Janina Baranowska-Kortylewicz, PhD &ndash; Research Output

2019

In vitro and in vivo evaluation of radiolabeled methyl N-[5-(3′-halobenzoyl)-1H-benzimidazol-2-yl]carbamate for cancer radiotherapy

Kortylewicz, Z. P., Coulter, D. W. & Baranowska-Kortylewicz, J., Jan 1 2019, (Accepted/In press) In : Drug Development Research.

Research output: Contribution to journal › Article

Carbamates

Radiotherapy

Glioblastoma

Neoplasms

Neuroblastoma

2018

1 Citation (Scopus)

Radiosynthesis of microtubule-targeted theranostic methyl N-[5-(3’-radiohalobenzoyl)-1H-benzimidazol-2-yl]carbamates

Kortylewicz, Z. P. & Baranowska-Kortylewicz, J., Aug 2018, In : Journal of Labelled Compounds and Radiopharmaceuticals. 61, 10, p. 749-756 8 p.

Research output: Contribution to journal › Article

Carbamates

Microtubules

Pharmaceutical Preparations

Positron emission tomography

Temperature

2017

3 Citations (Scopus)

Butyrylcholinesterase as a Blood Biomarker in Neuroblastoma

Coulter, D. W., Boettner, A. D., Kortylewicz, Z. P., Enke, S. P., Luther, J. A., Verma, V. & Baranowska-Kortylewicz, J., Jan 1 2017, In : Journal of Pediatric Hematology/Oncology. 39, 4, p. 272-281 10 p.

Research output: Contribution to journal › Article

Butyrylcholinesterase

Neuroblastoma

Biomarkers

Heterografts

Liver

2015

1 Citation (Scopus)

Preclinical evaluation of investigational radiopharmaceutical RISAD-pintended for use as a diagnostic and molecular radiotherapy agent for prostate cancer

Kortylewicz, Z. P., Mack, E., Enke, C. A., Estes, K. A., Mosley, R. L. & Baranowska-Kortylewicz, J., Jan 1 2015, In : Prostate. 75, 1, p. 8-22 15 p.

Research output: Contribution to journal › Article

Radiopharmaceuticals

Molecular Pathology

Androgen Receptors

Prostatic Neoplasms

Radiotherapy

2014

17 Citations (Scopus)

A nonhuman primate model of human radiation-induced venocclusive liver disease and hepatocyte injury

Yannam, G. R., Han, B., Setoyama, K., Yamamoto, T., Ito, R., Brooks, J. M., Guzman-Lepe, J., Galambos, C., Fong, J. V., Deutsch, M., Quader, M. A., Yamanouchi, K., Kabarriti, R., Mehta, K., Soto-Gutierrez, A., Roy-Chowdhury, J., Locker, J., Abe, M., Enke, C. A., Baranowska-Kortylewicz, J. & 3 others, Solberg, T. D., Guha, C. & Fox, I. J., Feb 1 2014, In : International Journal of Radiation Oncology Biology Physics. 88, 2, p. 404-411 8 p.

Research output: Contribution to journal › Article

primates

liver

Primates

Liver Diseases

Hepatocytes

3 Citations (Scopus)

Co-targeting androgen receptor and DNA for imaging and molecular radiotherapy of prostate cancer: In vitro studies

Han, G., Kortylewicz, Z. P., Enke, T. & Baranowska-Kortylewicz, J., Dec 1 2014, In : Prostate. 74, 16, p. 1634-1646 13 p.

Research output: Contribution to journal › Article

Molecular Imaging

Androgen Receptors

Prostatic Neoplasms

Radiotherapy

DNA

2012

10 Citations (Scopus)

Radiolabeled cyclosaligenyl monophosphates of 5-iodo-2′-deoxyuridine, 5-iodo-3′-fluoro-2′,3′-dideoxyuridine, and 3′-fluorothymidine for molecular radiotherapy of cancer: Synthesis and biological evaluation

Kortylewicz, Z. P., Kimura, Y., Inoue, K., MacK, E. & Baranowska-Kortylewicz, J., Mar 22 2012, In : Journal of Medicinal Chemistry. 55, 6, p. 2649-2671 23 p.

