Dominic E Cosgrove, PhD

Director

  • 4099 Citations
  • 30 h-Index
1987 …2021
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  • 2 Similar Profiles
Hereditary Nephritis Medicine & Life Sciences
Basement Membrane Medicine & Life Sciences
Glomerular Basement Membrane Medicine & Life Sciences
Collagen Type IV Medicine & Life Sciences
Usher Syndromes Medicine & Life Sciences
Integrins Medicine & Life Sciences
Matrix Metalloproteinases Medicine & Life Sciences
Collagen Medicine & Life Sciences

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Projects 1992 2021

RESCUE OF ALPORT SYNDROME OTOPATHOLOGY

Cosgrove, D. E.

National Institutes of Health

2/3/161/31/21

Project: Research projectResearch Project

Hereditary Nephritis
Endothelin A Receptors
Basement Membrane
Laminin
Hearing Loss

USHERIN: STRUCTURAL AND FUNCTIONAL ANALYSIS

Cosgrove, D. E.

National Institutes of Health

4/1/016/30/13

Project: Research projectResearch Project

Usher Syndromes
Basement Membrane
Proteins
Deaf-Blind Disorders
Photoreceptor Cells
communication disorder
synergy
hardware
resources
research project

MOLECULAR ASPECTS OF ALPORT RENAL DISEASE PROGRESSION

Cosgrove, D. E. & Weintraub, B.

National Institutes of Health

4/15/998/31/14

Project: Research projectResearch Project

Disease Progression
Kidney
Hereditary Nephritis
Glomerular Basement Membrane
Matrix Metalloproteinases

MOUSE MODEL FOR AUTOSOMAL ALPORT SYNDROME

Cosgrove, D. E.

National Institutes of Health

5/1/964/30/00

Project: Research projectResearch Project

Hereditary Nephritis
Collagen
Basement Membrane
Mutation
Genes

Research Output 1987 2018

  • 4099 Citations
  • 30 h-Index
  • 76 Article

Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice

Cosgrove, D., Dufek, B., Meehan, D. T., Delimont, D., Hartnett, M., Samuelson, G., Gratton, M. A., Phillips, G., MacKenna, D. A. & Bain, G., Jan 1 2018, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Protein-Lysine 6-Oxidase
Fibrosis
Kidney
Glomerular Basement Membrane
Matrix Metalloproteinases
15 Citations

Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome

Cosgrove, D. & Liu, S., Apr 29 2016, (Accepted/In press) In : Matrix Biology.

Research output: Contribution to journalArticle

Hereditary Nephritis
Collagen Diseases
Glomerular Basement Membrane
Collagen Type IV
Basement Membrane
2 Citations

Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice

Meehan, D. T., Delimont, D., Dufek, B., Zallocchi, M., Phillips, G., Gratton, M. A. & Cosgrove, D., Nov 1 2016, In : Hearing Research. 341, p. 100-108 9 p.

Research output: Contribution to journalArticle

Endothelin-1
Extracellular Matrix
Basement Membrane
Pathology
Endothelin A Receptors
13 Citations

Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease

Dufek, B., Meehan, D. T., Delimont, D., Cheung, L., Gratton, M. A., Phillips, G., Song, W., Liu, S. & Cosgrove, D., Aug 1 2016, In : Kidney International. 90, 2, p. 300-310 11 p.

Research output: Contribution to journalArticle

Endothelin A Receptors
Glomerular Basement Membrane
Pseudopodia
Mesangial Cells
Metalloproteases
3 Citations

X-linked alport dogs demonstrate mesangial filopodial invasion of the capillary tuft as an early event in glomerular damage

Clark, S. D., Nabity, M. B., Cianciolo, R. E., Dufek, B. & Cosgrove, D., Dec 1 2016, In : PLoS One. 11, 12, e0168343.

Research output: Contribution to journalArticle

Hereditary Nephritis
Biopsy
Laminin
laminin
basement membrane