Diana F Florescu, MD

Associate Professor

  • 1509 Citations
  • 22 h-Index
20062019
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Research Output 2006 2019

2019

Adenovirus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

on behalf of the AST Infectious Diseases Community of Practice, Sep 1 2019, In : Clinical Transplantation. 33, 9, e13527.

Research output: Contribution to journalArticle

Adenoviridae
Communicable Diseases
Guidelines
Transplants
Adenoviridae Infections

Approach to infection and disease due to adenoviruses in solid organ transplantation

Florescu, D. F. & Stohs, E. J., Aug 1 2019, In : Current Opinion in Infectious Diseases. 32, 4, p. 300-306 7 p.

Research output: Contribution to journalReview article

Organ Transplantation
Adenoviridae
Transplants
Adenoviridae Infections
Infection
2018
1 Citation (Scopus)

Adenovirus—A Deadly Disease in the Solid Organ Transplant Population: Risk Factors and Outcomes

Majorant, D., Qiu, F., Kalil, A. C., Wilson, N. & Florescu, D. F., Dec 2018, In : Transplantation Proceedings. 50, 10, p. 3769-3774 6 p.

Research output: Contribution to journalArticle

Adenoviridae
Transplants
Population
Asymptomatic Infections
Adenoviridae Infections

Invasive pneumococcal infections in pediatric liver-small bowel-pancreas transplant recipients

Vo, H. D., Florescu, D. F., Brown, C. R., Chambers, H. E., Mercer, D. F., Vargas, L. M., Grant, W. J., Langnas, A. N. & Quiros, R., May 2018, In : Pediatric Transplantation. 22, 3, e13165.

Research output: Contribution to journalArticle

Pneumococcal Infections
Pancreas
Sepsis
Pediatrics
Pneumonia
2 Citations (Scopus)

Meeting Report of the XIV International Small Bowel Transplant Symposium: Summary of Presentations, Workshops, and Debates From a Comprehensive Meeting on Intestinal Failure, Rehabilitation, and Transplantation, Buenos Aires, Argentina, June 10–13, 2015

Gondolesi, G. E., Fernandez, A., Burghardt, K. M., Nowakowski, S., Kaufman, S. S., Pascher, A., Florescu, D. F., Ruiz, P., Vianna, R., Clarke, S., Oltean, M., Rumbo, M., Mazariegos, G., Sudan, D. L. & Farmer, D. G., Feb 1 2018, In : Journal of Parenteral and Enteral Nutrition. 42, 2, p. 477-489 13 p.

Research output: Contribution to journalArticle

Argentina
Rehabilitation
Transplantation
Transplants
Education
Clostridium Infections
Clostridium difficile
Transplants
Infection
Proton Pump Inhibitors

Risk Factors for the Development of Cytomegalovirus Resistance in Solid Organ Transplantation: A Retrospective Case-Control Study

Sandkovsky, U., Qiu, F., Kalil, A. C., Florescu, A., Wilson, N., Manning, C. & Florescu, D. F., Dec 2018, In : Transplantation Proceedings. 50, 10, p. 3763-3768 6 p.

Research output: Contribution to journalArticle

Organ Transplantation
Cytomegalovirus
Case-Control Studies
Viremia
Antiviral Agents
4 Citations (Scopus)

Severe infections in critically ill solid organ transplant recipients

Kalil, A. C., Sandkovsky, U. & Florescu, D. F., Dec 2018, In : Clinical Microbiology and Infection. 24, 12, p. 1257-1263 7 p.

Research output: Contribution to journalReview article

Critical Illness
Transplants
Infection
Epidemiology
Immunocompromised Host
2017
1 Citation (Scopus)

Clinical presentation and outcomes of norovirus infection in intestinal allograft compared to native intestine

Florescu, D. F., Sonderup, J. L., Grant, W., Chong, P. P., van Duin, D. & Kalil, A. C., Jun 2017, In : Transplant Infectious Disease. 19, 3, e12692.

