Janina Baranowska-Kortylewicz, PhD

Professor

  • 1408 Citations
  • 22 h-Index
1985 …2019
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Research Output 1985 2019

  • 1408 Citations
  • 22 h-Index
  • 66 Article
  • 2 Comment/debate
  • 2 Review article
  • 1 Letter
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Article
2019
Carbamates
Radiotherapy
Glioblastoma
Neoplasms
Neuroblastoma
2018
1 Citation (Scopus)
Carbamates
Microtubules
Pharmaceutical Preparations
Positron emission tomography
Temperature
2017
3 Citations (Scopus)

Butyrylcholinesterase as a Blood Biomarker in Neuroblastoma

Coulter, D. W., Boettner, A. D., Kortylewicz, Z. P., Enke, S. P., Luther, J. A., Verma, V. & Baranowska-Kortylewicz, J., Jan 1 2017, In : Journal of Pediatric Hematology/Oncology. 39, 4, p. 272-281 10 p.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Neuroblastoma
Biomarkers
Heterografts
Liver
2015
1 Citation (Scopus)
Radiopharmaceuticals
Molecular Pathology
Androgen Receptors
Prostatic Neoplasms
Radiotherapy
2014
17 Citations (Scopus)

A nonhuman primate model of human radiation-induced venocclusive liver disease and hepatocyte injury

Yannam, G. R., Han, B., Setoyama, K., Yamamoto, T., Ito, R., Brooks, J. M., Guzman-Lepe, J., Galambos, C., Fong, J. V., Deutsch, M., Quader, M. A., Yamanouchi, K., Kabarriti, R., Mehta, K., Soto-Gutierrez, A., Roy-Chowdhury, J., Locker, J., Abe, M., Enke, C. A., Baranowska-Kortylewicz, J. & 3 others, Solberg, T. D., Guha, C. & Fox, I. J., Feb 1 2014, In : International Journal of Radiation Oncology Biology Physics. 88, 2, p. 404-411 8 p.

Research output: Contribution to journalArticle

primates
liver
Primates
Liver Diseases
Hepatocytes
3 Citations (Scopus)

Co-targeting androgen receptor and DNA for imaging and molecular radiotherapy of prostate cancer: In vitro studies

Han, G., Kortylewicz, Z. P., Enke, T. & Baranowska-Kortylewicz, J., Dec 1 2014, In : Prostate. 74, 16, p. 1634-1646 13 p.

Research output: Contribution to journalArticle

Molecular Imaging
Androgen Receptors
Prostatic Neoplasms
Radiotherapy
DNA
2012
10 Citations (Scopus)
Radiotherapy
Radioisotopes
Radiation
Butyrylcholinesterase
Neoplasms
2011
2 Citations (Scopus)

Activation of PDGFr-β signaling pathway after imatinib and radioimmunotherapy treatment in experimental pancreatic cancer

Abe, M., Kortylewicz, Z. P., Enke, C. A., Mack, E. & Baranowska-Kortylewicz, J., Jun 1 2011, In : Cancers. 3, 2, p. 2507-2515 9 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Pancreatic Neoplasms
Neoplasms
Heterografts
Therapeutics
2009
3 Citations (Scopus)

Radioiodinated agents for imaging multidrug resistant tumors

Kortylewicz, Z. P., Augustine, A. M., Nearman, J., McGarry, J. & Baranowska-Kortylewicz, J., Sep 18 2009, In : Medicinal Chemistry. 5, 2, p. 171-181 11 p.

Research output: Contribution to journalArticle

Multiple Drug Resistance
Heterografts
Neoplasms
Verapamil
Pharmaceutical Preparations
12 Citations (Scopus)
Androgen Receptors
Deoxyuridine
Neoplasms
Pharmaceutical Preparations
Sex Hormone-Binding Globulin
2008
36 Citations (Scopus)
Vascular Endothelial Growth Factor Receptor-2
Vascular Endothelial Growth Factor Receptor
Osteopontin
radiation therapy
Radiotherapy
2007
12 Citations (Scopus)
Radioimmunotherapy
Platelet-Derived Growth Factor Receptors
Pancreatic Neoplasms
Neoplasms
Heterografts
14 Citations (Scopus)

PDGFRβ and HIF-1α inhibition with imatinib and radioimmunotherapy of experimental prostate cancer

Kimura, Y., Inoue, K., Abe, M., Nearman, J. & Baranowska-Kortylewicz, J., Nov 2007, In : Cancer Biology and Therapy. 6, 11, p. 1763-1772 10 p.

