Allen A Thomas, PhD

Assistant Professor

  • 1107 Citations
  • 13 h-Index
19952019
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Fingerprint Dive into the research topics where Allen A Thomas is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

glycolic acid Chemical Compounds
Amyloid beta-Protein Precursor Medicine & Life Sciences
Transketolase Medicine & Life Sciences
Large Neutral Amino Acid-Transporter 1 Medicine & Life Sciences
Cycloaddition Reaction Medicine & Life Sciences
Thiamine Medicine & Life Sciences
Enzyme Inhibitors Medicine & Life Sciences
Chromans Medicine & Life Sciences

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Research Output 1995 2019

  • 1107 Citations
  • 13 h-Index
  • 25 Article
  • 1 Conference article

L-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of L-histidine and L-tryptophan

Hall, C., Wolfe, H., Wells, A., Chien, H. C., Colas, C., Schlessinger, A., Giacomini, K. M. & Thomas, A. A., Aug 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 16, p. 2254-2258 5 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Triazoles
Histidine
Tryptophan
Amino Acids
6 Citations (Scopus)

Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)

Chien, H. C., Colas, C., Finke, K., Springer, S., Stoner, L., Zur, A. A., Venteicher, B., Campbell, J., Hall, C., Flint, A., Augustyn, E., Hernandez, C., Heeren, N., Hansen, L., Anthony, A., Bauer, J., Fotiadis, D., Schlessinger, A., Giacomini, K. M. & Thomas, A. A., Aug 23 2018, In : Journal of Medicinal Chemistry. 61, 16, p. 7358-7373 16 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Substrate Specificity
Amino Acids
Large Neutral Amino Acid-Transporter 1
Essential Amino Acids
13 Citations (Scopus)

LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates

Zur, A. A., Chien, H. C., Augustyn, E., Flint, A., Heeren, N., Finke, K., Hernandez, C., Hansen, L., Miller, S., Lin, L., Giacomini, K. M., Colas, C., Schlessinger, A. & Thomas, A. A., Jan 1 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 20, p. 5000-5006 7 p.

Research output: Contribution to journalArticle

Large Neutral Amino Acid-Transporter 1
Hydroxamic Acids
Carboxylic Acids
Amino Acids
Substrates
17 Citations (Scopus)

LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs

Augustyn, E., Finke, K., Zur, A. A., Hansen, L., Heeren, N., Chien, H. C., Lin, L., Giacomini, K. M., Colas, C., Schlessinger, A. & Thomas, A. A., Jun 1 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 11, p. 2616-2621 6 p.

Research output: Contribution to journalArticle

Large Neutral Amino Acid-Transporter 1
Phenylalanine
Tyrosine
Amino Acids
Aromatic Amino Acids
2 Citations (Scopus)

Mitigation of opioid off-target effects and identification of structural drivers of opioid receptor engagement for BACE-1 small molecule inhibitors

Diaz, D., Dambach, D., Siu, M., Hunt, K., Thomas, A., Lyssikatos, J., Liu, X., Lewin-Koh, S., Mccray, B. & Ford, K., Jul 24 2015, In : Toxicology Mechanisms and Methods. 25, 6, p. 478-486 9 p.

Research output: Contribution to journalArticle

Opioid Receptors
Opioid Analgesics
Safety
Molecules
Rats