Office of Research & Creative Activity

Research Output 1989 2020

2020

Stochastic expression of sae-dependent virulence genes during staphylococcus aureus biofilm development is dependent on saes

Delmain, E. A., Moormeier, D. E., Endres, J. L., Hodges, R. E., Sadykov, M. R., Horswill, A. R. & Bayles, K. W., Jan 1 2020, In : mBio. 11, 1, e03081-19.

Research output: Contribution to journalArticle

Open Access
Biofilms
Virulence
Staphylococcus aureus
Genes
Alleles

Supervised walking exercise therapy improves gait biomechanics in patients with peripheral artery disease

Schieber, M. N., Pipinos, I. I., Johanning, J. M., Casale, G. P., Williams, M. A., DeSpiegelaere, H. K., Senderling, B. & Myers, S. A., Feb 2020, In : Journal of vascular surgery. 71, 2, p. 575-583 9 p.

Research output: Contribution to journalArticle

Exercise Therapy
Peripheral Arterial Disease
Gait
Biomechanical Phenomena
Walking
2019
Near-Infrared Spectroscopy
Peripheral Arterial Disease
Walking
Lower Extremity
Atherosclerosis
Open Access
Ankle
Extremities
Motor Cortex
Frontal Lobe
Confidence Intervals

CidR and CcpA synergistically regulate staphylococcus aureus cidABC expression

Sadykov, M. R., Windham, I. H., Widhelm, T. J., Yajjala, V. K., Watson, S. M., Endres, J. L., Bavari, A. I., Thomas, V. C., Bose, J. L. & Bayles, K. W., Dec 1 2019, In : Journal of bacteriology. 201, 23, e00371-19.

Research output: Contribution to journalArticle

Staphylococcal Protein A
Operon
Staphylococcus aureus
Biofilms
Carbon

Construction of a Sequence-Defined Transposon Mutant Library in Staphylococcus aureus

Endres, J. L., Yajjala, V. K., Fey, P. D. & Bayles, K. W., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 29-37 9 p. (Methods in Molecular Biology; vol. 2016).

Research output: Chapter in Book/Report/Conference proceedingChapter

Staphylococcus aureus
Bacterial Genomes
Insertional Mutagenesis
Mutagenesis
Genes
1 Citation (Scopus)
Peripheral Arterial Disease
Mechanics
Gait
Torque
Knee

Identification of extracellular DNA-binding proteins in the biofilm matrix

Kavanaugh, J. S., Flack, C. E., Lister, J., Ricker, E. B., Ibberson, C. B., Jenul, C., Moormeier, D. E., Delmain, E. A., Bayles, K. W. & Horswill, A. R., May 1 2019, In : mBio. 10, 3, e01137-19.

Research output: Contribution to journalArticle

Open Access
DNA-Binding Proteins
Biofilms
Lipoproteins
DNA
Staphylococcus aureus

Observations of shear stress effects on Staphylococcus aureus biofilm formation

Sherman, E., Bayles, K., Moormeier, D., Endres, J. & Wei, T., Jan 1 2019, In : mSphere. 4, 4, e00372-19.

Research output: Contribution to journalArticle

Open Access
Biofilms
Staphylococcus aureus
Human Body
Veins
Catheters
1 Citation (Scopus)

Optic flow improves step width and length in older adults while performing dual task

Leeder, T., Fallahtafti, F., Schieber, M., Myers, S. A., Blaskewicz Boron, J. & Yentes, J. M., Aug 1 2019, In : Aging Clinical and Experimental Research. 31, 8, p. 1077-1086 10 p.

Research output: Contribution to journalArticle

Optic Flow
Young Adult
Walking
Gait
Costs and Cost Analysis
1 Citation (Scopus)

Quantification of Daily Physical Activity and Sedentary Behavior of Claudicating Patients

Hernandez, H., Myers, S. A., Schieber, M., Ha, D. M., Baker, S., Koutakis, P., Kim, K. S., Mietus, C., Casale, G. P. & Pipinos, I. I., Feb 2019, In : Annals of Vascular Surgery. 55, p. 112-121 10 p.

Research output: Contribution to journalArticle

Exercise
Light
Peripheral Arterial Disease
Metabolic Equivalent
Independent Living
1 Citation (Scopus)

Walking speed and spatiotemporal step mean measures are reliable during feedback-controlled treadmill walking; however, spatiotemporal step variability is not reliable

Wiens, C., Denton, W., Schieber, M. N., Hartley, R., Marmelat, V., Myers, S. A. & Yentes, J. M., Jan 23 2019, In : Journal of Biomechanics. 83, p. 221-226 6 p.