Research output: Contribution to journalArticle

Open Access
Radioimmunotherapy
Prostatic Neoplasms
Neoplasms
Insulin-Like Growth Factor I
Extracellular Fluid
65 Citations (Scopus)

Prolonged Survival of Porcine Hepatocytes in Cynomolgus Monkeys

Nagata, H., Nishitai, R., Shirota, C., Zhang, J. L., Koch, C. A., Cai, J., Awwad, M., Schuurman, H. J., Christians, U., Abe, M., Baranowska-Kortylewicz, J., Platt, J. L. & Fox, I. J., Jan 2007, In : Gastroenterology. 132, 1, p. 321-329 9 p.

Research output: Contribution to journalArticle

Macaca fascicularis
Hepatocytes
Swine
Liver Failure
Heterologous Transplantation
2005
50 Citations (Scopus)

Effect of platelet-derived growth factor receptor-β inhibition with STI571 on radioimmunotherapy

Baranowska-Kortylewicz, J., Abe, M., Pietras, K., Kortylewicz, Z. P., Kurizaki, T., Nearman, J., Paulsson, J., Mosley, R. L., Enke, C. A. & Östman, A., Sep 1 2005, In : Cancer Research. 65, 17, p. 7824-7831 8 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Platelet-Derived Growth Factor Receptors
Neoplasms
Imatinib Mesylate
Antibodies
12 Citations (Scopus)

Engineering and characterization of a divalent single-chain Fv angiotensin II fusion construct of the monoclonal antibody CC49

Wittel, U. A., Jain, M., Goel, A., Baranowska-Kortylewicz, J., Kurizaki, T., Chauhan, S. C., Agrawal, D. K., Colcher, D. & Batra, S. K., Apr 1 2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 168-176 9 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Angiotensin II
Fusion reactions
Monoclonal Antibodies
Tumors
2004
7 Citations (Scopus)
Anaphylatoxins
Capillary Permeability
Prostaglandin-Endoperoxide Synthases
Nitric Oxide Synthase
Neutrophils
2003
6 Citations (Scopus)

Constructs of biotin mimetic peptide with CC49 single-chain Fv designed for tumor pretargeting

Pavlinkova, G., Batra, S. K., Colcher, D., Booth, B. J. M. & Baranowska-Kortylewicz, J., Mar 1 2003, In : Peptides. 24, 3, p. 353-362 10 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Streptavidin
Biotin
Radioimmunotherapy
Tumors
15 Citations (Scopus)

Radiolabeled constructs for evaluation of the asialoglycoprotein receptor status and hepatic functional reserves

Abe, M., Lai, J., Kortylewicz, Z. P., Nagata, H., Fox, I. J., Enke, C. A. & Baranowska-Kortylewicz, J., Sep 1 2003, In : Bioconjugate Chemistry. 14, 5, p. 997-1006 10 p.

Research output: Contribution to journalArticle

Asialoglycoprotein Receptor
Liver
Hepatocytes
Transplants
Chemical modification
2002
10 Citations (Scopus)

Potentiation of radioimmunotherapy with response-selective peptide agonist of human C5a

Kurizaki, T., Okazaki, S., Sanderson, S. D., Colcher, D., Enke, C. A., Tempero, M. A. & Baranowska-Kortylewicz, J., Jul 20 2002, In : Journal of Nuclear Medicine. 43, 7, p. 957-967 11 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Peptides
Neoplasms
Capillary Permeability
Adenocarcinoma
2001
67 Citations (Scopus)

99mTc-labeled divalent and tetravalent CC49 single-chain Fv's: Novel imaging agents for rapid in vivo localization of human colon carcinoma

