• 7220 Citations
  • 38 h-Index
20022019
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Research Output 2002 2019

2019
1 Citation (Scopus)

Cancer-Associated Fibroblasts Enhance Survival and Progression of the Aggressive Pancreatic Tumor Via FGF-2 and CXCL8

Awaji, M., Futakuchi, M., Heavican, T., Iqbal, J. & Singh, R. K., Apr 1 2019, In : Cancer Microenvironment. 12, 1, p. 37-46 10 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Survival
Neoplasms
Coculture Techniques
Conditioned Culture Medium
5 Citations (Scopus)

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

Heavican, T. B., Bouska, A., Yu, J., Lone, W., Amador, C., Gong, Q., Zhang, W., Li, Y., Dave, B. J., Nairismägi, M. L., Greiner, T. C., Vose, J., Weisenburger, D. D., Lachel, C., Wang, C., Fu, K., Stevens, J. M., Lim, S. T., Ong, C. K., Gascoyne, R. D. & 27 others, Missiaglia, E., Lemonnier, F., Haioun, C., Hartmann, S., Pedersen, M. B., Laginestra, M. A., Wilcox, R. A., Teh, B. T., Yoshida, N., Ohshima, K., Seto, M., Rosenwald, A., Ott, G., Campo, E., Rimsza, L. M., Jaffe, E. S., Braziel, R. M., d’Amore, F., Inghirami, G., Bertoni, F., de Leval, L., Gaulard, P., Staudt, L. M., McKeithan, T. W., Pileri, S., Chan, W. C. & Iqbal, J., Apr 11 2019, In : Blood. 133, 15, p. 1664-1676 13 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
T-cells
T-Cell Lymphoma
Mutation
Genes

Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma

Maura, F., Agnelli, L., Leongamornlert, D., Bolli, N., Chan, W. C., Dodero, A., Carniti, C., Heavican, T. B., Pellegrinelli, A., Pruneri, G., Butler, A., Bhosle, S. G., Chiappella, A., Di Rocco, A., Zinzani, P. L., Zaja, F., Piva, R., Inghirami, G., Wang, W., Palomero, T. & 4 others, Iqbal, J., Neri, A., Campbell, P. J. & Corradini, P., Jun 2019, In : American Journal of Hematology. 94, 6, p. 628-634 7 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Lymphoma
Genes
RNA Sequence Analysis
Anaplastic Large-Cell Lymphoma
2 Citations (Scopus)

L-type cav 1.2 calcium channel-a-1C regulates response to rituximab in diffuse large B-cell lymphoma

Zhang, J. Y., Zhang, P. P., Zhou, W. P., Yu, J. Y., Yao, Z. H., Chu, J. F., Yao, S. N., Wang, C., Lone, W., Xia, Q. X., Ma, J., Yang, S. J., Liu, K. D., Dong, Z. G., Guo, Y. J., Smith, L. M., McKeithan, T. W., Chan, W. C., Iqbal, J. & Liu, Y. Y., Jan 1 2019, In : Clinical Cancer Research. 25, 13, p. 4168-4178 11 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Calcium Channels
Vincristine
Prednisone
Doxorubicin
1 Citation (Scopus)

Molecular and Genomic Landscape of Peripheral T-Cell Lymphoma

Iqbal, J., Amador, C., McKeithan, T. W. & Chan, W. C., Jan 1 2019, In : Cancer Treatment and Research. 176, p. 31-68 38 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
T-Cell Lymphoma
Gene Expression Profiling
Mutation
Sezary Syndrome
2 Citations (Scopus)

Phase I/II study of dasatinib and exploratory genomic analysis in relapsed or refractory non-Hodgkin lymphoma

Umakanthan, J. M., Iqbal, J., Batlevi, C. L., Bouska, A., Smith, L. M., Shostrom, V., Nutsch, H., William, B. M., Bociek, R. G., Lunning, M. A., Bierman, P. J., Younes, A., Armitage, J. O. & Vose, J. M., Mar 2019, In : British Journal of Haematology. 184, 5, p. 744-752 9 p.

