John Y Um, MD

Associate Professor

  • 404 Citations
  • 9 h-Index
19952019
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Research Output 1995 2019

  • 404 Citations
  • 9 h-Index
  • 23 Article
  • 2 Letter
  • 1 Comment/debate
  • 1 Review article
2019
52 Citations (Scopus)

A fully magnetically levitated left ventricular assist device - Final report

Mehra, M. R., Uriel, N., Naka, Y., Cleveland, J. C., Yuzefpolskaya, M., Salerno, C. T., Walsh, M. N., Milano, C. A., Patel, C. B., Hutchins, S. W., Ransom, J., Ewald, G. A., Itoh, A., Raval, N. Y., Silvestry, S. C., Cogswell, R., John, R., Bhimaraj, A., Bruckner, B. A., Lowes, B. D. & 20 others, Um, J. Y., Jeevanandam, V., Sayer, G., Mangi, A. A., Molina, E. J., Sheikh, F., Aaronson, K., Pagani, F. D., Cotts, W. G., Tatooles, A. J., Babu, A., Chomsky, D., Katz, J. N., Tessmann, P. B., Dean, D., Krishnamoorthy, A., Chuang, J., Topuria, I., Sood, P. & Goldstein, D. J., Apr 25 2019, In : New England Journal of Medicine. 380, 17, p. 1618-1627 10 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Stroke
Reoperation
Equipment and Supplies
Heart Failure
Extracorporeal Membrane Oxygenation
Heart-Assist Devices
Survival
Confidence Intervals
Interleukin-11

Elevated Heart Rate Following Heart Transplantation Is Associated With Increased Graft Vasculopathy and Mortality

Liebo, M., Newman, J., Joshi, A., Lowes, B. D., Peled-Potashnik, Y., Basha, H. I., Zolty, R., Um, J. Y., McGee, E., Heroux, A. & Raichlin, E., Apr 2019, In : Journal of Cardiac Failure. 25, 4, p. 249-256 8 p.

Research output: Contribution to journalArticle

Heart Transplantation
Heart Rate
Transplants
Mortality
Allografts
2 Citations (Scopus)

Molecular discoveries and treatment strategies by direct reprogramming in cardiac regeneration

Werner, J. H., Rosenberg, J. H., Um, J. Y., Moulton, M. J. & Agrawal, D. K., Jan 2019, In : Translational Research. 203, p. 73-87 15 p.

Research output: Contribution to journalReview article

Cardiac Myocytes
Regeneration
Fibroblasts
Tissue
MicroRNAs
1 Citation (Scopus)

Recurrent pump thrombosis is common after axial continuous-flow left ventricular assist device exchange

Urban, M., Um, J., Moulton, M., Stoller, D., Zolty, R., Lowes, B., Macdonald, C., McCain, N. & Siddique, A., Jan 1 2019, (Accepted/In press) In : International Journal of Artificial Organs.

Research output: Contribution to journalArticle

Left ventricular assist devices
Heart-Assist Devices
Thrombosis
Pumps
Survival

The effect of donor alcohol abuse on outcomes following heart transplantation

Newman, J., Liebo, M., Lowes, B. D., Ilias Basha, H., Peled, Y., Cendrowski, E., Zolty, R., Douglas, D., Um, J. Y., McGee, E., Heroux, A. & Raichlin, E., Feb 1 2019, In : Clinical Transplantation. 33, 2, e13461.

Research output: Contribution to journalArticle

Heart Transplantation
Alcoholism
Tissue Donors
Allografts
Alcoholics

Ventricular Assist Device Driveline Dressing-Change Protocols: A Need for Standardization. A Report from the SimVAD Investigators

Wilcox, J. E., Cameron, K. A., Harap, R. S., Shanklin, K. L., Grady, K. L., Cohen, E. R., Abicht, T. O., Adler, E. D., Alexy, T., Alonso, W., Beckman, J., Bjelkengren, J., Cagliostro, B., Cogswell, R., Colombo, P. C., Cotts, W., Haglund, N. A., Haverstick, S., Kiernan, M. S., Lampert, B. & 13 others, LeMond, L. M., Lee, S., Lerg, G., Lindenfeld, J., Mahr, C., Meehan, K., Pagani, F. D., Pan, S., Pavone, J., Um, J., Yancy, C. W., Thinh, D. & Barsuk, J. H., Aug 2019, In : Journal of Cardiac Failure. 25, 8, p. 695-697 3 p.

Research output: Contribution to journalLetter

Heart-Assist Devices
Bandages
Research Personnel
1 Citation (Scopus)
Open Access
Extracorporeal Membrane Oxygenation
Heart Transplantation
Mortality
Transplants
Waiting Lists
2018
3 Citations (Scopus)

Depression and anxiety in patients undergoing left ventricular assist device implantation

Lundgren, S., Poon, C. Y. M., Selim, A., Lowes, B. D., Zolty, R., Burdorf, A., Potashnik-Peled, Y., Moulton, M. J., Um, J. Y. & Raichlin, E., Nov 1 2018, In : International Journal of Artificial Organs. 41, 2, p. 76-83 8 p.

