt, T. A., Sorrell, M. F. & Tuma, D. J., Jul 1 2004, In : Journal of Hepatology. 41, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Transforming Growth Factors
Smooth Muscle
Actins
Gels
28 Citations (Scopus)

WIF-B cells as a model for alcohol-induced hepatocyte injury

Schaffert, C. S., Todero, S. L., McVicker, B. L., Tuma, P. L., Sorrell, M. F. & Tuma, D. J., Jun 1 2004, In : Biochemical Pharmacology. 67, 11, p. 2167-2174 8 p.

Research output: Contribution to journalArticle

Hepatocytes
B-Lymphocytes
Ethanol
Cells
Alcohols
2003
24 Citations (Scopus)

Ethanol metabolism results in a G2/M cell-cycle arrest in recombinant Hep G2 cells

Clemens, D. L., Calisto, L. E., Sorrell, M. F. & Tuma, D. J., Aug 1 2003, In : Hepatology. 38, 2, p. 385-393 9 p.

Research output: Contribution to journalArticle

G2 Phase Cell Cycle Checkpoints
Cyclin B1
Hep G2 Cells
Ethanol
Cell Cycle
2002
45 Citations (Scopus)
T-cells
Acetaldehyde
Cell proliferation
Malondialdehyde
Antibody Formation
22 Citations (Scopus)
Hepatic Stellate Cells
Acetaldehyde
Urokinase-Type Plasminogen Activator
Malondialdehyde
Protein Kinase C
30 Citations (Scopus)

Ethanol promotes intestinal tumorigenesis in the MIN mouse

Roy, H. K., Gulizia, J. M., Karolski, W. J., Ratashak, A., Sorrell, M. F. & Tuma, D., Nov 1 2002, In : Cancer Epidemiology Biomarkers and Prevention. 11, 11, p. 1499-1502 4 p.

Research output: Contribution to journalArticle

Carcinogenesis
Ethanol
Acetaldehyde
Malondialdehyde
Neoplasms
52 Citations (Scopus)

Intestinal transplantation at the University of Nebraska Medical Center: 1990 to 2001

Langnas, A. N., Chinnakotla, S., Sudan, D., Horslen, S., McCashland, T. M., Schafer, D. F., Sorrell, M. F., Vanderhoof, J., Iyer, K., Fox, I. & Shaw, B., Jun 5 2002, In : Transplantation Proceedings. 34, 3, p. 958-960 3 p.

Research output: Contribution to journalArticle

Intestinal Diseases
Homologous Transplantation
Preschool Children
Graft Survival
Liver Transplantation
11 Citations (Scopus)
Acetaldehyde
Cell proliferation
Cell death
Malondialdehyde
Antigen-Presenting Cells
218 Citations (Scopus)

Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma

Sudan, D., DeRoover, A., Chinnakotla, S., Fox, I., Shaw, B., McCashland, T. M., Sorrell, M. F., Tempero, M. & Langnas, A. N., Sep 1 2002, In : American Journal of Transplantation. 2, 8, p. 774-779 6 p.

Research output: Contribution to journalArticle

Klatskin Tumor
Chemoradiotherapy
Transplantation
Survival
Liver Transplantation
60 Citations (Scopus)

Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells

Clemens, D. L., Forman, A., Jerrells, T. R., Sorrell, M. F. & Tuma, D. J., Jan 1 2002, In : Hepatology. 35, 5, p. 1196-1204 9 p.

Research output: Contribution to journalArticle

Acetaldehyde
Hepatocellular Carcinoma
Cell Survival
Ethanol
2-Propanol
2001
48 Citations (Scopus)

Elucidation of reaction scheme describing malondialdehyde - Acetaldehyde - Protein adduct formation

Tuma, D. J., Kearley, M. L., Thiele, G. M., Worrall, S., Haver, A., Klassen, L. W. & Sorrell, M. F., Jul 30 2001, In : Chemical Research in Toxicology. 14, 7, p. 822-832 11 p.

