Research Output 1973 2020

2020

Antimicrobial therapy utilization in neonates with hypoxic-ischemic encephalopathy (HIE): a report from the Children’s Hospital Neonatal Database (CHND)

Rao, R., Lee, K. S., Zaniletti, I., Yanowitz, T. D., DiGeronimo, R., Dizon, M. L. V., Hamrick, S. E., Natarajan, G., Peeples, E. S., Murthy, K., Mathur, A. M. & Massaro, A., Jan 1 2020, In : Journal of Perinatology. 40, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

Brain Hypoxia-Ischemia
Newborn Infant
Databases
Infection
Therapeutics
2019
2 Citations (Scopus)

Many newborns in level IV NICUs are eligible for rapid DNA sequencing

Kapil, S., Fishler, K. P., Euteneuer, J. C. & Brunelli, L., Feb 1 2019, In : American Journal of Medical Genetics, Part A. 179, 2, p. 280-284 5 p.

Research output: Contribution to journalLetter

DNA Sequence Analysis

Outcomes of extremely low birth weight infants in the NICU after initiation of a two-team care model

Chabra, S., Strandjord, T. P. & Peeples, E. S., Oct 2019, In : Journal of Neonatal Nursing. 25, 5, p. 254-256 3 p.

Research output: Contribution to journalArticle

Extremely Low Birth Weight Infant
Nurse Practitioners
Neonatal Intensive Care Units
Retinopathy of Prematurity
Chi-Square Distribution

Prolonged non-invasive ventilation in extremely low birth weight preterm infants is associated with bronchopulmonary dysplasia

Chabra, S., Strandjord, T. & Peeples, E., Jan 1 2019, In : Journal of Neonatal-Perinatal Medicine. 12, 3, p. 249-253 5 p.

Research output: Contribution to journalArticle

Extremely Low Birth Weight Infant
Noninvasive Ventilation
Bronchopulmonary Dysplasia
Intermittent Positive-Pressure Ventilation
Premature Infants
3 Citations (Scopus)

Strategies for the use of Extracellular Vesicles for the Delivery of Therapeutics

Sil, S., Dagur, R. S., Liao, K., Peeples, E. S., Hu, G., Periyasamy, P. & Buch, S., Jan 1 2019, (Accepted/In press) In : Journal of Neuroimmune Pharmacology.

Research output: Contribution to journalReview article

Therapeutics
Long Noncoding RNA
Prokaryotic Cells
Lipids
Immunomodulation

Targeted gene panel sequencing for the rapid diagnosis of acutely ill infants

Brunelli, L., Jenkins, S. M., Gudgeon, J. M., Bleyl, S. B., Miller, C. E., Tvrdik, T., Dames, S. A., Ostrander, B., Daboub, J. A. F., Zielinski, B. A., Zinkhan, E. K., Underhill, H. R., Wilson, T., Bonkowsky, J. L., Yost, C. C., Botto, L. D., Jenkins, J., Pysher, T. J., Bayrak-Toydemir, P. & Mao, R., Jul 2019, In : Molecular Genetics and Genomic Medicine. 7, 7, e00796.

Research output: Contribution to journalArticle

Open Access
Genes
Congenital Myasthenic Syndromes
Exome
Pediatric Intensive Care Units
Heterozygote
Postpartum Depression
Brain Diseases
Mothers
Induced Hypothermia
Marital Status
2018
Molecular Pathology
Clostridium difficile
Neonatal Intensive Care Units
Polymerase Chain Reaction
Essential Genes
1 Citation (Scopus)

Evaluating a Targeted Bedside Measure of Cerebral Perfusion in a Nonhuman Primate Model of Neonatal Hypoxic-Ischemic Encephalopathy

Peeples, E. S., Ezeokeke, C. K., Juul, S. E. & Mourad, P. D., Apr 2018, In : Journal of Ultrasound in Medicine. 37, 4, p. 913-920 8 p.

Research output: Contribution to journalArticle

Brain Hypoxia-Ischemia
Anterior Cerebral Artery
Primates
Umbilical Cord
Hypothermia
1 Citation (Scopus)

From cord to caudate: Characterizing umbilical cord blood stem cells and their paracrine interactions with the injured brain

Maillacheruvu, P. F., Engel, L. M., Crum, I. T., Agrawal, D. K. & Peeples, E. S., Jan 1 2018, In : Pediatric Research. 83, 1-2, p. 205-213 9 p.

