David W Mercer, MD

Chairperson

  • 2661 Citations
  • 29 h-Index
1988 …2018

Research output per year

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Research Output

  • 2661 Citations
  • 29 h-Index
  • 95 Article
  • 7 Review article
  • 5 Chapter
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Article
2002

Lipopolysaccharide-induced gastrointestinal injury in rats: Role of surface hydrophobicity and bile salts

Dial, E. J., Romero, J. J., Villa, X., Mercer, D. W. & Lichtenberger, L. M., Jan 2002, In : Shock. 17, 1, p. 77-80 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

Standardized patient care guidelines reduce infectious morbidity in appendectomy patients

Helmer, K. S., Robinson, E. K., Lally, K. P., Vasquez, J. C., Kwong, K. L., Liu, T. H. & Mercer, D. W., Jan 1 2002, In : American journal of surgery. 183, 6, p. 608-613 6 p.

Research output: Contribution to journalArticle

39 Scopus citations
2001

Image of the month

Liu, T. H., Mehall, J. R. & Mercer, D. W., Jan 1 2001, In : Archives of Surgery. 136, 12, p. 1437-1438 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Inducible nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults

Hassoun, H. T., Weisbrodt, N. W., Mercer, D. W., Kozar, R. A., Moody, F. G. & Moore, F. A., Jan 1 2001, In : Journal of Surgical Research. 97, 2, p. 150-154 5 p.

Research output: Contribution to journalArticle

76 Scopus citations

Lipopolysaccharide-induced gastroprotection is independent of the vagus nerve

Kim, Y. S., Chang, L. K. & Mercer, D. W., Jan 1 2001, In : Digestive Diseases and Sciences. 46, 7, p. 1526-1532 7 p., 342660.

Research output: Contribution to journalArticle

2 Scopus citations

Patient evaluation and management with selective use of magnetic resonance cholangiography and endoscopic retrograde cholangiopancreatography before laparoscopic cholecystectomy

Liu, T. H., Consorti, E. T., Kawashima, A., Tamm, E. P., Kwong, K. L., Gill, B. S., Sellin, J. H., Peden, E. K. & Mercer, D. W., Jul 18 2001, In : Annals of surgery. 234, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Post-injury multiple organ failure: The role of the gut

Hassoun, H. T., Kone, B. C., Mercer, D. W., Moody, F. G., Weisbrodt, N. W. & Moore, F. A., Jan 2001, In : Shock. 15, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

414 Scopus citations
2000

Effects of intestinal ischemia/reperfusion injury on gastric acid secretion

Castañeda, A., Vilela, R., Chang, L. & Mercer, D. W., May 1 2000, In : Journal of Surgical Research. 90, 1, p. 88-93 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Nitric oxide synthase inhibition negates bombesin-induced gastroprotection

Castañeda, A. A., Kim, Y. S., Chang, L. K., Cui, Y. & Mercer, D. W., Jan 1 2000, In : Surgery. 128, 3, p. 422-428 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
1999

Does upregulation of inducible nitric oxide synthase (iNOS) render the stomach more susceptible to damage?

Castañeda, A. A., Denning, J. W., Chang, L. & Mercer, D. W., Jun 15 1999, In : Journal of Surgical Research. 84, 2, p. 174-179 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Effects of endotoxin on regulation of intestinal smooth muscle nitric oxide synthase and intestinal transit

Cullen, J. J., Mercer, D., Hinkhouse, M., Ephgrave, K. S. & Conklin, J. L., Jan 1 1999, In : Surgery. 125, 3, p. 339-344 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

The efficacy of magnetic resonance cholangiography for the evaluation of patients with suspected choledocholithiasis before laparoscopic cholecystectomy

Liu, T. H., Consorti, E. T., Kawashima, A., Ernst, R. D., Black, C. T., Greger, P. H., Fischer, R. P. & Mercer, D. W., Dec 1 1999, In : American journal of surgery. 178, 6, p. 480-484 5 p.

