Ghribi Othman, PhD

Professor

  • 3144 Citations
  • 35 h-Index
1992 …2019
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Research Output 1992 2019

A Diet Enriched in Palmitate and Deficient in Linoleate Exacerbates Oxidative Stress and Amyloid-β Burden in the Hippocampus of 3xTg-AD Mouse Model of Alzheimer's Disease

Marwarha, G., Claycombe-Larson, K., Lund, J., Schommer, J. & Othman, G., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 1, p. 219-237 19 p.

Research output: Contribution to journalArticle

Palmitates
Linoleic Acid
Amyloid
Hippocampus
Alzheimer Disease
4 Citations (Scopus)

27-hydroxycholesterol decreases cell proliferation in colon cancer cell lines

Warns, J., Marwarha, G., Freking, N. & Othman, G., Jan 1 2018, (Accepted/In press) In : Biochimie.

Research output: Contribution to journalArticle

Cell proliferation
Colonic Neoplasms
Colorectal Neoplasms
Cholesterol
Cells
1 Citation (Scopus)

27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons

Schommer, J., Marwarha, G., Schommer, T., Flick, T., Lund, J. & Othman, G., Apr 3 2018, In : BMC Neuroscience. 19, 1, 17.

Research output: Contribution to journalArticle

Synucleins
Dopaminergic Neurons
HSP70 Heat-Shock Proteins
Proteins
Cholesterol
3 Citations (Scopus)

Palmitate-induced C/EBP homologous protein activation leads to NF-κB-mediated increase in BACE1 activity and amyloid beta genesis

Marwarha, G., Schommer, J., Lund, J., Schommer, T. & Othman, G., Jan 1 2018, (Accepted/In press) In : Journal of Neurochemistry.

Research output: Contribution to journalArticle

Transcription Factor CHOP
Palmitates
Amyloid
Chemical activation
Alzheimer Disease

Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis

Marwarha, G., Claycombe-Larson, K., Lund, J. & Othman, G., Jan 1 2018, (Accepted/In press) In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Palmitates
Response Elements
Sterols
Amyloid
Carrier Proteins