Diana F Florescu, MD

Associate Professor

  • 1509 Citations
  • 22 h-Index
20062019
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Research Output 2006 2019

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Article
2019

Adenovirus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

on behalf of the AST Infectious Diseases Community of Practice, Sep 1 2019, In : Clinical Transplantation. 33, 9, e13527.

Research output: Contribution to journalArticle

Adenoviridae
Communicable Diseases
Guidelines
Transplants
Adenoviridae Infections
2018
1 Citation (Scopus)

Adenovirus—A Deadly Disease in the Solid Organ Transplant Population: Risk Factors and Outcomes

Majorant, D., Qiu, F., Kalil, A. C., Wilson, N. & Florescu, D. F., Dec 2018, In : Transplantation Proceedings. 50, 10, p. 3769-3774 6 p.

Research output: Contribution to journalArticle

Adenoviridae
Transplants
Population
Asymptomatic Infections
Adenoviridae Infections

Invasive pneumococcal infections in pediatric liver-small bowel-pancreas transplant recipients

Vo, H. D., Florescu, D. F., Brown, C. R., Chambers, H. E., Mercer, D. F., Vargas, L. M., Grant, W. J., Langnas, A. N. & Quiros, R., May 2018, In : Pediatric Transplantation. 22, 3, e13165.

Research output: Contribution to journalArticle

Pneumococcal Infections
Pancreas
Sepsis
Pediatrics
Pneumonia
2 Citations (Scopus)

Meeting Report of the XIV International Small Bowel Transplant Symposium: Summary of Presentations, Workshops, and Debates From a Comprehensive Meeting on Intestinal Failure, Rehabilitation, and Transplantation, Buenos Aires, Argentina, June 10–13, 2015

Gondolesi, G. E., Fernandez, A., Burghardt, K. M., Nowakowski, S., Kaufman, S. S., Pascher, A., Florescu, D. F., Ruiz, P., Vianna, R., Clarke, S., Oltean, M., Rumbo, M., Mazariegos, G., Sudan, D. L. & Farmer, D. G., Feb 1 2018, In : Journal of Parenteral and Enteral Nutrition. 42, 2, p. 477-489 13 p.

Research output: Contribution to journalArticle

Argentina
Rehabilitation
Transplantation
Transplants
Education
Clostridium Infections
Clostridium difficile
Transplants
Infection
Proton Pump Inhibitors

Risk Factors for the Development of Cytomegalovirus Resistance in Solid Organ Transplantation: A Retrospective Case-Control Study

Sandkovsky, U., Qiu, F., Kalil, A. C., Florescu, A., Wilson, N., Manning, C. & Florescu, D. F., Dec 2018, In : Transplantation Proceedings. 50, 10, p. 3763-3768 6 p.

Research output: Contribution to journalArticle

Organ Transplantation
Cytomegalovirus
Case-Control Studies
Viremia
Antiviral Agents
2017
1 Citation (Scopus)

Clinical presentation and outcomes of norovirus infection in intestinal allograft compared to native intestine

Florescu, D. F., Sonderup, J. L., Grant, W., Chong, P. P., van Duin, D. & Kalil, A. C., Jun 2017, In : Transplant Infectious Disease. 19, 3, e12692.

Research output: Contribution to journalArticle

Norovirus
Intestines
Allografts
Odds Ratio
Gastroenteritis
3 Citations (Scopus)

Epidemiological investigation of Candida species causing bloodstream infection in paediatric small bowel transplant recipients

Suhr, M. J., Gomes-Neto, J. C., Banjara, N., Florescu, D. F., Mercer, D. F., Iwen, P. C. & Hallen-Adams, H. E., Jun 2017, In : Mycoses. 60, 6, p. 366-374 9 p.

Research output: Contribution to journalArticle

Candida
Pediatrics
Transplantation
Infection
caspofungin

Perioperative Prophylaxis for Total Artificial Heart Transplantation

Chambers, H. E., Pelish, P. L., Qiu, F. & Florescu, D. F., Nov 2017, In : Transplantation Proceedings. 49, 9, p. 2169-2175 7 p.