Research output: Contribution to journalArticle

Norovirus
Intestines
Allografts
Odds Ratio
Gastroenteritis
3 Citations (Scopus)

Epidemiological investigation of Candida species causing bloodstream infection in paediatric small bowel transplant recipients

Suhr, M. J., Gomes-Neto, J. C., Banjara, N., Florescu, D. F., Mercer, D. F., Iwen, P. C. & Hallen-Adams, H. E., Jun 2017, In : Mycoses. 60, 6, p. 366-374 9 p.

Research output: Contribution to journalArticle

Candida
Pediatrics
Transplantation
Infection
caspofungin

Perioperative Prophylaxis for Total Artificial Heart Transplantation

Chambers, H. E., Pelish, P. L., Qiu, F. & Florescu, D. F., Nov 2017, In : Transplantation Proceedings. 49, 9, p. 2169-2175 7 p.

Research output: Contribution to journalArticle

Artificial Heart
Heart Transplantation
Infection
Pharmaceutical Preparations
Mortality
7 Citations (Scopus)

Sepsis and Challenging Infections in the Immunosuppressed Patient in the Intensive Care Unit

Florescu, D. F., Sandkovsky, U. & Kalil, A. C., Sep 2017, In : Infectious disease clinics of North America. 31, 3, p. 415-434 20 p.

Research output: Contribution to journalReview article

Intensive Care Units
Sepsis
Hematopoietic Stem Cell Transplantation
Organ Transplantation
Critical Care
1 Citation (Scopus)

The evaluation of critically ill transplant patients with infectious diarrhea

Florescu, D. F., Oct 1 2017, In : Current Opinion in Critical Care. 23, 5, p. 364-371 8 p.

Research output: Contribution to journalReview article

Critical Illness
Diarrhea
Transplants
Immunocompromised Host
Graft vs Host Disease
2016
1 Citation (Scopus)

Colistin, an old drug in a new territory, solid organ transplantation

Florescu, D. F., Mindru, C., Keck, M. A., Qiu, F. & Kalil, A. C., Jan 1 2016, In : Transplantation Proceedings. 48, 1, p. 152-157 6 p.

Research output: Contribution to journalArticle

Colistin
Hong Kong
Organ Transplantation
Pharmaceutical Preparations
Klebsiella oxytoca
Agammaglobulinemia
Passive Immunization
Immunoglobulin G
Survival
Cytomegalovirus
10 Citations (Scopus)

Predictors of persistent diarrhea in norovirus enteritis after solid organ transplantation

Chong, P. P., van Duin, D., Sonderup, J. L., Grant, W. J., Kalil, A. C. & Florescu, D. F., Nov 1 2016, In : Clinical Transplantation. 30, 11, p. 1488-1493 6 p.

Research output: Contribution to journalArticle

Norovirus
Enteritis
Organ Transplantation
Diarrhea
Cytomegalovirus Infections
2015
38 Citations (Scopus)

Administration of Brincidofovir and Convalescent Plasma in a Patient with Ebola Virus Disease

Florescu, D. F., Kalil, A. C., Hewlett, A. L., Schuh, A. J., Stroher, U., Uyeki, T. M. & Smith, P. W., Jun 8 2015, In : Clinical Infectious Diseases. 61, 6, p. 969-973 5 p.

Research output: Contribution to journalArticle

Ebola Hemorrhagic Fever
Investigational Therapies
Western Africa
Survival
cidofovir hexadecyloxypropyl ester
4 Citations (Scopus)

A randomized 2×2 factorial trial, Part 1: Single-dose rabbit antithymocyte globulin induction may improve renal transplantation outcomes

Stevens, R. B., Foster, K. W., Miles, C. D., Lane, J. T., Kalil, A. C., Florescu, D. F., Sandoz, J. P., Rigley, T. H., Nielsen, K. J., Skorupa, J. Y., Kellogg, A. M., Malik, T. & Wrenshall, L. E., Jan 15 2015, In : Transplantation. 99, 1, p. 197-209 13 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
Kidney Transplantation
Rabbits
Tacrolimus
Sirolimus
3 Citations (Scopus)
kidney transplant
immunosuppression
renal function
Grafts
histopathology
3 Citations (Scopus)