Goel, A., Baranowska-Kortylewicz, J., Hinrichs, S. H., Wisecarver, J. L., Pavlinkova, G., Augustine, S., Colcher, D., Booth, B. J. M. & Batra, S. K., Jan 1 2001, In : Journal of Nuclear Medicine. 42, 10, p. 1519-1527 9 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Colon
Carcinoma
Neoplasms
Genetic Techniques
42 Citations (Scopus)

Single-dose versus fractionated radioimmunotherapy of human colon carcinoma xenografts using 131I-labeled multivalent CC49 single-chain Fvs1

Goel, A., Augustine, S., Baranowska-Kortylewicz, J., Colcher, D., Booth, B. J. M., Pavlinkova, G., Tempero, M. & Batra, S. K., Feb 12 2001, In : Clinical Cancer Research. 7, 1, p. 175-184 10 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Heterografts
Colon
Carcinoma
Therapeutics
2000
33 Citations (Scopus)

Divalent forms of CC49 single-chain antibody constructs in Pichia pastoris: Expression, purification, and characterization

Goel, A., Beresford, G. W., Colcher, D., Pavlinkova, G., Booth, B. J. M., Baranowska-Kortylewicz, J. & Batra, S. K., Jan 1 2000, In : Journal of Biochemistry. 127, 5, p. 829-836 8 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Pichia
Purification
Tumors
Bearings (structural)
101 Citations (Scopus)

Genetically engineered tetravalent single-chain Fv of the pancarcinoma monoclonal antibody CC49: Improved biodistribution and potential for therapeutic application

Goel, A., Colcher, D., Baranowska-Kortylewicz, J., Augustine, S., Booth, B. J. M., Pavlinkova, G. & Batra, S. K., Dec 15 2000, In : Cancer Research. 60, 24, p. 6964-6971 8 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Immunoglobulin G
Monoclonal Antibodies
alcohol oxidase
Half-Life
62 Citations (Scopus)

High-dose therapy with 90yttrium-labeled monoclonal antibody CC49: A phase I trial

Tempero, M., Leichner, P., Baranowska-Kortylewicz, J., Harrison, K., Augustine, S., Schlom, J., Anderson, J., Wisecarver, J. L. & Colcher, D., Aug 1 2000, In : Clinical Cancer Research. 6, 8, p. 3095-3102 8 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Immunoconjugates
Liver
Neoplasms
Therapeutics
1999
8 Citations (Scopus)

Tumor localization and systemic absorption of intravesical instillation of radio-iodinated iododeoxyuridine in patients with bladder cancer

Chiou, R. K., Dalrymple, G. V., Baranowska-Kortylewicz, J., Holdeman, K. P., Schneiderman, M. H., Harrison, K. A. & Taylor, R. J., Jul 1999, In : Journal of Urology. 162, 1, p. 58-62 5 p.

Research output: Contribution to journalArticle

Idoxuridine
Intravesical Administration
Radio
Urinary Bladder Neoplasms
Urinary Bladder
1998
41 Citations (Scopus)

5-[125I]iodo-2'-deoxyuridine in the radiotherapy of brain tumors in rats

Kassis, A. I., Wen, P. Y., Van Den Abbeele, A. D., Baranowska-Kortylewicz, J., Makrigiorgos, G. M., Metz, K. R., Matalka, K. Z., Cook, C. U., Sahu, S. K., Black, P. M. L. & Adelstein, S. J., Jul 1 1998, In : Journal of Nuclear Medicine. 39, 7, p. 1148-1154 7 p.

