Maneesh Jain, PhD

Assistant Professor

  • 4210 Citations
  • 28 h-Index
20012020
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Research Output 2001 2019

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Article
2019
Open Access
temozolomide
Glioblastoma
Carcinogenesis
Neoplastic Stem Cells
Epidermal Growth Factor Receptor

Amphiphilic polyanhydride-based recombinant MUC4β-nanovaccine activates dendritic cells

Banerjee, K., Gautam, S. K., Kshirsagar, P., Ross, K. A., Spagnol, G., Sorgen, P. L., Wannemuehler, M. J., Narasimhan, B., Solheim, J. C., Kumar, S., Batra, S. K. & Jain, M., Jan 1 2019, In : Genes and Cancer. 10, 3-4, p. 52-62 11 p.

Research output: Contribution to journalArticle

Open Access
Mucin-4
Polyanhydrides
Dendritic Cells
Nanoparticles
Pancreatic Neoplasms
4 Citations (Scopus)

Label-free characterization of exosome via surface enhanced Raman spectroscopy for the early detection of pancreatic cancer

Carmicheal, J., Hayashi, C., Huang, X., Liu, L., Lu, Y., Krasnoslobodtsev, A. V., Lushnikov, A., Kshirsagar, P. G., Patel, A., Jain, M., Lyubchenko, Y. L., Lu, Y., Batra, S. K. & Kaur, S., Feb 1 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 16, p. 88-96 9 p.

Research output: Contribution to journalArticle

Exosomes
Raman Spectrum Analysis
Pancreatic Neoplasms
Early Detection of Cancer
Raman spectroscopy
2018
5 Citations (Scopus)

Desmoplasia in pancreatic ductal adenocarcinoma: Insight into pathological function and therapeutic potential

Cannon, A., Thompson, C., Hall, B. R., Jain, M., Kumar, S. & Batra, S. K., Mar 1 2018, In : Genes and Cancer. 9, 3-4, p. 78-86 9 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Therapeutics
Research
2 Citations (Scopus)

Development and characterization of carboxy-terminus specific monoclonal antibodies for understanding MUC16 cleavage in human ovarian cancer

Aithal, A., Junker, W. M., Kshirsagar, P., Das, S., Kaur, S., Orzechowski, C., Gautam, S. K., Jahan, R., Sheinin, Y. M., Lakshmanan, I., Palanimuthu Ponnusamy, M., Batra, S. K. & Jain, M., Apr 1 2018, In : PLoS One. 13, 4, e0193907.

Research output: Contribution to journalArticle

ovarian neoplasms
Ovarian Neoplasms
monoclonal antibodies
Monoclonal Antibodies
Antigens
2017
18 Citations (Scopus)

A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study

Kaur, S., Smith, L. M., Patel, A., Menning, M., Watley, D. C., Malik, S. S., Krishn, S. R., Mallya, K., Aithal, A., Sasson, A. R., Johansson, S. L., Jain, M., Singh, S., Guha, S., Are, C., Raimondo, M., Hollingsworth, M. A., Brand, R. E. & Batra, S. K., Jan 1 2017, In : American Journal of Gastroenterology. 112, 1, p. 172-183 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Multicenter Studies
Chronic Pancreatitis
Mucins
Radioimmunoassay
12 Citations (Scopus)

Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

Macha, M. A., Rachagani, S., Qazi, A. K., Jahan, R., Gupta, S., Patel, A. A., Seshacharyulu, P., Lin, C., Li, S., Wang, S., Verma, V., Kishida, S., Kishida, M., Nakamura, N., Kibe, T., Lydiatt, W. M., Smith, R. B., Ganti, A. K. P., Jones, D. T., Batra, S. K. & 1 others, Jain, M., Jan 1 2017, In : Oncotarget. 8, 13, p. 20961-20973 13 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Ionizing Radiation
Epidermal Growth Factor Receptor
Heterografts
Radiation-Induced Neoplasms
8 Citations (Scopus)

Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: Clinical implication for improved colon surveillance

Krishn, S. R., Kaur, S., Sheinin, Y. M., Smith, L. M., Gautam, S. K., Patel, A., Jain, M., Juvvigunta, V., Pai, P., Lazenby, A. J., Roy, H. K. & Batra, S. K., 2017, In : Oncotarget. 8, 4, p. 7025-7038 14 p.