Cidofovir in pediatric solid organ transplant recipients: University of Nebraska experience

Florescu, D. F., Chambers, H. E., Qiu, F., Keck, M. A., Mercer, D. F., Morris, M. C. & Florescu, M. C., Jan 1 2015, In : Pediatric Infectious Disease Journal. 34, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

Pediatrics
Transplants
Renal Replacement Therapy
Nonparametric Statistics
Glomerular Filtration Rate
5 Citations (Scopus)

Fungal infections in intestinal and multivisceral transplant recipients

Florescu, D. F. & Sandkovsky, U., Jun 1 2015, In : Current opinion in organ transplantation. 20, 3, p. 295-302 8 p.

Research output: Contribution to journalReview article

Mycoses
Cryptococcus
Aspergillus
Mucorales
Invasive Candidiasis
41 Citations (Scopus)
Sepsis
Confidence Intervals
Mortality
Transplants
Odds Ratio

Reply to Thomason et al and Bahr et al

Kalil, A. C., Rupp, M. E. & Florescu, D. F., Jun 15 2015, In : Clinical Infectious Diseases. 60, 12, p. 1870-1871 2 p.

Research output: Contribution to journalLetter

Bacteremia
Transplant Recipients
14 Citations (Scopus)

The use and value of procalcitonin in solid organ transplantation

Sandkovsky, U., Kalil, A. C. & Florescu, D. F., Aug 1 2015, In : Clinical Transplantation. 29, 8, p. 689-696 8 p.

Research output: Contribution to journalReview article

Calcitonin
Organ Transplantation
Transplantation
Biomarkers
Transplants
76 Citations (Scopus)

The Use of TKM-100802 and Convalescent Plasma in 2 Patients with Ebola Virus Disease in the United States