Research output: Contribution to journalReview article

Fetal Blood
Blood Cells
Stem Cells
Brain
Stem Cell Transplantation

Germline but not somatic de novo mutations are common in human congenital diaphragmatic hernia

Matsunami, N., Shanmugam, H., Baird, L., Stevens, J., Byrne, J. L., Barnhart, D. C., Rau, C., Feldkamp, M. L., Yoder, B. A., Leppert, M. F., Yost, H. J. & Brunelli, L., Apr 17 2018, In : Birth Defects Research. 110, 7, p. 610-617 8 p.

Research output: Contribution to journalArticle

Genes
Diaphragms
Mutation
Diaphragm
Frameshift Mutation
Open Access
Brain Hypoxia-Ischemia
Animal Models
Magnetic Resonance Imaging
Brain Injuries
Abruptio Placentae
1 Citation (Scopus)

The impact of hypoxic-ischemic brain injury on stem cell mobilization, migration, adhesion, and proliferation

Parry, S. & Peeples, E. S., Jul 2018, In : Neural Regeneration Research. 13, 7, p. 1125-1135 11 p.

Research output: Contribution to journalReview article

Hematopoietic Stem Cell Mobilization
Brain Injuries
Cell Movement
Brain Hypoxia-Ischemia
Stem Cells
2 Citations (Scopus)

Vitamin D and Its Role in Neonatal Hypoxic-Ischemic Brain Injury

Stessman, L. E. & Peeples, E. S., May 1 2018, In : Neonatology. 113, 4, p. 305-312 8 p.

Research output: Contribution to journalReview article

Brain Hypoxia-Ischemia
Vitamin D
Brain Injuries
Newborn Infant
Mothers
2017
3 Citations (Scopus)

An evaluation of hydrocortisone dosing for neonatal refractory hypotension

Peeples, E. S., Aug 1 2017, In : Journal of Perinatology. 37, 8, p. 943-946 4 p.

Research output: Contribution to journalArticle

Hypotension
Hydrocortisone
Premature Infants
Hyperglycemia
Gestational Age
4 Citations (Scopus)

A rapid gene sequencing panel strategy to facilitate precision neonatal medicine

Brunelli, L., Mao, R., Jenkins, S. M., Bleyl, S. B., Dames, S. A., Miller, C. E., Ostrander, B., Tvrdik, T., Andrews, S., Flores, J., Patel, S., Gudgeon, J. M. & Schaefer, S., Jul 2017, In : American Journal of Medical Genetics, Part A. 173, 7, p. 1979-1982 4 p.

Research output: Contribution to journalLetter

Direct isolation of seamless mutant bacterial artificial chromosomes

Lyozin, G. T., Kosaka, Y., Bhattacharje, G., Yost, H. J. & Brunelli, L., Apr 1 2017, In : Current Protocols in Molecular Biology. 2017, p. 8.6.1-8.6.29

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Genetic Engineering
Genetic Recombination
Polymerase Chain Reaction
Mutation
13 Citations (Scopus)

Epidemiology and Prognosis of Congenital Diaphragmatic Hernia: A Population-Based Cohort Study in Utah

Shanmugam, H., Brunelli, L., Botto, L. D., Krikov, S. & Feldkamp, M. L., Nov 1 2017, In : Birth Defects Research. 109, 18, p. 1451-1459 9 p.

Research output: Contribution to journalArticle

Epidemiology
Cohort Studies
Liver
Population
Stillbirth
2016
4 Citations (Scopus)

14-3-3epsilon controls multiple developmental processes in the mouse heart

Gittenberger-de Groot, A. C., Hoppenbrouwers, T., Miquerol, L., Kosaka, Y., Poelmann, R. E., Wisse, L. J., Yost, H. J., Jongbloed, M. R. M., Deruiter, M. C. & Brunelli, L., Nov 1 2016, In : Developmental Dynamics. 245, 11, p. 1107-1123 17 p.

Research output: Contribution to journalArticle

Ventricular Heart Septal Defects
Endocardial Cushions
Tricuspid Atresia
Branchial Region
Epithelial-Mesenchymal Transition

Evaluating an Association between Ampicillin and Intraventricular Hemorrhage in Preterm Infants

Peeples, E. S., Strandjord, T. P. & Juul, S. E., Aug 1 2016, In : Neuropediatrics. 47, 4, p. 221-225 5 p.