Research output: Contribution to journalArticle

Exercise equipment
Walking
Feedback
Gait
Walking Speed
2018
3 Citations (Scopus)

Guanine limitation results in CodY-dependent and -independent alteration of Staphylococcus aureus physiology and gene expression

King, A. N., Borkar, S. A., Samuels, D. J., Batz, Z., Bulock, L. L., Sadykov, M. R., Bayles, K. W. & Brinsmade, S. R., Jul 1 2018, In : Journal of bacteriology. 200, 14, e00136-18.

Research output: Contribution to journalArticle

Guanosine
Guanine
Staphylococcus aureus
Isoleucine
Valine
5 Citations (Scopus)

Nutritional regulation of the Sae two-component system by CodY in Staphylococcus aureus

Mlynek, K. D., Sause, W. E., Moormeier, D. E., Sadykov, M. R., Hill, K. R., Torres, V. J., Bayles, K. W. & Brinsmade, S. R., Apr 1 2018, In : Journal of bacteriology. 200, 8, e00012-18.

Research output: Contribution to journalArticle

Staphylococcus aureus
Gene Expression
Virulence
Cytotoxins
Virulence Factors
14 Citations (Scopus)

Ratiometric Fluorescent Sensor Array as a Versatile Tool for Bacterial Pathogen Identification and Analysis

Svechkarev, D., Sadykov, M. R., Bayles, K. W. & Mohs, A. M., Mar 23 2018, In : ACS Sensors. 3, 3, p. 700-708 9 p.

Research output: Contribution to journalArticle

pathogens
Sensor arrays
Pathogens
sensors
Discriminant analysis
2017
2 Citations (Scopus)

Attention is associated with postural control in those with chronic ankle stability

Rosen, A. B., Than, N. T., Smith, W. Z., Yentes, J. M., McGrath, M. L., Mukherjee, M., Myers, S. A. & Maerlender, A. C., May 1 2017, In : Gait and Posture. 54, p. 34-38 5 p.

Research output: Contribution to journalArticle

Ankle
Vital Signs
Pressure
Intrinsic Factor
Extremities
1 Citation (Scopus)

Gait deficiencies associated with peripheral artery disease are different than chronic obstructive pulmonary disease

McCamley, J. D., Pisciotta, E. J., Yentes, J. M., Wurdeman, S. R., Rennard, S. I., Pipinos, I. I., Johanning, J. M. & Myers, S. A., Sep 2017, In : Gait and Posture. 57, p. 258-264 7 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Gait
Chronic Obstructive Pulmonary Disease
Walking
Muscles
9 Citations (Scopus)

Muscle strength and control characteristics are altered by peripheral artery disease

Schieber, M. N., Hasenkamp, R. M., Pipinos, I. I., Johanning, J. M., Stergiou, N., DeSpiegelaere, H. K., Chien, J. H. & Myers, S. A., Jul 2017, In : Journal of vascular surgery. 66, 1, p. 178-186.e12

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Muscle Strength
Pain
Torque
Leg

Poly(3-hydroxybutyrate) fuels the tricarboxylic acid cycle and de novo lipid biosynthesis during Bacillus anthracis sporulation

Sadykov, M. R., Ahn, J. S., Widhelm, T. J., Eckrich, V. M., Endres, J. L., Driks, A., Rutkowski, G. E., Wingerd, K. L. & Bayles, K. W., Jun 2017, In : Molecular Microbiology. 104, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

Bacillus anthracis
Citric Acid Cycle
Spores
Lipids
Bacillus
3 Citations (Scopus)

Reliability of a feedback-controlled treadmill algorithm dependent on the user's behavior

Wiens, C., Denton, W., Schieber, M. N., Hartley, R., Marmelat, V., Myers, S. A. & Yentes, J. M., Sep 27 2017, 2017 IEEE International Conference on Electro Information Technology, EIT 2017. IEEE Computer Society, p. 545-550 6 p. 8053423. (IEEE International Conference on Electro Information Technology).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Exercise equipment
Feedback
12 Citations (Scopus)

Simple synthesis of endophenazine G and other phenazines and their evaluation as anti-methicillin-resistant Staphylococcus aureus agents

Conda Sheridan, M., Udumula, V., Endres, J. L., Harper, C. N., Jaramillo, L., Zhong, H. A. & Bayles, K. W., Jan 1 2017, In : European Journal of Medicinal Chemistry. 125, p. 710-721 12 p.