Kraft, C. S., Hewlett, A. L., Koepsell, S. A., Winkler, A. M., Kratochvil, C. J., Larson, L., Varkey, J. B., Mehta, A. K., Lyon, G. M., Friedman-Moraco, R. J., Marconi, V. C., Hill, C. E., Sullivan, J. N., Johnson, D. W., Lisco, S. J., Mulligan, M. J., Uyeki, T. M., McElroy, A. K., Sealy, T., Campbell, S. & 236 others, Spiropoulou, C., Ströher, U., Crozier, I., Sacra, R., Connor, M. J., Sueblinvong, V., Franch, H. A., Smith, P. W., Ribner, B. S., Schwedhelm, S., Boulter, K., Beam, E. L., Gibbs, S., Lowe, J-M. J., Piquette, C. A., Bailey, K. L., Auxier, J., Boer, B., Hanson, T., Kaseman, J., Khan, M. S., Rhee, J. H., Wells, A., Florescu, D. F., Kalil, A. C., Rupp, M. E., Becker, V., Boeckman, B., Elder, E., Fitch, A., Flood, E., Freml, M., Frigge, R., Hanzlik, K. A., Jensen, L., Kraus, N., Molacek, D., Nevins, J., Parker, A., Peters, J., Rand, C., Roesler, K., Ryalls, K., Shradar, M., Strain, A., Sunderman, T., Sundermeier, J., Swanhorst, J., Vasa, A., Bellinghausen, J., Freihaut, F., Denny, S., Mainelli, L., Pinkney, D., Ray, D., Jevne, J., Knight, K., McCroy, D., Nadeau, R., Nightser, A., Iwen, P. C., Sambol, T., Herrera, V., Morgan, D., Trotter, S., Kerby, A., Peters, S., Southern, T., Murphy, C., Morris, R., Nuss, S., Franco, T., Ogden, C., Lazure, J., Straub, D., Hinrichs, S. H., Plumb, T. J., Florescu, M. C., Becker, J., Souchek, J., Beck, J., Heires, P., Gordon, B., Paulsen, G., Wolford, B., Petersen, J., Marion, N., Hayes, K., Tyner, K., Wilson, T., Baltes, P., Nowatzke, J., Nguyen, J., Turner, P., Boonstra, B., Jelden, K., Portrey, R., Stringfield, D., Scofield, B., Svanda, G., Horihan, J., Dahl, C., Bruno, M., Malm, K., Litz, R., Fehringer, J., Paladino, K., Opp, T., Bell, S., Adams, A., Allen, M. B., Bachman, R., Bornstein, W., Cantrell, D., Cosper, P., Feistritzer, N., Fox, J., Gartland, B., Goodman, J., Grant, S., Howard-Crow, D., Horowitz, I., Pugh, D., Ritenour, C., Ash, T., Barnes, C., Calhoun, J., Chapman, L., Daye, T., Durr, H., Evans, S., Gentry, J., Ginnane, J., Haynes, C., Hill, C., Hillis, D., Johnson, C., Loomis, J., Mamora, J., Mitchell, L., Morgan, J., Osakwe, N., Owen, J., Piazza, S., Shirley, K., Siddens, J., Silas, C., Slabach, J., Tirador, E., Todd, D., Vanairsdale, S., Brammer, N., Buchanan, J., Burd, E., Cardella, J., Eaves, B., Evans, C., Hostetler, K., Jenkins, K., Lindsey, M., Magee, J., Powers, R., Ritchie, J., Ryan, E., Bonds, S., Emamifar, A., Kuban, T., Pack, J., Rogers, S., Golston, G., Kaufman, S., Olinger, P., Olinger, S., Rengarajan, K., Thomaston, S., Beck, E., Desroches, P., Hall, C., Walker, C., Bryant, C., Hackman, B., Howard, R., Jones, M., Broughton, J., Frisle, B., Jackson, R., Lewis, J., Brown-Haithco, R., Gartin, M. L., Geralds-Washington, E., James-Jones, R., Miller, D., Stark, D., McGee, G., Jones, P., Scott-Harris, L., Cain, J., Davis, R., Johnson, T., Pickett, T., Shaw, A., Truesdale, T., Blum, J., Hill, L., Sevransky, J., Zivot, J., Walker, S., Klopman, M., Matkins, R., Meechan, C., Meechan, P., Schwock, K., Schuck, J., Stack, K., Wolf, F., Bray, B., Isakov, A., Shartar, S., Miles, W., Jamison, A., Arevalo, J., Stallings, G., Christenbury, J., Dollard, V., De Gennaro, M., Korschun, H., Seideman, N., Ziegler, T., Griffith, D. P., Dave, N., Wall, S., Hall, M., McGhee, D., Clarke, T., Vaught, R. & Peterson-Pileri, K., Aug 15 2015, In : Clinical Infectious Diseases. 61, 4, p. 496-502 7 p.

Research output: Contribution to journalArticle

Ebola Hemorrhagic Fever
Western Africa
Investigational Therapies
Renal Replacement Therapy
Artificial Respiration
2014
47 Citations (Scopus)

Adenovirus: Current epidemiology and emerging approaches to prevention and treatment

Sandkovsky, U., Vargas, L. M. & Florescu, D. F., Aug 2014, In : Current Infectious Disease Reports. 16, 8, 416.

Research output: Contribution to journalArticle

Adenoviridae
Epidemiology
Hematopoietic Stem Cells
Antiviral Agents
Transplants
42 Citations (Scopus)
Cytomegalovirus
Meta-Analysis
Odds Ratio
Confidence Intervals
Transplants
11 Citations (Scopus)

An international survey of cytomegalovirus prevention and treatment practices in intestinal transplantation

Florescu, D. F., Abu-Elmagd, K., Mercer, D. F., Qiu, F. & Kalil, A. C., Jan 15 2014, In : Transplantation. 97, 1, p. 78-82 5 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Transplantation
Foscarnet
Ganciclovir
Viremia
55 Citations (Scopus)

Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses

Florescu, D. F. & Keck, M. A., Oct 1 2014, In : Expert Review of Anti-Infective Therapy. 12, 10, p. 1171-1178 8 p.

