Research Output per year
Research Output 2004 2019
Conformational studies of glucose transporter 1 (GLUT1) as an anticancer drug target
Almahmoud, S., Wang, X., Vennerstrom, J. L. & Zhong, H. A., Jun 7 2019, In : Molecules. 24, 11, 2159.Research output: Contribution to journal › Article
Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts
Daszynski, D. M., Santhoshkumar, P., Phadte, A. S., Sharma, K. K., Zhong, H. A., Lou, M. F. & Kador, P. F., Dec 1 2019, In : Scientific reports. 9, 1, 8459.Research output: Contribution to journal › Article
Ligand-based drug design: Synthesis and biological evaluation of substituted benzoin derivatives as potential antitumor agents
Sabbah, D. A., Ibrahim, A. H., Talib, W. H., Alqaisi, K. M., Sweidan, K., Bardaweel, S. K., Sheikha, G. A., Zhong, H. A., Al-Shalabi, E., Khalaf, R. A. & Mubarak, M. S., Jan 1 2019, In : Medicinal Chemistry. 15, 4, p. 417-429 13 p.Research output: Contribution to journal › Article
Molecular modeling studies on the binding mode of the PD-1/PD-L1 complex inhibitors
Almahmoud, S. & Zhong, H. A., Sep 2 2019, In : International journal of molecular sciences. 20, 18, 4654.Research output: Contribution to journal › Article
Benzoin schiff bases: Design, synthesis, and biological evaluation as potential antitumor agents
Sabbah, D. A., Al-Tarawneh, F., Talib, W. H., Sweidan, K., Bardaweel, S. K., Al-Shalabi, E., Zhong, H. A., Sheikha, G. A., Khalaf, R. A. & Mubarak, M. S., Jan 1 2018, In : Medicinal Chemistry. 14, 7, p. 695-708 14 p.Research output: Contribution to journal › Article
Free-Energy-Based Protein Design: Re-Engineering Cellular Retinoic Acid Binding Protein II Assisted by the Moveable-Type Approach
Zhong, H. A., Santos, E. M., Vasileiou, C., Zheng, Z., Geiger, J. H., Borhan, B. & Merz, K. M., Mar 14 2018, In : Journal of the American Chemical Society. 140, 10, p. 3483-3486 4 p.Research output: Contribution to journal › Article
Structure-based design: Synthesis, X-ray crystallography, and biological evaluation of N-substituted-4-hydroxy-2-quinolone-3-carboxamides as potential cytotoxic agents
Sabbah, D. A., Hishmah, B., Sweidan, K., Bardaweel, S., AlDamen, M., Zhong, H. A., Khalaf, R. A., Hasan Ibrahim, A., Al-Qirim, T., Abu Sheikha, G. & Mubarak, M. S., Jan 1 2018, In : Anti-Cancer Agents in Medicinal Chemistry. 18, 2, p. 263-276 14 p.Research output: Contribution to journal › Article
The simple system of fixing CO 2 to synthesize benzimidazolones at atmospheric pressure
Cao, X., Zhong, H. A., Zhang, P. & Zheng, H., Mar 2018, In : Journal of CO2 Utilization. 24, p. 250-255 6 p.Research output: Contribution to journal › Article
ADMET properties: Overview and current topics
Zhong, H. A., Aug 9 2017, Drug Design: Principles and Applications. Springer Singapore, p. 113-133 21 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer
Kumar, V., Chaudhary, A. K., Dong, Y., Zhong, H. A., Mondal, G., Lin, F., Kumar, V. & Mahato, R. I., Dec 1 2017, In : Scientific reports. 7, 1, 1665.Research output: Contribution to journal › Article
Simple synthesis of endophenazine G and other phenazines and their evaluation as anti-methicillin-resistant Staphylococcus aureus agents
Conda Sheridan, M., Udumula, V., Endres, J. L., Harper, C. N., Jaramillo, L., Zhong, H. A. & Bayles, K. W., Jan 1 2017, In : European Journal of Medicinal Chemistry. 125, p. 710-721 12 p.Research output: Contribution to journal › Article
Advances in drug discovery for the treatment of cancer: Many approaches, one goal
Bowen, J. P. & Zhong, H. A., May 1 2016, In : Current Topics in Medicinal Chemistry. 16, 13, p. 1411-1412 2 p.Research output: Contribution to journal › Editorial
Advances in the development of class I phosphoinositide 3-kinase (PI3K) inhibitors
Sabbah, D. A., Hu, J. & Zhong, H. A., May 1 2016, In : Current Topics in Medicinal Chemistry. 16, 13, p. 1413-1426 14 p.Research output: Contribution to journal › Review article
Drug design targeting the CXCR4/CXCR7/CXCL12 pathway
Xu, D., Li, R., Wu, J., Jiang, L. & Zhong, H. A., May 1 2016, In : Current Topics in Medicinal Chemistry. 16, 13, p. 1441-1451 11 p.Research output: Contribution to journal › Article
Methionine aminopeptidase type-2 inhibitors targeting angiogenesis