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Follicular Lymphoma
Peripheral T-Cell Lymphoma
Mutation
Lymphoma, Large B-Cell, Diffuse

The miR-17~92 cluster activates mTORC1 in mantle cell lymphoma by targeting multiple regulators in the STK11/AMPK/TSC/mTOR pathway

Jiang, C., Bi, C., Jiang, X., Tian, T., Huang, X., Wang, C., Fernandez, M. R., Iqbal, J., Chan, W. C., McKeithan, T. W., Lewis, R. E. & Fu, K., May 2019, In : British Journal of Haematology. 185, 3, p. 616-620 5 p.

Research output: Contribution to journalLetter

Mantle-Cell Lymphoma
AMP-Activated Protein Kinases
mechanistic target of rapamycin complex 1

Transcriptional Analysis of Lennert Lymphoma Reveals a Unique Profile and Identifies Novel Therapeutic Targets

Etebari, M., Navari, M., Agostinelli, C., Visani, A., Peron, C., Iqbal, J., Inghirami, G. & Piccaluga, P. P., Sep 10 2019, In : Frontiers in Genetics. 10, 780.

Research output: Contribution to journalArticle

Open Access
Lymphoma
Peripheral T-Cell Lymphoma
MicroRNAs
T-Lymphocytes
Phosphatidylinositol 3-Kinases
2018

Caveolin-1 is dispensable for early lymphoid development, but plays a role in the maintenance of the mature splenic microenvironment

Herek, T. A., Robinson, J. E., Heavican, T. B., Amador, C., Iqbal, J. & Cutucache, C. E., Jul 13 2018, In : BMC Research Notes. 11, 1, 470.

Research output: Contribution to journalArticle

Caveolin 1
Cells
Maintenance
B-Lymphocytes
Splenomegaly
4 Citations (Scopus)

Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS

Sugio, T., Miyawaki, K., Kato, K., Sasaki, K., Yamada, K., Iqbal, J., Miyamoto, T., Ohshima, K., Maeda, T., Miyoshi, H. & Akashi, K., Sep 11 2018, In : Blood Advances. 2, 17, p. 2242-2252 11 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Neoplasms
Macrophages
Transcriptome
Dendritic Cells
3 Citations (Scopus)

Molecular Insights Into Pathogenesis of Peripheral T Cell Lymphoma: a Review

Lone, W., Alkhiniji, A., Manikkam Umakanthan, J. & Iqbal, J., Aug 1 2018, In : Current Hematologic Malignancy Reports. 13, 4, p. 318-328 11 p.

Research output: Contribution to journalReview article

Peripheral T-Cell Lymphoma
Gene Expression Profiling
Epigenomics
T-Lymphocytes
Mutation
2017
14 Citations (Scopus)

Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: Genomic features and potential therapeutic targets

Bouska, A., Bi, C., Lone, W., Zhang, W., Kedwaii, A., Heavican, T., Lachel, C. M., Yu, J., Ferro, R., Eldorghamy, N., Greiner, T. C., Vose, J. M., Weisenburger, D. D., Gascoyne, R. D., Rosenwald, A., Ott, G., Campo, E., Rimsza, L. M., Jaffe, E. S., Braziel, R. M. & 12 others, Siebert, R., Miles, R. R., Dave, S., Reddy, A., Delabie, J., Staudt, L. M., Song, J. Y., McKeithan, T. W., Fu, K., Green, M., Chan, W. C. & Iqbal, J., Oct 19 2017, In : Blood. 130, 16, p. 1819-1831 13 p.

Research output: Contribution to journalArticle

Burkitt Lymphoma
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Genes
Cells
11 Citations (Scopus)

Assessment of T-cell receptor repertoire and clonal expansion in peripheral T-cell lymphoma using RNA-seq data

Gong, Q., Wang, C., Zhang, W., Iqbal, J., Hu, Y., Greiner, T. C., Cornish, A., Kim, J. H., Rabadan, R., Abate, F., Wang, X., Inghirami, G. G., McKeithan, T. W. & Chan, W. C., Dec 1 2017, In : Scientific reports. 7, 1, 11301.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
T-Cell Antigen Receptor
RNA
T-Lymphocytes
Complementarity Determining Regions
9 Citations (Scopus)

ChimeRScope: A novel alignment-free algorithm for fusion transcript prediction using paired-end RNA-Seq data

Li, Y., Heavican, T. B., Vellichirammal, N. N., Iqbal, J. & Guda, C., Jul 1 2017, In : Nucleic acids research. 45, 13, e120.