Research output: Contribution to journalReview article

Viruses
Antiviral Agents
Lipids
Diphosphates
Biological Availability
8 Citations (Scopus)

Does increasing immunoglobulin levels impact survival in solid organ transplant recipients with hypogammaglobulinemia?

Florescu, D. F., Kalil, A. C., Qiu, F., Grant, W., Morris, M. C., Schmidt, C. M., Florescu, M. C. & Poole, J. A., Nov 1 2014, In : Clinical Transplantation. 28, 11, p. 1249-1255 7 p.

Research output: Contribution to journalArticle

Agammaglobulinemia
Immunoglobulins
Immunoglobulin G
Transplants
Kidney
3 Citations (Scopus)
Interleukin-2 Receptors
Opportunistic Infections
Organ Transplantation
Meta-Analysis
Antibodies
1 Citation (Scopus)
Agammaglobulinemia
Intravenous Immunoglobulins
Organ Transplantation
Retrospective Studies
Immunoglobulin G
14 Citations (Scopus)

The complex link between influenza and severe sepsis

Florescu, D. F. & Kalil, A. C., Jan 1 2014, In : Virulence. 5, 1, p. 137-142 6 p.

Research output: Contribution to journalReview article

Human Influenza
Sepsis
Orthomyxoviridae
Pandemics
Coinfection
2013
8 Citations (Scopus)

Adenovirus infections in heart transplantation

Florescu, D. F., Kwon, J. Y. & Dumitru, I., Jul 1 2013, In : Cardiology in review. 21, 4, p. 203-206 4 p.

Research output: Contribution to journalReview article

Adenoviridae Infections
Heart Transplantation
Adenoviridae
Ventricular Dysfunction
Immunocompromised Host
51 Citations (Scopus)

Adenovirus in solid organ transplantation

Florescu, D. F. & Hoffman, J. A., Mar 1 2013, In : American Journal of Transplantation. 13, SUPPL.4, p. 206-211 6 p.

Research output: Contribution to journalArticle

Adenoviridae Infections
Cystitis
Opportunistic Infections
Organ Transplantation
Virus Diseases
1 Citation (Scopus)

Cytomegalovirus reactivation and colitis after left ventricular assist device placement

Sandkovsky, U., Florescu, D. F., Um, J. Y., Raichlin, E., Lowes, B. D., Kapalis, M., Hewlett, A., Duncan, K. F., Ryan, T., DiMaio, D. J., Wedel, W. & Kalil, A. C., May 1 2013, In : International Journal of Infectious Diseases. 17, 5, p. e348-e351

Research output: Contribution to journalArticle

Heart-Assist Devices
Colitis
Cytomegalovirus
Hemorrhage
5 Citations (Scopus)

Opportunistic viral infections in intestinal transplantation

Florescu, D. F., Langnas, A. N. & Sandkovsky, U., Apr 1 2013, In : Expert Review of Anti-Infective Therapy. 11, 4, p. 367-381 15 p.

Research output: Contribution to journalReview article

Opportunistic Infections
Parenteral Nutrition
Organ Transplantation
Virus Diseases
Survival Rate
10 Citations (Scopus)
Sepsis
Investigational Therapies
Mortality
Placebos
Clinical Trials
32 Citations (Scopus)

What do we know about adenovirus in renal transplantation?

Florescu, M. C., Miles, C. D. & Florescu, D. F., Aug 1 2013, In : Nephrology Dialysis Transplantation. 28, 8, p. 2003-2010 8 p.

