Adam L Reinhardt, MD

Associate Professor

  • 148 Citations
  • 5 h-Index
20022018
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Research Output 2002 2018

  • 148 Citations
  • 5 h-Index
  • 11 Article
  • 1 Chapter
2018

A 6-month, multicenter, open-label study of fixed dose naproxen/esomeprazole in adolescent patients with juvenile idiopathic arthritis

Lovell, D. J., Dare, J. A., Francis-Sedlak, M., Ball, J., LaMoreaux, B. D., Von Scheven, E., Reinhardt, A. L., Jerath, R., Alpan, O., Gupta, R., Goldsmith, D., Zeft, A., Naddaf, H., Gottlieb, B., Jung, L. & Holt, R. J., Jun 26 2018, In : Pediatric Rheumatology. 16, 1, 41.

Research output: Contribution to journalArticle

Esomeprazole
Naproxen
Juvenile Arthritis
Stomach Ulcer
Pediatrics
34 Citations (Scopus)

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies

Montealegre Sanchez, G. A., Reinhardt, A. L., Ramsey, S., Wittkowski, H., Hashkes, P. J., Berkun, Y., Schalm, S., Murias, S., Dare, J. A., Brown, D., Stone, D. L., Gao, L., Klausmeier, T., Foell, D., De Jesus, A. A., Chapelle, D. C., Kim, H., Dill, S., Colbert, R. A., Failla, L. & 35 othersKost, B., O’Brien, M., Reynolds, J. C., Folio, L. R., Calvo, K. R., Paul, S. M., Weir, N., Brofferio, A., Soldatos, A., Biancotto, A., Cowen, E. W., Digiovanna, J. J., Gadina, M., Lipton, A. J., Hadigan, C., Holland, S. M., Fontana, J., Alawad, A. S., Brown, R. J., Rother, K. I., Heller, T., Brooks, K. M., Kumar, P., Brooks, S. R., Waldman, M., Singh, H. K., Nickeleit, V., Silk, M., Prakash, A., Janes, J. M., Ozen, S., Wakim, P. G., Brogan, P. A., Macias, W. L. & Goldbach-Mansky, R., Jul 2 2018, In : Journal of Clinical Investigation. 128, 7, p. 3041-3052 12 p.

Research output: Contribution to journalArticle

Therapeutics
Biomarkers
Viremia
Adrenal Cortex Hormones
baricitinib
2016
5 Citations (Scopus)

Erratum: Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type i IFN production (Journal of Clinical Investigation (2015) 125:11 (4196-4211) DOI: 10.1172/JCI81260)

Brehm, A., Liu, Y., Sheikh, A., Marrero, B., Omoyinmi, E., Zhou, Q., Montealegre, G., Biancotto, A., Reinhardt, A. L., De Jesus, A. A., Pelletier, M., Tsai, W. L., Remmers, E. F., Kardava, L., Hill, S., Kim, H., Lachmann, H. J., Megarbane, A., Chae, J. J., Brady, J. & 23 othersCastillo, R. D., Brown, D., Casano, A. V., Gao, L., Chapelle, D., Huang, Y., Stone, D., Chen, Y., Sotzny, F., Lee, C. C. R., Kastner, D. L., Torrelo, A., Zlotogorski, A., Moir, S., Gadina, M., McCoy, P., Wesley, R., Rother, K. I., Hildebrand, P. W., Brogan, P., Krüger, E., Aksentijevich, I. & Goldbach-Mansky, R., Feb 1 2016, In : Journal of Clinical Investigation. 126, 2, p. 795 1 p.

Research output: Contribution to journalArticle

2015
75 Citations (Scopus)

Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type i IFN production

Brehm, A., Liu, Y., Sheikh, A., Marrero, B., Omoyinmi, E., Zhou, Q., Montealegre, G., Biancotto, A., Reinhardt, A. L., De Jesus, A. A., Pelletier, M., Tsai, W. L., Remmers, E. F., Kardava, L., Hill, S., Kim, H., Lachmann, H. J., Megarbane, A., Chae, J. J., Brady, J. & 23 othersCastillo, R. D., Brown, D., Casano, A. V., Gao, L., Chapelle, D., Huang, Y., Stone, D., Chen, Y., Sotzny, F., Lee, C. C. R., Kastner, D. L., Torrelo, A., Zlotogorski, A., Moir, S., Gadina, M., McCoy, P., Wesley, R., Rother, K., Hildebrand, P. W., Brogan, P., Krüger, E., Aksentijevich, I. & Goldbach-Mansky, R., Nov 2 2015, In : Journal of Clinical Investigation. 125, 11, p. 4196-4211 16 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Mutation
Small Interfering RNA
Genes
Lipodystrophy
2 Citations (Scopus)

