David S Hage

  • 7838 Citations
  • 49 h-Index
1984 …2020
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Research Output 1984 2020

2020

Clinical and pharmaceutical applications of affinity ligands in capillary electrophoresis: A review

Zhang, C., Woolfork, A. G., Suh, K., Ovbude, S., Bi, C., Elzoeiry, M. & Hage, D. S., Jan 5 2020, In : Journal of Pharmaceutical and Biomedical Analysis. 177, 112882.

Research output: Contribution to journalReview article

Capillary electrophoresis
Capillary Electrophoresis
Ligands
Pharmaceutical Preparations
Immunoassay
Open Access
Affinity chromatography
Affinity Chromatography
Serum Albumin
Pharmaceutical Preparations
Proteins
2019
1 Citation (Scopus)

An overview of CE in clinical analysis

Hage, D. S., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 3-11 9 p. (Methods in Molecular Biology; vol. 1972).

Research output: Chapter in Book/Report/Conference proceedingChapter

Capillary Electrophoresis
Clinical Chemistry
Electrophoresis
Gels
2 Citations (Scopus)
Tolazamide
Affinity chromatography
Affinity Chromatography
Serum Albumin
Binding Sites
Glipizide
Affinity chromatography
Affinity Chromatography
Serum Albumin
Glucose

Development and evaluation of silica-based lectin microcolumns for glycoform analysis of alpha1-acid glycoprotein

Zhang, C. & Hage, D. S., Oct 31 2019, In : Analytica Chimica Acta. 1078, p. 189-199 11 p.

Research output: Contribution to journalArticle

Lectins
Silicon Dioxide
Glycoproteins
silica
Concanavalin A

Development of a microcolumn one-site immunometric assay for a protein biomarker: Analysis of alpha1-acid glycoprotein

Zhang, C., Lott, S., Clarke, W. & Hage, D. S., Jan 1 2019, (Accepted/In press) In : Journal of Chromatography A. 460558.

Research output: Contribution to journalArticle

Biomarkers
Assays
Glycoproteins
Acids
Proteins

Glycoform analysis of Alpha1-Acid glycoprotein by capillary electrophoresis using electrophoretic injection

Zhang, C., Clarke, W. & Hage, D. S., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 41-56 16 p. (Methods in Molecular Biology; vol. 1972).

Research output: Chapter in Book/Report/Conference proceedingChapter

Capillary Electrophoresis
Glycoproteins
Injections
Acids
Serum

Kinetic Analysis by Affinity Chromatography

Iftekhar, S., Ovbude, S. T. & Hage, D. S., Oct 18 2019, In : Frontiers in Chemistry. 7, 673.

Research output: Contribution to journalReview article

Open Access
Affinity chromatography
Rate constants
Kinetics
1 Citation (Scopus)
Glycogen
Silicon Dioxide
Serum Albumin
Immobilization
Proteins
5 Citations (Scopus)

Testosterone meets albumin-the molecular mechanism of sex hormone transport by serum albumins

Czub, M. P., Venkataramany, B. S., Majorek, K. A., Handing, K. B., Porebski, P. J., Beeram, S. R., Suh, K., Woolfork, A. G., Hage, D. S., Shabalin, I. G. & Minor, W., Jan 1 2019, In : Chemical Science. 10, 6, p. 1607-1618 12 p.

Research output: Contribution to journalArticle

Open Access
Gonadal Steroid Hormones
Serum Albumin
Testosterone
Albumins
Blood
2018

Affinity-Based Separation Methods for the Study of Biological Interactions

Hage, D. S., Aug 15 2018, In : Methods. 146, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Affinity chromatography
Biochemistry
1 Citation (Scopus)

Affinity extraction of emerging contaminants from water based on bovine serum albumin as a binding agent

Papastavros, E., Remmers, R. A., Snow, D. D., Cassada, D. A. & Hage, D. S., Mar 2018, In : Journal of Separation Science. 41, 5, p. 1074-1082 9 p.