Research output: Contribution to journalArticle

Acetaldehyde
Malondialdehyde
Liver
Ethanol
Proteins
24 Citations (Scopus)
Integrins
Rats
Hepatocytes
Ethanol
Extracellular Matrix
41 Citations (Scopus)

Lipoatrophic diabetes and end-stage liver disease secondary to nonalcoholic steatohepatitis with recurrence after liver transplantation

Cauble, M. S., Gilroy, R., Sorrell, M. F., Mailliard, M. E., Sudan, D. L., Anderson, J. C., Wisecarver, J. L., Balakrishnan, S. & Larsen, J. L., Apr 15 2001, In : Transplantation. 71, 7, p. 892-895 4 p.

Research output: Contribution to journalArticle

Lipoatrophic Diabetes Mellitus
End Stage Liver Disease
Liver Transplantation
Recurrence
Transplantation
45 Citations (Scopus)

Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells

Kharbanda, K., Todero, S. L., Shubert, K. A., Sorrell, M. F. & Tuma, D. J., Dec 1 2001, In : Alcohol. 25, 2, p. 123-128 6 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Acetaldehyde
Malondialdehyde
Chemokines
alcoholism
14 Citations (Scopus)

Methotrexate therapy for refractory chronic active autoimmune hepatitis

Venkataramani, A., Jones, M. B. & Sorrell, M. F., Dec 1 2001, In : American Journal of Gastroenterology. 96, 12, p. 3432-3434 3 p.

Research output: Contribution to journalArticle

Autoimmune Hepatitis
Chronic Hepatitis
Immunosuppressive Agents
Methotrexate
Chronic Disease
2000
22 Citations (Scopus)

Intestinal transplantation: A single-center experience

Langnas, A. N., Sudan, D. L., Kaufman, S., Fox, I., Horslen, S., McCashland, T. M., Sorrell, M. F., Schafer, D. F., Donovan, J. & Shaw, B. W., Oct 5 2000, In : Transplantation Proceedings. 32, 6, 1 p.

Research output: Contribution to journalArticle

Liver transplantation and organ procurement.

Sorrell, J. H. & Sorrell, M. F., Aug 2000, In : Current gastroenterology reports. 2, 4, p. 265-267 3 p.

Research output: Contribution to journalArticle

Tissue and Organ Procurement
Liver Transplantation
Patient Selection
Tissue Donors
1999
6 Citations (Scopus)
Acetaldehyde
Antigen Presentation
Epitopes
Phenotype
Antigens
12 Citations (Scopus)

Ethanol feeding selectively impairs the spreading of rat perivenous hepatocytes on extracellular matrix substrates

Tuma, D. J., Smith, T. E., Schaffert, C. S., Kharbanda, K. K. & Sorrell, M. F., Oct 1999, In : Alcoholism: Clinical and Experimental Research. 23, 10, p. 1673-1680 8 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Rats
Hepatocytes
Ethanol
Substrates
1998
134 Citations (Scopus)

Cerebral oedema and increased intracranial pressure in chronic liver disease

Donovan, J. P., Schafer, D. F., Shaw, B. W. & Sorrell, M. F., Mar 7 1998, In : Lancet. 351, 9104, p. 719-721 3 p.

Research output: Contribution to journalArticle

Brain Edema
Intracranial Pressure
Liver Diseases
Chronic Disease
Intracranial Hypertension
9 Citations (Scopus)

Chronic ethanol ingestion impairs TGF-α-stimulated receptor autophosphorylation

Tuma, D. J., Todero, S. L., Barak-Bernhagen, M., Casey, C. A. & Sorrell, M. F., Apr 1 1998, In : Alcohol. 15, 3, p. 233-238 6 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
Ethanol
Eating
Hepatocytes
70 Citations (Scopus)

Detection of circulating antibodies to malondialdehyde-acetaldehyde adducts in ethanol-fed rats

Xu, D., Thiele, G. M., Beckenhauer, J. L., Klassen, L. W., Sorrell, M. F. & Tuma, D. J., Jan 1 1998, In : Gastroenterology. 115, 3, p. 686-692 7 p.