Research output: Contribution to journal › Article

Radiotherapy

Radioisotopes

Radiation

Butyrylcholinesterase

Neoplasms

2011

2 Citations (Scopus)

Activation of PDGFr-β signaling pathway after imatinib and radioimmunotherapy treatment in experimental pancreatic cancer

Abe, M., Kortylewicz, Z. P., Enke, C. A., Mack, E. & Baranowska-Kortylewicz, J., Jun 1 2011, In : Cancers. 3, 2, p. 2507-2515 9 p.

Research output: Contribution to journal › Article

Radioimmunotherapy

Pancreatic Neoplasms

Neoplasms

Heterografts

Therapeutics

6 Citations (Scopus)

Intraperitoneal radioimmunotherapy: Auger electron emitters for solid tumors

Baranowska-Kortylewicz, J., Apr 1 2011, In : Immunotherapy. 3, 4, p. 491-494 4 p.

Research output: Contribution to journal › Comment/debate

Radioimmunotherapy

Electrons

Carcinoma

Monoclonal Antibodies

Pseudomyxoma Peritonei

2009

Availability of molecular imaging and "personalized medicine.".

Baranowska-Kortylewicz, J. & Henriksen, J. B., Jan 1 2009, In : Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 50, 1, p. 16N

Research output: Contribution to journal › Comment/debate

Medical Economics

Precision Medicine

Molecular Imaging

Radiopharmaceuticals

Diagnostic Imaging

3 Citations (Scopus)

Radioiodinated agents for imaging multidrug resistant tumors

Kortylewicz, Z. P., Augustine, A. M., Nearman, J., McGarry, J. & Baranowska-Kortylewicz, J., Sep 18 2009, In : Medicinal Chemistry. 5, 2, p. 171-181 11 p.

Research output: Contribution to journal › Article

Multiple Drug Resistance

Heterografts

Neoplasms

Verapamil

Pharmaceutical Preparations

12 Citations (Scopus)

Radiolabeled 5-iodo-3′-O-(17β-succinyl-5α-androstan-3-one) -2′-deoxyuridine and its 5′-monophosphate for imaging and therapy of androgen receptor-positive cancers: Synthesis and biological evaluation

Kortylewicz, Z. P., Nearman, J. & Baranowska-Kortylewicz, J., Aug 27 2009, In : Journal of Medicinal Chemistry. 52, 16, p. 5124-5143 20 p.

Research output: Contribution to journal › Article

Androgen Receptors

Deoxyuridine

Neoplasms

Pharmaceutical Preparations

Sex Hormone-Binding Globulin

2008

36 Citations (Scopus)

Correlation Between Tumor Growth Delay and Expression of Cancer and Host VEGF, VEGFR2, and Osteopontin in Response to Radiotherapy

Solberg, T. D., Nearman, J., Mullins, J., Li, S. & Baranowska-Kortylewicz, J., Nov 1 2008, In : International Journal of Radiation Oncology Biology Physics. 72, 3, p. 918-926 9 p.

Research output: Contribution to journal › Article

Vascular Endothelial Growth Factor Receptor-2

Vascular Endothelial Growth Factor Receptor

Osteopontin

radiation therapy

Radiotherapy

2007

12 Citations (Scopus)

Emerging role of platelet-derived growth factor receptor-β inhibition in radioimmunotherapy of experimental pancreatic cancer

Baranowska-Kortylewicz, J., Abe, M., Nearman, J. & Enke, C. A., Jan 1 2007, In : Clinical Cancer Research. 13, 1, p. 299-306 8 p.

Research output: Contribution to journal › Article

Radioimmunotherapy

Platelet-Derived Growth Factor Receptors

Pancreatic Neoplasms

Neoplasms

Heterografts

14 Citations (Scopus)

PDGFRβ and HIF-1α inhibition with imatinib and radioimmunotherapy of experimental prostate cancer

Kimura, Y., Inoue, K., Abe, M., Nearman, J. & Baranowska-Kortylewicz, J., Nov 2007, In : Cancer Biology and Therapy. 6, 11, p. 1763-1772 10 p.

