Jean L Grem, MD

Professor

  • 7610 Citations
  • 49 h-Index
1985 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1985 2019

2019
Nelfinavir
Radiosurgery
gemcitabine
Adenocarcinoma
Antigens
1 Citation (Scopus)
Nelfinavir
Radiosurgery
gemcitabine
Adenocarcinoma
Survival

Small bowel adenocarcinoma, version 1.2020

Benson, A. B., Venook, A. P., Al-Hawary, M. M., Arain, M. A., Chen, Y. J., Ciombor, K. K., Cohen, S. A., Cooper, H. S., Deming, D. A., Garrido-Laguna, I., Grem, J. L., Hoffe, S. E., Hubbard, J., Hunt, S., Kamel, A., Kirilcuk, N., Krishnamurthi, S., Messersmith, W. A., Meyerhardt, J., Miller, E. D. & 17 others, Mulcahy, M. F., Steven Nurkin, Md, Ms, N. M. M., Overman, M. J., Parikh, A., Patel, H., Pedersen, K. S., Saltz, L. B., Schneider, C., Shibata, D., Skibber, J. M., Sofocleous, C. T., Stoffel, E. M., Stotsky-Himelfarb, E., Willett, C. G., Johnson-Chilla, A., Gregory, K. M. & Gurski, L. A., Jan 1 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 9, p. 1109-1133 25 p.

Research output: Contribution to journalReview article

Open Access
Adenocarcinoma
Colorectal Neoplasms
Therapeutics
Guidelines
Standard of Care
2018

5-fluoropyrimidines

Ryan, D. P., Grem, J. L. & Chabner, B. A., Jan 1 2018, Cancer Chemotherapy, Immunotherapy and Biotherapy: Principles and Practice, Sixth Edition. Wolters Kluwer Health, p. 114-135 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

5-fluoropyrimidine
17 Citations (Scopus)

Anal Carcinoma, version 2.2018 clinical practice guidelines in Oncology

Benson, A. B., Venook, A. P., Al-Hawary, M. M., Cederquist, L., Chen, Y. J., Ciombor, K. K., Cohen, S., Cooper, H. S., Deming, D., Engstrom, P. F., Grem, J. L., Grothey, A., Hochster, H. S., Hoffe, S., Hunt, S., Kamel, A., Kirilcuk, N., Krishnamurthi, S., Messersmith, W. A., Meyerhardt, J. & 14 others, Mulcahy, M. F., Murphy, J. D., Nurkin, S., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Sofocleous, C. T., Stoffel, E. M., Stotsky-Himelfarb, E., Willett, C. G., Wuthrick, E., Gregory, K. M. & Freedman-Cass, D. A., Jul 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 7, p. 852-871 20 p.

Research output: Contribution to journalReview article

Practice Guidelines
Anus Neoplasms
Carcinoma
Radiation Oncology
Medical Oncology
71 Citations (Scopus)

NCCN Guidelines ® Insights Colon Cancer, Version 2.2018 Featured Updates to the NCCN Guidelines

Benson, A. B., Venook, A. P., Al-Hawary, M. M., Cederquist, L., Chen, Y. J., Ciombor, K. K., Cohen, S., Cooper, H. S., Deming, D., Engstrom, P. F., Garrido-Laguna, I., Grem, J. L., Grothey, A., Hochster, H. S., Hoffe, S., Hunt, S., Kamel, A., Kirilcuk, N., Krishnamurthi, S., Messersmith, W. A. & 16 others, Meyerhardt, J., Miller, E. D., Mulcahy, M. F., Murphy, J. D., Nurkin, S., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Sofocleous, C. T., Stoffel, E. M., Stotsky-Himelfarb, E., Willett, C. G., Wuthrick, E., Gregory, K. M. & Freedman-Cass, D. A., Apr 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 4, p. 359-369 11 p.

Research output: Contribution to journalComment/debate

Colonic Neoplasms
Guidelines
Colorectal Neoplasms
Therapeutics
Survival Rate
61 Citations (Scopus)

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschênes, A., Somerville, T. D. D., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., Lacomb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. C., Johnson, M., Arora, K. & 50 others, Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., DiMaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O’kane, G. M., Notta, F., Kim, E., Crawford, J. M., Devoe, C., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R., Knox, J., Krasnitz, A., Gallinger, S. & Tuveson, D. A., Sep 2018, In : Cancer Discovery. 8, 9, p. 1112-1129 18 p.

