David S Hage

  • 7858 Citations
  • 50 h-Index
1984 …2020
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Research Output 1984 2020

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Article
2020

Development of a microcolumn one-site immunometric assay for a protein biomarker: Analysis of alpha1-acid glycoprotein

Zhang, C., Lott, S., Clarke, W. & Hage, D. S., Jan 11 2020, In : Journal of Chromatography A. 1610, 460558.

Research output: Contribution to journalArticle

Biomarkers
Assays
Glycoproteins
Acids
Proteins
Open Access
Affinity chromatography
Affinity Chromatography
Serum Albumin
Pharmaceutical Preparations
Proteins
2019
3 Citations (Scopus)
Tolazamide
Affinity chromatography
Affinity Chromatography
Serum Albumin
Binding Sites

Development and evaluation of silica-based lectin microcolumns for glycoform analysis of alpha1-acid glycoprotein

Zhang, C. & Hage, D. S., Oct 31 2019, In : Analytica Chimica Acta. 1078, p. 189-199 11 p.

Research output: Contribution to journalArticle

Lectins
Silicon Dioxide
Glycoproteins
silica
Concanavalin A
1 Citation (Scopus)
Glycogen
Silicon Dioxide
Serum Albumin
Immobilization
Proteins
5 Citations (Scopus)

Testosterone meets albumin-the molecular mechanism of sex hormone transport by serum albumins

Czub, M. P., Venkataramany, B. S., Majorek, K. A., Handing, K. B., Porebski, P. J., Beeram, S. R., Suh, K., Woolfork, A. G., Hage, D. S., Shabalin, I. G. & Minor, W., Jan 1 2019, In : Chemical Science. 10, 6, p. 1607-1618 12 p.

Research output: Contribution to journalArticle

Open Access
Gonadal Steroid Hormones
Serum Albumin
Testosterone
Albumins
Blood
2018
1 Citation (Scopus)

Affinity extraction of emerging contaminants from water based on bovine serum albumin as a binding agent

Papastavros, E., Remmers, R. A., Snow, D. D., Cassada, D. A. & Hage, D. S., Mar 2018, In : Journal of Separation Science. 41, 5, p. 1074-1082 9 p.

Research output: Contribution to journalArticle

Bovine Serum Albumin
Sorbents
Impurities
Liquid chromatography
Water
1 Citation (Scopus)
Serum Albumin
Pharmaceutical Preparations
glimepiride
Rate constants
Glipizide
4 Citations (Scopus)

Characterization of solution-phase drug-protein interactions by ultrafast affinity extraction

Beeram, S. R., Zheng, X., Suh, K. & Hage, D. S., Aug 15 2018, In : Methods. 146, p. 46-57 12 p.

Research output: Contribution to journalArticle

Drug Interactions
Pharmaceutical Preparations
Rate constants
Proteins
Serum Albumin
3 Citations (Scopus)
Chlorpropamide
Serum Albumin
Medical problems
Pharmaceutical Preparations
Binding Sites
6 Citations (Scopus)

Peak decay analysis and biointeraction studies of immunoglobulin binding and dissociation on protein G affinity microcolumns

Anguizola, J. A., Pfaunmiller, E. L., Milanuk, M. L. & Hage, D. S., Aug 15 2018, In : Methods. 146, p. 39-45 7 p.

Research output: Contribution to journalArticle

Immunoglobulins
Immunoglobulin G
Regeneration
Proteins
Immobilized Proteins
5 Citations (Scopus)
piperine
Curcumin
Epithelial Cells
Proteins
Inflammation
2017
9 Citations (Scopus)
Drug interactions
Affinity chromatography
Drug Interactions
Affinity Chromatography
Blood Proteins
7 Citations (Scopus)

Chromatographic studies of drug interactions with alpha1-acid glycoprotein by ultrafast affinity extraction and peak profiling

Beeram, S., Bi, C., Zheng, X. & Hage, D. S., May 12 2017, In : Journal of Chromatography A. 1497, p. 92-101 10 p.