Research output: Contribution to journalArticle

Phenazines
Methicillin
Methicillin-Resistant Staphylococcus aureus
Biological Products
Health
45 Citations (Scopus)

Staphylococcus aureus biofilm: a complex developmental organism

Moormeier, D. E. & Bayles, K. W., May 2017, In : Molecular Microbiology. 104, 3, p. 365-376 12 p.

Research output: Contribution to journalReview article

Biofilms
Staphylococcus aureus
Population
Anti-Bacterial Agents
Morbidity
3 Citations (Scopus)

Staphylococcus aureus CidC Is a Pyruvate:Menaquinone Oxidoreductase

Zhang, X., Bayles, K. W. & Luca, S., Sep 12 2017, In : Biochemistry. 56, 36, p. 4819-4829 11 p.

Research output: Contribution to journalArticle

Pyruvate Synthase
Vitamin K 2
Cell death
Pyruvic Acid
Staphylococcus aureus
2 Citations (Scopus)

Step Activity and 6-Minute Walk Test Outcomes When Wearing Low-Activity or High-Activity Prosthetic Feet

Wurdeman, S. R., Schmid, K. K., Myers, S. A., Jacobsen, A. L. & Stergiou, N., May 1 2017, In : American Journal of Physical Medicine and Rehabilitation. 96, 5, p. 294-300 7 p.

Research output: Contribution to journalArticle

Foot
Walk Test
Heel
Amputation
Ankle
2016
6 Citations (Scopus)

Allelic exchange

Lehman, M. K., Bose, J. L. & Bayles, K. W., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 89-96 8 p. (Methods in Molecular Biology; vol. 1373).

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular Biology
Mutation
Microbial Drug Resistance
Point Mutation
Staphylococcus aureus
19 Citations (Scopus)

Effects of low-dose amoxicillin on Staphylococcus aureus USA300 biofilms

Mlynek, K. D., Callahan, M. T., Shimkevitch, A. V., Farmer, J. T., Endres, J. L., Marchand, M., Bayles, K. W., Horswill, A. R. & Kaplan, J. B., May 2016, In : Antimicrobial Agents and Chemotherapy. 60, 5, p. 2639-2651 13 p.

Research output: Contribution to journalArticle

Amoxicillin
Biofilms
Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus
Lactams
3 Citations (Scopus)

Gait kinematics and kinetics are affected more by peripheral arterial disease than by age

Myers, S. A., Applequist, B. C., Huisinga, J. M., Pipinos, I. I. & Johanning, J. M., Jan 1 2016, In : Journal of Rehabilitation Research and Development. 53, 2, p. 229-238 10 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Gait
Biomechanical Phenomena
Torque
Ankle
3 Citations (Scopus)

Generation of a transposon mutant library in staphylococcus aureus and staphylococcus epidermidis using bursa aurealis

Yajjala, V. K., Widhelm, T. J., Endres, J. L., Fey, P. D. & Bayles, K. W., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 103-110 8 p. (Methods in Molecular Biology; vol. 1373).

Research output: Chapter in Book/Report/Conference proceedingChapter

Staphylococcus epidermidis
Staphylococcus aureus
Genes
Genetic Phenomena
DNA Sequence Analysis
7 Citations (Scopus)

Identification of inhibitors for single-stranded DNA-binding proteins in eubacteria

Glanzer, J. G., Endres, J. L., Byrne, B. M., Liu, S., Bayles, K. W. & Oakley, G. G., Jan 1 2016, In : Journal of Antimicrobial Chemotherapy. 71, 12, p. 3432-3440 9 p.

Research output: Contribution to journalArticle

Open Access
DNA-Binding Proteins
Francisella tularensis
Bacillus anthracis
Gram-Positive Bacteria
Bacteria
2 Citations (Scopus)

Optic flow improves adaptability of spatiotemporal characteristics during split-belt locomotor adaptation with tactile stimulation

Eikema, D. J. A., Chien, J. H., Stergiou, N., Myers, S. A., Scott-Pandorf, M. M., Bloomberg, J. J. & Mukherjee, M., Feb 1 2016, In : Experimental Brain Research. 234, 2, p. 511-522 12 p.