Research output: Contribution to journalArticle

Organoids
Pancreatic Neoplasms
Drug Therapy
Therapeutics
Precision Medicine

Phase 2 study of treatment selection based on tumor thymidylate synthase expression in previously untreated patients with metastatic colorectal cancer: A trial of the ECOG-ACRIN Cancer Research Group (E4203)

Meropol, N. J., Feng, Y., Grem, J. L., Mulcahy, M. F., Catalano, P. J., Kauh, J. S., Hall, M. J., Saltzman, J. N., George, T. J., Zangmeister, J., Chiorean, E. G., Cheema, P. S., O'Dwyer, P. J. & Benson, A. B., Feb 15 2018, In : Cancer. 124, 4, p. 688-697 10 p.

Research output: Contribution to journalArticle

oxaliplatin
irinotecan
Thymidylate Synthase
Colorectal Neoplasms
Research
37 Citations (Scopus)

Rectal cancer, version 2.2018 clinical practice guidelines in Oncology

Benson, A. B., Venook, A. P., Al-Hawary, M. M., Cederquist, L., Chen, Y. J., Ciombor, K. K., Cohen, S., Cooper, H. S., Deming, D., Engstrom, P. F., Grem, J. L., Grothey, A., Hochster, H. S., Hoffe, S., Hunt, S., Kamel, A., Kirilcuk, N., Krishnamurthi, S., Messersmith, W. A., Meyerhardt, J. & 15 others, Mulcahy, M. F., Murphy, J. D., Nurkin, S., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Sofocleous, C. T., Stoffel, E. M., Stotsky-Himelfarb, E., Willett, C. G., Wuthrick, E., Freedman-Cass, D. A., Gregory, K. M. & Gurski, L., Jul 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 7, p. 874-901 28 p.

Research output: Contribution to journalReview article

Rectal Neoplasms
Practice Guidelines
Guidelines
Disease Management
Patient Selection
2017
214 Citations (Scopus)

Colon cancer, version 1.2017: Clinical practice guidelines in oncology

Benson, A. B., Venook, A. P., Cederquist, L., Chan, E., Chen, Y. J., Cooper, H. S., Deming, D., Engstrom, P. F., Enzinger, P. C., Fichera, A., Grem, J. L., Grothey, A., Hochster, H. S., Hoffe, S., Hunt, S., Kamel, A., Kirilcuk, N., Krishnamurthi, S., Messersmith, W. A., Mulcahy, M. F. & 13 others, Murphy, J. D., Nurkin, S., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Sofocleous, C. T., Stoffel, E. M., Stotsky-Himelfarb, E., Willett, C. G., Wu, C. S., Gregory, K. M. & Freedman-Cass, D., Mar 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 3, p. 370-398 29 p.

Research output: Contribution to journalReview article

Open Access
Practice Guidelines
Colonic Neoplasms
Patient Preference
Microsatellite Repeats
Comorbidity
16 Citations (Scopus)

De Novo lipid synthesis facilitates gemcitabine resistance through endoplasmic reticulum stress in pancreatic cancer

Tadros, S., Shukla, S. K., King, R. J., Gunda, V., Vernucci, E., Abrego, J., Chaika, N. V., Yu, F., Lazenby, A. J., Berim, L., Grem, J. L., Sasson, A. R. & Singh, P., Oct 15 2017, In : Cancer Research. 77, 20, p. 5503-5517 15 p.

Research output: Contribution to journalArticle

gemcitabine
Endoplasmic Reticulum Stress
Pancreatic Neoplasms
Lipids
Fatty Acid Synthases
69 Citations (Scopus)

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

Roe, J. S., Hwang, C. I., Somerville, T. D. D., Milazzo, J. P., Lee, E. J., Da Silva, B., Maiorino, L., Tiriac, H., Young, C. M., Miyabayashi, K., Filippini, D., Creighton, B., Burkhart, R. A., Buscaglia, J. M., Kim, E. J., Grem, J. L., Lazenby, A. J., Grunkemeyer, J. A., Hollingsworth, M. A., Grandgenett, P. M. & 4 others, Egeblad, M., Park, Y., Tuveson, D. A. & Vakoc, C. R., Aug 24 2017, In : Cell. 170, 5, p. 875-888.e20