Research output: Contribution to journalArticle

Drug interactions
Drug Interactions
Glycoproteins
Acids
Pharmaceutical Preparations
25 Citations (Scopus)

Dual-target binding ligands with modulated pharmacokinetics for endoradiotherapy of prostate cancer

Kelly, J. M., Amor-Coarasa, A., Nikolopoulou, A., Wüstemann, T., Barelli, P., Kim, D., Williams, C., Zheng, X., Bi, C., Hu, B., Warren, J. D., Hage, D. S., Di Magno, S. G. & Babich, J. W., Sep 1 2017, In : Journal of Nuclear Medicine. 58, 9, p. 1442-1449 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Pharmacokinetics
Ligands
Serum Albumin
Kidney
7 Citations (Scopus)

Glycoform analysis of alpha1-acid glycoprotein based on capillary electrophoresis and electrophoretic injection

Zhang, C., Bi, C., Clarke, W. & Hage, D. S., Nov 10 2017, In : Journal of Chromatography A. 1523, p. 114-122 9 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Capillary Electrophoresis
Glycoproteins
Salt removal
Injections
5 Citations (Scopus)

Studies of drug interactions with alpha1-acid glycoprotein by using on-line immunoextraction and high-performance affinity chromatography

Bi, C., Matsuda, R., Zhang, C., Isingizwe, Z., Clarke, W. & Hage, D. S., Oct 13 2017, In : Journal of Chromatography A. 1519, p. 64-73 10 p.

Research output: Contribution to journalArticle

Drug interactions
Affinity chromatography
Drug Interactions
Affinity Chromatography
Glycoproteins
2016
7 Citations (Scopus)

Analysis of free drug fractions in human serum by ultrafast affinity extraction and two-dimensional affinity chromatography

Zheng, X., Podariu, M., Matsuda, R. & Hage, D. S., Jan 1 2016, In : Analytical and Bioanalytical Chemistry. 408, 1, p. 131-140 10 p.

Research output: Contribution to journalArticle

Affinity chromatography
Affinity Chromatography
Serum Albumin
Serum
Pharmaceutical Preparations
8 Citations (Scopus)
Affinity chromatography
Affinity Chromatography
Glycoproteins
Acids
Serum
7 Citations (Scopus)

Anisotropic contrast optical microscope

Peev, D., Hofmann, T., Kananizadeh, N., Beeram, S., Rodriguez, E., Wimer, S., Rodenhausen, K. B., Herzinger, C. M., Kasputis, T., Pfaunmiller, E., Nguyen, A., Korlacki, R., Pannier, A. K., Li, Y., Schubert, E., Hage, D. S. & Schubert, M., Nov 1 2016, In : Review of Scientific Instruments. 87, 11, 113701.

Research output: Contribution to journalArticle

optical microscopes
Microscopes
Ellipsometry
filters
Polarization
6 Citations (Scopus)
Chromatographic analysis
Serum Albumin
Chromatography
Fatty Acids
Tryptophan
14 Citations (Scopus)

Entrapment of alpha1-acid glycoprotein in high-performance affinity columns for drug-protein binding studies

Bi, C., Jackson, A., Vargas-Badilla, J., Li, R., Rada, G., Anguizola, J., Pfaunmiller, E. & Hage, D. S., May 15 2016, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1021, p. 188-196 9 p.

Research output: Contribution to journalArticle

Protein Binding
Glycoproteins
Acids
Pharmaceutical Preparations
Equilibrium constants
9 Citations (Scopus)

Glycoform analysis of alpha1-acid glycoprotein by capillary electrophoresis

Zhang, C. & Hage, D. S., Dec 2 2016, In : Journal of Chromatography A. 1475, p. 102-109 8 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Capillary Electrophoresis
Glycoproteins
Acids
Electroosmosis
9 Citations (Scopus)

On-column entrapment of alpha1-acid glycoprotein for studies of drug-protein binding by high-performance affinity chromatography

Anguizola, J., Bi, C., Koke, M., Jackson, A. & Hage, D. S., Aug 1 2016, In : Analytical and Bioanalytical Chemistry. 408, 21, p. 5745-5756 12 p.

Research output: Contribution to journalArticle

Affinity chromatography
Affinity Chromatography
Protein Binding
Glycoproteins
Acids

Optimizing sequence coverage for a moderate mass protein in nano-electrospray ionization quadrupole time-of-flight mass spectrometry

Matsuda, R., Kolli, V., Woods, M., Dodds, E. D. & Hage, D. S., Sep 15 2016, In : Analytical Biochemistry. 509, p. 115-117 3 p.

Research output: Contribution to journalArticle

Electrospray ionization
Mass spectrometry
Mass Spectrometry
Peptides
Proteins
4 Citations (Scopus)

Use of protein G microcolumns in chromatographic immunoassays: A comparison of competitive binding formats

Pfaunmiller, E. L., Anguizola, J. A., Milanuk, M. L., Carter, N. T. & Hage, D. S., May 15 2016, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1021, p. 91-100 10 p.