Research output: Contribution to journalArticle

Idoxuridine
Brain Neoplasms
Radiotherapy
Neoplasms
Gliosarcoma
47 Citations (Scopus)

Stabilization of vasoactive intestinal peptide by lipids

Gololobov, G., Noda, Y., Sherman, S., Rubinstein, I., Baranowska-Kortylewicz, J. & Paul, S., Jun 4 1998, In : Journal of Pharmacology and Experimental Therapeutics. 285, 2, p. 753-758 6 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
Lipids
Phosphatidylglycerols
Phospholipids
Circular Dichroism
1997
20 Citations (Scopus)

Antiidioptypic response against murine monoclonal antibodies reactive with tumor-associated antigen TAG-72

Blanco, I., Kawatsu, R., Harrison, K., Leichner, P., Augustine, S., Baranowska-Kortylewicz, J., Tempero, M. & Colcher, D., Feb 28 1997, In : Journal of Clinical Immunology. 17, 1, p. 96-106 11 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Antibodies, Monoclonal, Humanized
Gastrointestinal Neoplasms
Affinity Chromatography
Ovarian Neoplasms
40 Citations (Scopus)

Patient-specific dosimetry of indium-111- and yttrium-90-labeled monoclonal antibody CC49

Leichner, P. K., Akabani, G., Colcher, D., Harrison, K. A., Hawkins, W. G., Eckblade, M., Baranowska-Kortylewicz, J., Augustine, S. C., Wisecarver, J. L. & Tempero, M. A., Apr 26 1997, In : Journal of Nuclear Medicine. 38, 4, p. 512-516 5 p.

Research output: Contribution to journalArticle

Yttrium
Indium
Monoclonal Antibodies
Neoplasms
Single-Photon Emission-Computed Tomography
7 Citations (Scopus)

Prodrugs in site-selective delivery of radiopharmaceuticals

Baranowska-Kortylewicz, J., Kortylewicz, Z. P., Hoffman, D. & Dalrymple, G. V., Jul 3 1997, In : Quarterly Journal of Nuclear Medicine. 41, 2, p. 127-139 13 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Prodrugs
Idoxuridine
Radioimmunotherapy
Deoxyuridine
24 Citations (Scopus)

Strand breaks after the decay of iodine-125 in proximity to plasmid pBR322 DNA

Sahu, S. K., Kortylewicz, Z. P., Baranowska-Kortylewicz, J., Taube, R. A., Adelstein, S. J. & Kassis, A. I., Apr 17 1997, In : Radiation Research. 147, 4, p. 401-408 8 p.

Research output: Contribution to journalArticle

iodine 125
plasmids
iodine
Iodine
strands
1996
14 Citations (Scopus)

Biochemical modulation by 5-fluorouracil and 1-folinic acid of tumor uptake of intra-arterial 5-[123I] iodo-2′-deoxyuridine in patients with liver metastases from colorectal cancer

Mariani, G., Di Sacco, S., Bonini, R., Di Luca, L., Buralli, S., Bonora, D., Ricci, S., Baranowska-Kortylewicz, J., Adelstein, S. J., Falcone, A. & Kassis, A. I., Jan 1 1996, In : Acta Oncologica. 35, 7, p. 941-945 5 p.

Research output: Contribution to journalArticle

Open Access
Idoxuridine
Deoxyuridine
Leucovorin
Fluorouracil
Colorectal Neoplasms
4 Citations (Scopus)

Colon-specific Prodrugs of 5-radioiodo-2′-deoxyuridine

Baranowska-Kortylewicz, J., Kortylewicz, Z. P., Hoffman, D., Winoto, A., Lai, J. & Dalrymple, G. V., Jan 1 1996, In : Acta Oncologica. 35, 7, p. 959-964 6 p.

Research output: Contribution to journalArticle

Deoxyuridine
Prodrugs
Colon
Gastrointestinal Contents
Glycoside Hydrolases
29 Citations (Scopus)

Intratumoral administration of 5-[123I]iodo-2′ deoxyuridine in a patient with a brain tumor

Kassis, A. I., Tumeh, S. S., Wen, P. Y. C., Baranowska-Kortylewicz, J., Van Den Abbeele, A. D., Zimmerman, R. E., Carvalho, P. A., Garada, B. M., DeSisto, W. C., Bailey, N. O., Castronovo, F. P., Mariani, G., Black, P. M. L. & Adelstein, S. J., Apr 1 1996, In : Journal of Nuclear Medicine. 37, 4 SUPPL., p. 19S-22S