Research output: Contribution to journalArticle

Transcription
Pancreatic Neoplasms
Adenocarcinoma
Chemical activation
Neoplasm Metastasis
9 Citations (Scopus)

Erratum: MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer (Cancer Cell (2017) 32(1) (71–87.e7) (S1535610817302544) (10.1016/j.ccell.2017.06.004))

Shukla, S. K., Purohit, V., Mehla, K., Gunda, V., Chaika, N. V., Vernucci, E., King, R. J., Abrego, J., Goode, G. D., Dasgupta, A., Illies, A. L., Gebregiworgis, T., Dai, B., Augustine, J. J., Murthy, D., Attri, K. S., Mashadova, O., Grandgenett, P. M., Powers, R., Ly, Q. P. & 17 others, Lazenby, A. J., Grem, J. L., Yu, F., Matés, J. M., Asara, J. M., Kim, J. W., Hankins, J. H., Weekes, C., Hollingsworth, M. A., Serkova, N. J., Sasson, A. R., Fleming, J. B., Oliveto, J. M., Lyssiotis, C. A., Cantley, L. C., Berim, L. & Singh, P., Sep 11 2017, In : Cancer Cell. 32, 3, 1 p.

Research output: Contribution to journalComment/debate

gemcitabine
Pancreatic Neoplasms
Names
Glucose
Neoplasms
74 Citations (Scopus)

MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

Shukla, S. K., Purohit, V., Mehla, K., Gunda, V., Chaika, N. V., Vernucci, E., King, R. J., Abrego, J., Goode, G. D., Dasgupta, A., Illies, A. L., Gebregiworgis, T., Dai, B., Augustine, J. J., Murthy, D., Attri, K. S., Mashadova, O., Grandgenett, P. M., Powers, R., Ly, Q. P. & 17 others, Lazenby, A. J., Grem, J. L., Yu, F., Matés, J. M., Asara, J. M., Kim, J. W., Hankins, J. H., Weekes, C., Hollingsworth, M. A., Sarkova, N. J., Sasson, A. R., Fleming, J. B., Oliveto, J. M., Lyssiotis, C. A., Cantley, L. C., Berim, L. & Singh, P., Jul 10 2017, In : Cancer Cell. 32, 1, p. 71-87.e7

Research output: Contribution to journalArticle

gemcitabine
Hypoxia-Inducible Factor 1
Pancreatic Neoplasms
Glucose
Tumor Burden
6 Citations (Scopus)

Pharmacokinetics and Biodistribution of GDC-0449 Loaded Micelles in Normal and Liver Fibrotic Mice

Dutta, R., Kumar, V., Peng, Y., Evande, R. E., Grem, J. L. & Mahato, R. I., Mar 1 2017, In : Pharmaceutical Research. 34, 3, p. 564-578 15 p.

Research output: Contribution to journalArticle

HhAntag691
Pharmacokinetics
Micelles
Liver
Hepatic Stellate Cells
2016
7 Citations (Scopus)

Biochemistry and Clinical Activity of N-(Phosphonacety1)-L-aspartate: A Review

Grem, J. L., King, S. A., O'Dwyer, P. J. & Leyland-Jones, B., Jan 1 2016, In : Cancer Research. 48, 16, p. 4441-4454 14 p.

Research output: Contribution to journalReview article

NSC 224131
Biochemistry
Pharmacology
Antimetabolites
National Cancer Institute (U.S.)
18 Citations (Scopus)

Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility

Clausen, T. M., Pereira, M. A., Nakouzi, N. A., Oo, H. Z., Agerbæk, M., Lee, S., Ørum-Madsen, M. S., Kristensen, A. R., El-Naggar, A., Grandgenett, P. M., Grem, J. L., Hollingsworth, M. A., Holst, P. J., Theander, T., Sorensen, P. H., Daugaard, M. & Salanti, A., Dec 1 2016, In : Molecular Cancer Research. 14, 12, p. 1288-1299 12 p.