Research output: Contribution to journalArticle

Mucins
Polyps
Polysaccharides
Colon
Adenoma
2016
18 Citations (Scopus)

Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer

Krishn, S. R., Kaur, S., Smith, L. M., Johansson, S. L., Jain, M., Patel, A., Gautam, S. K., Hollingsworth, M. A., Mandel, U., Clausen, H., Lo, W. C., Fan, W. T. L., Manne, U. & Batra, S. K., May 1 2016, In : Cancer Letters. 374, 2, p. 304-314 11 p.

Research output: Contribution to journalArticle

Mucins
Early Detection of Cancer
Adenoma
Colonic Neoplasms
Polysaccharides
7 Citations (Scopus)

Polyplex-mediated inhibition of chemokine receptor CXCR4 and chromatin-remodeling enzyme NCOA3 impedes pancreatic cancer progression and metastasis

Wang, Y., Kumar, S., Rachagani, S., Sajja, B. R., Xie, Y., Hang, Y., Jain, M., Li, J., Boska, M. D., Batra, S. K. & Oupicky, D., Sep 1 2016, In : Biomaterials. 101, p. 108-120 13 p.

Research output: Contribution to journalArticle

Enzyme inhibition
Chromatin Assembly and Disassembly
Chemokine Receptors
Cytoplasmic and Nuclear Receptors
Pancreatic Neoplasms
2015

Erratum: MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway (Oncogene (2015) 34:2814 DOI:10.1038/onc.2015.116)

Macha, M. A., Rachagani, S., Pai, P., Gupta, S., Lydiatt, W. M., Smith, R. B., Johansson, S. L., Lele, S. M., Kakar, S. S., Farghaly, H., Lee, J. H., Meza, J. L., Ganti, A. K. P., Jain, M. & Batra, S. K., May 21 2015, In : Oncogene. 34, 21, p. 2814 1 p.

Research output: Contribution to journalArticle

Cell Aging
Oncogenes
Carcinoma, squamous cell of head and neck
4 Citations (Scopus)

Genetically engineered mucin mouse models for inflammation and cancer

Joshi, S., Kumar, S., Bafna, S., Rachagani, S., Wagner, K. U., Jain, M. & Batra, S. K., Dec 1 2015, In : Cancer and Metastasis Reviews. 34, 4, p. 593-609 17 p.

Research output: Contribution to journalArticle

Mucins
Inflammation
Neoplasms
Lubrication
Membranes
10 Citations (Scopus)

MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway

Macha, M. A., Rachagani, S., Pai, P., Gupta, S., Lydiatt, W. M., Smith, R. B., Johansson, S. L., Lele, S. M., Kakar, S. S., Lee, J. H., Meza, J. L., Ganti, A. K. P., Jain, M. & Batra, S. K., Mar 26 2015, In : Oncogene. 34, 13, p. 1698-1708 11 p.

Research output: Contribution to journalArticle

Cell Aging
Cyclin E
Histone Deacetylase 2
Up-Regulation
Down-Regulation
15 Citations (Scopus)

Mucin Expression in Endoscopic Ultrasound-Guided Fine-Needle Aspiration Specimens Is a Useful Prognostic Factor in Pancreatic Ductal Adenocarcinoma

Higashi, M., Yokoyama, S., Yamamoto, T., Goto, Y., Kitazono, I., Hiraki, T., Taguchi, H., Hashimoto, S., Fukukura, Y., Koriyama, C., Mataki, Y., Maemura, K., Shinchi, H., Jain, M., Batra, S. K. & Yonezawa, S., Jul 25 2015, In : Pancreas. 44, 5, p. 728-734 7 p.