Research output: Contribution to journalArticle

RNA
Galaxies
Software
Neoplasms
Sequence Alignment
27 Citations (Scopus)

Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma

Bouska, A., Zhang, W., Gong, Q., Iqbal, J., Scuto, A., Vose, J. M., Ludvigsen, M., Fu, K., Weisenburger, D. D., Greiner, T. C., Gascoyne, R. D., Rosenwald, A., Ott, G., Campo, E., Rimsza, L. M., Delabie, J., Jaffe, E. S., Braziel, R. M., Connors, J. M., Wu, C. I. & 4 others, Staudt, L. M., D‘Amore, F., McKeithan, T. W. & Chan, W. C., Jan 1 2017, In : Leukemia. 31, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Mutation
Genes
Lymphoma
Clonal Evolution
34 Citations (Scopus)

Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2

Moffitt, A. B., Ondrejka, S. L., McKinney, M., Rempel, R. E., Goodlad, J. R., Teh, C. H., Leppa, S., Mannisto, S., Kovanen, P. E., Tse, E., Au-Yeung, R. K. H., Kwong, Y. L., Srivastava, G., Iqbal, J., Yu, J., Naresh, K., Villa, D., Gascoyne, R. D., Said, J., Czader, M. B. & 16 others, Chadburn, A., Richards, K. L., Rajagopalan, D., Davis, N. S., Smith, E. C., Palus, B. C., Tzeng, T. J., Healy, J. A., Lugar, P. L., Datta, J., Love, C., Levy, S., Dunson, D. B., Zhuang, Y., Hsi, E. D. & Dave, S. S., May 1 2017, In : Journal of Experimental Medicine. 214, 5, p. 1371-1386 16 p.

Research output: Contribution to journalArticle

Enteropathy-Associated T-Cell Lymphoma
T-Lymphocytes
Exome
Mutation
T-Cell Lymphoma
144 Citations (Scopus)

Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma

Reddy, A., Zhang, J., Davis, N. S., Moffitt, A. B., Love, C. L., Waldrop, A., Leppa, S., Pasanen, A., Meriranta, L., Karjalainen-Lindsberg, M. L., Nørgaard, P., Pedersen, M., Gang, A. O., Høgdall, E., Heavican, T. B., Lone, W., Iqbal, J., Qin, Q., Li, G., Kim, S. Y. & 39 others, Healy, J., Richards, K. L., Fedoriw, Y., Bernal-Mizrachi, L., Koff, J. L., Staton, A. D., Flowers, C. R., Paltiel, O., Goldschmidt, N., Calaminici, M., Clear, A., Gribben, J., Nguyen, E., Czader, M. B., Ondrejka, S. L., Collie, A., Hsi, E. D., Tse, E., Au-Yeung, R. K. H., Kwong, Y. L., Srivastava, G., Choi, W. W. L., Evens, A. M., Pilichowska, M., Sengar, M., Reddy, N., Li, S., Chadburn, A., Gordon, L. I., Jaffe, E. S., Levy, S., Rempel, R., Tzeng, T., Happ, L. E., Dave, T., Rajagopalan, D., Datta, J., Dunson, D. B. & Dave, S. S., Oct 5 2017, In : Cell. 171, 2, p. 481-494.e15

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Clustered Regularly Interspaced Short Palindromic Repeats
Cells
Inborn Genetic Diseases
Cell growth
50 Citations (Scopus)

The genetic basis of hepatosplenic T-cell lymphoma

McKinney, M., Moffitt, A. B., Gaulard, P., Travert, M., Leval, L. D., Raffeld, A. N. M., Jaffe, E. S., Pittaluga, S., Xi, L., Heavican, T., Iqbal, J., Belhadj, K., Delfau-Larue, M. H., Fataccioli, V., Czader, M. B., Lossos, I. S., Chapman-Fredricks, J. R., Richards, K. L., Fedoriw, Y., Ondrejka, S. L. & 35 others, Hsi, E. D., Low, L., Weisenburger, D., Chan, W. C., Mehta-Shah, N., Horwitz, S., Bernal-Mizrachi, L., Flowers, C. R., Beaven, A. W., Parihar, M., Baseggio, L., Parrens, M., Moreau, A., Sujobert, P., Pilichowska, M., Evens, A. M., Chadburn, A., Au-Yeung, R. K. H., Srivastava, G., Choi, W. W. L., Goodlad, J. R., Aurer, I., Basic-Kinda, S., Gascoyne, R. D., Davis, N. S., Li, G., Zhang, J., Rajagopalan, D., Reddy, A., Love, C., Levy, S., Zhuang, Y., Datta, J., Dunson, D. B. & Davé, S. S., Apr 2017, In : Cancer Discovery. 7, 4, p. 369-379 11 p.