Research output: Contribution to journalArticle

Integrins
Cell Movement
Neoplasms
Proteoglycans
chondroitin sulfate glycosaminoglycan

Pharmacogenomics of neurodegenerative diseases: Roles in personalized medicines

Evande, R. E., Dutta, R., Tan, C., Grem, J. L. & Mahato, R. I., Jan 1 2016, Neuroimmune Pharmacology. Springer International Publishing, p. 959-970 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Precision Medicine
Pharmacogenetics
Neurodegenerative Diseases
Pharmaceutical Preparations
Genomics
2015
2 Citations (Scopus)

A multicenter, open-label, phase 1 study evaluating the safety and tolerability of pegaspargase in combination with gemcitabine in advanced metastatic solid tumors and lymphoma

Borad, M. J., Babiker, H. M., Anthony, S., Mita, M., Buchbinder, A., Keilani, T. & Grem, J. L., May 28 2015, In : Cancer Investigation. 33, 5, p. 172-179 8 p.

Research output: Contribution to journalArticle

gemcitabine
Lymphoma
Safety
Neoplasms
Asparaginase
1 Citation (Scopus)
Clinical Trials, Phase I
Fluorouracil
Neoplasms
Disease-Free Survival
Folic Acid Antagonists
8 Citations (Scopus)

Impact of CYP2C19 polymorphism on the pharmacokinetics of nelfinavir in patients with pancreatic cancer

Kattel, K., Evande, R., Tan, C., Mondal, G., Grem, J. L. & Mahato, R. I., Aug 1 2015, In : British Journal of Clinical Pharmacology. 80, 2, p. 267-275 9 p.

Research output: Contribution to journalArticle

Nelfinavir
Pancreatic Neoplasms
Pharmacokinetics
Area Under Curve
Genotype
120 Citations (Scopus)

Rectal cancer, version 2.2015: Featured updates to the NCCN guidelines

Benson, A. B., Venook, A. P., Bekaii-Saab, T., Chan, E., Chen, Y. J., Cooper, H. S., Engstrom, P. F., Enzinger, P. C., Fenton, M. J., Fuchs, C. S., Grem, J. L., Grothey, A., Hochster, H. S., Hunt, S., Kamel, A., Kirilcuk, N., Leong, L. A., Lin, E., Messersmith, W. A., Mulcahy, M. F. & 14 others, Murphy, J. D., Nurkin, S., Rohren, E., Ryan, D. P., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Sofocleous, C. T., Stoffel, E. M., Stotsky-Himelfarb, E., Willett, C. G., Gregory, K. M. & Freedman-Cass, D., Jun 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 6, p. 719-728 10 p.

Research output: Contribution to journalArticle

Open Access
Rectal Neoplasms
Guidelines
Primary Care Physicians
Publications
Survival Rate
2014
145 Citations (Scopus)

Colon cancer, version 3.2014

Benson, A. B., Venook, A. P., Bekaii-Saab, T., Chan, E., Chen, Y. J., Cooper, H. S., Engstrom, P. F., Enzinger, P. C., Fenton, M. J., Fuchs, C. S., Grem, J. L., Hunt, S., Kamel, A., Leong, L. A., Lin, E., Messersmith, W., Mulcahy, M. F., Murphy, J. D., Nurkin, S., Rohren, E. & 11 others, Ryan, D. P., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Sofocleous, C. T., Stoffel, E. M., Stotsky-Himelfarb, E., Willett, C. G., Gregory, K. M. & Freedman-Cass, D. A., Jul 1 2014, In : JNCCN Journal of the National Comprehensive Cancer Network. 12, 7, p. 1028-1059 32 p.

Research output: Contribution to journalArticle

Open Access
Colonic Neoplasms
Guidelines
Therapeutics
Continuity of Patient Care
Patient Preference
2 Citations (Scopus)

Erratum: NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors (Evidence-based Complementary and Alternative Medicine)

Mansky, P. J., Wallerstedt, D. B., Sannes, T. S., Stagl, J., Johnson, L. L., Blackman, M. R., Grem, J. L., Swain, S. M. & Monahan, B. P., 2014, In : Evidence-based Complementary and Alternative Medicine. 2014, 606348.

