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Dominic E Cosgrove, PhD

Director

  • 4211 Citations
  • 32 h-Index
1987 …2021
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  • 2 Similar Profiles
Hereditary Nephritis Medicine & Life Sciences
Basement Membrane Medicine & Life Sciences
Glomerular Basement Membrane Medicine & Life Sciences
Usher Syndromes Medicine & Life Sciences
Collagen Type IV Medicine & Life Sciences
Integrins Medicine & Life Sciences
Cochlea Medicine & Life Sciences
Collagen Medicine & Life Sciences

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Projects 1992 2021

RESCUE OF ALPORT SYNDROME OTOPATHOLOGY

Cosgrove, D. E.

National Institutes of Health

2/3/16 → 1/31/21

Project: Research project

Hereditary Nephritis
Endothelin A Receptors
Basement Membrane
Laminin
Hearing Loss

USHERIN: STRUCTURAL AND FUNCTIONAL ANALYSIS

Cosgrove, D. E.

National Institutes of Health

4/1/01 → 6/30/13

Project: Research project

Usher Syndromes
Basement Membrane
Proteins
Deaf-Blind Disorders
Photoreceptor Cells

CORE CENTER

Morley, B. J., Neely, S. T., Gorga, M. P., Jesteadt, W., Cosgrove, D. E. & Moeller, M. P.

National Institutes of Health

9/1/00 → 8/31/16

Project: Research project

communication disorder
synergy
hardware
resources
research project

MOLECULAR ASPECTS OF ALPORT RENAL DISEASE PROGRESSION

Cosgrove, D. E. & Weintraub, B.

National Institutes of Health

4/15/99 → 8/31/14

Project: Research project

Disease Progression
Kidney
Hereditary Nephritis
Glomerular Basement Membrane
Matrix Metalloproteinases

MOUSE MODEL FOR AUTOSOMAL ALPORT SYNDROME

Cosgrove, D. E.

National Institutes of Health

5/1/96 → 4/30/00

Project: Research project

Hereditary Nephritis
Collagen
Basement Membrane
Mutation
Genes

Research Output 1987 2018

2 Citations (Scopus)

Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice

Cosgrove, D. E., Dufek, B., Meehan, D. T., Delimont, D., Hartnett, M., Samuelson, G., Gratton, M. A., Phillips, G., MacKenna, D. A. & Bain, G., Aug 1 2018, In : Kidney International. 94, 2, p. 303-314 12 p.

Research output: Contribution to journal › Article

Protein-Lysine 6-Oxidase
Fibrosis
Kidney
Glomerular Basement Membrane
Matrix Metalloproteinases
22 Citations (Scopus)

Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome

Cosgrove, D. E. & Liu, S., Apr 29 2016, (Accepted/In press) In : Matrix Biology.

Research output: Contribution to journal › Article

Hereditary Nephritis
Collagen Diseases
Glomerular Basement Membrane
Collagen Type IV
Basement Membrane
2 Citations (Scopus)

Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice

Meehan, D. T., Delimont, D., Dufek, B., Zallocchi, M. L., Phillips, G., Gratton, M. A. & Cosgrove, D. E., Nov 1 2016, In : Hearing Research. 341, p. 100-108 9 p.

Research output: Contribution to journal › Article

Endothelin-1
Extracellular Matrix
Basement Membrane
Pathology
Endothelin A Receptors
17 Citations (Scopus)

Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease

Dufek, B., Meehan, D. T., Delimont, D., Cheung, L., Gratton, M. A., Phillips, G., Song, W., Liu, S. & Cosgrove, D. E., Aug 1 2016, In : Kidney International. 90, 2, p. 300-310 11 p.

Research output: Contribution to journal › Article

Endothelin A Receptors
Glomerular Basement Membrane
Pseudopodia
Mesangial Cells
Metalloproteases
4 Citations (Scopus)

X-linked alport dogs demonstrate mesangial filopodial invasion of the capillary tuft as an early event in glomerular damage

Clark, S. D., Nabity, M. B., Cianciolo, R. E., Dufek, B. & Cosgrove, D. E., Dec 1 2016, In : PLoS One. 11, 12, e0168343.

Research output: Contribution to journal › Article

Hereditary Nephritis
Biopsy
Laminin
laminin
basement membrane