Ehlers, T., Furness, S., Robinson, T. P., Zhong, H. A., Goldsmith, D., Aribser, J. & Bowen, J. P., May 1 2016, In : Current Topics in Medicinal Chemistry. 16, 13, p. 1478-1488 11 p.Research output: Contribution to journal › Article
Modeling the protonation states of β-secretase binding pocket by molecular dynamics simulations and docking studies
Sabbah, D. A. & Zhong, H. A., Jul 1 2016, In : Journal of Molecular Graphics and Modelling. 68, p. 206-215 10 p.Research output: Contribution to journal › Article
Perspectives in medicinal chemistry: The evolution of medicinal chemistry
Phillip Bowen, J. & Zhong, H. A., Jan 1 2016, In : Current Topics in Medicinal Chemistry. 16, 9, p. 897-898 2 p.Research output: Contribution to journal › Article
Rational drug discovery, design, and development
Zhong, H. A., Güner, O. F. & Phillip, B. J., Sep 15 2016, Drug Delivery: Fundamentals and Applications: Second Edition. CRC Press, p. 443-464 22 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Molecular phylogeny and evolutionary dynamics of influenza A nonstructural (NS) gene
Xu, J., Zhong, H. A., Madrahimov, A., Helikar, T. & Lu, G., Mar 1 2014, In : Infection, Genetics and Evolution. 22, p. 192-200 9 p.Research output: Contribution to journal › Article
ADME and toxicity in early drug discovery
Zhong, H. A., Aug 15 2013, In : Current Topics in Medicinal Chemistry. 13, 11, p. 1255-1256 2 p.Research output: Contribution to journal › Editorial
Selectivity, binding affinity, and ionization state of matrix metalloproteinase inhibitors
Zhong, H. A., Arbiser, J. & Bowen, J. P., Aug 15 2013, In : Current Pharmaceutical Design. 19, 26, p. 4701-4713 13 p.Research output: Contribution to journal › Article
Synthesis and self-assembly of triphenylene-containing conjugated macrocycles
Dutta, T., Che, Y., Zhong, H. A., Laity, J. H., Dusevich, V., Murowchick, J. B., Zang, L. & Peng, Z., May 7 2013, In : RSC Advances. 3, 17, p. 6008-6015 8 p.Research output: Contribution to journal › Article
Understanding the molecular properties and metabolism of top prescribed drugs
Zhong, H. A., Mashinson, V., Woolman, T. A. & Zha, M., Aug 15 2013, In : Current Topics in Medicinal Chemistry. 13, 11, p. 1290-1307 18 p.Research output: Contribution to journal › Article
Binding selectivity studies of phosphoinositide 3-kinases using free energy calculations
Sabbah, D. A., Vennerstrom, J. L. & Zhong, H. A., Dec 21 2012, In : Journal of Chemical Information and Modeling. 52, 12, p. 3213-3224 12 p.Research output: Contribution to journal › Article
Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases
Sabbah, D. A., Simms, N. A., Brattain, M. G., Vennerstrom, J. L. & Zhong, H. A., Jan 15 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 2, p. 876-880 5 p.Research output: Contribution to journal › Article
Computational analysis of adaptive antigenic mutations of the human influenza hemagglutinin for vaccine strain selection
Rickert, J. D., Herpy, T. A., Zhong, H. A. & Lu, G., Mar 1 2012, In : International Journal of Bioinformatics Research and Applications. 8, 1-2, p. 81-98 18 p.Research output: Contribution to journal › Article
Evolutionary history and phylodynamics of influenza A and B neuraminidase (NA) genes inferred from large-scale sequence analyses
Xu, J., Davis, C. T., Christman, M. C., Rivailler, P., Zhong, H. A., Donis, R. O. & Lu, G., Jul 11 2012, In : PloS one. 7, 7, e38665.Research output: Contribution to journal › Article
N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα)
Sabbah, D. A., Simms, N. A., Wang, W., Dong, Y., Ezell, E. L., Brattain, M. G., Vennerstrom, J. L. & Zhong, H. A., Dec 15 2012, In : Bioorganic and Medicinal Chemistry. 20, 24, p. 7175-7183 9 p.Research output: Contribution to journal › Article
Synthesis and optical properties of perylene diimide derivatives with triphenylene-based dendrons linked at the bay positions through a conjugated ethynyl linkage
Bagui, M., Dutta, T., Zhong, H. A., Li, S., Chakraborty, S., Keightley, A. & Peng, Z., Apr 1 2012, In : Tetrahedron. 68, 13, p. 2806-2818 13 p.Research output: Contribution to journal › Article
Dual inhibitors of PI3K/mTOR or mTOR-selective inhibitors: Which way shall we go?