Research output: Contribution to journalArticle

Bovine Serum Albumin
Sorbents
Impurities
Liquid chromatography
Water
5 Citations (Scopus)

Analysis of solute-protein interactions and solute-solute competition by zonal elution affinity chromatography

Tao, P., Poddar, S., Sun, Z., Hage, D. S. & Chen, J., Aug 15 2018, In : Methods. 146, p. 3-11 9 p.

Research output: Contribution to journalReview article

Affinity chromatography
Affinity Chromatography
Protein Binding
Proteins
Biological Phenomena
1 Citation (Scopus)
Serum Albumin
Pharmaceutical Preparations
glimepiride
Rate constants
Glipizide
4 Citations (Scopus)

Characterization of solution-phase drug-protein interactions by ultrafast affinity extraction

Beeram, S. R., Zheng, X., Suh, K. & Hage, D. S., Aug 15 2018, In : Methods. 146, p. 46-57 12 p.

Research output: Contribution to journalArticle

Drug Interactions
Pharmaceutical Preparations
Rate constants
Proteins
Serum Albumin
3 Citations (Scopus)
Chlorpropamide
Serum Albumin
Medical problems
Pharmaceutical Preparations
Binding Sites
2 Citations (Scopus)
Immunochromatography
Dengue Virus
Dengue
Immunoassay
Serum
17 Citations (Scopus)

High performance affinity chromatography and related separation methods for the analysis of biological and pharmaceutical agents

Zhang, C., Rodriguez, E., Bi, C., Zheng, X., Suresh, D., Suh, K., Li, Z., Elsebaei, F. & Hage, D. S., Jan 21 2018, In : Analyst. 143, 2, p. 374-391 18 p.

Research output: Contribution to journalReview article

Affinity chromatography
Biological Factors
Affinity Chromatography
Drug products
chromatography
6 Citations (Scopus)

Peak decay analysis and biointeraction studies of immunoglobulin binding and dissociation on protein G affinity microcolumns

Anguizola, J. A., Pfaunmiller, E. L., Milanuk, M. L. & Hage, D. S., Aug 15 2018, In : Methods. 146, p. 39-45 7 p.

Research output: Contribution to journalArticle

Immunoglobulins
Immunoglobulin G
Regeneration
Proteins
Immobilized Proteins
5 Citations (Scopus)
piperine
Curcumin
Epithelial Cells
Proteins
Inflammation
2017
2 Citations (Scopus)

Affinity chromatography

Hage, D. S., Anguizola, J. A., Li, R., Matsuda, R., Papastavros, E., Pfaunmiller, E., Sobansky, M. & Zheng, X., Jun 21 2017, Liquid Chromatography: Fundamentals and Instrumentation: Second Edition. Elsevier, Vol. 1. p. 319-341 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

chromatography
affinity
ligands
elution
biomimetics
11 Citations (Scopus)

Affinity monolith chromatography: A review of general principles and applications

Li, Z., Rodriguez, E., Azaria, S., Pekarek, A. & Hage, D. S., Nov 2017, In : ELECTROPHORESIS. 38, 22-23, p. 2837-2850 14 p.

Research output: Contribution to journalReview article

Affinity chromatography
Affinity Chromatography
Chromatography
Cryogels
Ion chromatography
10 Citations (Scopus)

Analysis of biological interactions by affinity chromatography: Clinical and pharmaceutical applications

Hage, D. S., Jun 2017, In : Clinical Chemistry. 63, 6, p. 1083-1093 11 p.

Research output: Contribution to journalReview article

Affinity chromatography
Affinity Chromatography
Pharmaceutical Preparations
Precision Medicine
Preclinical Drug Evaluations
9 Citations (Scopus)
Drug interactions
Affinity chromatography
Drug Interactions
Affinity Chromatography
Blood Proteins
7 Citations (Scopus)

Chromatographic studies of drug interactions with alpha1-acid glycoprotein by ultrafast affinity extraction and peak profiling

Beeram, S., Bi, C., Zheng, X. & Hage, D. S., May 12 2017, In : Journal of Chromatography A. 1497, p. 92-101 10 p.