Research output: Contribution to journal › Article

Open Access

Radioimmunotherapy

Prostatic Neoplasms

Neoplasms

Insulin-Like Growth Factor I

Extracellular Fluid

65 Citations (Scopus)

Prolonged Survival of Porcine Hepatocytes in Cynomolgus Monkeys

Nagata, H., Nishitai, R., Shirota, C., Zhang, J. L., Koch, C. A., Cai, J., Awwad, M., Schuurman, H. J., Christians, U., Abe, M., Baranowska-Kortylewicz, J., Platt, J. L. & Fox, I. J., Jan 2007, In : Gastroenterology. 132, 1, p. 321-329 9 p.

Research output: Contribution to journal › Article

Macaca fascicularis

Hepatocytes

Swine

Liver Failure

Heterologous Transplantation

4 Citations (Scopus)

Radioactive drugs in drug development research: Quality assurance issues

Baranowska-Kortylewicz, J., Mar 1 2007, In : Mini-Reviews in Medicinal Chemistry. 7, 3, p. 231-244 14 p.

Research output: Contribution to journal › Review article

Quality assurance

Research

Pharmaceutical Preparations

Drug Compounding

Radiopharmaceuticals

2005

DNA uptake of ¹³¹I-iododeoxyuridine [3]

Baranowska-Kortylewicz, J. & Nearman, J., Dec 1 2005, In : Journal of Nuclear Medicine. 46, 5, p. 898-899 2 p.

Research output: Contribution to journal › Letter

Neoplastic Gene Expression Regulation

Iodine Radioisotopes

Antisense DNA

BALB 3T3 Cells

Isotope Labeling

50 Citations (Scopus)

Effect of platelet-derived growth factor receptor-β inhibition with STI571 on radioimmunotherapy

Baranowska-Kortylewicz, J., Abe, M., Pietras, K., Kortylewicz, Z. P., Kurizaki, T., Nearman, J., Paulsson, J., Mosley, R. L., Enke, C. A. & Östman, A., Sep 1 2005, In : Cancer Research. 65, 17, p. 7824-7831 8 p.

Research output: Contribution to journal › Article

Radioimmunotherapy

Platelet-Derived Growth Factor Receptors

Neoplasms

Imatinib Mesylate

Antibodies

12 Citations (Scopus)

Engineering and characterization of a divalent single-chain Fv angiotensin II fusion construct of the monoclonal antibody CC49

Wittel, U. A., Jain, M., Goel, A., Baranowska-Kortylewicz, J., Kurizaki, T., Chauhan, S. C., Agrawal, D. K., Colcher, D. & Batra, S. K., Apr 1 2005, In : Biochemical and Biophysical Research Communications. 329, 1, p. 168-176 9 p.

Research output: Contribution to journal › Article

Single-Chain Antibodies

Angiotensin II

Fusion reactions

Monoclonal Antibodies

Tumors

2004

7 Citations (Scopus)

Role of polymorphonuclear leukocytes, nitric oxide synthase, and cyclooxygenase in vascular permeability changes induced by C5a agonist peptides

Kurizaki, T., Abe, M., Sanderson, S. D., Enke, C. A. & Baranowska-Kortylewicz, J., Jan 1 2004, In : Molecular cancer therapeutics. 3, 1, p. 85-91 7 p.

Research output: Contribution to journal › Article

Anaphylatoxins

Capillary Permeability

Prostaglandin-Endoperoxide Synthases

Nitric Oxide Synthase

Neutrophils

2003

6 Citations (Scopus)

Constructs of biotin mimetic peptide with CC49 single-chain Fv designed for tumor pretargeting

Pavlinkova, G., Batra, S. K., Colcher, D., Booth, B. J. M. & Baranowska-Kortylewicz, J., Mar 1 2003, In : Peptides. 24, 3, p. 353-362 10 p.