Research output: Contribution to journalComment/debate

gemcitabine
Mistletoe
Evidence-Based Medicine
Complementary Therapies
Neoplasms
2013
55 Citations (Scopus)

Localized Colon Cancer, version 3.2013

Benson, A. B., Bekaii-Saab, T., Chan, E., Chen, Y. J., Choti, M. A., Cooper, H. S., Engstrom, P. F., Enzinger, P. C., Fakih, M. G., Fenton, M. J., Fuchs, C. S., Grem, J. L., Hunt, S., Kamel, A., Leong, L. A., Lin, E., May, K. S., Mulcahy, M. F., Murphy, K., Rohren, E. & 11 others, Ryan, D. P., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Small, W., Sofocleous, C. T., Venook, A. P., Willett, C. G., Gregory, K. M. & Freedman-Cass, D. A., Jan 1 2013, In : JNCCN Journal of the National Comprehensive Cancer Network. 11, 5, p. 519-528 10 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Guidelines
Primary Care Physicians
Practice Guidelines
Survival Rate
111 Citations (Scopus)

Metastatic colon cancer, version 3.2013: Featured updates to the NCCN guidelines

Benson, A. B., Bekaii-Saab, T., Chan, E., Chen, Y. J., Choti, M. A., Cooper, H. S., Engstrom, P. F., Enzinger, P. C., Fakih, M. G., Fenton, M. J., Fuchs, C. S., Grem, J. L., Hunt, S., Kamel, A., Leong, L. A., Lin, E., May, K. S., Mulcahy, M. F., Murphy, K., Rohren, E. & 11 others, Ryan, D. P., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Jr, W. S., Sofocleous, C. T., Venook, A. P., Willett, C. G., Gregory, K. M. & Freedman-Cass, D. A., Feb 1 2013, In : JNCCN Journal of the National Comprehensive Cancer Network. 11, 2, p. 141-152 12 p.

Research output: Contribution to journalArticle

Open Access
Colonic Neoplasms
Guidelines
Continuity of Patient Care
Primary Care Physicians
Practice Guidelines
23 Citations (Scopus)

Nccam/nci phase 1 study of mistletoe extract and gemcitabine in patients with advanced solid tumors

Mansky, P. J., Wallerstedt, D. B., Sannes, T. S., Stagl, J., Johnson, L. L., Blackman, M. R., Grem, J. L., Swain, S. M. & Monahan, B. P., Dec 4 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 964592.

Research output: Contribution to journalArticle

gemcitabine
Mistletoe
Neoplasms
Maximum Tolerated Dose
Viscum album
3 Citations (Scopus)

Sequencing of treatment in advanced unresectable colorectal cancer

Grem, J. L., Sep 1 2013, In : JNCCN Journal of the National Comprehensive Cancer Network. 11, SUPPL.4, p. S28-S37

Research output: Contribution to journalArticle

Colorectal Neoplasms
Therapeutics
Disease Progression
Drug Therapy
Patient Preference
2012
57 Citations (Scopus)

Anal carcinoma, version 2.2012: Featured updates to the NCCN guidelines

Benson, A. B., Arnoletti, J. P., Bekaii-Saab, T., Chan, E., Chen, Y. J., Choti, M. A., Cooper, H. S., Dilawari, R. A., Engstrom, P. F., Enzinger, P. C., Fakih, M. G., Fleshman, J. W., Fuchs, C. S., Grem, J. L., Leong, L. A., Lin, E., May, K. S., Mulcahy, M. F., Murphy, K., Rohren, E. & 10 others, Ryan, D. P., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Small, W., Sofocleous, C. T., Venook, A. P., Willett, C. & Freedman-Cass, D. A., Apr 1 2012, In : JNCCN Journal of the National Comprehensive Cancer Network. 10, 4, p. 449-454 6 p.

Research output: Contribution to journalReview article

Open Access
Anus Neoplasms
Guidelines
Carcinoma
Radiotherapy
Anal Canal
108 Citations (Scopus)

Rectal cancer

Benson, A. B., Bekaii-Saab, T., Chan, E., Chen, Y. J., Choti, M. A., Cooper, H. S., Engstrom, P. F., Enzinger, P. C., Fakih, M. G., Fuchs, C. S., Grem, J. L., Hunt, S., Leong, L. A., Lin, E., Martin, M. G., May, K. S., Mulcahy, M. F., Murphy, K., Rohren, E., Ryan, D. P. & 10 others, Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Small, W., Sofocleous, C. T., Venook, A. P., Willett, C. G., Freedman-Cass, D. A. & Gregory, K. M., Dec 1 2012, In : JNCCN Journal of the National Comprehensive Cancer Network. 10, 12, p. 1528-1564 37 p.