Research output: Contribution to journalArticle

T-Cell Lymphoma
Exome
Tumor Suppressor Genes
Mutation
Genes
2016
8 Citations (Scopus)

CD1d-restricted peripheral T cell lymphoma in mice and humans

Bachy, E., Urb, M., Chandra, S., Robinot, R., Bricard, G., de Bernard, S., Traverse-Glehen, A., Gazzo, S., Blond, O., Khurana, A., Baseggio, L., Heavican, T., Ffrench, M., Crispatzu, G., Mondière, P., Schrader, A., Taillardet, M., Thaunat, O., Martin, N., Dalle, S. & 15 others, Le Garff-Tavernier, M., Salles, G., Lachuer, J., Hermine, O., Asnafi, V., Roussel, M., Lamy, T., Herling, M., Iqbal, J., Buffat, L., Marche, P. N., Gaulard, P., Kronenberg, M., Defrance, T. & Genestier, L., Jan 1 2016, In : Journal of Experimental Medicine. 213, 5, p. 841-857 17 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Natural Killer T-Cells
Lymphoma
Blocking Antibodies
T-Lymphocytes
14 Citations (Scopus)

Genomic signatures in B-cell lymphoma: How can these improve precision in diagnosis and inform prognosis?

Iqbal, J., Naushad Qureishi, H., Bi, C., Yu, J., Bouska, A., Rohr, J., Chao, W., Fu, K., Chan, W. C. & Vose, J. M., Mar 1 2016, In : Blood Reviews. 30, 2, p. 73-88 16 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Mantle-Cell Lymphoma
Burkitt Lymphoma
Lymphoma, Large B-Cell, Diffuse
Phase III Clinical Trials
25 Citations (Scopus)

Genomic signatures in T-cell lymphoma: How can these improve precision in diagnosis and inform prognosis?

Iqbal, J., Wilcox, R., Naushad Qureishi, H., Rohr, J., Heavican, T. B., Wang, C., Bouska, A., Fu, K., Chan, W. C. & Vose, J. M., Mar 1 2016, In : Blood Reviews. 30, 2, p. 89-100 12 p.

Research output: Contribution to journalArticle

T-Cell Lymphoma
Peripheral T-Cell Lymphoma
Genome
Natural Killer Cells
Immunophenotyping
6 Citations (Scopus)

Loss of Dnmt3a induces CLL and PTCL with distinct methylomes and transcriptomes in mice

Haney, S. L., Upchurch, G. M., Opavska, J., Klinkebiel, D. L., Appiah, A. K., Smith, L. M., Heavican, T. B., Iqbal, J., Joshi, S. S. & Opavsky, R., Sep 28 2016, In : Scientific reports. 6, 34222.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
B-Cell Chronic Lymphocytic Leukemia
Transcriptome
Methylation
T-Lymphocytes
38 Citations (Scopus)

Recurrent activating mutations of CD28 in peripheral T-cell lymphomas

Rohr, J., Guo, S., Huo, J., Bouska, A., Lachel, C., Li, Y., Simone, P. D., Zhang, W., Gong, Q., Wang, C., Cannon, A., Heavican, T., Mottok, A., Hung, S., Rosenwald, A., Gascoyne, R., Fu, K., Greiner, T. C., Weisenburger, D. D., Vose, J. M. & 8 others, Staudt, L. M., Xiao, W., Borgstahl, G. E., Davis, S., Steidl, C., McKeithan, T., Iqbal, J. & Chan, W. C., May 1 2016, In : Leukemia. 30, 5, p. 1062-1070 9 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
Mutation
T-Cell Lymphoma
T-Cell Antigen Receptor
GRB2 Adaptor Protein

Role of c-MYC/miRNA-548/HDAC6 axis in drug resistance and lymphoma survival

Lone, W. G., Yu, J. & Iqbal, J., Jan 1 2016, In : Translational Cancer Research. 5, p. S146-S148

Research output: Contribution to journalComment/debate

MicroRNAs
Drug Resistance
Lymphoma
2015
166 Citations (Scopus)

Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

Küçük, C., Jiang, B., Hu, X., Zhang, W., Chan, J. K. C., Xiao, W., Lack, N., Alkan, C., Williams, J. C., Avery, K. N., Kavak, P., Scuto, A., Sen, E., Gaulard, P., Staudt, L., Iqbal, J., Zhang, W., Cornish, A., Gong, Q., Yang, Q. & 8 others, Sun, H., D'Amore, F., Leppä, S., Liu, W., Fu, K., De Leval, L., McKeithan, T. & Chan, W. C., Jan 2015, In : Nature communications. 6, 6025.