Research output: Contribution to journal › Article

Single-Chain Antibodies

Streptavidin

Biotin

Radioimmunotherapy

Tumors

15 Citations (Scopus)

Radiolabeled constructs for evaluation of the asialoglycoprotein receptor status and hepatic functional reserves

Abe, M., Lai, J., Kortylewicz, Z. P., Nagata, H., Fox, I. J., Enke, C. A. & Baranowska-Kortylewicz, J., Sep 1 2003, In : Bioconjugate Chemistry. 14, 5, p. 997-1006 10 p.

Research output: Contribution to journal › Article

Asialoglycoprotein Receptor

Liver

Hepatocytes

Transplants

Chemical modification

2002

10 Citations (Scopus)

Potentiation of radioimmunotherapy with response-selective peptide agonist of human C5a

Kurizaki, T., Okazaki, S., Sanderson, S. D., Colcher, D., Enke, C. A., Tempero, M. A. & Baranowska-Kortylewicz, J., Jul 20 2002, In : Journal of Nuclear Medicine. 43, 7, p. 957-967 11 p.

Research output: Contribution to journal › Article

Radioimmunotherapy

Peptides

Neoplasms

Capillary Permeability

Adenocarcinoma

2001

67 Citations (Scopus)

^99mTc-labeled divalent and tetravalent CC49 single-chain Fv's: Novel imaging agents for rapid in vivo localization of human colon carcinoma

Goel, A., Baranowska-Kortylewicz, J., Hinrichs, S. H., Wisecarver, J. L., Pavlinkova, G., Augustine, S., Colcher, D., Booth, B. J. M. & Batra, S. K., Jan 1 2001, In : Journal of Nuclear Medicine. 42, 10, p. 1519-1527 9 p.

Research output: Contribution to journal › Article

Single-Chain Antibodies

Colon

Carcinoma

Neoplasms

Genetic Techniques

42 Citations (Scopus)

Single-dose versus fractionated radioimmunotherapy of human colon carcinoma xenografts using ¹³¹I-labeled multivalent CC49 single-chain Fvs¹

Goel, A., Augustine, S., Baranowska-Kortylewicz, J., Colcher, D., Booth, B. J. M., Pavlinkova, G., Tempero, M. & Batra, S. K., Feb 12 2001, In : Clinical Cancer Research. 7, 1, p. 175-184 10 p.

Research output: Contribution to journal › Article

Radioimmunotherapy

Heterografts

Colon

Carcinoma

Therapeutics

2000

33 Citations (Scopus)

Divalent forms of CC49 single-chain antibody constructs in Pichia pastoris: Expression, purification, and characterization

Goel, A., Beresford, G. W., Colcher, D., Pavlinkova, G., Booth, B. J. M., Baranowska-Kortylewicz, J. & Batra, S. K., Jan 1 2000, In : Journal of Biochemistry. 127, 5, p. 829-836 8 p.

Research output: Contribution to journal › Article

Single-Chain Antibodies

Pichia

Purification

Tumors

Bearings (structural)

101 Citations (Scopus)

Genetically engineered tetravalent single-chain Fv of the pancarcinoma monoclonal antibody CC49: Improved biodistribution and potential for therapeutic application

Goel, A., Colcher, D., Baranowska-Kortylewicz, J., Augustine, S., Booth, B. J. M., Pavlinkova, G. & Batra, S. K., Dec 15 2000, In : Cancer Research. 60, 24, p. 6964-6971 8 p.

Research output: Contribution to journal › Article

Single-Chain Antibodies

Immunoglobulin G

Monoclonal Antibodies

alcohol oxidase

Half-Life

62 Citations (Scopus)

High-dose therapy with ⁹⁰yttrium-labeled monoclonal antibody CC49: A phase I trial

Tempero, M., Leichner, P., Baranowska-Kortylewicz, J., Harrison, K., Augustine, S., Schlom, J., Anderson, J., Wisecarver, J. L. & Colcher, D., Aug 1 2000, In : Clinical Cancer Research. 6, 8, p. 3095-3102 8 p.