Research output: Contribution to journalArticle

67 Scopus citations
1998

Bombesin prevents gastric injury in the rat: Role of gastrin

Mercer, D. W., Cross, J. M., Chang, L. & Lichtenberger, L. M., Apr 29 1998, In : Digestive Diseases and Sciences. 43, 4, p. 826-833 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21(Waf1/Cip1) and p27(Kip1)

Litvak, D. A., Evers, B. M., Hwang, K. O., Hellmich, M. R., Ko, T. C., Townsend, J., Mercer, D. W., Hodin, R. A., Postier, R. G. & Soybel, D. I., Jan 1 1998, In : Surgery. 124, 2, p. 161-170 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

Cyclooxygenase inhibition attenuates cholecystokinin-induced gastroprotection

Mercer, D. W., Smith, G. S. & Miller, T. A., Apr 18 1998, In : Digestive Diseases and Sciences. 43, 3, p. 468-475 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effects of Cholecystokinin on Gastric Injury and Gastric Mucosal Blood Flow

Cross, J. M., Chang, L. & Mercer, D. W., Jan 1 1998, In : Journal of Gastrointestinal Surgery. 2, 2, p. 198-206 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of endotoxin on gastric injury from luminal irritants in rats: Potential roles of nitric oxide

Mercer, D. W., Castaneda, A. A., Denning, J. W., Chang, L. & Russell, D. H., Sep 1 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 275, 3 38-3, p. G449-G459

Research output: Contribution to journalArticle

31 Scopus citations

Gastroprotective actions of bombesin L-DOPA, and mild irritants: Roles of prostaglandins and sensory neurons

Mercer, D. W., Cross, J. M., Castaneda, A. A. & Gunter, J. A., Jan 1 1998, In : Surgery. 124, 5, p. 864-870 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Store-operated calcium influx in human gastric cells: Role of endogenous prostaglandins

Kokoska, E. R., Smith, G. S., Miller, T. A., Mercer, D. W., Soybel, D. I. & Matthews, J. B., Jan 1 1998, In : Surgery. 124, 2, p. 429-437 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
1997

Effects of Dopamine and Alpha-2 Adrenoreceptor Blockade on L-Dopa and Cholecystokinin-Induced Gastroprotection

Cross, J. M., Mercer, D. W., Gunter, J. & Miller, T. A., Jan 1 1997, In : Journal of Gastrointestinal Surgery. 1, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Hypotension during Septic Shock Does Not Correlate with Plasma Levels of Nitric Oxide Metabolites in the Conscious Rat

Klemm, K., Mercer, D. W., Mailman, D. & Moody, F. G., Jan 1 1997, In : Journal of Gastrointestinal Surgery. 1, 4, p. 347-356 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Octreotide acetate attenuates bombesin induced gastroprotection

Mercer, D. W., Chang, L. & Lichtenberger, L. M., Dec 1 1997, In : FASEB Journal. 11, 3, p. A219

Research output: Contribution to journalArticle

Open-chest cardiac massage without major thoracotomy: Metabolic indicators of coronary and cerebral perfusion

Buckman, R. F., Badellino, M. M., Eynon, C. A., Mauro, L. H., Aldridge, S. C., Milner, R. E., Merchant, N. B., Buckman, R. F., Mercer, D., Malaspina, P. J. & Warren, R., Jun 1 1997, In : Resuscitation. 34, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Protective action of gastrin-17 against alcohol-induced gastric injury in the rat: Role in mucosal defense

Mercer, D. W., Cross, J. M., Smith, G. S. & Miller, T. A., Jan 1 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 273, 2 36-2, p. G365-G373

Research output: Contribution to journalArticle

29 Scopus citations
1996

Cholecystokinin-induced protection against gastric injury is independent of endogenous somatostatin

Mercer, D. W., Klemm, K., Cross, J. M., Smith, G. S., Cashman, M. & Miller, T. A., Oct 1 1996, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 271, 4 34-4, p. G692-G700

Research output: Contribution to journalArticle

28 Scopus citations

Effects of lipopolysaccharide on intestinal injury: Potential role of nitric oxide and lipid peroxidation

Mercer, D. W., Smith, G. S., Cross, J. M., Russell, D. H., Chang, L. & Cacioppo, J., Jun 1996, In : Journal of Surgical Research. 63, 1, p. 185-192 8 p.

Research output: Contribution to journalArticle

62 Scopus citations

Effects of polyunsaturated fatty acids on bile acid-induced gastric mucosal injury

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Feb 15 1996, In : Journal of Surgical Research. 61, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gastric injury induced by ethanol and Ischemia-Reperfusion in the rat: Differing roles for lipid peroxidation and oxygen radicals

Smith, G. S., Mercer, D. W., Cross, J. M., Barreto, J. C. & Miller, T. A., Jul 22 1996, In : Digestive Diseases and Sciences. 41, 6, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

55 Scopus citations
1995

Cholecystokinin is a potent protective agent against alcohol-induced gastric injury in the rat - Role of endogenous prostaglandins

Mercer, D. W., Cross, J. M., Barreto, J. C., Strobel, N. H. P., Russell, D. H. & Miller, T. A., Mar 1 1995, In : Digestive Diseases and Sciences. 40, 3, p. 651-660 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Isoproterenol-induced gastric mucosal protection from bile acid - Role of endogenous prostaglandins

Mercer, D. W., Merchant, N. B., Ritchie, W. P. & Dempsey, D. T., Oct 1 1995, In : Digestive Diseases and Sciences. 40, 10, p. 2227-2235 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Protective effect of a 21-aminosteroid against hemorrhage-induced ischemia-reperfusion injury in the rat stomach: role of lipid peroxidation.