Research output: Contribution to journalArticle

Artificial Heart
Heart Transplantation
Infection
Pharmaceutical Preparations
Mortality
2016
1 Citation (Scopus)

Colistin, an old drug in a new territory, solid organ transplantation

Florescu, D. F., Mindru, C., Keck, M. A., Qiu, F. & Kalil, A. C., Jan 1 2016, In : Transplantation Proceedings. 48, 1, p. 152-157 6 p.

Research output: Contribution to journalArticle

Colistin
Hong Kong
Organ Transplantation
Pharmaceutical Preparations
Klebsiella oxytoca
Agammaglobulinemia
Passive Immunization
Immunoglobulin G
Survival
Cytomegalovirus
10 Citations (Scopus)

Predictors of persistent diarrhea in norovirus enteritis after solid organ transplantation

Chong, P. P., van Duin, D., Sonderup, J. L., Grant, W. J., Kalil, A. C. & Florescu, D. F., Nov 1 2016, In : Clinical Transplantation. 30, 11, p. 1488-1493 6 p.

Research output: Contribution to journalArticle

Norovirus
Enteritis
Organ Transplantation
Diarrhea
Cytomegalovirus Infections
2015
38 Citations (Scopus)

Administration of Brincidofovir and Convalescent Plasma in a Patient with Ebola Virus Disease

Florescu, D. F., Kalil, A. C., Hewlett, A. L., Schuh, A. J., Stroher, U., Uyeki, T. M. & Smith, P. W., Jun 8 2015, In : Clinical Infectious Diseases. 61, 6, p. 969-973 5 p.

Research output: Contribution to journalArticle

Ebola Hemorrhagic Fever
Investigational Therapies
Western Africa
Survival
cidofovir hexadecyloxypropyl ester
4 Citations (Scopus)

A randomized 2×2 factorial trial, Part 1: Single-dose rabbit antithymocyte globulin induction may improve renal transplantation outcomes

Stevens, R. B., Foster, K. W., Miles, C. D., Lane, J. T., Kalil, A. C., Florescu, D. F., Sandoz, J. P., Rigley, T. H., Nielsen, K. J., Skorupa, J. Y., Kellogg, A. M., Malik, T. & Wrenshall, L. E., Jan 15 2015, In : Transplantation. 99, 1, p. 197-209 13 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
Kidney Transplantation
Rabbits
Tacrolimus
Sirolimus
3 Citations (Scopus)
kidney transplant
immunosuppression
renal function
Grafts
histopathology
3 Citations (Scopus)

Cidofovir in pediatric solid organ transplant recipients: University of Nebraska experience

Florescu, D. F., Chambers, H. E., Qiu, F., Keck, M. A., Mercer, D. F., Morris, M. C. & Florescu, M. C., Jan 1 2015, In : Pediatric Infectious Disease Journal. 34, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

Pediatrics
Transplants
Renal Replacement Therapy
Nonparametric Statistics
Glomerular Filtration Rate
41 Citations (Scopus)
Sepsis
Confidence Intervals
Mortality
Transplants
Odds Ratio
76 Citations (Scopus)

The Use of TKM-100802 and Convalescent Plasma in 2 Patients with Ebola Virus Disease in the United States

