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Structure-Activity Relationship Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Quinoxalines Medicine & Life Sciences
Assays Chemical Compounds
Fluorescence Polarization Medicine & Life Sciences
Proteins Medicine & Life Sciences
Peptides Medicine & Life Sciences

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Projects 2007 2021

Adenosine Triphosphate

Phosphorylated Form of Activated IKKbeta and Pancreatic Cancer

Natarajan, A.

National Institutes of Health


Project: Research projectExploratory/Developmental Grants

Pancreatic Neoplasms
Post Translational Protein Processing
Phospho-Specific Antibodies
Neoplasm Genes
Binding Sites
Breast Neoplasms
Fluorescence Polarization
DNA Damage
BRCA1 Protein

Research Output 2000 2018

  • 1159 Citations
  • 21 h-Index
  • 61 Article
  • 2 Review article
  • 1 Letter
1 Citations

Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy

Robb, C. M., Kour, S., Contreras, J. I., Agarwal, E., Barger, C. J., Rana, S., Sonawane, Y., Neilsen, B. K., Taylor, M., Kizhake, S., Thakare, R. N., Chowdhury, S., Wang, J., Black, J. D., Hollingsworth, M. A., Brattain, M. G. & Natarajan, A., Jan 1 2018, In : Oncotarget. 9, 4, p. 5216-5232 17 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 5
Colorectal Neoplasms
Cyclin-Dependent Kinases
1 Citations

Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy

Contreras, J. I., Robb, C. M., King, H. M., Baxter, J., Crawford, A. J., Kour, S., Kizhake, S., Sonawane, Y. A., Rana, S., Hollingsworth, M. A., Luo, X. & Natarajan, A., May 18 2018, In : ACS Chemical Biology. 13, 5, p. 1148-1152 5 p.

Research output: Contribution to journalArticle

Apoptosis Regulatory Proteins
2 Citations

Ferulic acid Dimer as a non-opioid therapeutic for acute pain

Priebe, A., Hunke, M., Tonello, R., Sonawane, Y., Berta, T., Natarajan, A., Bhuvanesh, N., Pattabiraman, M. & Chandra, S., Jun 6 2018, In : Journal of Pain Research. 11, p. 1075-1085 11 p.

Research output: Contribution to journalArticle

ferulic acid
Acute Pain
Purinergic P1 Receptors
Nervous System

Mouse pancreatic tumor model independent of tumor suppressor gene inactivation

Naramura, M. & Natarajan, A., May 1 2018, In : Pancreas. 47, 5, p. e27-e29

Research output: Contribution to journalLetter

Gene Silencing
Tumor Suppressor Genes

Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy

Rana, S., Sonawane, Y. A., Taylor, M. A., Kizhake, S., Zahid, M. & Natarajan, A., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Structure-Activity Relationship
Substitution reactions