• 285 Citations
  • 10 h-Index
19992019
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Fingerprint Dive into the research topics where Kate Hyde is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Leukemia Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Core Binding Factors Medicine & Life Sciences
Chromosomes, Human, Pair 16 Medicine & Life Sciences
Core Binding Factor beta Subunit Medicine & Life Sciences
Genes Chemical Compounds
Gene Fusion Medicine & Life Sciences
Chorionic Gonadotropin Medicine & Life Sciences

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Projects 2013 2016

Acute Myeloid Leukemia
Gene Fusion
Gene Expression
Leukemia
Research Personnel

Research Output 1999 2019

HDAC1 is a required cofactor of CBFb-SMMHC and a potential therapeutic target in inversion 16 acute myeloid leukemia

Richter, L. E., Wang, Y., Becker, M. E., Coburn, R. A., Williams, J. T., Amador, C. & Hyde, R. K., Jun 1 2019, In : Molecular Cancer Research. 17, 6, p. 1241-1252 12 p.

Research output: Contribution to journalArticle

Histone Deacetylase 1
Acute Myeloid Leukemia
Core Binding Factor beta Subunit
Chromosomes, Human, Pair 16
Histone Deacetylase Inhibitors
2 Citations (Scopus)

IL1RL1 is dynamically expressed on Cbfb-MYH11 + leukemia stem cells and promotes cell survival

Wang, Y., Richter, L., Becker, M., Amador, C. & Hyde, R. K., Dec 1 2019, In : Scientific Reports. 9, 1, 1729.

Research output: Contribution to journalArticle

Open Access
Cell Survival
Leukemia
Stem Cells
Myeloid Cells
Acute Myeloid Leukemia
1 Citation (Scopus)

Use of polymeric CXCR4 inhibitors as siRNA delivery vehicles for the treatment of acute myeloid leukemia

Wang, Y., Xie, Y., Williams, J., Hang, Y., Richter, L., Becker, M., Amador, C., Oupicky, D. & Hyde, R. K., Jan 1 2019, In : Cancer Gene Therapy.

Research output: Contribution to journalArticle

CXCR4 Receptors
Acute Myeloid Leukemia
Small Interfering RNA
Leukemia
Oncogenes
4 Citations (Scopus)

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

Zhen, T., Kwon, E. M., Zhao, L., Hsu, J., Hyde, R. K., Lu, Y., Alemu, L., Speck, N. A. & Liu, P. P., Nov 30 2017, In : Blood. 130, 22, p. 2431-2442 12 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Genes
Gene Fusion
Hematopoietic Stem Cells
Leukemia
4 Citations (Scopus)

RUNX1 and CBFβ mutations and activities of their wild-type alleles in AML

Hyde, R. K., Liu, P. & Friedman, A. D., 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 962. p. 265-282 18 p. (Advances in Experimental Medicine and Biology; vol. 962).

Research output: Chapter in Book/Report/Conference proceedingChapter

Myelodysplastic-Myeloproliferative Diseases
Leukemia
Alleles
Mutation
Germ-Line Mutation