Colin D Meiklejohn, PhD

Assistant Professor

  • 1928 Citations
  • 17 h-Index
20012019
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Research Output 2001 2019

  • 1928 Citations
  • 17 h-Index
  • 19 Article
  • 2 Comment/debate
  • 2 Short survey
  • 2 Review article
2019
2 Citations (Scopus)

Temperature-Sensitive Reproduction and the Physiological and Evolutionary Potential for Mother's Curse

Montooth, K. L., Dhawanjewar, A. S. & Meiklejohn, C. D., Oct 1 2019, In : Integrative and Comparative Biology. 59, 4, p. 890-899 10 p.

Research output: Contribution to journalArticle

Open Access
gender
mutation
male fertility
temperature
Drosophila
2018
3 Citations (Scopus)

Gene flow mediates the role of sex chromosome meiotic drive during complex speciation

Meiklejohn, C. D., Landeen, E. L., Gordon, K. E., Rzatkiewicz, T., Kingan, S. B., Geneva, A. J., Vedanayagam, J. P., Muirhead, C. A., Garrigan, D., Stern, D. L. & Presgraves, D. C., Dec 1 2018, In : eLife. 7, e35468.

Research output: Contribution to journalArticle

Sex Chromosomes
Gene Flow
Genes
Metagenomics
Male Infertility

Invasion of the P elements: Tolerance is not futile

Meiklejohn, C. D. & Blumenstiel, J. P., Oct 1 2018, In : PLoS biology. 16, 10, p. e3000036

Research output: Contribution to journalComment/debate

transposons
Parasites
Parasite Load
parasites
parasite load
6 Citations (Scopus)

Mitochondrial dysfunction and infection generate immunity–Fecundity tradeoffs in Drosophila

Buchanan, J. L., Meiklejohn, C. D. & Montooth, K. L., Jan 1 2018, In : Integrative and Comparative Biology. 58, 3, p. 591-603 13 p.

Research output: Contribution to journalArticle

Drosophila
nutrients
genotype
infection
energy metabolism

RNAi Doxxes Segregation Distorters on the X

Blumenstiel, J. P. & Meiklejohn, C. D., Aug 6 2018, In : Developmental cell. 46, 3, p. 251-253 3 p.

Research output: Contribution to journalShort survey

RNA Interference
RNA
Chromosome Segregation
Sex Chromosomes
Genes
2016
1 Citation (Scopus)

Heterochromatin and genetic conflict

Meiklejohn, C. D., Apr 12 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 15, p. 3915-3917 3 p.

Research output: Contribution to journalComment/debate

16 Citations (Scopus)

Sex Chromosome-wide Transcriptional Suppression and Compensatory Cis-Regulatory Evolution Mediate Gene Expression in the Drosophila Male Germline

Landeen, E. L., Muirhead, C. A., Wright, L., Meiklejohn, C. D. & Presgraves, D. C., Jul 12 2016, In : PLoS biology. 14, 7, e1002499.

Research output: Contribution to journalArticle

Sex Chromosomes
sex chromosomes
Gene expression
Drosophila
germ cells
2014
9 Citations (Scopus)

Genome-Wide gene expression effects of sex chromosome imprinting in drosophila

Lemos, B., Branco, A. T., Jiang, P. P., Hartl, D. L. & Meiklejohn, C. D., Jan 2014, In : G3: Genes, Genomes, Genetics. 4, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Sex Chromosomes
Drosophila
Y Chromosome
Genome
Gene Expression
28 Citations (Scopus)

The roles of cis- and trans-regulation in the evolution of regulatory incompatibilities and sexually dimorphic gene expression

Meiklejohn, C. D., Coolon, J. D., Hartl, D. L. & Wittkopp, P. J., Jan 1 2014, In : Genome Research. 24, 1, p. 84-95 12 p.

Research output: Contribution to journalArticle

Gene Expression
Alleles
Molecular Evolution
Heterozygote
Sex Characteristics
2013
110 Citations (Scopus)

An Incompatibility between a Mitochondrial tRNA and Its Nuclear-Encoded tRNA Synthetase Compromises Development and Fitness in Drosophila

Meiklejohn, C. D., Holmbeck, M. A., Siddiq, M. A., Abt, D. N., Rand, D. M. & Montooth, K. L., Jan 1 2013, In : PLoS genetics. 9, 1, e1003238.

Research output: Contribution to journalArticle

nuclear-cytoplasmic interactions
Amino Acyl-tRNA Synthetases
incompatibility
Transfer RNA
ligases
2012
40 Citations (Scopus)

Little evidence for demasculinization of the Drosophila X chromosome among genes expressed in the male germline

Meiklejohn, C. D. & Presgraves, D. C., Dec 1 2012, In : Genome Biology and Evolution. 4, 10, p. 1007-1016 10 p.

Research output: Contribution to journalArticle

X-Linked Genes
X chromosome
Drosophila
Testis
chromosome
2011
76 Citations (Scopus)

Sex chromosome-specific regulation in the drosophila male germline but little evidence for chromosomal dosage compensation or meiotic inactivation

Meiklejohn, C. D., Landeen, E. L., Cook, J. M., Kingan, S. B. & Presgraves, D. C., Aug 1 2011, In : PLoS biology. 9, 8, e1001126.