Research output: Contribution to journalArticle

Idoxuridine
Deoxyuridine
Brain Neoplasms
Glioma
Radiopharmaceuticals
1 Citation (Scopus)

On the safety of 5-[125I]iodo-2′-deoxyuridine. Preclinical evaluation in swine

Baranowska-Kortylewicz, J., Dalrymple, G. V., Harrison, K. A., Holdeman, K. P., Sharp, J. G., Cohen, S. M., Lieberman, R. P., Schneiderman, M. H., Clausen, S. R., Hoffman, D., Lai, J., Schneiderman, G. S. & Helseth, L., Jan 1 1996, In : Acta Oncologica. 35, 7, p. 925-933 9 p.

Research output: Contribution to journalArticle

Open Access
Deoxyuridine
Swine
Safety
Idoxuridine
Blood Cell Count
31 Citations (Scopus)

Tumor targeting by intra-arterial infusion of 5-[123I]iodo-2′-deoxyuridine in patients with liver metastases from colorectal cancer

Mariani, G., Di Sacco, S., Volterrani, D., Di Luca, L., Buralli, S., Di Stefano, R., Baranowska-Kortylewicz, J., Bonora, D., Matteucci, F., Ricci, S., Riccardo Bellina, C., Falcone, A., Salvadori, P. A., Mosca, F., Adelstein, S. J. & Kassis, A. I., Apr 1 1996, In : Journal of Nuclear Medicine. 37, 4 SUPPL., p. 22S-25S

Research output: Contribution to journalArticle

Intra Arterial Infusions
Deoxyuridine
Idoxuridine
Colorectal Neoplasms
Neoplasm Metastasis
15 Citations (Scopus)

Tumor-targeting potential of radioiodinated iododeoxyuridine in bladder cancer

Van Den Abbeele, A. D., Tutrone, R. F., Berman, R. M., Baranowska-Kortylewicz, J., Barclay, P. D., Richie, J. P., Adelstein, S. J. & Kassis, A. I., Feb 1 1996, In : Journal of Nuclear Medicine. 37, 2, p. 315-320 6 p.

Research output: Contribution to journalArticle

Idoxuridine
Urinary Bladder Neoplasms
Neoplasms
Urothelium
Autoradiography
14 Citations (Scopus)

Tumor uptake and mitotic activity pattern of 5-[125I]iodo-2′-deoxyuridine after intravesical infusion in patients with bladder cancer

Mariani, G., Collecchi, P., Baldassarri, S., Di Luca, L., Buralli, S., Fontanini, G., Baranowska-Kortylewicz, J., Adelstein, S. J. & Kassis, A. I., Apr 1 1996, In : Journal of Nuclear Medicine. 37, 4 SUPPL., p. 16S-19S

Research output: Contribution to journalArticle

Deoxyuridine
Idoxuridine
Urinary Bladder Neoplasms
Neoplasms
Urinary Bladder
1995
29 Citations (Scopus)

A fluorimetric method for the detection of copper-mediated hydroxyl free radicals in the immediate proximity of DNA

Makrigiorgos, G. M., Bump, E., Huang, C., Baranowska-Kortylewicz, J. & Kassis, A. I., Apr 1995, In : Free Radical Biology and Medicine. 18, 4, p. 669-678 10 p.

Research output: Contribution to journalArticle

Hydroxyl Radical
Free Radicals
Copper
Polylysine
DNA
3 Citations (Scopus)

Radiolabeling of antibodies for therapy and diagnosis.

Baranowska-Kortylewicz, J., Dalrymple, G. V., Quadri, S. M. & Harrison, K. A., 1995, In : Methods in molecular biology (Clifton, N.J.). 51, p. 423-439 17 p.

Research output: Contribution to journalArticle

Indium Radioisotopes
Yttrium Radioisotopes
Radioimmunodetection
Isotope Labeling
Radioimmunotherapy
17 Citations (Scopus)

The effect of Indium-111 decay on pBR322 DNA

Sahu, S. K., Kassis, A. I., Makrigiorgos, G. M., Baranowska-Kortylewicz, J. & Adelstein, S. J., Apr 5 1995, In : Radiation Research. 141, 2, p. 193-198 6 p.