Kraft, C. S., Hewlett, A. L., Koepsell, S. A., Winkler, A. M., Kratochvil, C. J., Larson, L., Varkey, J. B., Mehta, A. K., Lyon, G. M., Friedman-Moraco, R. J., Marconi, V. C., Hill, C. E., Sullivan, J. N., Johnson, D. W., Lisco, S. J., Mulligan, M. J., Uyeki, T. M., McElroy, A. K., Sealy, T., Campbell, S. & 236 others, Spiropoulou, C., Ströher, U., Crozier, I., Sacra, R., Connor, M. J., Sueblinvong, V., Franch, H. A., Smith, P. W., Ribner, B. S., Schwedhelm, S., Boulter, K., Beam, E. L., Gibbs, S., Lowe, J-M. J., Piquette, C. A., Bailey, K. L., Auxier, J., Boer, B., Hanson, T., Kaseman, J., Khan, M. S., Rhee, J. H., Wells, A., Florescu, D. F., Kalil, A. C., Rupp, M. E., Becker, V., Boeckman, B., Elder, E., Fitch, A., Flood, E., Freml, M., Frigge, R., Hanzlik, K. A., Jensen, L., Kraus, N., Molacek, D., Nevins, J., Parker, A., Peters, J., Rand, C., Roesler, K., Ryalls, K., Shradar, M., Strain, A., Sunderman, T., Sundermeier, J., Swanhorst, J., Vasa, A., Bellinghausen, J., Freihaut, F., Denny, S., Mainelli, L., Pinkney, D., Ray, D., Jevne, J., Knight, K., McCroy, D., Nadeau, R., Nightser, A., Iwen, P. C., Sambol, T., Herrera, V., Morgan, D., Trotter, S., Kerby, A., Peters, S., Southern, T., Murphy, C., Morris, R., Nuss, S., Franco, T., Ogden, C., Lazure, J., Straub, D., Hinrichs, S. H., Plumb, T. J., Florescu, M. C., Becker, J., Souchek, J., Beck, J., Heires, P., Gordon, B., Paulsen, G., Wolford, B., Petersen, J., Marion, N., Hayes, K., Tyner, K., Wilson, T., Baltes, P., Nowatzke, J., Nguyen, J., Turner, P., Boonstra, B., Jelden, K., Portrey, R., Stringfield, D., Scofield, B., Svanda, G., Horihan, J., Dahl, C., Bruno, M., Malm, K., Litz, R., Fehringer, J., Paladino, K., Opp, T., Bell, S., Adams, A., Allen, M. B., Bachman, R., Bornstein, W., Cantrell, D., Cosper, P., Feistritzer, N., Fox, J., Gartland, B., Goodman, J., Grant, S., Howard-Crow, D., Horowitz, I., Pugh, D., Ritenour, C., Ash, T., Barnes, C., Calhoun, J., Chapman, L., Daye, T., Durr, H., Evans, S., Gentry, J., Ginnane, J., Haynes, C., Hill, C., Hillis, D., Johnson, C., Loomis, J., Mamora, J., Mitchell, L., Morgan, J., Osakwe, N., Owen, J., Piazza, S., Shirley, K., Siddens, J., Silas, C., Slabach, J., Tirador, E., Todd, D., Vanairsdale, S., Brammer, N., Buchanan, J., Burd, E., Cardella, J., Eaves, B., Evans, C., Hostetler, K., Jenkins, K., Lindsey, M., Magee, J., Powers, R., Ritchie, J., Ryan, E., Bonds, S., Emamifar, A., Kuban, T., Pack, J., Rogers, S., Golston, G., Kaufman, S., Olinger, P., Olinger, S., Rengarajan, K., Thomaston, S., Beck, E., Desroches, P., Hall, C., Walker, C., Bryant, C., Hackman, B., Howard, R., Jones, M., Broughton, J., Frisle, B., Jackson, R., Lewis, J., Brown-Haithco, R., Gartin, M. L., Geralds-Washington, E., James-Jones, R., Miller, D., Stark, D., McGee, G., Jones, P., Scott-Harris, L., Cain, J., Davis, R., Johnson, T., Pickett, T., Shaw, A., Truesdale, T., Blum, J., Hill, L., Sevransky, J., Zivot, J., Walker, S., Klopman, M., Matkins, R., Meechan, C., Meechan, P., Schwock, K., Schuck, J., Stack, K., Wolf, F., Bray, B., Isakov, A., Shartar, S., Miles, W., Jamison, A., Arevalo, J., Stallings, G., Christenbury, J., Dollard, V., De Gennaro, M., Korschun, H., Seideman, N., Ziegler, T., Griffith, D. P., Dave, N., Wall, S., Hall, M., McGhee, D., Clarke, T., Vaught, R. & Peterson-Pileri, K., Aug 15 2015, In : Clinical Infectious Diseases. 61, 4, p. 496-502 7 p.