Research output: Contribution to journalReview article

Rectal Neoplasms
Radiation Oncology
Neoadjuvant Therapy
Medical Oncology
Primary Care Physicians

Why we should not treat patients with stage II colon cancer

Subbiah, S. P. & Grem, J. L., Sep 1 2012, In : Current Colorectal Cancer Reports. 8, 3, p. 204-209 6 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Adjuvant Chemotherapy
Molecular Biology
Prospective Studies
Recurrence
2011
4 Citations (Scopus)

5-Fluoropyrimidines

Grem, J. L., Chabner, B. A., Ryan, D. P. & Wadlow, R. C., Dec 7 2011, Cancer Chemotherapy and Biotherapy: Principles and Practice. Wolters Kluwer Health Adis (ESP), p. 370-440 71 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

5-fluoropyrimidine
7 Citations (Scopus)

Brain metastasis and leptomeningeal carcinomatosis in a patient with cholangiocarcinoma

William, B. M. & Grem, J. L., Jul 1 2011, In : Gastrointestinal Cancer Research. 4, 4, p. 144-145 2 p.

Research output: Contribution to journalArticle

Meningeal Carcinomatosis
Cholangiocarcinoma
Neoplasm Metastasis
Brain
9 Citations (Scopus)

Clinical practice guidelines in oncology

Benson, A. B., Arnoletti, J. P., Bekaii-Saab, T., Chan, E., Chen, Y. J., Choti, M. A., Cooper, H. S., Dilawari, R. A., Engstrom, P. F., Enzinger, P. C., Fleshman, J. W., Fuchs, C. S., Grem, J. L., Knol, J. A., Leong, L. A., Lin, E., May, K. S., Mulcahy, M. F., Murphy, K., Rohren, E. & 9 others, Ryan, D. P., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Small, W., Sofocleous, C. T., Venook, A. P. & Willett, C., Nov 1 2011, In : JNCCN Journal of the National Comprehensive Cancer Network. 9, 11, p. 1238-1289 52 p.

Research output: Contribution to journalReview article

Practice Guidelines
oxaliplatin
Therapeutics
Drug Therapy
Fluorouracil
25 Citations (Scopus)

Colon cancer.

Benson, A. B., Arnoletti, J. P., Bekaii-Saab, T., Chan, E., Chen, Y. J., Choti, M. A., Cooper, H. S., Dilawari, R. A., Engstrom, P. F., Enzinger, P. C., Fleshman, J. W., Fuchs, C. S., Grem, J. L., Knol, J. A., Leong, L. A., Lin, E., May, K. S., Mulcahy, M. F., Murphy, K., Rohren, E. & 10 others, Ryan, D. P., Saltz, L., Sharma, S., Shibata, D., Skibber, J. M., Small, W., Sofocleous, C. T., Venook, A. P., Willett, C. & National Comprehensive Cancer Network, C. C. N., Nov 1 2011, In : Journal of the National Comprehensive Cancer Network : JNCCN. 9, 11, p. 1238-1290 53 p.

Research output: Contribution to journalArticle

Digestive System Surgical Procedures
Antineoplastic Combined Chemotherapy Protocols
Maintenance Chemotherapy
Combined Modality Therapy
Neoadjuvant Therapy
2010
39 Citations (Scopus)

Anal carcinoma: Clinical practice guidelines in oncology™

Engstrom, P. F., Arnoletti, J. P., Benson, A. B., Berlin, J. D., Berry, J. M., Chen, Y. J., Choti, M. A., Cooper, H. S., Dilawari, R. A., Early, D. S., Enzinger, P. C., Fakih, M. G., Fleshman, J., Fuchs, C., Grem, J. L., Knol, J. A., Leong, L. A., Lin, E., Mulcahy, M. F., Rohren, E. & 9 others, Ryan, D. P., Saltz, L., Shibata, D., Skibber, J. M., Small, W., Sofocleous, C., Thomas, J., Venook, A. P. & Willett, C., Jan 2010, In : JNCCN Journal of the National Comprehensive Cancer Network. 8, 1, p. 106-120 15 p.