Research output: Contribution to journalArticle

Endoscopic Ultrasound-Guided Fine Needle Aspiration
Mucins
Adenocarcinoma
Survival Analysis
Fine Needle Biopsy
15 Citations (Scopus)

Nano-immunoassay with improved performance for detection of cancer biomarkers

Krasnoslobodtsev, A. V., Torres, M. P., Kaur, S., Vlassiouk, I. V., Lipert, R. J., Jain, M., Batra, S. K. & Lyubchenko, Y. L., Jan 1 2015, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 11, 1, p. 167-173 7 p.

Research output: Contribution to journalArticle

Raman Spectrum Analysis
Tumor Biomarkers
Immunoassay
Raman scattering
Early Detection of Cancer
17 Citations (Scopus)

Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells

Lakshmanan, I., Seshacharyulu, P., Haridas, D., Rachagani, S., Gupta, S., Joshi, S., Guda, C., Yan, Y., Jain, M., Ganti, A. K. P., Palanimuthu Ponnusamy, M. & Batra, S. K., 2015, In : Oncotarget. 6, 25, p. 21085-21099 15 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Phenotype
Computational Biology
Phosphatidylinositol 3-Kinases
Immunoprecipitation
725 Citations (Scopus)

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Costa-Silva, B., Aiello, N. M., Ocean, A. J., Singh, S., Zhang, H., Thakur, B. K., Becker, A., Hoshino, A., Mark, M. T., Molina, H., Xiang, J., Zhang, T., Theilen, T. M., García-Santos, G., Williams, C., Ararso, Y., Huang, Y., Rodrigues, G., Shen, T. L., Labori, K. J. & 17 others, Lothe, I. M. B., Kure, E. H., Hernandez, J., Doussot, A., Ebbesen, S. H., Grandgenett, P. M., Hollingsworth, M. A., Jain, M., Mallya, K., Batra, S. K., Jarnagin, W. R., Schwartz, R. E., Matei, I., Peinado, H., Stanger, B. Z., Bromberg, J. & Lyden, D., Jun 1 2015, In : Nature Cell Biology. 17, 6, p. 816-826 11 p.

Research output: Contribution to journalArticle

Exosomes
Pancreatic Neoplasms
Adenocarcinoma
Liver
Neoplasm Metastasis
1097 Citations (Scopus)

Tumour exosome integrins determine organotropic metastasis

Hoshino, A., Costa-Silva, B., Shen, T. L., Rodrigues, G., Hashimoto, A., Tesic Mark, M., Molina, H., Kohsaka, S., Di Giannatale, A., Ceder, S., Singh, S., Williams, C., Soplop, N., Uryu, K., Pharmer, L., King, T., Bojmar, L., Davies, A. E., Ararso, Y., Zhang, T. & 34 others, Zhang, H., Hernandez, J., Weiss, J. M., Dumont-Cole, V. D., Kramer, K., Wexler, L. H., Narendran, A., Schwartz, G. K., Healey, J. H., Sandstrom, P., Jørgen Labori, K., Kure, E. H., Grandgenett, P. M., Hollingsworth, M. A., De Sousa, M., Kaur, S., Jain, M., Mallya, K., Batra, S. K., Jarnagin, W. R., Brady, M. S., Fodstad, O., Muller, V., Pantel, K., Minn, A. J., Bissell, M. J., Garcia, B. A., Kang, Y., Rajasekhar, V. K., Ghajar, C. M., Matei, I., Peinado, H., Bromberg, J. & Lyden, D., Nov 19 2015, In : Nature. 527, 7578, p. 329-335 7 p.

Research output: Contribution to journalArticle

Exosomes
Integrins
Neoplasm Metastasis
Lung
Neoplasms
2014
35 Citations (Scopus)

MicroRNAs (miRNAs) as biomarker(s) for prognosis and diagnosis of gastrointestinal (GI) cancers

Macha, M. A., Seshacharyulu, P., Krishn, S. R., Pai, P., Rachagani, S., Jain, M. & Batra, S. K., Jan 1 2014, In : Current Pharmaceutical Design. 20, 33, p. 5287-5297 11 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
MicroRNAs
Biomarkers
Neoplasms
Biological Phenomena
28 Citations (Scopus)