Research output: Contribution to journalArticle

Ebola Hemorrhagic Fever
Western Africa
Investigational Therapies
Renal Replacement Therapy
Artificial Respiration
2014
47 Citations (Scopus)

Adenovirus: Current epidemiology and emerging approaches to prevention and treatment

Sandkovsky, U., Vargas, L. M. & Florescu, D. F., Aug 2014, In : Current Infectious Disease Reports. 16, 8, 416.

Research output: Contribution to journalArticle

Adenoviridae
Epidemiology
Hematopoietic Stem Cells
Antiviral Agents
Transplants
42 Citations (Scopus)
Cytomegalovirus
Meta-Analysis
Odds Ratio
Confidence Intervals
Transplants
11 Citations (Scopus)

An international survey of cytomegalovirus prevention and treatment practices in intestinal transplantation

Florescu, D. F., Abu-Elmagd, K., Mercer, D. F., Qiu, F. & Kalil, A. C., Jan 15 2014, In : Transplantation. 97, 1, p. 78-82 5 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Transplantation
Foscarnet
Ganciclovir
Viremia
8 Citations (Scopus)

Does increasing immunoglobulin levels impact survival in solid organ transplant recipients with hypogammaglobulinemia?

Florescu, D. F., Kalil, A. C., Qiu, F., Grant, W., Morris, M. C., Schmidt, C. M., Florescu, M. C. & Poole, J. A., Nov 1 2014, In : Clinical Transplantation. 28, 11, p. 1249-1255 7 p.

Research output: Contribution to journalArticle

Agammaglobulinemia
Immunoglobulins
Immunoglobulin G
Transplants
Kidney
3 Citations (Scopus)
Interleukin-2 Receptors
Opportunistic Infections
Organ Transplantation
Meta-Analysis
Antibodies
1 Citation (Scopus)
Agammaglobulinemia
Intravenous Immunoglobulins
Organ Transplantation
Retrospective Studies
Immunoglobulin G
2013
51 Citations (Scopus)

Adenovirus in solid organ transplantation

Florescu, D. F. & Hoffman, J. A., Mar 1 2013, In : American Journal of Transplantation. 13, SUPPL.4, p. 206-211 6 p.

Research output: Contribution to journalArticle

Adenoviridae Infections
Cystitis
Opportunistic Infections
Organ Transplantation
Virus Diseases
1 Citation (Scopus)

Cytomegalovirus reactivation and colitis after left ventricular assist device placement

Sandkovsky, U., Florescu, D. F., Um, J. Y., Raichlin, E., Lowes, B. D., Kapalis, M., Hewlett, A., Duncan, K. F., Ryan, T., DiMaio, D. J., Wedel, W. & Kalil, A. C., May 1 2013, In : International Journal of Infectious Diseases. 17, 5, p. e348-e351

Research output: Contribution to journalArticle

Heart-Assist Devices
Colitis
Cytomegalovirus
Hemorrhage
32 Citations (Scopus)

What do we know about adenovirus in renal transplantation?

Florescu, M. C., Miles, C. D. & Florescu, D. F., Aug 1 2013, In : Nephrology Dialysis Transplantation. 28, 8, p. 2003-2010 8 p.