Research output: Contribution to journalArticle

Open Access
Practice Guidelines
Groin
Carcinoma
Dissection
Clinical Trials
40 Citations (Scopus)

Fatigue and other variables during adjuvant chemotherapy for colon and rectal cancer.

Berger, A. M., Grem, J. L., Visovsky, C., Marunda, H. A. & Yurkovich, J. M., Nov 1 2010, In : Oncology nursing forum. 37, 6, p. E359-369

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Rectal Neoplasms
Colonic Neoplasms
Fatigue
Sleep
2009
236 Citations (Scopus)

Colon cancer

Engstrom, P. F., Arnoletti, J. P., Benson, A. B., Chen, Y. J., Choti, M. A., Cooper, H. S., Covey, A., Dilawari, R. A., Early, D. S., Enzinger, P. C., Fakih, M. G., Fleshman, J., Fuchs, C., Grem, J. L., Kiel, K., Knol, J. A., Leong, L. A., Lin, E., Mulcahy, M. F., Rao, S. & 8 others, Ryan, D. P., Saltz, L., Shibata, D., Skibber, J. M., Sofocleous, C., Thomas, J., Venook, A. P. & Willett, C., Sep 2009, In : JNCCN Journal of the National Comprehensive Cancer Network. 7, 8, p. 778-831 54 p.

Research output: Contribution to journalReview article

Open Access
Colonic Neoplasms
Therapeutics
Drug Therapy
Anus Neoplasms
Continuity of Patient Care
199 Citations (Scopus)

National Institutes of Health consensus development conference statement: Management of hepatitis B

Sorrell, M. F., Belongia, E. A., Costa, J., Gareen, I. F., Grem, J. L., Inadomi, J. M., Kern, E. R., McHugh, J. A., Petersen, G. M., Rein, M. F., Strader, D. B. & Trotter, H. T., Jan 20 2009, In : Annals of internal medicine. 150, 2, p. 104-110 7 p.

Research output: Contribution to journalArticle

Open Access
Consensus Development Conferences
National Institutes of Health (U.S.)
Hepatitis B
Health Services Research
Contracts
79 Citations (Scopus)

National Institutes of Health consensus development conference statement: Management of hepatitis B

Sorrell, M. F., Belongia, E. A., Costa, J., Gareen, I. F., Grem, J. L., Inadomi, J. M., Kern, E. R., McHugh, J. A., Petersen, G. M., Rein, M. F., Strader, D. B. & Trotter, H. T., May 1 2009, In : Hepatology. 49, SUPPL. 5, p. S4-S12

Research output: Contribution to journalArticle

Consensus Development Conferences
Chronic Hepatitis B
National Institutes of Health (U.S.)
Hepatitis B
Research
186 Citations (Scopus)

Rectal cancer

Engstrom, P. F., Arnoletti, J. P., Benson, A. B., Chen, Y. J., Choti, M. A., Cooper, H. S., Covey, A., Dilawari, R. A., Early, D. S., Enzinger, P. C., Fakih, M. G., Fleshman, J., Fuchs, C., Grem, J. L., Kiel, K., Knol, J. A., Leong, L. A., Lin, E., Mulcahy, M. F., Rao, S. & 8 others, Ryan, D. P., Saltz, L., Shibata, D., Skibber, J. M., Sofocleous, C., Thomas, J., Venook, A. P. & Willett, C., Sep 2009, In : JNCCN Journal of the National Comprehensive Cancer Network. 7, 8, p. 838-881 44 p.

Research output: Contribution to journalReview article

Open Access
Rectal Neoplasms
Therapeutics
Drug Therapy
Proctoscopy
Radiation Oncology
2008
54 Citations (Scopus)

NIH consensus development statement on management of hepatitis B

Belongia, E. A., Costa, J., Gareen, I. F., Grem, J. L., Inadomi, J. M., Kern, E. R., McHugh, J. A., Petersen, G. M., Rein, M. F., Sorrell, M. F., Strader, D. B. & Trotter, H. T., Jan 1 2008, In : NIH consensus and state-of-the-science statements. 25, 2, p. 1-29 29 p.