Mucins in lung Cancer: Diagnostic, Prognostic and Therapeutic Implications

Lakshmanan, I., Palanimuthu Ponnusamy, M., Macha, M. A., Haridas, D., Majhi, P. D., Kaur, S., Jain, M., Batra, S. K. & Ganti, A. K. P., Oct 14 2014, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Mucins
Lung Neoplasms
Therapeutics
Neoplasms
Receptor Protein-Tyrosine Kinases
11 Citations (Scopus)
Mucins
Pancreatic Neoplasms
Up-Regulation
Chromatin
Ubiquitin C
21 Citations (Scopus)

Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages

Kumar, S., Torres, M. P., Kaur, S., Rachagani, S., Joshi, S., Johansson, S. L., Momi, N., Baine, M. J., Cutucache, C. E., Smith, L. M., Wyatt, T. A., Jain, M., Joshi, S. S. & Batra, S. K., Jun 9 2014, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Smoke
Smoking
Macrophages
Metaplasia
27 Citations (Scopus)

Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation.

Souchek, J. J., Baine, M. J., Lin, C., Rachagani, S., Gupta, S., Kaur, S., Lester, K., Zheng, D., Chen, S., Smith, L. M., Lazenby, A. J., Johansson, S. L., Jain, M. & Batra, S. K., Jan 1 2014, In : British journal of cancer. 111, 6, p. 1139-1149 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Cholesterol
Radiation
Geranyltranstransferase
zoledronic acid
2013
38 Citations (Scopus)
Pancreatic Neoplasms
Apoptosis
pregna-4,17-diene-3,16-dione
Neoplasms
Annexin A5
32 Citations (Scopus)

MUC4 Overexpression Augments Cell Migration and Metastasis through EGFR Family Proteins in Triple Negative Breast Cancer Cells

Mukhopadhyay, P., Lakshmanan, I., Palanimuthu Ponnusamy, M., Chakraborty, S., Jain, M., Pai, P., Smith, L. M., Lele, S. M. & Batra, S. K., Feb 11 2013, In : PloS one. 8, 2, e54455.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
cell movement
metastasis
breast neoplasms
Cell Movement
9 Citations (Scopus)

Neutrophil gelatinase-associated lipocalin, macrophage inhibitory cytokine 1, and carbohydrate antigen 19-9 in pancreatic juice: Pathobiologic implications in diagnosing benign and malignant disease of the pancreas

Kaur, S., Baine, M. J., Guha, S., Ochi, N., Chakraborty, S., Mallya, K., Thomas, C., Crook, J., Wallace, M. B., Woodward, T. A., Jain, M., Singh, S., Sasson, A. R., Skinner, V., Raimondo, M. & Batra, S. K., Apr 1 2013, In : Pancreas. 42, 3, p. 494-501 8 p.

Research output: Contribution to journalArticle

Growth Differentiation Factor 15
Pancreatic Juice
Pancreas
Carbohydrates
Antigens
20 Citations (Scopus)

Pathobiological implications of MUC4 in non-small-cell lung cancer

Majhi, P. D., Lakshmanan, I., Palanimuthu Ponnusamy, M., Jain, M., Das, S., Kaur, S., Shimizu, S. T., West, W. W., Johansson, S. L., Smith, L. M., Yu, F., Rolle, C. E., Sharma, P., Carey, G. B., Batra, S. K. & Ganti, A. K. P., Jan 1 2013, In : Journal of Thoracic Oncology. 8, 4, p. 398-407 10 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Lung Neoplasms
Neoplasms
Cyclin E
Survival
31 Citations (Scopus)

Potentials of Plasma NGAL and MIC-1 as Biomarker(s) in the Diagnosis of Lethal Pancreatic Cancer

Kaur, S., Chakraborty, S., Baine, M. J., Mallya, K., Smith, L. M., Sasson, A., Brand, R., Guha, S., Jain, M., Wittel, U., Singh, S. & Batra, S. K., Feb 1 2013, In : PloS one. 8, 2, e55171.