Research output: Contribution to journalArticle

T-cells
T-Cell Lymphoma
mutations
Natural Killer Cells
Lymphoma
19 Citations (Scopus)

A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation

Abate, F., Todaro, M., Van Der Krogt, J. A., Boi, M., Landra, I., Machiorlatti, R., Tabbò, F., Messana, K., Abele, C., Barreca, A., Novero, D., Gaudiano, M., Aliberti, S., Di Giacomo, F., Tousseyn, T., Lasorsa, E., Crescenzo, R., Bessone, L., Ficarra, E., Acquaviva, A. & 21 others, Rinaldi, A., Ponzoni, M., Longo, D. L., Aime, S., Cheng, M., Ruggeri, B., Piccaluga, P. P., Pileri, S., Tiacci, E., Falini, B., Pera-Gresely, B., Cerchietti, L., Iqbal, J., Chan, W. C., Shultz, L. D., Kwee, I., Piva, R., Wlodarska, I., Rabadan, R., Bertoni, F. & Inghirami, G., Jun 9 2015, In : Leukemia. 29, 6, p. 1390-1401 12 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 1
Anaplastic Large-Cell Lymphoma
Lymphoma
Proteasome Inhibitors
anaplastic lymphoma kinase
157 Citations (Scopus)

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma

The European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium Genetics-Driven Targeted Management of Lymphoid Malignancies, Apr 13 2015, In : Cancer Cell. 27, 4, p. 516-532 17 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Gene Fusion
Point Mutation
Protein-Tyrosine Kinases
Transcription Factors
2 Citations (Scopus)
59 Citations (Scopus)

Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphoma

Iqbal, J., Shen, Y., Huang, X., Liu, Y., Wake, L., Liu, C., Deffenbacher, K., Lachel, C. M., Wang, C., Rohr, J., Guo, S., Smith, L. M., Wright, G., Bhagavathi, S., Dybkaer, K., Fu, K., Greiner, T. C., Vose, J. M., Jaffe, E., Rimsza, L. & 13 others, Rosenwald, A., Ott, G., Delabie, J., Campo, E., Braziel, R. M., Cook, J. R., Tubbs, R. R., Armitage, J. O., Weisenburger, D. D., Staudt, L. M., Gascoyne, R. D., McKeithan, T. W. & Chan, W. C., Feb 12 2015, In : Blood. 125, 7, p. 1137-1145 9 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
MicroRNAs
Cells
B-Lymphocytes
B-Lymphocyte Subsets
32 Citations (Scopus)

Global promoter methylation analysis reveals novel candidate tumor suppressor genes in natural killer cell lymphoma

Küçük, C., Hu, X., Jiang, B., Klinkebiel, D. L., Geng, H., Gong, Q., Bouska, A., Iqbal, J., Gaulard, P., McKeithan, T. W. & Chan, W. C., Apr 1 2015, In : Clinical Cancer Research. 21, 7, p. 1699-1711 13 p.

Research output: Contribution to journalArticle

Tumor Suppressor Genes
Natural Killer Cells
Methylation
Lymphoma
Cell Line
34 Citations (Scopus)

High-resolution chromatin immunoprecipitation (ChIP) sequencing reveals novel binding targets and prognostic role for SOX11 in mantle cell lymphoma

Kuo, P. Y., Leshchenko, V. V., Fazzari, M. J., Perumal, D., Gellen, T., He, T., Iqbal, J., Baumgartner-Wennerholm, S., Nygren, L., Zhang, F., Zhang, W., Suh, K. S., Goy, A., Yang, D. T., Chan, W. C., Kahl, B. S., Verma, A. K., Gascoyne, R. D., Kimby, E., Sander, B. & 3 others, Ye, B. H., Melnick, A. M. & Parekh, S., Mar 5 2015, In : Oncogene. 34, 10, p. 1231-1240 10 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Chromatin Immunoprecipitation
Genes
British Columbia
RNA Interference
71 Citations (Scopus)

IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma

Wang, C., McKeithan, T. W., Gong, Q., Zhang, W., Bouska, A., Rosenwald, A., Gascoyne, R. D., Wu, X., Wang, J., Zahid, M., Jiang, B., Rohr, J., Cannon, A., Steidl, C., Fu, K., Li, Y., Hung, S., Weisenburger, D. D., Greiner, T. C., Smith, L. M. & 6 others, Ott, G., Rogan, E. G., Staudt, L. M., Vose, J. M., Iqbal, J. & Chan, W. C., Oct 8 2015, In : Blood. 126, 15, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

T-cells
T-Cell Lymphoma
Mutation
Peripheral T-Cell Lymphoma
Isocitrate Dehydrogenase
2014
38 Citations (Scopus)

Chronic lymphocytic leukemia cells in a lymph node microenvironment depict molecular signature associated with an aggressive disease

Mittal, A. K., Chaturvedi, N. K., Rai, K. J., Cutucache, C. E., Nordgren, T. M., Moragues, M., Lu, R., Opavsky, R., Bociek, R. G., Weisenburger, D. D., Iqbal, J. & Joshi, S. S., Jan 1 2014, In : Molecular Medicine. 20, 1, p. 290-301 12 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Lymph Nodes
B-Lymphocytes
Gene Expression Profiling
Cytoplasmic and Nuclear Receptors
29 Citations (Scopus)

EZH2 mutations in follicular lymphoma from different ethnic groups and associated gene expression alterations

Guo, S., Chan, J. K. C., Iqbal, J., McKeithan, T., Fu, K., Meng, B., Pan, Y., Cheuk, W., Luo, D., Wang, R., Zhang, W., Greiner, T. C. & Chan, W. C., Jun 15 2014, In : Clinical Cancer Research. 20, 12, p. 3078-3086 9 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Ethnic Groups
Gene Expression
Mutation
Gene Expression Profiling
172 Citations (Scopus)

Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

Iqbal, J., Wright, G., Wang, C., Rosenwald, A., Gascoyne, R. D., Weisenburger, D. D., Greiner, T. C., Smith, L. M., Guo, S., Wilcox, R. A., Teh, B. T., Lim, S. T., Tan, S. Y., Rimsza, L. M., Jaffe, E. S., Campo, E., Martinez, A., Delabie, J., Braziel, R. M., Cook, J. R. & 16 others, Tubbs, R. R., Ott, G., Geissinger, E., Gaulard, P., Piccaluga, P. P., Pileri, S. A., Au, W. Y., Nakamura, S., Seto, M., Berger, F., De Leval, L., Connors, J. M., Armitage, J. O., Vose, J. M., Chan, W. C. & Staudt, L. M., May 8 2014, In : Blood. 123, 19, p. 2915-2923 9 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
T-cells
Transcriptome
Gene expression
Extranodal NK-T-Cell Lymphoma
59 Citations (Scopus)

Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma

Bouska, A., McKeithan, T. W., Deffenbacher, K. E., Lachel, C., Wright, G. W., Iqbal, J., Smith, L. M., Zhang, W., Kucuk, C., Rinaldi, A., Bertoni, F., Fitzgibbon, J., Fu, K., Weisenburger, D. D., Greiner, T. C., Dave, B. J., Gascoyne, R. D., Rosenwald, A., Ott, G., Campo, E. & 7 others, Rimsza, L. M., Delabie, J., Jaffe, E. S., Braziel, R. M., Connors, J. M., Staudt, L. M. & Chan, W. C., Mar 13 2014, In : Blood. 123, 11, p. 1681-1690 10 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Genes
Genome
Chromosome Aberrations
Cells
6 Citations (Scopus)

Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells

Basma, H. E., Gunji, Y., Iwasawa, S., Nelson, A., Farid, M., Ikari, J., Liu, X., Wang, X., Michalski, J., Smith, L. M., Iqbal, J., El Behery, R., West, W., Yelamanchili, S. V., Rennard, D., Holz, O., Mueller, K. C., Magnussen, H., Rabe, K., Castaldi, P. J. & 1 others, Rennard, S. I., Mar 15 2014, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 306, 6, p. L552-L565