Research output: Contribution to journalArticle

Adenoviridae
Kidney Transplantation
Adenoviridae Infections
Cystitis
Kidney
69 Citations (Scopus)
Agammaglobulinemia
Organ Transplantation
Meta-Analysis
Survival Rate
Infection
2012
25 Citations (Scopus)

Incidence, risk factors, and outcomes associated with cytomegalovirus disease in small bowel transplant recipients

Florescu, D. F., Langnas, A. N., Grant, W., Mercer, D. F., Botha, J., Qiu, F., Shafer, L. & Kalil, A. C., May 1 2012, In : Pediatric Transplantation. 16, 3, p. 294-301 8 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Incidence
Enteritis
Transplantation
Opportunistic Infections
15 Citations (Scopus)
Blood Urea Nitrogen
Cystic Fibrosis
Colistin
Creatinine
Anti-Bacterial Agents
5 Citations (Scopus)

Pediococcus acidilactici endocarditis successfully treated with daptomycin

Iwen, P. C., Mindru, C., Kalil, A. C. & Florescu, D. F., Mar 1 2012, In : Journal of clinical microbiology. 50, 3, p. 1106-1108 3 p.

Research output: Contribution to journalArticle

Daptomycin
Intergenic DNA
Bacteremia
Endocarditis
Transplants
5 Citations (Scopus)
Respiratory Syncytial Viruses
Ribavirin
Respiratory Tract Infections
Pediatrics
Liver
2 Citations (Scopus)
Staphylococcus aureus
Transplantation
Infection
Mycophenolic Acid
Cytomegalovirus
9 Citations (Scopus)

Risk factors for systemic Candida infections in pediatric small bowel transplant recipients

Florescu, D. F., Qiu, F., Mercer, D. F., Langnas, A. N., Shafer, L. R. & Kalil, A. C., Feb 1 2012, In : Pediatric Infectious Disease Journal. 31, 2, p. 120-123 4 p.

Research output: Contribution to journalArticle

Fungemia
Transplantation
Pediatrics
Total Parenteral Nutrition
Candida
100 Citations (Scopus)

Safety and Efficacy of CMX001 as Salvage Therapy for Severe Adenovirus Infections in Immunocompromised Patients

Florescu, D. F., Pergam, S. A., Neely, M. N., Qiu, F., Johnston, C., Way, S., Sande, J., Lewinsohn, D. A., Guzman-Cottrill, J. A., Graham, M. L., Papanicolaou, G., Kurtzberg, J., Rigdon, J., Painter, W., Mommeja-Marin, H., Lanier, R., Anderson, M. & van der Horst, C., May 1 2012, In : Biology of Blood and Marrow Transplantation. 18, 5, p. 731-738 8 p.

Research output: Contribution to journalArticle

Adenoviridae Infections
Salvage Therapy
Immunocompromised Host
Safety
Adenoviridae
2 Citations (Scopus)
Pseudomonas aeruginosa
Transplantation
Pseudomonas
Kidney Transplantation
Pancreas
15 Citations (Scopus)

Staphylococcus aureus infections after liver transplantation

Florescu, D. F., McCartney, A. M., Qiu, F., Langnas, A. N., Botha, J., Mercer, D. F., Grant, W. & Kalil, A. C., Jun 1 2012, In : Infection. 40, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

Liver Transplantation
Staphylococcus aureus
Infection
Confidence Intervals
Odds Ratio
6 Citations (Scopus)

Staphylococcus aureus infections in kidney transplantation: A matched case controlled study

Florescu, D. F., Qiu, F., West, S. B., Richards, S., Florescu, M. C., Stevens, B., Hill, L. & Kalil, A. C., Jun 1 2012, In : Scandinavian Journal of Infectious Diseases. 44, 6, p. 427-432 6 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Staphylococcus aureus
Infection
Confidence Intervals
Steroids
2011
18 Citations (Scopus)

Clostridium difficile and cytomegalovirus colitis co-infection: Search for the hidden 'bug'

Florescu, D. F., Mindru, C., Chambers, H. E. & Kalil, A. C., Aug 1 2011, In : Transplant Infectious Disease. 13, 4, p. 411-415 5 p.