Research output: Contribution to journal › Article

Monoclonal Antibodies

Immunoconjugates

Liver

Neoplasms

Therapeutics

1999

8 Citations (Scopus)

Tumor localization and systemic absorption of intravesical instillation of radio-iodinated iododeoxyuridine in patients with bladder cancer

Chiou, R. K., Dalrymple, G. V., Baranowska-Kortylewicz, J., Holdeman, K. P., Schneiderman, M. H., Harrison, K. A. & Taylor, R. J., Jul 1999, In : Journal of Urology. 162, 1, p. 58-62 5 p.

Research output: Contribution to journal › Article

Idoxuridine

Intravesical Administration

Radio

Urinary Bladder Neoplasms

Urinary Bladder

1998

41 Citations (Scopus)

5-[¹²⁵I]iodo-2'-deoxyuridine in the radiotherapy of brain tumors in rats

Kassis, A. I., Wen, P. Y., Van Den Abbeele, A. D., Baranowska-Kortylewicz, J., Makrigiorgos, G. M., Metz, K. R., Matalka, K. Z., Cook, C. U., Sahu, S. K., Black, P. M. L. & Adelstein, S. J., Jul 1 1998, In : Journal of Nuclear Medicine. 39, 7, p. 1148-1154 7 p.

Research output: Contribution to journal › Article

Idoxuridine

Brain Neoplasms

Radiotherapy

Neoplasms

Gliosarcoma

47 Citations (Scopus)

Stabilization of vasoactive intestinal peptide by lipids

Gololobov, G., Noda, Y., Sherman, S., Rubinstein, I., Baranowska-Kortylewicz, J. & Paul, S., Jun 4 1998, In : Journal of Pharmacology and Experimental Therapeutics. 285, 2, p. 753-758 6 p.

Research output: Contribution to journal › Article

Vasoactive Intestinal Peptide

Lipids

Phosphatidylglycerols

Phospholipids

Circular Dichroism

1997

20 Citations (Scopus)

Antiidioptypic response against murine monoclonal antibodies reactive with tumor-associated antigen TAG-72

Blanco, I., Kawatsu, R., Harrison, K., Leichner, P., Augustine, S., Baranowska-Kortylewicz, J., Tempero, M. & Colcher, D., Feb 28 1997, In : Journal of Clinical Immunology. 17, 1, p. 96-106 11 p.

Research output: Contribution to journal › Article

Monoclonal Antibodies

Antibodies, Monoclonal, Humanized

Gastrointestinal Neoplasms

Affinity Chromatography

Ovarian Neoplasms

40 Citations (Scopus)

Patient-specific dosimetry of indium-111- and yttrium-90-labeled monoclonal antibody CC49

Leichner, P. K., Akabani, G., Colcher, D., Harrison, K. A., Hawkins, W. G., Eckblade, M., Baranowska-Kortylewicz, J., Augustine, S. C., Wisecarver, J. L. & Tempero, M. A., Apr 26 1997, In : Journal of Nuclear Medicine. 38, 4, p. 512-516 5 p.

Research output: Contribution to journal › Article

Yttrium

Indium

Monoclonal Antibodies

Neoplasms

Single-Photon Emission-Computed Tomography

7 Citations (Scopus)

Prodrugs in site-selective delivery of radiopharmaceuticals

Baranowska-Kortylewicz, J., Kortylewicz, Z. P., Hoffman, D. & Dalrymple, G. V., Jul 3 1997, In : Quarterly Journal of Nuclear Medicine. 41, 2, p. 127-139 13 p.

Research output: Contribution to journal › Article

Radiopharmaceuticals

Prodrugs

Idoxuridine

Radioimmunotherapy

Deoxyuridine

24 Citations (Scopus)

Strand breaks after the decay of iodine-125 in proximity to plasmid pBR322 DNA

Sahu, S. K., Kortylewicz, Z. P., Baranowska-Kortylewicz, J., Taube, R. A., Adelstein, S. J. & Kassis, A. I., Apr 17 1997, In : Radiation Research. 147, 4, p. 401-408 8 p.