Research output: Contribution to journalArticle

Drug interactions
Drug Interactions
Glycoproteins
Acids
Pharmaceutical Preparations
25 Citations (Scopus)

Dual-target binding ligands with modulated pharmacokinetics for endoradiotherapy of prostate cancer

Kelly, J. M., Amor-Coarasa, A., Nikolopoulou, A., Wüstemann, T., Barelli, P., Kim, D., Williams, C., Zheng, X., Bi, C., Hu, B., Warren, J. D., Hage, D. S., Di Magno, S. G. & Babich, J. W., Sep 1 2017, In : Journal of Nuclear Medicine. 58, 9, p. 1442-1449 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Pharmacokinetics
Ligands
Serum Albumin
Kidney
7 Citations (Scopus)

Glycoform analysis of alpha1-acid glycoprotein based on capillary electrophoresis and electrophoretic injection

Zhang, C., Bi, C., Clarke, W. & Hage, D. S., Nov 10 2017, In : Journal of Chromatography A. 1523, p. 114-122 9 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Capillary Electrophoresis
Glycoproteins
Salt removal
Injections
5 Citations (Scopus)

Nanomaterials as stationary phases and supports in liquid chromatography

Beeram, S. R., Rodriguez, E., Doddavenkatanna, S., Li, Z., Pekarek, A., Peev, D., Goerl, K., Trovato, G., Hofmann, T. & Hage, D. S., Oct 2017, In : ELECTROPHORESIS. 38, 19, p. 2498-2512 15 p.

Research output: Contribution to journalReview article

Nanostructures
Liquid chromatography
Nanostructured materials
Liquid Chromatography
Chromatography
5 Citations (Scopus)

Studies of drug interactions with alpha1-acid glycoprotein by using on-line immunoextraction and high-performance affinity chromatography

Bi, C., Matsuda, R., Zhang, C., Isingizwe, Z., Clarke, W. & Hage, D. S., Oct 13 2017, In : Journal of Chromatography A. 1519, p. 64-73 10 p.

Research output: Contribution to journalArticle

Drug interactions
Affinity chromatography
Drug Interactions
Affinity Chromatography
Glycoproteins
2016
7 Citations (Scopus)

Analysis of free drug fractions in human serum by ultrafast affinity extraction and two-dimensional affinity chromatography

Zheng, X., Podariu, M., Matsuda, R. & Hage, D. S., Jan 1 2016, In : Analytical and Bioanalytical Chemistry. 408, 1, p. 131-140 10 p.

Research output: Contribution to journalArticle

Affinity chromatography
Affinity Chromatography
Serum Albumin
Serum
Pharmaceutical Preparations
8 Citations (Scopus)
Affinity chromatography
Affinity Chromatography
Glycoproteins
Acids
Serum
7 Citations (Scopus)

Anisotropic contrast optical microscope

Peev, D., Hofmann, T., Kananizadeh, N., Beeram, S., Rodriguez, E., Wimer, S., Rodenhausen, K. B., Herzinger, C. M., Kasputis, T., Pfaunmiller, E., Nguyen, A., Korlacki, R., Pannier, A. K., Li, Y., Schubert, E., Hage, D. S. & Schubert, M., Nov 1 2016, In : Review of Scientific Instruments. 87, 11, 113701.

Research output: Contribution to journalArticle

optical microscopes
Microscopes
Ellipsometry
filters
Polarization
6 Citations (Scopus)
Chromatographic analysis
Serum Albumin
Chromatography
Fatty Acids
Tryptophan
12 Citations (Scopus)

Chromatographic studies of protein-based chiral separations

Bi, C., Zheng, X., Azaria, S., Beeram, S., Li, Z. & Hage, D. S., Sep 2016, In : Separations. 3, 3, 27.

Research output: Contribution to journalReview article

Open Access
Proteins
Cellulose 1,4-beta-Cellobiosidase
Ovomucin
Penicillin Amidase
Glycoproteins
14 Citations (Scopus)

Entrapment of alpha1-acid glycoprotein in high-performance affinity columns for drug-protein binding studies

Bi, C., Jackson, A., Vargas-Badilla, J., Li, R., Rada, G., Anguizola, J., Pfaunmiller, E. & Hage, D. S., May 15 2016, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1021, p. 188-196 9 p.

