David C McMillan, PhD

Professor

  • 806 Citations
  • 20 h-Index
1985 …2011
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Research Output 1985 2011

  • 806 Citations
  • 20 h-Index
  • 33 Article
  • 2 Review article
2011
1 Citation (Scopus)

Web-based course in neuroimmune pharmacology

McMillan, D. C., Mar 1 2011, In : Journal of Neuroimmune Pharmacology. 6, 1, p. 76-79 4 p.

Research output: Contribution to journalReview article

Distance Education
Learning
Pharmacology
Students
Curriculum
2009
26 Citations (Scopus)

Trichloroethylene risk assessment: A review and commentary

Jollow, D. J., Bruckner, J. V., McMillan, D. C., Fisher, J. W., Hoel, D. G. & Mohr, L. C., Nov 12 2009, In : Critical reviews in toxicology. 39, 9, p. 782-797 16 p.

Research output: Contribution to journalReview article

Trichloroethylene
Risk assessment
Pharmacokinetics
Dichloroacetic Acid
Drinking Water
2006
19 Citations (Scopus)

Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: Relative disposition of chloral hydrate to trichloroacetate and trichloroethanol

Bronley-DeLancey, A., McMillan, D. C., McMillan, J. E. M., Jollow, D. J., Mohr, L. C. & Hoel, D. G., Aug 1 2006, In : Environmental Health Perspectives. 114, 8, p. 1237-1242 6 p.

Research output: Contribution to journalArticle

Chloral Hydrate
Trichloroethylene
aldehyde
Aldehyde Dehydrogenase
trichloroethylene
16 Citations (Scopus)
S-Adenosylmethionine
Galactosamine
Cytotoxicity
Cell culture
Glutathione
2005
30 Citations (Scopus)

Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents

McMillan, D. C., Powell, C. L., Bowman, Z. S., Morrow, J. D. & Jollow, D. J., Nov 1 2005, In : Toxicological Sciences. 88, 1, p. 274-283 10 p.

Research output: Contribution to journalArticle

Hemolytic Agents
Phosphatidylserines
Lipid Peroxidation
Reactive Oxygen Species
Macrophages
26 Citations (Scopus)
Primaquine
Cytoskeletal Proteins
Hemolytic Anemia
Membrane Lipids
Lipid Peroxidation
22 Citations (Scopus)
Primaquine
Hemolytic Anemia
Erythrocytes
Macrophages
Radioactivity
2004
56 Citations (Scopus)

Primaquine-Induced Hemolytic Anemia: Susceptibility of Normal versus Glutathione-Depleted Rat Erythrocytes to 5-Hydroxyprimaquine

Bowman, Z. S., Oatis, J. E., Whelan, J. L., Jollow, D. J. & McMillan, D. C., Apr 1 2004, In : Journal of Pharmacology and Experimental Therapeutics. 309, 1, p. 79-85 7 p.

Research output: Contribution to journalArticle

Primaquine
Hemolytic Anemia
Glutathione
Erythrocytes
diethyl maleate
45 Citations (Scopus)

Role of oxidant stress in Lawsone-induced hemolytic anemia

McMillan, D. C., Sarvete, S. D., Oatis, J. E. & Jollow, D. J., Dec 1 2004, In : Toxicological Sciences. 82, 2, p. 647-655 9 p.

Research output: Contribution to journalArticle

Hemolytic Anemia
Oxidants
Hemolytic Agents
Erythrocytes
Oxidation-Reduction
2002
26 Citations (Scopus)
Primaquine
Cytoskeletal Proteins
Hemolytic Anemia
Membrane Lipids
Erythrocytes
18 Citations (Scopus)

Primaquine-induced hemolytic anemia: Formation of free radicals in rat erythrocytes exposed to 6-methoxy-8-hydroxylaminoquinoline

Bolchoz, L. J. C., Gelasco, A. K., Jollow, D. J. & McMillan, D. C., Dec 1 2002, In : Journal of Pharmacology and Experimental Therapeutics. 303, 3, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

Primaquine
Hemolytic Anemia
Free Radicals
Erythrocytes
Hemolytic Agents
2001
27 Citations (Scopus)

Favism: Effect of divicine on rat erythrocyte sulfhydryl status, hexose monophosphate shunt activity, morphology, and membrane skeletal proteins

McMillan, D. C., Bolchoz, L. J. C. & Jollow, D. J., Aug 15 2001, In : Toxicological Sciences. 62, 2, p. 353-359 7 p.