Research output: Contribution to journal › Article

iodine 125

plasmids

iodine

Iodine

strands

1996

14 Citations (Scopus)

Biochemical modulation by 5-fluorouracil and 1-folinic acid of tumor uptake of intra-arterial 5-[¹²³I] iodo-2′-deoxyuridine in patients with liver metastases from colorectal cancer

Mariani, G., Di Sacco, S., Bonini, R., Di Luca, L., Buralli, S., Bonora, D., Ricci, S., Baranowska-Kortylewicz, J., Adelstein, S. J., Falcone, A. & Kassis, A. I., Jan 1 1996, In : Acta Oncologica. 35, 7, p. 941-945 5 p.

Research output: Contribution to journal › Article

Open Access

Idoxuridine

Deoxyuridine

Leucovorin

Fluorouracil

Colorectal Neoplasms

4 Citations (Scopus)

Colon-specific Prodrugs of 5-radioiodo-2′-deoxyuridine

Baranowska-Kortylewicz, J., Kortylewicz, Z. P., Hoffman, D., Winoto, A., Lai, J. & Dalrymple, G. V., Jan 1 1996, In : Acta Oncologica. 35, 7, p. 959-964 6 p.

Research output: Contribution to journal › Article

Deoxyuridine

Prodrugs

Colon

Gastrointestinal Contents

Glycoside Hydrolases

29 Citations (Scopus)

Intratumoral administration of 5-[¹²³I]iodo-2′ deoxyuridine in a patient with a brain tumor

Kassis, A. I., Tumeh, S. S., Wen, P. Y. C., Baranowska-Kortylewicz, J., Van Den Abbeele, A. D., Zimmerman, R. E., Carvalho, P. A., Garada, B. M., DeSisto, W. C., Bailey, N. O., Castronovo, F. P., Mariani, G., Black, P. M. L. & Adelstein, S. J., Apr 1 1996, In : Journal of Nuclear Medicine. 37, 4 SUPPL., p. 19S-22S

Research output: Contribution to journal › Article

Idoxuridine

Deoxyuridine

Brain Neoplasms

Glioma

Radiopharmaceuticals

1 Citation (Scopus)

On the safety of 5-[¹²⁵I]iodo-2′-deoxyuridine. Preclinical evaluation in swine

Baranowska-Kortylewicz, J., Dalrymple, G. V., Harrison, K. A., Holdeman, K. P., Sharp, J. G., Cohen, S. M., Lieberman, R. P., Schneiderman, M. H., Clausen, S. R., Hoffman, D., Lai, J., Schneiderman, G. S. & Helseth, L., Jan 1 1996, In : Acta Oncologica. 35, 7, p. 925-933 9 p.

Research output: Contribution to journal › Article

Open Access

Deoxyuridine

Swine

Safety

Idoxuridine

Blood Cell Count

8 Citations (Scopus)

Radiolabeled iododeoxyuridine: Safety evaluation

Harrison, K. A., Dalrymple, G. V., Baranowska-Kortylewicz, J., Holdeman, K. P., Schneiderman, M. H., Lieberman, R. P., Sharp, J. G., Cohen, S. M., Leichner, P. K., Augustine, S. C., Tempero, M. A., Taylor, R. J. & Chiou, R. K., Apr 1 1996, In : Journal of Nuclear Medicine. 37, 4 SUPPL., p. 13S-16S

Research output: Contribution to journal › Review article

Idoxuridine

Safety

Urinary Bladder

Swine

Liver

31 Citations (Scopus)

Tumor targeting by intra-arterial infusion of 5-[¹²³I]iodo-2′-deoxyuridine in patients with liver metastases from colorectal cancer

Mariani, G., Di Sacco, S., Volterrani, D., Di Luca, L., Buralli, S., Di Stefano, R., Baranowska-Kortylewicz, J., Bonora, D., Matteucci, F., Ricci, S., Riccardo Bellina, C., Falcone, A., Salvadori, P. A., Mosca, F., Adelstein, S. J. & Kassis, A. I., Apr 1 1996, In : Journal of Nuclear Medicine. 37, 4 SUPPL., p. 22S-25S

Research output: Contribution to journal › Article

Intra Arterial Infusions

Deoxyuridine

Idoxuridine

Colorectal Neoplasms

Neoplasm Metastasis

15 Citations (Scopus)

Tumor-targeting potential of radioiodinated iododeoxyuridine in bladder cancer

Van Den Abbeele, A. D., Tutrone, R. F., Berman, R. M., Baranowska-Kortylewicz, J., Barclay, P. D., Richie, J. P., Adelstein, S. J. & Kassis, A. I., Feb 1 1996, In : Journal of Nuclear Medicine. 37, 2, p. 315-320 6 p.