Research output: Contribution to journalArticle

Clostridium difficile
Colitis
Cytomegalovirus
Coinfection
19 Citations (Scopus)
Cytomegalovirus Infections
Immunocompromised Host
Intensive Care Units
Cytomegalovirus
Sepsis
43 Citations (Scopus)
Cytomegalovirus
Meta-Analysis
Transplantation
Therapeutics
Leukopenia
45 Citations (Scopus)

Is there a role for oral human immunoglobulin in the treatment for norovirus enteritis in immunocompromised patients?

Florescu, D. F., Hermsen, E. D., Kwon, J. Y., Gumeel, D., Grant, W. J., Mercer, D. F. & Kalil, A. C., Nov 1 2011, In : Pediatric Transplantation. 15, 7, p. 718-721 4 p.

Research output: Contribution to journalArticle

Norovirus
Enteritis
Immunocompromised Host
Immunoglobulins
Length of Stay
2010
40 Citations (Scopus)

Adenovirus infections in pediatric small bowel transplant recipients

Florescu, D. F., Islam, M. K., Mercer, D. F., Grant, W., Langnas, A. N., Freifeld, A. G., Sudan, D., Basappa, R., DiMaio, D. J. & Kalil, A. C., Jul 27 2010, In : Transplantation. 90, 2, p. 198-204 7 p.

Research output: Contribution to journalArticle

Adenoviridae Infections
Transplantation
Pediatrics
Adenoviridae
Cytomegalovirus
19 Citations (Scopus)

Incidence and outcome of fungal infections in pediatric small bowel transplant recipients

Florescu, D. F., Islam, K. M., Grant, W., Mercer, D. F., Langnas, A. N., Botha, J., Nielsen, B. & Kalil, A. C., Dec 1 2010, In : Transplant Infectious Disease. 12, 6, p. 497-504 8 p.

Research output: Contribution to journalArticle

Mycoses
Transplantation
Pediatrics
Intraabdominal Infections
Candida
6 Citations (Scopus)

Recommendations for the assessment and reporting of multivariable logistic regression in transplantation literature

Kalil, A. C., Mattei, J., Florescu, D. F., Sun, J. & Kalil, R. S., Jul 1 2010, In : American Journal of Transplantation. 10, 7, p. 1695-1703 9 p.

Research output: Contribution to journalArticle

Transplantation
Logistic Models
Transplants
Documentation
Patient Care
15 Citations (Scopus)

Recommendations for the assessment and reporting of multivariable logistic regression in transplantation literature

Kalil, A. C., Mattei, J., Florescu, D. F., Sun, J. & Kalil, R. S., Jul 1 2010, In : American Journal of Transplantation. 10, 7, p. 1686-1694 9 p.

Research output: Contribution to journalArticle

Transplantation
Logistic Models
Transplants
Documentation
Patient Care
7 Citations (Scopus)

The importance of detecting cytomegalovirus infections in studies evaluating new therapies for severe sepsis

Kalil, A. C., Sun, J. & Florescu, D. F., Oct 2010, In : Critical care medicine. 38, 10 SUPPL., p. S663-S667

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Sepsis
Protein C
Therapeutics
Mortality
2009
11 Citations (Scopus)

Cerebral aspergillosis caused by Aspergillus ustus following orthotopic heart transplantation: Case report and review of the literature

Florescu, D. F., Iwen, P. C., Hill, L. A., Dumitru, I., Quader, M. A., Kalil, A. C. & Freifeld, A. G., Apr 3 2009, In : Clinical Transplantation. 23, 1, p. 116-120 5 p.

Research output: Contribution to journalArticle

Aspergillosis
Aspergillus
Heart Transplantation
Immunocompromised Host
Fungi
44 Citations (Scopus)
Azithromycin
Cystic Fibrosis
Meta-Analysis
Pseudomonas
Nausea
4 Citations (Scopus)
Lung Abscess
Empyema
Enterococcus
Pneumonia
HIV