Research output: Contribution to journalArticle

Optic Flow
Touch
Walking
Photic Stimulation
Vibration
5 Citations (Scopus)

Potassium uptake modulates Staphylococcus aureus metabolism

Gries, C. M., Sadykov, M. R., Bulock, L. L., Chaudhari, S. S., Chittezham Thomas, V., Bose, J. L. & Bayles, K. W., May 1 2016, In : mSphere. 1, 3, e00125-16.

Research output: Contribution to journalArticle

Staphylococcus aureus
Potassium
Homeostasis
Carbon Cycle
Proton-Motive Force
7 Citations (Scopus)

Redox Imbalance Underlies the Fitness Defect Associated with Inactivation of the Pta-AckA Pathway in Staphylococcus aureus

Marshall, D. D., Sadykov, M. R., Chittezham Thomas, V., Bayles, K. W. & Powers, R., Apr 1 2016, In : Journal of proteome research. 15, 4, p. 1205-1212 8 p.

Research output: Contribution to journalArticle

Phosphate Acetyltransferase
Acetate Kinase
Oxidation-Reduction
Staphylococcus aureus
Metabolism
6 Citations (Scopus)

Resistance to acute macrophage killing promotes airway fitness of prevalent community-acquired staphylococcus aureus strains

Yajjala, V. K., Chittezham Thomas, V., Bauer, C., Scherr, T. D., Fischer, K. J., Fey, P. D., Bayles, K. W., Kielian, T. L. & Sun, K., May 15 2016, In : Journal of Immunology. 196, 10, p. 4196-4203 8 p.

Research output: Contribution to journalArticle

Methicillin-Resistant Staphylococcus aureus
Staphylococcus aureus
Macrophages
Infection
Staphylococcal Pneumonia
11 Citations (Scopus)

SrrAB modulates Staphylococcus aureus cell death through regulation of cidABC transcription

Windham, I. H., Chaudhari, S. S., Bose, J. L., Chittezham Thomas, V. & Bayles, K. W., Jan 1 2016, In : Journal of bacteriology. 198, 7, p. 1114-1122 9 p.

Research output: Contribution to journalArticle

Staphylococcus aureus
Cell Death
Operon
Biofilms
Reactive Oxygen Species
2 Citations (Scopus)

Surrogation

Myers, S. A., Jan 6 2016, Nonlinear Analysis for Human Movement Variability. CRC Press, p. 111-172 62 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Citations (Scopus)

The LysR-type transcriptional regulator, CidR, regulates stationary phase cell death in Staphylococcus aureus

Chaudhari, S. S., Chittezham Thomas, V., Sadykov, M. R., Bose, J. L., Ahn, D. J., Zimmerman, M. C. & Bayles, K. W., Sep 1 2016, In : Molecular Microbiology. 101, 6, p. 942-953 12 p.

Research output: Contribution to journalArticle

Regulon
Operon
Staphylococcus aureus
Acetates
Cell Death
4 Citations (Scopus)

The major autolysin is redundant for Staphylococcus aureus USA300 LAC JE2 virulence in a murine device-related infection model

McCarthy, H., Waters, E. M., Bose, J. L., Foster, S., Bayles, K. W., O'Neill, E., Fey, P. D. & O'Gara, J. P., Apr 3 2016, In : FEMS Microbiology Letters. 363, 9, fnw087.

Research output: Contribution to journalArticle

N-Acetylmuramoyl-L-alanine Amidase
Biofilms
Virulence
Staphylococcus aureus
Equipment and Supplies
2 Citations (Scopus)

Time series

Myers, S. A., Jan 6 2016, Nonlinear Analysis for Human Movement Variability. CRC Press, p. 29-54 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Time series
2015
20 Citations (Scopus)
Desmin
Peripheral Arterial Disease
Extremities
Muscles
Muscular Diseases
16 Citations (Scopus)

Abnormal myofiber morphology and limb dysfunction in claudication

Koutakis, P., Myers, S. A., Cluff, K., Ha, D. M., Haynatzki, G., McComb, R. D., Uchida, K., Miserlis, D., Papoutsi, E., Johanning, J. M., Casale, G. P. & Pipinos, I. I., Jun 1 2015, In : Journal of Surgical Research. 196, 1, p. 172-179 8 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Extremities
Walking
Muscle Strength
Muscles
17 Citations (Scopus)

Examination of the Staphylococcus aureus nitric oxide reductase (saNOR) reveals its contribution to modulating intracellular NO levels and cellular respiration

Lewis, A. M., Matzdorf, S. S., Endres, J. L., Windham, I. H., Bayles, K. W. & Rice, K. C., May 1 2015, In : Molecular Microbiology. 96, 3, p. 651-669 19 p.