Research output: Contribution to journalArticle

Competitive Binding
Immunoassay
Serum Albumin
Limit of Detection
Injections
2015
11 Citations (Scopus)

Affinity chromatography: A historical perspective

Hage, D. S. & Matsuda, R., Jan 1 2015, In : Methods in Molecular Biology. 1286

Research output: Contribution to journalArticle

Affinity Chromatography
Complex Mixtures
Liquid Chromatography
Immobilization
9 Citations (Scopus)

Analysis of drug-protein binding using on-line immunoextraction and high-performance affinity microcolumns: Studies with normal and glycated human serum albumin

Matsuda, R., Jobe, D., Beyersdorf, J. & Hage, D. S., Oct 16 2015, In : Journal of Chromatography A. 1416, p. 112-120 9 p.

Research output: Contribution to journalArticle

Protein Binding
Serum Albumin
Pharmaceutical Preparations
Affinity chromatography
Proteins
10 Citations (Scopus)
Drug Interactions
Affinity Chromatography
Serum Albumin
Proteins
Liquid Chromatography
12 Citations (Scopus)

Analysis of glipizide binding to normal and glycated human serum albumin by high-performance affinity chromatography

Matsuda, R., Li, Z., Zheng, X. & Hage, D. S., Jul 28 2015, In : Analytical and Bioanalytical Chemistry. 407, 18, p. 5309-5321 13 p., 8688.

Research output: Contribution to journalArticle

Glipizide
Affinity chromatography
Affinity Chromatography
Serum Albumin
Pharmaceutical Preparations
12 Citations (Scopus)
Sex Hormone-Binding Globulin
Serum Albumin
Testosterone
Hormones
Equilibrium constants
19 Citations (Scopus)
glimepiride
Chromatography
Drug Interactions
Serum Albumin
Affinity chromatography
10 Citations (Scopus)

Development of enhanced capacity affinity microcolumns by using a hybrid of protein cross-linking/modification and immobilization

Zheng, X., Podariu, M., Bi, C. & Hage, D. S., Jun 26 2015, In : Journal of Chromatography A. 1400, p. 82-90 9 p.

Research output: Contribution to journalArticle

Immobilization
Serum Albumin
Proteins
Pharmaceutical Preparations
Ethacrynic Acid
2014
8 Citations (Scopus)

Analysis of drug interactions with very low density lipoprotein by high-performance affinity chromatography

Sobansky, M. R. & Hage, D. S., Oct 2014, In : Analytical and Bioanalytical Chemistry. 406, 25, p. 6203-6211 9 p.

Research output: Contribution to journalArticle

Drug interactions
Affinity chromatography
VLDL Lipoproteins
Drug Interactions
Affinity Chromatography
14 Citations (Scopus)
Drug Interactions
Serum Albumin
Pharmaceutical Preparations
Proteins
Medical problems
17 Citations (Scopus)

Clinical applications of capillary electrophoresis based immunoassays

Moser, A. C., Willicott, C. W. & Hage, D. S., Apr 2014, In : ELECTROPHORESIS. 35, 7, p. 937-955 19 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Capillary Electrophoresis
Immunoassay
Endocrinology
Clinical laboratories
33 Citations (Scopus)

Determination of rate constants and equilibrium constants for solution-phase drug-protein interactions by ultrafast affinity extraction

Zheng, X., Li, Z., Podariu, M. I. & Hage, D. S., Jul 1 2014, In : Analytical chemistry. 86, 13, p. 6454-6460 7 p.

Research output: Contribution to journalArticle

Equilibrium constants
Rate constants
Serum Albumin
Pharmaceutical Preparations
Proteins
6 Citations (Scopus)

Development of microcolumn-based one-site immunometric assays for protein biomarkers

Pfaunmiller, E. L., Anguizola, J. A., Milanuk, M. L., Papastavros, E., Carter, N. T., Matsuda, R., Zheng, X. & Hage, D. S., Oct 31 2014, In : Journal of Chromatography A. 1366, p. 92-100 9 p.

Research output: Contribution to journalArticle

Biomarkers
Serum Albumin
Assays
Proteins
Antibodies
9 Citations (Scopus)

Studies of drug interactions with glycated human serum albumin by high-performance affinity chromatography

Matsuda, R., Kye, S. H., Anguizola, J. & Hage, D. S., Aug 1 2014, In : Reviews in Analytical Chemistry. 33, 2, p. 79-94 16 p.

Research output: Contribution to journalArticle

Drug interactions
Affinity chromatography
Serum Albumin
Medical problems
Pharmaceutical Preparations
21 Citations (Scopus)

Studies of metabolite-protein interactions: A review

Matsuda, R., Bi, C., Anguizola, J., Sobansky, M., Rodriguez, E., Vargas Badilla, J., Zheng, X., Hage, B. & Hage, D. S., Sep 1 2014, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 966, p. 48-58 11 p.