Research output: Contribution to journalArticle

Favism
Pentose Phosphate Pathway
Hexoses
Rats
Membrane Proteins
28 Citations (Scopus)

Oxidative stress, glucose-6-phosphate dehydrogenase and the red cell

Jollow, D. J. & McMillan, D. C., Dec 1 2001, In : Advances in experimental medicine and biology. 500, p. 595-605 11 p.

Research output: Contribution to journalArticle

Oxidative stress
Glucosephosphate Dehydrogenase
Oxidative Stress
Cells
Lipids
47 Citations (Scopus)

Primaquine-induced hemolytic anemia: Formation and hemotoxicity of the arylhydroxylamine metabolite 6-methoxy-8-hydroxylaminoquinoline

Bolchoz, L. J. C., Budinsky, R. A., Mcmillan, D. C. & Jollow, D. J., May 8 2001, In : Journal of Pharmacology and Experimental Therapeutics. 297, 2, p. 509-515 7 p.

Research output: Contribution to journalArticle

Primaquine
Hemolytic Anemia
Erythrocytes
Liver Microsomes
Erythrocyte Aging
1999
9 Citations (Scopus)

Favism: Divicine hemotoxicity in the rat

McMillan, D. C. & Jollow, D. J., Nov 3 1999, In : Toxicological Sciences. 51, 2, p. 310-316 7 p.

Research output: Contribution to journalArticle

Favism
Rats
Glucosephosphate Dehydrogenase
Vicia faba
Blood
1998
24 Citations (Scopus)

Role of lipid peroxidation in dapsone-lnduced hemolytic anemia

McMillan, D. C., Jensen, C. B. & Jollow, D. J., Dec 1 1998, In : Journal of Pharmacology and Experimental Therapeutics. 287, 3, p. 868-876 9 p.

Research output: Contribution to journalArticle

Dapsone
Hemolytic Anemia
Lipid Peroxidation
Thiobarbituric Acid Reactive Substances
Hemolytic Agents
1997
11 Citations (Scopus)

Detection of trichloroethylene-protein adducts in rat liver and plasma

Halmes, N. C., Perkins, E. J., McMillan, D. C. & Pumford, N. R., Aug 22 1997, In : Toxicology Letters. 92, 3, p. 187-194 8 p.

Research output: Contribution to journalArticle

Trichloroethylene
Liver
Rats
Plasmas
Proteins
25 Citations (Scopus)

Formation of free radicals and protein mixed disulfides in rat red cells exposed to dapsone hydroxylamine

Bradshaw, T. P., McMillan, D. C., Crouch, R. K. & Jollow, D. J., May 3 1997, In : Free Radical Biology and Medicine. 22, 7, p. 1183-1193 11 p.

Research output: Contribution to journalArticle

Disulfides
Free Radicals
Rats
Cells
Proteins
1996
48 Citations (Scopus)

Immunochemical detection of protein adducts in mice treated with trichloroethylene

Halmes, N. C., McMillan, D. C., Oatis, J. E. & Pumford, N. R., Mar 1 1996, In : Chemical Research in Toxicology. 9, 2, p. 451-456 6 p.

Research output: Contribution to journalArticle

Trichloroethylene
Proteins
Antibodies
Cytochrome P-450 CYP2E1
Metabolites
1995
46 Citations (Scopus)

Dapsone-induced hemolytic anemia

Jollow, D. J., Bradshaw, T. P. & Mcmillan, D. C., Jan 1 1995, In : Drug Metabolism Reviews. 27, 1-2, p. 107-124 18 p.

Research output: Contribution to journalArticle

Dapsone
Hemolytic Anemia
Erythrocytes
Hemodynamics
19 Citations (Scopus)
Dapsone
Hemolytic Anemia
Membrane Proteins
Erythrocytes
Glutathione Disulfide
26 Citations (Scopus)

Identification of free radicals produced in rat erythrocytes exposed to hemolytic concentrations of phenylhydroxylamine

Bradshaw, T. P., McMillan, D. C., Crouch, R. K. & Jollow, D. J., Feb 1995, In : Free Radical Biology and Medicine. 18, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

Free Radicals
Rats
Erythrocytes
Oxides
Cells
1993
11 Citations (Scopus)

Chemical Analysis and Hemolytic Activity of the Fava Bean Aglycon Divicine

McMillan, D. C., Schey, K. L., Meier, G. P. & Jollow, D. J., Jan 1 1993, In : Chemical Research in Toxicology. 6, 4, p. 439-444 6 p.

