Kishor K Bhakat, PhD

Associate Professor

  • 2430 Citations
  • 26 h-Index
19942019
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  • 3 Similar Profiles
Acetylation Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
DNA-(Apurinic or Apyrimidinic Site) Lyase Medicine & Life Sciences
Endonucleases Medicine & Life Sciences
DNA Glycosylases Medicine & Life Sciences
Repair Chemical Compounds
Genes Chemical Compounds
DNA Damage Medicine & Life Sciences

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Projects 2011 2016

Acetylation
DNA Repair
Apoptosis
DNA
Cell Survival

Research Output 1994 2019

  • 2430 Citations
  • 26 h-Index
  • 41 Article
  • 2 Review article
  • 1 Chapter

Biochemical and cellular assays to assess the effects of acetylation on base excision repair enzymes

Roychoudhury, S., Pramanik, S., Harris, H. L. & Bhakat, K. K., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 191-206 16 p. (Methods in Molecular Biology; vol. 1983).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acetylation
DNA Repair
Enzymes
Proteins
DNA Damage
2 Citations (Scopus)

Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress

Sengupta, S., Yang, C., Hegde, M. L., Hegde, P. M., Mitra, J., Pandey, A., Dutta, A., Datarwala, A. T., Bhakat, K. K. & Mitra, S., Jun 1 2018, In : DNA Repair. 66-67, p. 1-10 10 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Acetylation
Oxidative stress
Human Genome
Chromatin

Suppression of STAT3 NH2-terminal domain chemosensitizes medulloblastoma cells by activation of protein inhibitor of activated STAT3 via de-repression by microRNA-21

Ray, S., Coulter, D. W., Gray, S. D., Sughroue, J. A., Roychoudhury, S., Mcintyre, E. M., Chaturvedi, N. K., Bhakat, K. K., Joshi, S. S., McGuire, T. R. & Sharp, J. G., Jan 1 2018, (Accepted/In press) In : Molecular Carcinogenesis.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Medulloblastoma
MicroRNAs
Proteins
Down-Regulation
13 Citations (Scopus)

Human apurinic/apyrimidinic endonuclease (APE1) is acetylated at DNA damage sites in chromatin, and acetylation modulates its DNA repair activity

Roychoudhury, S., Nath, S., Song, H., Hegde, M. L., Bellot, L. J., Mantha, A. K., Sengupta, S., Ray, S., Natarajan, A. & Bhakat, K. K., Jan 1 2017, In : Molecular and cellular biology. 37, 6, e00401-16.

Research output: Contribution to journalArticle

DNA-(Apurinic or Apyrimidinic Site) Lyase
Acetylation
DNA Repair
DNA Damage
Chromatin
5 Citations (Scopus)

The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression

Nath, S., Roychoudhury, S., Kling, M. J., Song, H., Biswas, P., Shukla, A., Band, H., Joshi, S. S. & Bhakat, K. K., Nov 1 2017, In : Cellular Signalling. 39, p. 18-31 14 p.

Research output: Contribution to journalArticle

Endonucleases
DNA Repair
DNA Damage
Interleukin-6
Proteins