Research output: Contribution to journalArticle

Metabolites
Proteins
Biochemical Phenomena
Metabolomics
Metabolic Diseases
2013
20 Citations (Scopus)

Analysis of free fractions for chiral drugs using ultrafast extraction and multi-dimensional high-performance affinity chromatography

Zheng, X., Yoo, M. J. & Hage, D. S., Nov 7 2013, In : Analyst. 138, 21, p. 6262-6265 4 p.

Research output: Contribution to journalArticle

Affinity chromatography
Enantiomers
Affinity Chromatography
chromatography
serum

An overview of CE in clinical analysis

Hage, D. S., 2013, In : Methods in Molecular Biology. 919, p. 3-10 8 p.

Research output: Contribution to journalArticle

Capillary Electrophoresis
Clinical Chemistry
Electrophoresis
Gels
42 Citations (Scopus)

Development of affinity microcolumns for drug-protein binding studies in personalized medicine: Interactions of sulfonylurea drugs with in vivo glycated human serum albumin

Anguizola, J., Joseph, K. S., Barnaby, O. S., Matsuda, R., Alvarado, G., Clarke, W., Cerny, R. & Hage, D. S., May 7 2013, In : Analytical chemistry. 85, 9, p. 4453-4460 8 p.

Research output: Contribution to journalArticle

Serum Albumin
Medicine
Pharmaceutical Preparations
Medical problems
Proteins
26 Citations (Scopus)

Use of entrapment and high-performance affinity chromatography to compare the binding of drugs and site-specific probes with normal and glycated human serum albumin

Jackson, A. J., Anguizola, J., Pfaunmiller, E. L. & Hage, D. S., Jul 1 2013, In : Analytical and Bioanalytical Chemistry. 405, 17, p. 5833-5841 9 p.

Research output: Contribution to journalArticle

Affinity chromatography
Affinity Chromatography
Serum Albumin
Binding Sites
Pharmaceutical Preparations
2012
41 Citations (Scopus)

Analysis of drug interactions with modified proteins by high-performance affinity chromatography: Binding of glibenclamide to normal and glycated human serum albumin

Matsuda, R., Anguizola, J., Joseph, K. S. & Hage, D. S., Nov 23 2012, In : Journal of Chromatography A. 1265, p. 114-122 9 p.

Research output: Contribution to journalArticle

Drug interactions
Affinity chromatography
Glyburide
Drug Interactions
Affinity Chromatography
19 Citations (Scopus)

Biointeraction analysis of immobilized antibodies and related agents by high-performance immunoaffinity chromatography

Pfaunmiller, E., Moser, A. C. & Hage, D. S., Feb 1 2012, In : Methods. 56, 2, p. 130-135 6 p.

Research output: Contribution to journalArticle

Immobilized Antibodies
Chromatography
Kinetics
Thermodynamics
Silicon Dioxide
15 Citations (Scopus)
Drug interactions
Affinity chromatography
Drug Interactions
Affinity Chromatography
LDL Lipoproteins
36 Citations (Scopus)

Optimization of human serum albumin monoliths for chiral separations and high-performance affinity chromatography

Pfaunmiller, E. L., Hartmann, M., Dupper, C. M., Soman, S. & Hage, D. S., Dec 21 2012, In : Journal of Chromatography A. 1269, p. 198-207 10 p.

Research output: Contribution to journalArticle

Affinity chromatography
Affinity Chromatography
Serum Albumin
Immobilization
Proteins
2011
61 Citations (Scopus)

Binding of tolbutamide to glycated human serum albumin

Joseph, K. S., Anguizola, J. & Hage, D. S., Jan 25 2011, In : Journal of Pharmaceutical and Biomedical Analysis. 54, 2, p. 426-432 7 p.

Research output: Contribution to journalArticle

Tolbutamide
Serum Albumin
Medical problems
Drug interactions
Affinity chromatography
52 Citations (Scopus)

Characterization of drug interactions with serum proteins by using high-performance affinity chromatography

Hage, D. S., Anguizola, J., Barnaby, O., Jackson, A., Yoo, M. J., Papastavros, E., Pfaunmiller, E., Sobansky, M. & Tong, Z., May 1 2011, In : Current Drug Metabolism. 12, 4, p. 313-328 16 p.

Research output: Contribution to journalArticle

Drug interactions
Affinity chromatography
Drug Interactions
Affinity Chromatography
Blood Proteins