Research output: Contribution to journalArticle

Adenoviridae
Kidney Transplantation
Adenoviridae Infections
Cystitis
Kidney
69 Citations (Scopus)
Agammaglobulinemia
Organ Transplantation
Meta-Analysis
Survival Rate
Infection
2012
25 Citations (Scopus)

Bloodstream infections during the first year after pediatric small bowel transplantation

Florescu, D. F., Qiu, F., Langnas, A. N., Mercer, D. F., Chambers, H., Hill, L. A., Qaragholi, N. & Kalil, A. C., Jul 1 2012, In : Pediatric Infectious Disease Journal. 31, 7, p. 700-704 5 p.

Research output: Contribution to journalReview article

Transplantation
Pediatrics
Infection
Central Venous Catheters
Enterococcus
1 Citation (Scopus)

Can we predict cytomegalovirus reactivation in critically ill patients?

Florescu, D. F. & Kalil, A. C., Dec 1 2012, In : Critical care medicine. 40, 12, p. 3313-3314 2 p.

Research output: Contribution to journalEditorial

Virus Activation
Cytomegalovirus
Critical Illness
Natural Killer Cells
Interferons
25 Citations (Scopus)

Incidence, risk factors, and outcomes associated with cytomegalovirus disease in small bowel transplant recipients

Florescu, D. F., Langnas, A. N., Grant, W., Mercer, D. F., Botha, J., Qiu, F., Shafer, L. & Kalil, A. C., May 1 2012, In : Pediatric Transplantation. 16, 3, p. 294-301 8 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Incidence
Enteritis
Transplantation
Opportunistic Infections
33 Citations (Scopus)

Invasive Scopulariopsis brevicaulis infection in an immunocompromised patient and review of prior cases caused by Scopulariopsis and Microascus species

Iwen, P. C., Schutte, S. D., Florescu, D. F., Noel-Hurst, R. K. & Sigler, L., Aug 1 2012, In : Medical Mycology. 50, 6, p. 561-569 9 p.

Research output: Contribution to journalReview article

Scopulariopsis
Immunocompromised Host
Infection
infection
teleomorphs
15 Citations (Scopus)
Blood Urea Nitrogen
Cystic Fibrosis
Colistin
Creatinine
Anti-Bacterial Agents
5 Citations (Scopus)

Pediococcus acidilactici endocarditis successfully treated with daptomycin

Iwen, P. C., Mindru, C., Kalil, A. C. & Florescu, D. F., Mar 1 2012, In : Journal of clinical microbiology. 50, 3, p. 1106-1108 3 p.

Research output: Contribution to journalArticle

Daptomycin
Intergenic DNA
Bacteremia
Endocarditis
Transplants
5 Citations (Scopus)
Respiratory Syncytial Viruses
Ribavirin
Respiratory Tract Infections
Pediatrics
Liver
2 Citations (Scopus)
Staphylococcus aureus
Transplantation
Infection
Mycophenolic Acid
Cytomegalovirus
9 Citations (Scopus)

Risk factors for systemic Candida infections in pediatric small bowel transplant recipients

Florescu, D. F., Qiu, F., Mercer, D. F., Langnas, A. N., Shafer, L. R. & Kalil, A. C., Feb 1 2012, In : Pediatric Infectious Disease Journal. 31, 2, p. 120-123 4 p.

Research output: Contribution to journalArticle

Fungemia
Transplantation
Pediatrics
Total Parenteral Nutrition
Candida
23 Citations (Scopus)

Risk of cytomegalovirus disease in high-risk liver transplant recipients on valganciclovir prophylaxis: A systematic review and meta-Analysis

Kalil, A. C., Mindru, C., Botha, J. F., Grant, W. J., Mercer, D. F., Olivera-Martinez, M. A., McCartan, M. A., McCashland, T. M., Langnas, A. N. & Florescu, D. F., Dec 1 2012, In : Liver Transplantation. 18, 12, p. 1440-1447 8 p.

Research output: Contribution to journalReview article

Cytomegalovirus
Meta-Analysis
Liver
Confidence Intervals
Leukopenia