Research output: Contribution to journalArticle

Vicia faba
Chemical analysis
Erythrocyte Aging
Glucosides
Rats
1991
1 Citation (Scopus)

Arylamine-induced hemolytic anemia: Electron spin resonance spectrometry studies

Bradshaw, T. P., McMillan, D. C., Crouch, R. K. & Jollow, D. J., Oct 7 1991, In : Advances in experimental medicine and biology. 283, p. 253-255 3 p.

Research output: Contribution to journalArticle

Cyclic N-Oxides
Hydroxylamines
Electron spin resonance spectroscopy
Spin Labels
Spectrometry
5 Citations (Scopus)

Contribution of 3,4-dichlorophenylhydroxylamine in prop anil-induced hemolytic anemia

McMillan, D. C., Bradshaw, T. P., McMillan, J. M., Hinson, J. A. & Jollow, D. J., Oct 7 1991, In : Advances in experimental medicine and biology. 283, p. 343-345 3 p.

Research output: Contribution to journalArticle

Propanil
Aniline Compounds
Hydroxylamines
Inbred Strains Rats
Hemolytic Anemia
38 Citations (Scopus)

Role of metabolites in propanil-induced hemolytic anemia

McMillan, D. C., Bradshaw, T. P., Hinson, J. A. & Jollow, D. J., Aug 1991, In : Toxicology and Applied Pharmacology. 110, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

Propanil
Hemolytic Anemia
Metabolites
Erythrocyte Aging
Methemoglobinemia
1990
43 Citations (Scopus)

Metabolism of the arylamide herbicide propanil. I. Microsomal metabolism and in vitro methemoglobinemia

McMillan, D. C., Freeman, J. P. & Hinson, J. A., Mar 15 1990, In : Toxicology and Applied Pharmacology. 103, 1, p. 90-101 12 p.

Research output: Contribution to journalArticle

Methemoglobinemia
Herbicides
Metabolism
Metabolites
amidase
22 Citations (Scopus)

Metabolism of the arylamide herbicide propanil. II. Effects of propanil and its derivatives on hepatic microsomal drug-metabolizing enzymes in the rat

McMillan, D. C., Leakey, J. E. A., Arlotto, M. P., McMillan, J. E. M. & Hinson, J. A., Mar 15 1990, In : Toxicology and Applied Pharmacology. 103, 1, p. 102-112 11 p.

Research output: Contribution to journalArticle

Propanil
Herbicides
Metabolism
Rats
Derivatives
26 Citations (Scopus)

Propanil-induced methemoglobinemia and hemoglobin binding in the rat

McMillan, D. C., McRae, T. A. & Hinson, J. A., Sep 15 1990, In : Toxicology and Applied Pharmacology. 105, 3, p. 503-507 5 p.

Research output: Contribution to journalArticle

Propanil
Methemoglobinemia
Rats
Hemoglobins
Methemoglobin
1989
20 Citations (Scopus)

Pretreatment with mixed‐function oxidase inducers increases the sensitivity of the hepatocyte/DNA repair assay

Shaddock, J. G., Heflich, R. H., McMillan, D. C., Hinson, J. A. & Casciano, D. A., 1989, In : Environmental and Molecular Mutagenesis. 13, 4, p. 281-288 8 p.

Research output: Contribution to journalArticle

DNA Repair
Hepatocytes
Oxidoreductases
Carcinogens
Chlorodiphenyl (54% Chlorine)
1988
13 Citations (Scopus)
Propanil
Salmonella
Hypoxanthine
Guanine
Salmonella typhimurium
Propanil
Salmonella
Hypoxanthine
Guanine
Salmonella typhimurium
9 Citations (Scopus)

Microbial metabolism and detoxification of 7,12-dimethylbenz[a]anthracene

McMillan, D. C., Fu, P. P., Freeman, J. P., Miller, D. W. & Cerniglia, C. E., Jun 1 1988, In : Journal of Industrial Microbiology. 3, 4, p. 211-225 15 p.

Research output: Contribution to journalArticle

9,10-Dimethyl-1,2-benzanthracene
Detoxification
Anthracene
Metabolites
Metabolism
1987
14 Citations (Scopus)
liquid chromatography
metabolite
metabolism
Syncephalastrum racemosum
Cunninghamella elegans
1985
9 Citations (Scopus)

Fungal metabolism of tert-butylphenyl diphenyl phosphate

Heitkamp, M. A., Freeman, J. P., McMillan, D. C. & Cerniglia, C. E., Jan 1 1985, In : Applied and environmental microbiology. 50, 2, p. 265-273 9 p.

Research output: Contribution to journalArticle

Cyclic Hydrocarbons
Mucorales
Organophosphorus Compounds
Organophosphates
organophosphate