Lawrence J Parkhurst, PhD

Professor

  • 2062 Citations
  • 25 h-Index
1963 …2013
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Fingerprint Dive into the research topics where Lawrence J Parkhurst is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Hemoglobins Medicine & Life Sciences
Carbon Monoxide Medicine & Life Sciences
Kinetics Chemical Compounds
TATA-Box Binding Protein Medicine & Life Sciences
Oxygen Chemical Compounds
Heme Chemical Compounds
DNA Medicine & Life Sciences
Carps Medicine & Life Sciences

Projects 1968 2009

TATA-Box Binding Protein
Transcription Factor TFIIB
DNA
TATA Box
Transcription Factor TFIIA
Myoglobin
Hemoglobins
Kinetics
Proteins
Ligands
Erythrocytes
Proteins
Virus Diseases
Messenger RNA
Complementary DNA
Myoglobin
Hemoglobins
Kinetics
Ligands
Oxygen

Research Output 1963 2013

  • 2062 Citations
  • 25 h-Index
  • 79 Article
  • 2 Letter
  • 2 Review article
16 Citations (Scopus)

A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A

Glanzer, J. G., Carnes, K. A., Soto, P., Liu, S., Parkhurst, L. J. & Oakley, G. G., Feb 1 2013, In : Nucleic acids research. 41, 3, p. 2047-2059 13 p.

Research output: Contribution to journalArticle

Replication Protein A
Transcriptional Activation
Tryptophan
DNA Repair
DNA Damage
16 Citations (Scopus)

Spectroscopic properties of fluorescein and rhodamine dyes attached to DNA

Delgadillo, R. F. & Parkhurst, L. J., Mar 1 2010, In : Photochemistry and Photobiology. 86, 2, p. 261-272 12 p.

Research output: Contribution to journalArticle

Rhodamines
rhodamine
Fluorescein
Coloring Agents
deoxyribonucleic acid
30 Citations (Scopus)

The TATA-binding protein core domain in solution variably bends TATA sequences via a three-step binding mechanism

Delgadillo, R. F., Whittington, J. E., Parkhurst, L. K. & Parkhurst, L. J., Mar 3 2009, In : Biochemistry. 48, 8, p. 1801-1809 9 p.

Research output: Contribution to journalArticle

TATA-Box Binding Protein
DNA
Yeast
Yeasts
Protein Domains
17 Citations (Scopus)

TATA-binding protein recognition and bending of a consensus promoter are protein species dependent

Whittington, J. E., Delgadillo, R. F., Attebury, T. J., Parkhurst, L. K., Daugherty, M. A. & Parkhurst, L. J., Jul 8 2008, In : Biochemistry. 47, 27, p. 7264-7273 10 p.

Research output: Contribution to journalArticle

TATA-Box Binding Protein
Consensus
Proteins
TATA Box
Fluorescence Polarization
20 Citations (Scopus)

Changes in DNA bending and flexing due to tethered cations detected by fluorescence resonance energy transfer

Williams, S. L., Parkhurst, L. K. & Parkhurst, L. J., Mar 20 2006, In : Nucleic acids research. 34, 3, p. 1028-1035 8 p.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Energy Transfer
Cations
DNA
Static Electricity