Research output: Contribution to journalArticle

Sex Chromosomes
sex chromosomes
X chromosome
Chromosomes
Drosophila
2010
76 Citations (Scopus)

Genetic conflict and sex chromosome evolution

Meiklejohn, C. D. & Tao, Y., Apr 1 2010, In : Trends in Ecology and Evolution. 25, 4, p. 215-223 9 p.

Research output: Contribution to journalArticle

sex chromosomes
chromosome
chromosome transmission
genome
sex determination
64 Citations (Scopus)

Mitochondrial-nuclear epistasis affects fitness within species but does not contribute to fixed incompatibilities between species of Drosophila

Montooth, K. L., Meiklejohn, C. D., Abt, D. N. & Rand, D. M., Dec 1 2010, In : Evolution. 64, 12, p. 3364-3379 16 p.

Research output: Contribution to journalArticle

epistasis
incompatibility
Drosophila melanogaster
Drosophila
fitness
2007
196 Citations (Scopus)

Positive and negative selection on the mitochondrial genome

Meiklejohn, C. D., Montooth, K. L. & Rand, D. M., Jun 1 2007, In : Trends in Genetics. 23, 6, p. 259-263 5 p.

Research output: Contribution to journalShort survey

Mitochondrial Genome
Mitochondrial DNA
Genetic Drift
Mitochondrial Genes
Molecular Evolution
2005
18 Citations (Scopus)

A Bayesian method for analysing spotted microarray data

Meiklejohn, C. D. & Townsend, J. P., Dec 1 2005, In : Briefings in bioinformatics. 6, 4, p. 318-330 13 p.

Research output: Contribution to journalReview article

Bayes Theorem
Microarrays
Gene expression
Gene Expression
Patents and inventions
182 Citations (Scopus)
protein-protein interactions
Gene expression
Drosophila
gene expression
protein synthesis
107 Citations (Scopus)

Rates of divergence in gene expression profiles of primates, mice, and flies: Stabilizing selection and variability among functional categories

Lemos, B., Meiklejohn, C. D., Cáceres, M. & Hartl, D. L., Jan 2005, In : Evolution. 59, 1, p. 126-137 12 p.

Research output: Contribution to journalArticle

Open Access
Transcriptome
Diptera
primate
Primates
Drosophila
2004
39 Citations (Scopus)

Identification of a locus under complex positive selection in Drosophila simulans by haplotype mapping and composite-likelihood estimation

Meiklejohn, C. D., Kim, Y., Hartl, D. L. & Parsch, J., Sep 1 2004, In : Genetics. 168, 1, p. 265-279 15 p.

Research output: Contribution to journalArticle

Haplotypes
Genetic Recombination
Alleles
Linkage Disequilibrium
Testis
44 Citations (Scopus)

Regulatory evolution across the protein interaction network

Lemos, B., Meiklejohn, C. D. & Hartl, D. L., Oct 1 2004, In : Nature Genetics. 36, 10, p. 1059-1060 2 p.

Research output: Contribution to journalArticle

Protein Interaction Maps
Proteins
Saccharomycetales
Diptera
Fruit
2003
218 Citations (Scopus)

Rapid evolution of male-biased gene expression in Drosophila

Meiklejohn, C. D., Parsch, J., Ranz, J. M. & Hartl, D. L., Aug 19 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 17, p. 9894-9899 6 p.

Research output: Contribution to journalArticle

Drosophila
Gene Expression
Genes
Genetic Selection
Oligonucleotide Array Sequence Analysis
453 Citations (Scopus)

Sex-dependent gene expression and evolution of the Drosophila transcriptome

Ranz, J. M., Castillo-Davis, C. I., Meiklejohn, C. D. & Hartl, D. L., Jun 13 2003, In : Science. 300, 5626, p. 1742-1745 4 p.

Research output: Contribution to journalArticle

Transcriptome
Drosophila
Gene Expression
Genes
Sex Preselection
2002
169 Citations (Scopus)

A single mode of canalization

Meiklejohn, C. D. & Hartl, D. L., Oct 1 2002, In : Trends in Ecology and Evolution. 17, 10, p. 468-473 6 p.

Research output: Contribution to journalReview article

buffering
phenotype
phenotypic variation
biological processes
fixation
2001
34 Citations (Scopus)

Molecular evolution of the ocnus and janus genes in the Drosophila melanogaster species subgroup

Parsch, J., Meiklejohn, C. D., Hauschteck-Jungen, E., Hunziker, P. & Hartl, D. L., Jan 1 2001, In : Molecular biology and evolution. 18, 5, p. 801-811 11 p.

Research output: Contribution to journalArticle

Open Access
Janus
Molecular Evolution
Drosophila melanogaster
Genes
gene
37 Citations (Scopus)

Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans

Parsch, J., Meiklejohn, C. D. & Haitl, D. L., Nov 17 2001, In : Genetics. 159, 2, p. 647-657 11 p.

Research output: Contribution to journalArticle

Alleles
Haplotypes
Genes
Genetic Selection
Linkage Disequilibrium