Research output: Contribution to journalArticle

Protein Binding
Glycoproteins
Acids
Pharmaceutical Preparations
Equilibrium constants
9 Citations (Scopus)

Glycoform analysis of alpha1-acid glycoprotein by capillary electrophoresis

Zhang, C. & Hage, D. S., Dec 2 2016, In : Journal of Chromatography A. 1475, p. 102-109 8 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Capillary Electrophoresis
Glycoproteins
Acids
Electroosmosis
8 Citations (Scopus)

High-Performance Affinity Chromatography: Applications in Drug-Protein Binding Studies and Personalized Medicine

Li, Z., Beeram, S. R., Bi, C., Suresh, D., Zheng, X. & Hage, D. S., Jan 1 2016, Advances in Protein Chemistry and Structural Biology. Donev, R. (ed.). Academic Press Inc., p. 1-39 39 p. (Advances in Protein Chemistry and Structural Biology; vol. 102).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Affinity chromatography
Precision Medicine
Affinity Chromatography
Protein Binding
Medicine

Liquid Chromatography

Li, Z., Beeram, S., Bi, C., Kaufmann, E., Matsuda, R., Podariu, M., Rodriguez, E., Zheng, X. & Hage, D. S., Jan 1 2016, Handbook of Measurement in Science and Engineering. wiley, Vol. 3. p. 2409-2429 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Industrial engineering
Liquid chromatography
9 Citations (Scopus)

On-column entrapment of alpha1-acid glycoprotein for studies of drug-protein binding by high-performance affinity chromatography

Anguizola, J., Bi, C., Koke, M., Jackson, A. & Hage, D. S., Aug 1 2016, In : Analytical and Bioanalytical Chemistry. 408, 21, p. 5745-5756 12 p.

Research output: Contribution to journalArticle

Affinity chromatography
Affinity Chromatography
Protein Binding
Glycoproteins
Acids

Optimizing sequence coverage for a moderate mass protein in nano-electrospray ionization quadrupole time-of-flight mass spectrometry

Matsuda, R., Kolli, V., Woods, M., Dodds, E. D. & Hage, D. S., Sep 15 2016, In : Analytical Biochemistry. 509, p. 115-117 3 p.

Research output: Contribution to journalArticle

Electrospray ionization
Mass spectrometry
Mass Spectrometry
Peptides
Proteins
4 Citations (Scopus)

Use of protein G microcolumns in chromatographic immunoassays: A comparison of competitive binding formats

Pfaunmiller, E. L., Anguizola, J. A., Milanuk, M. L., Carter, N. T. & Hage, D. S., May 15 2016, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1021, p. 91-100 10 p.

Research output: Contribution to journalArticle

Competitive Binding
Immunoassay
Serum Albumin
Limit of Detection
Injections
2015
Liquid chromatography
Pharmaceutical Preparations
Pharmacokinetics
Chromatography
Metabolism
11 Citations (Scopus)

Affinity chromatography: A historical perspective

Hage, D. S. & Matsuda, R., Jan 1 2015, In : Methods in Molecular Biology. 1286

Research output: Contribution to journalArticle

Affinity Chromatography
Complex Mixtures
Liquid Chromatography
Immobilization
9 Citations (Scopus)

Analysis of drug-protein binding using on-line immunoextraction and high-performance affinity microcolumns: Studies with normal and glycated human serum albumin

Matsuda, R., Jobe, D., Beyersdorf, J. & Hage, D. S., Oct 16 2015, In : Journal of Chromatography A. 1416, p. 112-120 9 p.

Research output: Contribution to journalArticle

Protein Binding
Serum Albumin
Pharmaceutical Preparations
Affinity chromatography
Proteins
10 Citations (Scopus)
Drug Interactions
Affinity Chromatography
Serum Albumin
Proteins
Liquid Chromatography
12 Citations (Scopus)

Analysis of glipizide binding to normal and glycated human serum albumin by high-performance affinity chromatography

Matsuda, R., Li, Z., Zheng, X. & Hage, D. S., Jul 28 2015, In : Analytical and Bioanalytical Chemistry. 407, 18, p. 5309-5321 13 p., 8688.

Research output: Contribution to journalArticle

Glipizide
Affinity chromatography
Affinity Chromatography
Serum Albumin
Pharmaceutical Preparations