Research output: Contribution to journalArticle

Hepatitis B
Consensus
Fibrosis
Hepatocellular Carcinoma
DNA
68 Citations (Scopus)

Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of liver dysfunction: A study by the national cancer institute organ dysfunction working group

Ramanathan, R. K., Egorin, M. J., Takimoto, C. H. M., Remick, S. C., Doroshow, J. H., LoRusso, P. A., Mulkerin, D. L., Grem, J. L., Hamilton, A., Murgo, A. J., Potter, D. M., Belani, C. P., Hayes, M. J., Peng, B. & Ivy, S. P., Feb 1 2008, In : Journal of Clinical Oncology. 26, 4, p. 563-569 7 p.

Research output: Contribution to journalArticle

National Cancer Institute (U.S.)
Liver Diseases
Pharmacokinetics
Neoplasms
Nausea
73 Citations (Scopus)

Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: A study by the national cancer institute organ dysfunction working group

Gibbons, J., Egorin, M. J., Ramanathan, R. K., Fu, P., Mulkerin, D. L., Shibata, S., Takimoto, C. H. M., Mani, S., LoRusso, P. A., Grem, J. L., Pavlick, A., Lenz, H. J., Flick, S. M., Reynolds, S., Lagattuta, T. F., Parise, R. A., Wang, Y., Murgo, A. J., Ivy, S. P. & Remick, S. C., Feb 1 2008, In : Journal of Clinical Oncology. 26, 4, p. 570-576 7 p.

Research output: Contribution to journalArticle

National Cancer Institute (U.S.)
Pharmacokinetics
Kidney
Neoplasms
Creatinine
43 Citations (Scopus)
oxaliplatin
Dihydrouracil Dehydrogenase (NADP)
Thymidine Phosphorylase
Thymidylate Synthase
Adenocarcinoma
2007
9 Citations (Scopus)

Colon cancer

Engstrom, P. F., Arnoletti, J. P., Benson, A. B., Chen, Y. J., Choti, M. A., Cooper, H. S., Dilawari, R. A., Early, D. S., Fakih, M. G., Fuchs, C., Grem, J. L., Kiel, K., Knol, J. A., Leong, L. A., Ludwig, K. A., Martin, E. W., Rao, S., Saltz, L., Shibata, D., Skibber, J. M. & 1 others, Venook, A. P., Oct 1 2007, In : JNCCN Journal of the National Comprehensive Cancer Network. 5, 9, p. 884-925 42 p.

Research output: Contribution to journalReview article

Colonic Neoplasms
irinotecan
Fluorouracil
Therapeutics
Drug Therapy

Monoclonal antibodies in colorectal cancer: What we know

Grem, J. L., Jul 1 2007, In : ONCOLOGY. 21, 8, p. 970+974

Research output: Contribution to journalComment/debate

Colorectal Neoplasms
Monoclonal Antibodies
50 Citations (Scopus)

Oxaliplatin pharmacokinetics and pharmacodynamics in adult cancer patients with impaired renal function

Takimoto, C. H., Graham, M. A., Lockwood, G., Ng, C. M., Goetz, A., Greenslade, D., Remick, S. C., Sharma, S., Mani, S., Ramanathan, R. K., Synold, T. W., Doroshow, J. H., Hamilton, A., Mulkerin, D. L., Ivy, P., Egorin, M. J. & Grem, J. L., Aug 15 2007, In : Clinical Cancer Research. 13, 16, p. 4832-4839 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Creatinine
Pharmacokinetics
Kidney
Neoplasms
8 Citations (Scopus)

Rectal cancer

Engstrom, P. F., Arnoletti, J. P., Benson, A. B., Chen, Y. J., Choti, M. A., Cooper, H. S., Dilawari, R. A., Early, D. S., Fakih, M. G., Fuchs, C., Grem, J. L., Kiel, K., Knol, J. A., Leong, L. A., Ludwig, K. A., Martin, E. W., Rao, S., Saltz, L., Shibata, D., Skibber, J. M. & 1 others, Venook, A. P., Oct 1 2007, In : JNCCN Journal of the National Comprehensive Cancer Network. 5, 9, p. 940-981 42 p.

Research output: Contribution to journalReview article

Rectal Neoplasms
irinotecan
Therapeutics
Drug Therapy
Fluorouracil
2006

The patel/goldberg article reviewed

Grem, J. L., Dec 1 2006, In : ONCOLOGY. 20, 11, p. 1392-1393 2 p.

Research output: Contribution to journalComment/debate