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Obstructive Lung Diseases
Chronic Obstructive Pulmonary Disease
Fibroblasts
Lung
33 Citations (Scopus)

STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma

Spaccarotella, E., Pellegrino, E., Ferracin, M., Ferreri, C., Cuccuru, G., Liu, C., Iqbal, J., Cantarella, D., Taulli, R., Provero, P., Cunto, F. D., Medico, E., Negrini, M., Chan, W. C., Inghirami, G. & Piva, R., Jan 1 2014, In : Haematologica. 99, 1, p. 116-124 9 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
MicroRNAs
Gene Rearrangement
T-Cell Lymphoma
Heterografts
45 Citations (Scopus)

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma

Green, M. R., Vicente-Dueñas, C., Romero-Camarero, I., Long Liu, C., Dai, B., González-Herrero, I., García-Ramírez, I., Alonso-Escudero, E., Iqbal, J., Chan, W. C., Campos-Sanchez, E., Orfao, A., Pintado, B., Flores, T., Blanco, O., Jiménez, R., Martínez-Climent, J. A., Criado, F. J. G., Cenador, M. B. G., Zhao, S. & 7 others, Natkunam, Y., Lossos, I. S., Majeti, R., Melnick, A., Cobaleda, C., Alizadeh, A. A. & Sánchez-García, I., Jun 2 2014, In : Nature communications. 5, 3904.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Hematopoietic Stem Cells
induction
Cells
stem cells
2013
76 Citations (Scopus)

Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP

Huang, X., Meng, B., Iqbal, J., Ding, B. B., Perry, A. M., Cao, W., Smith, L. M., Bi, C., Jiang, C., Greiner, T. C., Weisenburger, D. D., Rimsza, L., Rosenwald, A., Ott, G., Delabie, J., Campo, E., Braziel, R. M., Gascoyne, R. D., Cook, J. R., Tubbs, R. R. & 8 others, Jaffe, E. S., Armitage, J. O., Vose, J. M., Staudt, L. M., McKeithan, T. W., Chan, W. C., Ye, B. H. & Fu, K., Dec 30 2013, In : Journal of Clinical Oncology. 31, 36, p. 4520-4528 9 p.

Research output: Contribution to journalArticle

Phosphotyrosine
Lymphoma, Large B-Cell, Diffuse
B-Lymphocytes
Survival
Messenger RNA
9 Citations (Scopus)

CD43 expression is associated with inferior survival in the non-germinal centre B-cell subgroup of diffuse large B-cell lymphoma

Mitrovic, Z., Iqbal, J., Fu, K., Smith, L. M., Bast, M., Greiner, T. C., Aoun, P., Armitage, J. O., Vose, J. M., Weisenburger, D. D. & Chan, W. C., Jul 1 2013, In : British Journal of Haematology. 162, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
B-Lymphocytes
Survival
Gene Expression Profiling
Membrane Glycoproteins
23 Citations (Scopus)

Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma

Bonetti, P., Testoni, M., Scandurra, M., Ponzoni, M., Piva, R., Mensah, A. A., Rinaldi, A., Kwee, I., Tibiletti, M. G., Iqbal, J., Greiner, T. C., Chan, W. C., Gaidano, G., Piris, M. A., Cavalli, F., Zucca, E., Inghirami, G. & Bertoni, F., Jan 1 2013, In : Blood. 122, 13, p. 2233-2241 9 p.

Research output: Contribution to journalArticle

Deregulation
Lymphoma, Large B-Cell, Diffuse
Cells
Cell proliferation
Chromosomes
6 Citations (Scopus)

Differences in the cytogenetic alteration profiles of diffuse large B-cell lymphoma among Chinese and American patients

Chen, Y., Dave, B. J., Zhu, X., Chan, W. C., Iqbal, J., Sanger, W. G. & Fu, K., May 1 2013, In : Cancer Genetics. 206, 5, p. 183-190 8 p.