Sabbah, D. A., Brattain, M. G. & Zhong, H. A., Dec 1 2011, In : Current medicinal chemistry. 18, 36, p. 5528-5544 17 p.Research output: Contribution to journal › Article
Recent advances in small molecule inhibitors of VEGFR and EGFR signaling pathways
Zhong, H. A. & Phillip Bowen, J., Jun 1 2011, In : Current Topics in Medicinal Chemistry. 11, 12, p. 1571-1590 20 p.Research output: Contribution to journal › Review article
Synthesis and optical properties of triphenylene-based dendritic donor perylene diimide acceptor systems
Bagui, M., Dutta, T., Chakraborty, S., Melinger, J. S., Zhong, H. A., Keightley, A. & Peng, Z., Mar 10 2011, In : Journal of Physical Chemistry A. 115, 9, p. 1579-1592 14 p.Research output: Contribution to journal › Article
The impact of ionization states of matrix metalloproteinase inhibitors on docking-based inhibitor design
Zhong, H. A., Wees, M. A., Faure, T. D., Carrillo, C., Arbiser, J. & Bowen, J. P., Jun 9 2011, In : ACS Medicinal Chemistry Letters. 2, 6, p. 455-460 6 p.Research output: Contribution to journal › Article
Docking studies on isoform-specific inhibition of phosphoinositide-3- kinases
Sabbah, D. A., Vennerstrom, J. L. & Zhong, H. A., Oct 25 2010, In : Journal of Chemical Information and Modeling. 50, 10, p. 1887-1898 12 p.Research output: Contribution to journal › Article
Induced-fit docking studies of the active and inactive states of protein tyrosine kinases
Zhong, H. A., Tran, L. M. & Stang, J. L., Nov 1 2009, In : Journal of Molecular Graphics and Modelling. 28, 4, p. 336-346 11 p.Research output: Contribution to journal › Article
Binding free energy calculation for duocarmycin/DNA complex based on the QPLD-derived partial charge model
Zhong, H., Kirschner, K. N., Lee, M. & Bowen, J. P., Jan 15 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 2, p. 542-545 4 p.Research output: Contribution to journal › Article
Molecular design and clinical development of VEGFR kinase inhibitors
Zhong, H. & Bowen, J. P., Jul 1 2007, In : Current Topics in Medicinal Chemistry. 7, 14, p. 1379-1393 15 p.Research output: Contribution to journal › Review article
Small molecule inhibitors of the MDM2-p53 interaction discovered by ensemble-based receptor models
Bowman, A. L., Nikolovska-Coleska, Z., Zhong, H., Wang, S. & Carlson, H. A., Oct 24 2007, In : Journal of the American Chemical Society. 129, 42, p. 12809-12814 6 p.Research output: Contribution to journal › Article
Antiangiogenesis drug design: Multiple pathways targeting tumor vasculature
Zhong, H. & Bowen, J. P., Apr 1 2006, In : Current medicinal chemistry. 13, 8, p. 849-862 14 p.Research output: Contribution to journal › Review article
Conformational studies of polyprolines
Zhong, H. & Carlson, H. A., Dec 1 2006, In : Journal of Chemical Theory and Computation. 2, 2, p. 342-353 12 p.Research output: Contribution to journal › Article
Ab initio and DFT conformational studies of propanal, 2-butanone, and analogous imines and enamines
Zhong, H., Stewart, E. L., Kontoyianni, M. & Bowen, J. P., Dec 1 2005, In : Journal of Chemical Theory and Computation. 1, 2, p. 230-238 9 p.Research output: Contribution to journal › Article
Computational studies and peptidomimetic design for the human p53-MDM2 complex
Zhong, H. & Carlson, H. A., Jan 1 2005, In : Proteins: Structure, Function and Genetics. 58, 1, p. 222-234 13 p.Research output: Contribution to journal › Article
Theoretical study of stereoselective reduction controlled by NADH analogs
Zhong, H. & Bowen, J. P., Sep 1 2005, In : Journal of Molecular Graphics and Modelling. 24, 1, p. 1-9 9 p.Research output: Contribution to journal › Article
Structure and dynamics of a predicted ferredoxin-like selenoprotein in Japanese encephalitis virus
Zhong, H. & Taylor, E. W., Dec 1 2004, In : Journal of Molecular Graphics and Modelling. 23, 3, p. 223-231 9 p.Research output: Contribution to journal › Article