Research output: Contribution to journalArticle

Cell Respiration
Staphylococcus aureus
Nitric Oxide
Biofilms
Growth
23 Citations (Scopus)

Identification of the amino acids essential for LytSR-mediated signal transduction in Staphylococcus aureus and their roles in biofilm-specific gene expression

Lehman, M. K., Bose, J. L., Sharma-Kuinkel, B. K., Moormeier, D. E., Endres, J. L., Sadykov, M. R., Biswas, I. & Bayles, K. W., Feb 1 2015, In : Molecular Microbiology. 95, 4, p. 723-737 15 p.

Research output: Contribution to journalArticle

Essential Amino Acids
Biofilms
Staphylococcus aureus
Signal Transduction
Gene Expression

Increased minimum toe clearance variability in patients with peripheral arterial disease

Rand, T. J., Wurdeman, S. R., Johanning, J. M., Pipinos, I. I. & Myers, S. A., Dec 1 2015, In : Medical Engineering and Physics. 37, 12, p. 1141-1145 5 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Toes
Exercise equipment
Pain
Patient rehabilitation
6 Citations (Scopus)

Plantar tactile perturbations enhance transfer of split-belt locomotor adaptation

Mukherjee, M., Eikema, D. J. A., Chien, J. H., Myers, S. A., Scott-Pandorf, M., Bloomberg, J. J. & Stergiou, N., Oct 26 2015, In : Experimental Brain Research. 233, 10, p. 3005-3012 8 p.

Research output: Contribution to journalArticle

Touch
Gait
Walking
Learning
Locomotion
1 Citation (Scopus)

Spatiotemporal Changes Posttreatment in Peripheral Arterial Disease

Myers, S. A., Huben, N. B., Yentes, J. M., McCamley, J. D., Lyden, E. R., Pipinos, I. I. & Johanning, J. M., Jan 1 2015, In : Rehabilitation Research and Practice. 2015, 124023.

Research output: Contribution to journalReview article

Peripheral Arterial Disease
Gait
Exercise
Extremities
Pathology
53 Citations (Scopus)

Staphylococcus aureus biofilms induce macrophage dysfunction through leukocidin AB and alpha-toxin

Scherr, T. D., Hanke, M. L., Huang, O., James, D. B. A., Horswill, A. R., Bayles, K. W., Fey, P. D., Torres, V. J. & Kielian, T. L., Aug 25 2015, In : mBio. 6, 4, e01021-15.

Research output: Contribution to journalArticle

Leukocidins
Biofilms
Staphylococcus aureus
Macrophages
Phagocytosis
6 Citations (Scopus)

Temporal Structure of Support Surface Translations Drive the Temporal Structure of Postural Control During Standing

Rand, T. J., Myers, S. A., Kyvelidou, A. & Mukherjee, M., Nov 1 2015, In : Annals of biomedical engineering. 43, 11, p. 2699-2707 9 p.

Research output: Contribution to journalArticle

Time series
Biological systems
White noise
Analysis of variance (ANOVA)
Patient rehabilitation
2014
40 Citations (Scopus)

A Central Role for Carbon-Overflow Pathways in the Modulation of Bacterial Cell Death

Chittezham Thomas, V., Sadykov, M. R., Chaudhari, S. S., Jones, J., Endres, J. L., Widhelm, T. J., Ahn, J. S., Jawa, R. S., Zimmerman, M. C. & Bayles, K. W., Jun 2014, In : PLoS pathogens. 10, 6, e1004205.

Research output: Contribution to journalArticle

Cell Death
Carbon
Biofilms
acetolactate decarboxylase
Acetolactate Synthase
18 Citations (Scopus)

Adaptation and prosthesis effects on stride-to-stride fluctuations in amputee gait

Wurdeman, S. R., Myers, S. A., Jacobsen, A. L. & Stergiou, N., Jun 23 2014, In : PloS one. 9, 6, e100125.

Research output: Contribution to journalArticle

Amputees
prostheses
gait
Gait
Ankle
11 Citations (Scopus)

Amputation effects on the underlying complexity within transtibial amputee ankle motion

Wurdeman, S. R., Myers, S. A. & Stergiou, N., Mar 1 2014, In : Chaos (Woodbury, N.Y.). 24, 1, 1 p.

Research output: Contribution to journalArticle

Amputees
Prosthetics
Amputation
Ankle
Prostheses and Implants