Benson J Edagwa, PhD

Assistant Professor

  • 434 Citations
  • 14 h-Index
20092019
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  • 4 Similar Profiles
Prodrugs Medicine & Life Sciences
Macrophages Engineering & Materials Science
Pharmaceutical Preparations Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
Pharmacokinetics Engineering & Materials Science
Rilpivirine Medicine & Life Sciences
Folic Acid Medicine & Life Sciences
Therapeutics Medicine & Life Sciences

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Research Output 2009 2019

  • 434 Citations
  • 14 h-Index
  • 32 Article
  • 2 Review article
  • 1 Chapter
  • 1 Short survey

A long acting nanoformulated lamivudine ProTide

Smith, N., Bade, A. N., Soni, D., Gautam, N., Alnouti, Y., Herskovitz, J., Ibrahim, I. M., Wojtkiewicz, M. S., Dyavar Shetty, B. L., McMillan, J. E., Gendelman, H. E. & Edagwa, B., Dec 2019, In : Biomaterials. 223, 119476.

Research output: Contribution to journalArticle

Pharmacokinetics
Lamivudine
Macrophages
T-cells
Metabolites

Creation of a long-acting rilpivirine prodrug nanoformulation

Hilaire, J. R., Bade, A. N., Sillman, B., Gautam, N., Herskovitz, J., Dyavar Shetty, B. L., Wojtkiewicz, M. S., Szlachetka, A., Lamberty, B. G., Sravanam, S., Fox, H. S., Alnouti, Y., Dash, P. K., McMillan, J. E. M., Edagwa, B. J. & Gendelman, H. E., Oct 2019, In : Journal of Controlled Release. 311-312, p. 201-211 11 p.

Research output: Contribution to journalArticle

Rilpivirine
Prodrugs
Pharmaceutical Preparations
Half-Life
Therapeutics
2 Citations (Scopus)

Nanoformulated Antiretroviral Therapy Attenuates Brain Metabolic Oxidative Stress

Montenegro-Burke, J. R., Woldstad, C. J., Fang, M., Bade, A. N., McMillan, J. M., Edagwa, B. J., Boska, M. D., Gendelman, H. E. & Siuzdak, G., Apr 1 2019, In : Molecular Neurobiology. 56, 4, p. 2896-2907 12 p.

Research output: Contribution to journalArticle

Oxidative Stress
Brain
Homeostasis
HIV Integrase Inhibitors
Central Nervous System
2 Citations (Scopus)

Pharmacokinetic testing of a first-generation cabotegravir prodrug in rhesus macaques

McMillan, J., Szlachetka, A., Zhou, T., Morsey, B., Lamberty, B., Callen, S., Gautam, N., Alnouti, Y., Edagwa, B., Gendelman, H. E. & Fox, H. S., Mar 1 2019, In : AIDS. 33, 3, p. 585-588 4 p.

Research output: Contribution to journalArticle

Prodrugs
Macaca mulatta
Pharmacokinetics
Poloxamer
HIV Infections

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

Dash, P. K., Kaminski, R., Bella, R., Su, H., Mathews, S., Ahooyi, T. M., Chen, C., Mancuso, P., Sariyer, R., Ferrante, P., Donadoni, M., Robinson, J. A., Sillman, B., Lin, Z., Hilaire, J. R., Banoub, M., Elango, M., Gautam, N., Mosley, R. L., Poluektova, L. Y. & 12 others, McMillan, J. E., Bade, A. N., Gorantla, S., Sariyer, I. K., Burdo, T. H., Young, W. B., Amini, S., Gordon, J., Jacobson, J. M., Edagwa, B., Khalili, K. & Gendelman, H. E., Dec 1 2019, In : Nature communications. 10, 1, 2753.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
human immunodeficiency virus
Viruses
set theory
Antiviral Agents