Research output: Contribution to journalArticle

Growth Differentiation Factor 15
Lipocalins
pancreatic neoplasms
Gelatinases
Biomarkers
2012
46 Citations (Scopus)
Receptor, Fibroblast Growth Factor, Type 1
Pancreatic Neoplasms
Cadherins
Down-Regulation
Neoplasm Metastasis
36 Citations (Scopus)

Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: Potential implications for diagnosis and therapy

Rachagani, S., Torres, M. P., Kumar, S., Haridas, D., Baine, M., Macha, M. A., Kaur, S., Palanimuthu Ponnusamy, M., Dey, P., Seshacharyulu, P., Johansson, S. L., Jain, M., Wagner, K. U. & Batra, S. K., Oct 30 2012, In : Journal of Hematology and Oncology. 5, 68.

Research output: Contribution to journalArticle

Mucins
Pancreatic Neoplasms
Therapeutics
Pancreas
Neoplasms
2011
50 Citations (Scopus)
Cadherins
Pancreatic Neoplasms
Alleles
Neoplasm Metastasis
Proto-Oncogenes
142 Citations (Scopus)

Detection of the potential pancreatic cancer marker MUC4 in serum using surface-enhanced Raman scattering

Wang, G., Lipert, R. J., Jain, M., Kaur, S., Chakraboty, S., Torres, M. P., Batra, S. K., Brand, R. E. & Porter, M. D., Apr 1 2011, In : Analytical Chemistry. 83, 7, p. 2554-2561 8 p.

Research output: Contribution to journalArticle

Raman scattering
Assays
Immunosorbents
Mucins
Proteins
9 Citations (Scopus)

Monoclonal antibodies recognizing the non-tandem repeat regions of the human mucin MUC4 in pancreatic cancer

Jain, M., Venkatraman, G., Moniaux, N., Kaur, S., Kumar, S., Chakraborty, S., Varshney, G. C. & Batra, S. K., Aug 23 2011, In : PloS one. 6, 8, e23344.

Research output: Contribution to journalArticle

pancreatic neoplasms
mucins
Mucins
Pancreatic Neoplasms
monoclonal antibodies
2010
107 Citations (Scopus)

MUC4 mucin-induced epithelial to mesenchymal transition: A novel mechanism for metastasis of human ovarian cancer cells

Palanimuthu Ponnusamy, M., Lakshmanan, I., Jain, M., Das, S., Chakraborty, S., Dey, P. & Batra, S. K., Oct 21 2010, In : Oncogene. 29, 42, p. 5741-5754 14 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Mucins
Ovarian Neoplasms
Neoplasm Metastasis
Cadherins
2009
14 Citations (Scopus)

Upregulation of MUC4 in cervical squamous cell carcinoma: Pathologic significance

Munro, E. G., Jain, M., Oliva, E., Kamal, N., Lele, S. M., Lynch, M. P., Guo, L., Fu, K., Sharma, P., Remmenga, S. W., Growdon, W. B., Davis, J. S., Rueda, B. R. & Batra, S. K., Mar 1 2009, In : International Journal of Gynecological Pathology. 28, 2, p. 127-133 7 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Up-Regulation
Staining and Labeling
Epithelium
Cervical Intraepithelial Neoplasia
2008
73 Citations (Scopus)

A physiologically based pharmacokinetic (PBPK) model to characterize and predict the disposition of monoclonal antibody CC49 and its single chain Fv constructs

Davda, J. P., Jain, M., Batra, S. K., Gwilt, P. R. & Robinson, D. H., Mar 1 2008, In : International Immunopharmacology. 8, 3, p. 401-413 13 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Pharmacokinetics
Monoclonal Antibodies
Immunoglobulin G
Neoplasms
114 Citations (Scopus)

Early diagnosis of pancreatic cancer: Neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neoplasia

Moniaux, N., Chakraborty, S., Yalniz, M., Gonzalez, J., Shostrom, V. K., Standop, J., Lele, S. M., Ouellette, M. M., Pour, P. M., Sasson, A. R., Brand, R. E., Hollingsworth, M. A., Jain, M. & Batra, S. K., May 6 2008, In : British journal of cancer. 98, 9, p. 1540-1547 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Early Detection of Cancer
Neoplasms
Pancreatitis
Pancreas
51 Citations (Scopus)

MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells

Palanimuthu Ponnusamy, M., Singh, A. P., Jain, M., Chakraborty, S., Moniaux, N. & Batra, S. K., Aug 5 2008, In : British journal of cancer. 99, 3, p. 520-526 7 p.