Research output: Contribution to journalArticle

Left ventricular assist devices
Heart-Assist Devices
Anxiety
Depression
Opioid-Related Disorders
7 Citations (Scopus)

Do Psychosocial Factors Have Any Impact on Outcomes After Left Ventricular Assist Device Implantation?

Lundgren, S., Lowes, B. D., Zolty, R., Burdorf, A., Raichlin, E., Um, J. Y. & Poon, C., Jul 1 2018, In : ASAIO journal (American Society for Artificial Internal Organs : 1992). 64, 4, p. e43-e47

Research output: Contribution to journalArticle

Left ventricular assist devices
Heart-Assist Devices
Psychology
Depression
Mortality
2017
1 Citation (Scopus)

Effect of diltiazem on exercise capacity after heart transplantation

Varnado, S., Peled-Potashnik, Y., Huntsberry, A., Lowes, B. D., Zolty, R., Burdorf, A., Lyden, E. R., Moulton, M. J., Um, J. Y. & Raichlin, E., Aug 2017, In : Clinical Transplantation. 31, 8, e12997.

Research output: Contribution to journalArticle

Diltiazem
Heart Transplantation
Exercise
Sinus Tachycardia
Heart Rate
3 Citations (Scopus)

Sinus tachycardia is associated with impaired exercise tolerance following heart transplantation

Peled, Y., Varnado, S., Lowes, B. D., Zolty, R., Lyden, E. R., Moulton, M. J., Um, J. Y. & Raichlin, E., May 2017, In : Clinical Transplantation. 31, 5, e12946.

Research output: Contribution to journalArticle

Sinus Tachycardia
Exercise Tolerance
Heart Transplantation
Exercise
Heart Rate
2016

Corrigendum: Inhaled Milrinone after Left Ventricular Assist Device Implantation (Journal of Cardiac Failure (2015) 21:10 (792-797) doi:10.1016/j.cardfail.2015.04.011)

Haglund, N. A., Burdorf, A., Jones, T., Shostrom, V., Um, J. Y., Ryan, T., Shillcutt, S. K., Fischer, P., Cox, Z. L., Raichlin, E., Anderson, D. R., Lowes, B. D. & Dumitru, I., Mar 1 2016, In : Journal of Cardiac Failure. 22, 3, 1 p.

Research output: Contribution to journalComment/debate

Milrinone
Heart-Assist Devices
Heart Failure
corrigendum
12 Citations (Scopus)

Outcomes in patients with severe preexisting renal dysfunction after continuous-flow left ventricular assist device implantation

Raichlin, E., Baibhav, B., Lowes, B. D., Zolty, R., Lyden, E. R. R., Vongooru, H. R. R., Siddique, A., Moulton, M. J. & Um, J. Y., Jan 1 2016, In : ASAIO Journal. 62, 3, p. 261-267 7 p.

Research output: Contribution to journalArticle

Left ventricular assist devices
Heart-Assist Devices
Glomerular Filtration Rate
Kidney
Heart Transplantation
4 Citations (Scopus)

Targeted myocardial gene expression in failing hearts by RNA sequencing

Dhar, K., Moulton, A. M., Rome, E., Qiu, F., Kittrell, J., Raichlin, E., Zolty, R., Um, J. Y., Moulton, M. J., Basma, H. E., Anderson, D. R., Eudy, J. D. & Lowes, B. D., Nov 25 2016, In : Journal of Translational Medicine. 14, 1, 327.

Research output: Contribution to journalArticle

Heart-Assist Devices
Gene expression
Left ventricular assist devices
RNA
Genes
2015
1 Citation (Scopus)

Cardiac Assist Devices and Hemodialysis Catheter Procedures - What Do the Nephrologists Need to Know?

Florescu, M. C., Sacks, A. R. & Um, J. Y., Nov 1 2015, In : Seminars in Dialysis. 28, 6, p. 670-675 6 p.

Research output: Contribution to journalArticle

Renal Dialysis
Catheters
Dialysis
Equipment and Supplies
Artificial Heart
14 Citations (Scopus)

Inhaled milrinone after left ventricular assist device implantation

Haglund, N. A., Burdorf, A., Jones, T., Shostrom, V., Um, J. Y., Ryan, T., Shillcutt, S. K., Fischer, P., Cox, Z. L., Raichlin, E., Lowes, B. D. & Dumitru, I., Oct 1 2015, In : Journal of Cardiac Failure. 21, 10, p. 792-797 6 p.