Research output: Contribution to journalArticle

Asian Americans
Lymphoma, Large B-Cell, Diffuse
Cytogenetics
B-Lymphocytes
Germinal Center
39 Citations (Scopus)

HACE1 is a tumor suppressor gene candidate in natural killer cell neoplasms

Küçük, C., Hu, X., Iqbal, J., Gaulard, P., Klinkebiel, D. L., Cornish, A., Dave, B. J. & Chan, W. C., Jan 1 2013, In : American Journal of Pathology. 182, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

Tumor Suppressor Genes
Natural Killer Cells
Neoplasms
Cytosine
Guanine
60 Citations (Scopus)

MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

Liu, C., Iqbal, J., Teruya-Feldstein, J., Shen, Y., Dabrowska, M. J., Dybkaer, K., Lim, M. S., Piva, R., Barreca, A., Pellegrino, E., Spaccarotella, E., Lachel, C. M., Kucuk, C., Jiang, C. S., Hu, X., Bhagavathi, S., Greiner, T. C., Weisenburger, D. D., Aoun, P., Perkins, S. L. & 3 others, McKeithan, T. W., Inghirami, G. & Chan, W. C., Jan 1 2013, In : Blood. 122, 12, p. 2083-2092 10 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
MicroRNAs
T-cells
Cluster Analysis
anaplastic lymphoma kinase
81 Citations (Scopus)

Molecular profiling improves classification and prognostication of nodal peripheral t-cell lymphomas: Results of a phase III diagnostic accuracy study

Piccaluga, P. P., Fuligni, F., De Leo, A., Bertuzzi, C., Rossi, M., Bacci, F., Sabattini, E., Agostinelli, C., Gazzola, A., Laginestra, M. A., Mannu, C., Sapienza, M. R., Hartmann, S., Hansmann, M. L., Piva, R., Iqbal, J., Chan, J. C., Weisenburger, D., Vose, J. M., Bellei, M. & 4 others, Federico, M., Inghirami, G., Zinzani, P. L. & Pileri, S. A., Aug 20 2013, In : Journal of Clinical Oncology. 31, 24, p. 3019-3025 7 p.

Research output: Contribution to journalArticle

T-Cell Lymphoma
Anaplastic Large-Cell Lymphoma
Lymphoma
Paraffin
Formaldehyde
2012
507 Citations (Scopus)

Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone

Johnson, N. A., Slack, G. W., Savage, K. J., Connors, J. M., Ben-Neriah, S., Rogic, S., Scott, D. W., Tan, K. L., Steidl, C., Sehn, L. H., Chan, W. C., Iqbal, J., Meyer, P. N., Lenz, G., Wright, G., Rimsza, L. M., Valentino, C., Brunhoeber, P., Grogan, T. M., Braziel, R. M. & 11 others, Cook, J. R., Tubbs, R. R., Weisenburger, D. D., Campo, E., Rosenwald, A., Ott, G., Delabie, J., Holcroft, C., Jaffe, E. S., Staudt, L. M. & Gascoyne, R. D., Oct 1 2012, In : Journal of Clinical Oncology. 30, 28, p. 3452-3459 8 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Vincristine
Prednisone
Doxorubicin
Cyclophosphamide

Follicular lymphoma: Recent advances

Bouska, A., Bagvati, S. K., Iqbal, J., William, B. M. & Chan, W. C., Jan 1 2012, Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics. Springer Netherlands, p. 21-42 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Follicular Lymphoma
B-Cell Lymphoma
B-Cell Leukemia
Germinal Center
Apoptosis
66 Citations (Scopus)

Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis

Iqbal, J., Shen, Y., Liu, Y., Fu, K., Jaffe, E. S., Liu, C., Liu, Z., Lachel, C. M., Deffenbacher, K., Greiner, T. C., Vose, J. M., Bhagavathi, S., Staudt, L. M., Rimsza, L., Rosenwald, A., Ott, G., Delabie, J., Campo, E., Braziel, R. M., Cook, J. R. & 6 others, Tubbs, R. R., Gascoyne, R. D., Armitage, J. O., Weisenburger, D. D., McKeithan, T. W. & Chan, W. C., May 24 2012, In : Blood. 119, 21, p. 4939-4948 10 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
MicroRNAs
Genes
Genome
Cyclin D1
64 Citations (Scopus)

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

Agnelli, L., Mereu, E., Pellegrino, E., Limongi, T., Kwee, I., Bergaggio, E., Ponzoni, M., Zamò, A., Iqbal, J., Piccaluga, P. P., Neri, A., Chan, W. C., Pileri, S., Bertoni, F., Inghirami, G. & Piva, R., Aug 9 2012, In : Blood. 120, 6, p. 1274-1281 8 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
T-cells
Identification (control systems)
Genes
T-Cell Lymphoma