Research output: Contribution to journalArticle

Mucins
Ovarian Neoplasms
Actins
Focal Adhesion Protein-Tyrosine Kinases
Pseudopodia
2007
22 Citations (Scopus)

Expression of TAG-72 in ovarian cancer and its correlation with tumor stage and patient prognosis

Palanimuthu Ponnusamy, M., Venkatraman, G., Singh, A. P., Chauhan, S. C., Johansson, S. L., Jain, M., Smith, L. M., Davis, J. S., Remmenga, S. W. & Batra, S. K., Jun 28 2007, In : Cancer Letters. 251, 2, p. 247-257 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Monoclonal Antibodies
tumor-associated antigen 72
Staining and Labeling
2006
95 Citations (Scopus)

Aberrant expression of MUC4 in ovarian carcinoma: Diagnostic significance alone and in combination with MUC1 and MUC16 (CA125)

Chauhan, S. C., Singh, A. P., Ruiz, F., Johansson, S. L., Jain, M., Smith, L. M., Moniaux, N. & Batra, S. K., Oct 21 2006, In : Modern Pathology. 19, 10, p. 1386-1394 9 p.

Research output: Contribution to journalArticle

Mucins
Carcinoma
Neoplasms
Survival
Incidence
2005
12 Citations (Scopus)

Engineering and characterization of a divalent single-chain Fv angiotensin II fusion construct of the monoclonal antibody CC49

Wittel, U. A., Jain, M., Goel, A., Baranowska-Kortylewicz, J., Kurizaki, T., Chauhan, S. C., Agrawal, D. K., Colcher, D. & Batra, S. K., Apr 1 2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 168-176 9 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Angiotensin II
Fusion reactions
Monoclonal Antibodies
Tumors
70 Citations (Scopus)

Penetratin improves tumor retention of single-chain antibodies: A novel step toward optimization of radioimmunotherapy of solid tumors

Jain, M., Chauhan, S. C., Singh, A. P., Venkatraman, G., Colcher, D. & Batra, S. K., Sep 1 2005, In : Cancer Research. 65, 17, p. 7840-7846 7 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Single-Chain Antibodies
Trans-Activators
Neoplasms
Pharmacokinetics
28 Citations (Scopus)

Pharmacokinetics and biodistribution of 177Lu-labeled multivalent single-chain Fv construct of the pancarcinoma monoclonal antibody CC49

Chauhan, S. C., Jain, M., Moore, E. D., Wittel, U. A., Li, J., Gwilt, P. R., Colcher, D. & Batra, S. K., Mar 1 2005, In : European Journal of Nuclear Medicine and Molecular Imaging. 32, 3, p. 264-273 10 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Pharmacokinetics
Immunoglobulin G
Monoclonal Antibodies
Pentetic Acid
33 Citations (Scopus)

The in vivo characteristics of genetically engineered divalent and tetravalent single-chain antibody constructs

Wittel, U. A., Jain, M., Goel, A., Chauhan, S. C., Colcher, D. & Batra, S. K., Jan 1 2005, In : Nuclear Medicine and Biology. 32, 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Immunoglobulin Fragments
Half-Life
Pharmacokinetics
Immunoglobulin G
2004
66 Citations (Scopus)

Generation and Characterization of Anti-MUC4 Monoclonal Antibodies Reactive with Normal and Cancer Cells in Humans

Moniaux, N., Varshney, G. C., Chauhan, S. C., Copin, M. C., Jain, M., Wittel, U. A., Andrianifahanana, M., Aubert, J. P. & Batra, S. K., Jan 1 2004, In : Journal of Histochemistry and Cytochemistry. 52, 2, p. 253-261 9 p.

Research output: Contribution to journalArticle

Open Access
Tandem Repeat Sequences
Monoclonal Antibodies
Mucins
Peptides
Clone Cells