Research output: Contribution to journalArticle

Milrinone
Heart-Assist Devices
Pharmacokinetics
Costs and Cost Analysis
Hypotension
2014
6 Citations (Scopus)

Combined heart and liver transplantation against positive cross-match for patient with hypoplastic left heart syndrome

Raichlin, E., Um, J. Y., Duncan, K. F., Dumitru, I., Lowes, B. D., Moulton, M. J., Gebhart, C. L., Grant, W. J. & Hammel, J. M., Jan 1 2014, In : Transplantation. 98, 12, p. e100-e102

Research output: Contribution to journalLetter

Hypoplastic Left Heart Syndrome
Fontan Procedure
Histocompatibility Testing
Heart Transplantation
Human Herpesvirus 4
Heart-Assist Devices
Transesophageal Echocardiography
25 Citations (Scopus)

Unique antibody responses to malondialdehyde-acetaldehyde (MAA)-protein adducts predict coronary artery disease

Anderson, D. R., Duryee, M. J., Shurmur, S. W., Um, J. Y., Bussey, W. D., Hunter, C. D., Garvin, R. P., Sayles, H. R., Mikuls, T. R., Klassen, L. W. & Thiele, G. M., Sep 1 2014, In : PloS one. 9, 9, 0107440.

Research output: Contribution to journalArticle

Acetaldehyde
acetaldehyde
Malondialdehyde
malondialdehyde
Antibody Formation
2013
1 Citation (Scopus)

Cytomegalovirus reactivation and colitis after left ventricular assist device placement

Sandkovsky, U., Florescu, D. F., Um, J. Y., Raichlin, E., Lowes, B. D., Kapalis, M., Hewlett, A., Duncan, K. F., Ryan, T., DiMaio, D. J., Wedel, W. & Kalil, A. C., May 1 2013, In : International Journal of Infectious Diseases. 17, 5, p. e348-e351

Research output: Contribution to journalArticle

Heart-Assist Devices
Colitis
Cytomegalovirus
Hemorrhage
2012
Transposition of Great Vessels
Mustard Plant
Heart Transplantation
Pulmonary Artery
Heart-Assist Devices
2010
58 Citations (Scopus)

Plasmapheresis and heparin reexposure as a management strategy for cardiac surgical patients with heparin-induced thrombocytopenia

Welsby, I. J., Um, J., Milano, C. A., Ortel, T. L. & Arepally, G., Jan 2010, In : Anesthesia and analgesia. 110, 1, p. 30-35 6 p.

Research output: Contribution to journalArticle

Plasmapheresis
Thrombocytopenia
Platelet Factor 4
Heparin
Thoracic Surgery
2004
67 Citations (Scopus)

Effects of drotrecogin alfa (activated) in human endotoxemia.

Kalil, A. C., Coyle, S. M., Um, J. Y., LaRosa, S. P., Turlo, M. A., Calvano, S. E., Sundin, D. P., Nelson, D. R. & Lowry, S. F., Mar 2004, In : Shock (Augusta, Ga.). 21, 3, p. 222-229 8 p.

Research output: Contribution to journalArticle

Endotoxemia
Endotoxins
Sepsis
Clinical Trials
Phase III Clinical Trials
2003
29 Citations (Scopus)

Influence of the TNF-α and TNF-β polymorphisms upon infectious risk and outcome in surgical intensive care patients

Calvano, J. E., Um, J. Y., Agnese, D. M., Hahm, S. J., Kumar, A., Coyle, S. M., Calvano, S. E. & Lowry, S. F., Jan 1 2003, In : Surgical Infections. 4, 2, p. 163-169 7 p.

Research output: Contribution to journalArticle

Critical Care
Tumor Necrosis Factor-alpha
Septic Shock
Alleles
Sepsis
61 Citations (Scopus)

Modulation of the lipopolysaccharide receptor complex (CD14, TLR4, MD-2) and toll-like receptor 2 in systemic inflammatory response syndrome-positive patients with and without infection: relationship to tolerance.

Calvano, J. E., Agnese, D. M., Um, J. Y., Goshima, M., Singhal, R., Coyle, S. M., Reddell, M. T., Kumar, A., Calvano, S. E. & Lowry, S. F., Nov 2003, In : Shock (Augusta, Ga.). 20, 5, p. 415-419 5 p.

Research output: Contribution to journalArticle

CD14 Antigens
Toll-Like Receptor 2
Systemic Inflammatory Response Syndrome
Lipopolysaccharides
Monocytes
1995
56 Citations (Scopus)

Isolation of mammalian cell mutants that are X-ray sensitive, impaired in DNA double-strand break repair and defective for V(D)J recombination

Lee, S. E., Pulaski, C. R., He, D. M., Benjamin, D. M., Voss, M., Um, J. & Hendrickson, E. A., May 1995, In : Mutation Research-DNA Repair. 336, 3, p. 279-291 13 p.

Research output: Contribution to journalArticle

V(D)J Recombination
Double-Stranded DNA Breaks
Cell Separation
Repair
Cells