Research output: Contribution to journalArticle

indium
Indium
deoxyribonucleic acid
deterioration
DNA
1994
9 Citations (Scopus)

Accessibility of nucleic acid-complexed biomolecules to hydroxyl radicals correlates with their conformation: A fluorescence polarization spectroscopy study

Makrigiorgos, G. M., Bump, E., Huang, C., Baranowska-Kortylewicz, J. & Kassis, A. I., Jan 1 1994, In : International Journal of Radiation Biology. 66, 3, p. 247-257 11 p.

Research output: Contribution to journalArticle

fluorescence emission spectroscopy
Fluorescence Polarization
Fluorescence Spectrometry
Nucleic acids
Anisotropy

A new three-step strategy using the avidin-biotin system for radioimaging tumours

Smith, S. V., Van den Abbeele, A. D., Baranowska-Kortylewicz, J., Jones, P. L., Lambrecht, R. M., Adelstein, S. J. & Kassis, A. L., Jan 1 1994, In : Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 392-394 3 p.

Research output: Contribution to journalArticle

Avidin
Biotin
Tumors
16 Citations (Scopus)

Quantification of radiation-induced hydroxyl radicals within nucleohistones using a molecular fluorescent probe

Makrigiorgos, G. M., Folkard, M., Huang, C., Bump, E., Baranowska-Kortylewicz, J., Sahu, S. K., Michael, B. D. & Kassis, A. I., May 27 1994, In : Radiation Research. 138, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

Molecular Probes
hydroxyl radicals
Fluorescent Dyes
histones
Hydroxyl Radical
9 Citations (Scopus)

Radiolabeled biotin amides from triazenyl precursors: Synthesis, binding, and in‐vivo properties

Kortylewicz, Z. P., Baranowska‐Kortylewicz, J., Adelstein, S. J., Carmel, A. D. & Kassis, A. I., Dec 1994, In : Journal of Labelled Compounds and Radiopharmaceuticals. 34, 12, p. 1129-1146 18 p.

Research output: Contribution to journalArticle

Biotin
Amides
Avidin
Sodium Iodide
Streptavidin
27 Citations (Scopus)

Radiolabeling kit/generator for 5‐radiohalogenated uridines

Baranowska-Kortylewicz, J., Helseth, L. D., Lai, J., Schneiderman, M. H., Schneiderman, G. S. & Dalrymple, G. V., Jun 1994, In : Journal of Labelled Compounds and Radiopharmaceuticals. 34, 6, p. 513-521 9 p.

Research output: Contribution to journalArticle

Bromine
Thin layer chromatography
Uridine
Bromodeoxyuridine
Nucleosides
1993
54 Citations (Scopus)

A method for detection of hydroxyl radicals in the vicinity of biomolecules using radiation-induced fluorescence of coumarin

Makrigiorgos, G. M., Baranowska-Kortylewicz, J., Bump, E., Sahu, S. K., Berman, R. M. & Kassis, A. I., Jan 1 1993, In : International Journal of Radiation Biology. 63, 4, p. 445-458 14 p.

Research output: Contribution to journalArticle

coumarin
hydroxyl radicals
Biomolecules
Hydroxyl Radical
Fluorescence
8 Citations (Scopus)

Labeling of Immunoglobulins with Bifunctional, Sulfhydryl-Selective, and Photoreactive Coumarins

Baranowska-Kortylewicz, J. & Kassis, A. I., Jul 1 1993, In : Bioconjugate Chemistry. 4, 4, p. 300-304 5 p.

Research output: Contribution to journalArticle

Coumarins
Alkylation
Hinges
Labeling
Immunoglobulins
2 Citations (Scopus)

Labeling of Sulfhydryl Groups in Intact Mammalian Cells with Coumarins

Baranowska-Kortylewicz, J. & Kassis, A. I., Jul 1 1993, In : Bioconjugate Chemistry. 4, 4, p. 305-307 3 p.

Research output: Contribution to journalArticle

Coumarins
Dithiothreitol
Labeling
Cells
Derivatives