Research output: Contribution to journalArticle

Acetaldehyde
Malondialdehyde
Ethanol
Antibodies
Epitopes
11 Citations (Scopus)

Ethanol oxidation mediates impaired hepatic receptor-mediated enocytosis

Clemens, D. L., Casey, C. A., Sorrell, M. F. & Tuma, D. J., Jul 8 1998, In : Alcoholism: Clinical and Experimental Research. 22, 4, p. 778-779 2 p.

Research output: Contribution to journalArticle

Genetic Transduction
Asialoglycoprotein Receptor
Experimental Liver Neoplasms
Alcoholic Liver Diseases
Transformed Cell Line
80 Citations (Scopus)

Soluble proteins modified with acetaldehyde and malondialdehyde are immunogenic in the absence of adjuvant

Thiele, G. M., Tuma, D. J., Willis, M. S., Miller, J. A., McDonald, T. L., Sorrell, M. F. & Klassen, L. W., Nov 1998, In : Alcoholism: Clinical and Experimental Research. 22, 8, p. 1731-1739 9 p.

Research output: Contribution to journalArticle

Acetaldehyde
Malondialdehyde
Epitopes
Antibodies
Antibody Formation
1997
7 Citations (Scopus)

Coumarin-induced hepatic necrosis

Ghosh, P., Markin, R. S. & Sorrell, M. F., Feb 1 1997, In : American Journal of Gastroenterology. 92, 2, p. 348-349 2 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Coumarins
Antineoplastic Agents
Prostatic Neoplasms
Necrosis
59 Citations (Scopus)

Epitope characterization of malondialdehyde-acetaldehyde adducts using an enzyme-Linked immunosorbent assay

Xu, D., Thiele, G. M., Kearley, M. L., Haugen, M. D., Klassen, L. W., Sorrell, M. F. & Turna, D. J., Sep 1 1997, In : Chemical Research in Toxicology. 10, 9, p. 978-986 9 p.

Research output: Contribution to journalArticle

Immunosorbents
Acetaldehyde
Malondialdehyde
Epitopes
Assays
51 Citations (Scopus)
Open Access
Alcoholic Liver Diseases
National Institutes of Health (U.S.)
Liver Transplantation
Patient Selection
Alcoholism
14 Citations (Scopus)

Power failure, liver failure

Schafer, D. F. & Sorrell, M. F., 1997, In : New England Journal of Medicine. 336, 16, p. 1173-1174 2 p.

Research output: Contribution to journalArticle

Biological Toxins
Bacterial Toxins
Rhabdomyolysis
Foodborne Diseases
Bacillus cereus
1 Citation (Scopus)

Pre-liver transplant: TIPS versus distal splenorenal shunt.

Faust, T. W. & Sorrell, M. F., 1997, In : HPB surgery : a world journal of hepatic, pancreatic and biliary surgery. 10, 4, p. 261-265 5 p.

Research output: Contribution to journalArticle

Open Access
Surgical Splenorenal Shunt
Transjugular Intrahepatic Portasystemic Shunt
Gastrointestinal Hemorrhage
Esophageal and Gastric Varices
Liver Transplantation
4 Citations (Scopus)

The role of the transjugular intrahepatic portal-systemic shunt in the management of variceal bleeding.

Faust, T. W. & Sorrell, M. F., May 1997, In : Clinics in liver disease. 1, 1, p. 85-98, xi

Research output: Contribution to journalArticle

Hemorrhage
End Stage Liver Disease
APACHE
Hepatic Encephalopathy
Phlebography
1996
5 Citations (Scopus)

A 47-year-old man with asymptomatic hepatitis C infection

Sorrell, M. F. & Walzer, J., Apr 3 1996, In : Journal of the American Medical Association. 275, 13, p. 1023-1029 7 p.

Research output: Contribution to journalArticle

Viral Sexually Transmitted Diseases
Hepatitis C
Immunoblotting
Interferon-alpha
Hepacivirus
187 Citations (Scopus)
Acetaldehyde
Malondialdehyde
Ethanol
Liver
Proteins
13 Citations (Scopus)

Developing a world view toward acute liver failure

Lee, W. M. & Sorrell, M. F., Jul 1996, In : Hepatology. 24, 1, p. 270-271 2 p.

Research output: Contribution to journalArticle

Acute Liver Failure