Cross, J. M., Smith, G. S., Russell, D. H., Nguyen, P. H., Mercer, D. W., Barreto, J. C. & Miller, T. A., May 1 1995, In : Shock (Augusta, Ga.). 3, 5, p. 385-390 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Stimulation of Na+-K+-ATPase by thyrotropin in cultured thyroid follicular cells

Pressley, T. A., Higham, S. C., Joson, L. A. & Mercer, D. W., Jan 1 1995, In : American Journal of Physiology - Cell Physiology. 268, 5 37-5, p. C1252-C1258

Research output: Contribution to journalArticle

12 Scopus citations
1994

Bombesin maintains enterocyte phenotype in fasted rats

Hodin, R. A., Meng, S., Shei, A., Bass, B., Mercer, D. & Rudnicki, M., Jan 1 1994, In : Surgery. 116, 2, p. 426-431 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Capsaicin-induced gastric mucosal hyperemia and protection: The role of calcitonin gene-related peptide

Merchant, N. B., Dempsey, D. T., Grabowski, M. W., Rizzo, M., Ritchie, W. P., Bass, B., Mercer, D., Kellum, J. M. & Carvajal, S., Jan 1 1994, In : Surgery. 116, 2, p. 419-425 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Sensory neuron-mediated gastric mucosal protection is blocked by cyclooxygenase inhibition

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Jan 1 1994, In : Surgery. 115, 2, p. 156-163 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Topical prostaglandin e2 and isoproterenol reduce bile acid-induced gastric mucosal injury in shocked rats

Mercer, D. W., Kirshner, M. S., Ritchie, W. P. & Dempsey, D. T., Feb 1994, In : Journal of Surgical Research. 56, 2, p. 184-191 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
1993

Effects of topical isoproterenol on bile acid-induced gastric mucosal injury

Mercer, D. W., Podolsky, R. S., Ritchie, W. P. & Dempsey, D. T., Jan 1 1993, In : American Surgeon. 59, 8, p. 479-483 5 p.

Research output: Contribution to journalArticle

1992

Anatomic Considerations in Penetrating Gluteal Wounds

Mercer, D. W., Buckman, R. F., Sood, R., Kerr, T. M. & Gelman, J., Apr 1992, In : Archives of Surgery. 127, 4, p. 407-410 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Do leukotrienes mediate bile acid-induced gastric mucosal injury?

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Sep 30 1992, In : American Surgeon. 58, 9, p. 567-572 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Do sensory neurons mediate adaptive cytoprotection of gastric mucosa against bile acid injury?

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Jan 1992, In : The American Journal of Surgery. 163, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Selective lipoxygenase inhibitor reduces bile acid-induced gastric mucosal injury

Sullivan, T. R., Cordero, J. A., Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Dec 1992, In : Journal of Surgical Research. 53, 6, p. 568-571 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
1991

Leukotriene receptor blockade reduces bile acid-induced superficial gastric mucosal injury

Mercer, D. W., Milner, R., O'Neill, S., Ritchie, W. P. & Dempsey, D. T., Jun 1991, In : Journal of Surgical Research. 50, 6, p. 602-608 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Mediators of bile acid-induced alterations in gastric mucosal blood flow

Ritchie, W. P. & Mercer, D., Jan 1991, In : The American Journal of Surgery. 161, 1, p. 126-130 5 p.

Research output: Contribution to journalArticle

19 Scopus citations
1990

Adaptive cytoprotection of gastric surface epithelial cells against injury by physiologic concentrations of bile acid

Dempsey, D. T., Mercer, D. W., Deb, B., Sauter, A. & Ritchie, W. P., Jan 1 1990, In : Surgery. 108, 2, p. 348-355 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Topical leukotriene (LTC4) exacerbates bile acid injury to the superficial gastric mucosa in rats

Mercer, D. W., Milner, R. E., Kirshner, M. J., Ritchie, W. P. & Dempsey, D. T., Dec 1 1990, In : Surgical forum. 41, p. 138-139 2 p.

Research output: Contribution to journalArticle