Effect of dexamethasone prodrug on inflamed temporomandibular joints in juvenile rats

Knudsen, M., Bury, M., Holwegner, C., Reinhardt, A. L., Yuan, F., Zhang, Y., Giannini, P. J., Marx, D. B., Wang, D. & Reinhardt, R. A., Sep 24 2015, (Accepted/In press) In : Arthritis Research and Therapy.

Research output: Contribution to journalArticle

Temporomandibular Joint
Prodrugs
Dexamethasone
Inflammation
Freund's Adjuvant
8 Citations (Scopus)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Bone Development
Temporomandibular Joint
Simvastatin
Arthritis
9 Citations (Scopus)

Preliminary response to Janus kinase inhibition with baricitinib in chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperatures (CANDLE)

Montealegre, G., Reinhardt, A. L., Brogan, P., Berkun, Y., Zlotogorski, A., Brown, D., Chira, P., Gao, L., Dare, J., Schalm, S., Merino, R., Chapelle, D., Kim, H., Judd, S., O'Brien, M., De Jesus, A. A., Kim, Y., Kost, B., Huang, Y., Paul, S. & 7 othersBrofferio, A., Lee, C. C., Hadigan, C., Heller, T., Minniti, C., Rother, K. & Goldbach-Mansky, R., Sep 28 2015, In : Pediatric Rheumatology. 13, 1, O31.

Research output: Contribution to journalArticle

Stratification of patients with autoinflammatory phenotypes by interferon (IFN) score suggests a new group of IFN mediated autoinflammatory diseases with overlapping clinical phenotypes

de Jesus, A. A., Deng, Z., Brooks, S., Kim, H., Montealegre, G., Chapelle, D., Liu, Y., Marrero, B., Malle, L., O'Brien, M., Goodspeed, W., Huang, Y., Hashkes, P., Nasrullayeva, G., Terreri, M. T., Silva, C., Arabshahi, B., O'Neill, K., Punaro, M., Moorthy, L. & 6 othersReinhardt, A. L., Lilleby, V., Niemela, J., Rosenzweig, S., Fleisher, T. & Goldbach-Mansky, R., Sep 28 2015, In : Pediatric Rheumatology. 13, 1, O35.

Research output: Contribution to journalArticle

2013
12 Citations (Scopus)

Effect of simvastatin injections on temporomandibular joint inflammation in growing rats

George, M. D., Owen, C. M., Reinhardt, A. L., Giannini, P. J., Marx, D. B. & Reinhardt, R. A., May 2013, In : Journal of Oral and Maxillofacial Surgery. 71, 5, p. 846-853 8 p.

Research output: Contribution to journalArticle

Simvastatin
Temporomandibular Joint
Inflammation
Injections
Freund's Adjuvant

Juvenile idiopathic arthritis

Reinhardt, A. L. & Craig, S., Jan 1 2013, Rheumatology: A Color Handbook. CRC Press, p. 103-112 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Juvenile Arthritis
Joint Diseases
Arthritis
Joints
2007

Gene therapy for rheumatoid arthritis

Reinhardt, A. L. & Hirsch, R., Aug 2007, In : Future Rheumatology. 2, 4, p. 403-413 11 p.

Research output: Contribution to journalArticle

Genetic Therapy
Rheumatoid Arthritis
Biological Therapy
Biological Factors
Half-Life
2002
3 Citations (Scopus)

Effects of locally-delivered human macrophage products and estrogen on murine inflammatory bone resorption

Crump, T. B., Wimmer, K. L., Reinhardt, A. L., Schmid, M. J., Meyer, C. R., Robinson, D. H., Marx, D. B., Bhattacharyya, I. & Reinhardt, R. A., Apr 2002, In : Journal of Periodontal Research. 37, 2, p. 101-109 9 p.

Research output: Contribution to journalArticle

Bone Resorption
Lipopolysaccharides
Estrogens
Gels
Macrophages