Research output: Contribution to journal › Article

Idoxuridine

Urinary Bladder Neoplasms

Neoplasms

Urothelium

Autoradiography

14 Citations (Scopus)

Tumor uptake and mitotic activity pattern of 5-[¹²⁵I]iodo-2′-deoxyuridine after intravesical infusion in patients with bladder cancer

Mariani, G., Collecchi, P., Baldassarri, S., Di Luca, L., Buralli, S., Fontanini, G., Baranowska-Kortylewicz, J., Adelstein, S. J. & Kassis, A. I., Apr 1 1996, In : Journal of Nuclear Medicine. 37, 4 SUPPL., p. 16S-19S

Research output: Contribution to journal › Article

Deoxyuridine

Idoxuridine

Urinary Bladder Neoplasms

Neoplasms

Urinary Bladder

1995

29 Citations (Scopus)

A fluorimetric method for the detection of copper-mediated hydroxyl free radicals in the immediate proximity of DNA

Makrigiorgos, G. M., Bump, E., Huang, C., Baranowska-Kortylewicz, J. & Kassis, A. I., Apr 1995, In : Free Radical Biology and Medicine. 18, 4, p. 669-678 10 p.

Research output: Contribution to journal › Article

Hydroxyl Radical

Free Radicals

Copper

Polylysine

DNA

3 Citations (Scopus)

Radiolabeling of antibodies for therapy and diagnosis.

Baranowska-Kortylewicz, J., Dalrymple, G. V., Quadri, S. M. & Harrison, K. A., 1995, In : Methods in molecular biology (Clifton, N.J.). 51, p. 423-439 17 p.

Research output: Contribution to journal › Article

Indium Radioisotopes

Yttrium Radioisotopes

Radioimmunodetection

Isotope Labeling

Radioimmunotherapy

17 Citations (Scopus)

The effect of Indium-111 decay on pBR322 DNA

Sahu, S. K., Kassis, A. I., Makrigiorgos, G. M., Baranowska-Kortylewicz, J. & Adelstein, S. J., Apr 5 1995, In : Radiation Research. 141, 2, p. 193-198 6 p.

Research output: Contribution to journal › Article

indium

Indium

deoxyribonucleic acid

deterioration

DNA

1994

9 Citations (Scopus)

Accessibility of nucleic acid-complexed biomolecules to hydroxyl radicals correlates with their conformation: A fluorescence polarization spectroscopy study

Makrigiorgos, G. M., Bump, E., Huang, C., Baranowska-Kortylewicz, J. & Kassis, A. I., Jan 1 1994, In : International Journal of Radiation Biology. 66, 3, p. 247-257 11 p.

Research output: Contribution to journal › Article

fluorescence emission spectroscopy

Fluorescence Polarization

Fluorescence Spectrometry

Nucleic acids

Anisotropy

A new three-step strategy using the avidin-biotin system for radioimaging tumours

Smith, S. V., Van den Abbeele, A. D., Baranowska-Kortylewicz, J., Jones, P. L., Lambrecht, R. M., Adelstein, S. J. & Kassis, A. L., Jan 1 1994, In : Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 392-394 3 p.

Research output: Contribution to journal › Article

Avidin

Biotin

Neoplasms

16 Citations (Scopus)

Quantification of radiation-induced hydroxyl radicals within nucleohistones using a molecular fluorescent probe

Makrigiorgos, G. M., Folkard, M., Huang, C., Bump, E., Baranowska-Kortylewicz, J., Sahu, S. K., Michael, B. D. & Kassis, A. I., May 27 1994, In : Radiation Research. 138, 2, p. 177-185 9 p.

Research output: Contribution to journal › Article

Molecular Probes

hydroxyl radicals

Fluorescent Dyes

histones

Hydroxyl Radical