Research output: Contribution to journalArticle

Ampicillin
Premature Infants
Hemorrhage
Odds Ratio
Lactams
5 Citations (Scopus)

Fast Doppler as a novel bedside measure of cerebral perfusion in preterm infants

Peeples, E. S., Mehic, E., Mourad, P. D. & Juul, S. E., Mar 1 2016, In : Pediatric Research. 79, 2, p. 333-338 6 p.

Research output: Contribution to journalArticle

Blood Flow Velocity
Premature Infants
Cerebrovascular Circulation
Perfusion
Blood Pressure
1 Citation (Scopus)

Micro-computed tomography for the quantitative 3-dimensional assessment of the compact myocardium in the mouse embryo

Merchant, S. S., Kosaka, Y., Yost, H. J., Hsu, E. W. & Brunelli, L., Jan 1 2016, In : Circulation Journal. 80, 8, p. 1795-1803 9 p.

Research output: Contribution to journalArticle

Myocardium
Embryonic Structures
Tomography
Atlases
Iodine
9 Citations (Scopus)

Seven great achievements in pediatric research in the past 40 y

Cheng, T. L., Monteiro, N., Dimeglio, L. A., Chien, A. T., Peeples, E. S., Raetz, E., Scheindlin, B. & Denne, S. C., Sep 1 2016, In : Pediatric Research. 80, 3, p. 330-337 8 p.

Research output: Contribution to journalArticle

2015
62 Citations (Scopus)

Race, ethnicity, and socioeconomic status in research on child health

Committee on Pediatric Research, Jan 1 2015, In : Pediatrics. 135, 1, p. e225-e237

Research output: Contribution to journalArticle

Social Class
Research
Healthcare Disparities
Health
Pediatrics
2014
4 Citations (Scopus)

Isolation of rare recombinants without using selectable markers for one-step seamless BACmutagenesis

Lyozin, G. T., Bressloff, P. C., Kumar, A., Kosaka, Y., Demarest, B. L., Yost, H. J., Kuehn, M. R. & Brunelli, L., Jan 1 2014, In : Nature Methods. 11, 9, p. 966-970 5 p.

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Chromosomes
Mutagenesis
Nodal Protein
P1 Bacteriophage Artificial Chromosomes
2013
12 Citations (Scopus)

14-3-3ε Gene variants in a Japanese patient with left ventricular noncompaction and hypoplasia of the corpus callosum

Chang, B., Gorbea, C., Lezin, G., Li, L., Shan, L., Sakai, N., Kogaki, S., Otomo, T., Okinaga, T., Hamaoka, A., Yu, X., Hata, Y., Nishida, N., Yost, H. J., Bowles, N. E., Brunelli, L. & Ichida, F., Feb 15 2013, In : Gene. 515, 1, p. 173-180 8 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Corpus Callosum
Cardiomyopathies
Morphogenesis
Classical Lissencephalies and Subcortical Band Heterotopias
2 Citations (Scopus)

Family-based studies to identify genetic variants that cause congenital heart defects

Arrington, C. B., Bleyl, S. B., Brunelli, L. & Bowles, N. E., Jul 1 2013, In : Future Cardiology. 9, 4, p. 507-518 12 p.

Research output: Contribution to journalReview article

Congenital Heart Defects
Genes
Genetic Heterogeneity
Nuclear Family
Technology
2012
22 Citations (Scopus)

14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle

Kosaka, Y., Cieslik, K. A., Li, L., Lezin, G., Maguire, C. T., Saijoh, Y., Toyo-oka, K., Gambello, M. J., Vatta, M., Wynshaw-Boris, A., Baldini, A., Yost, H. J. & Brunelli, L., Dec 1 2012, In : Molecular and cellular biology. 32, 24, p. 5089-5102 14 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Myocardium
Cell Cycle
Cyclins
Cardiomyopathies
19 Citations (Scopus)

A family-based paradigm to identify candidate chromosomal regions for isolated congenital diaphragmatic hernia

Arrington, C. B., Bleyl, S. B., Matsunami, N., Bowles, N. E., Leppert, T. I., Demarest, B. L., Osborne, K., Yoder, B. A., Byrne, J. L., Schiffman, J. D., Null, D. M., Digeronimo, R., Rollins, M., Faix, R., Comstock, J., Camp, N. J., Leppert, M. F., Yost, H. J. & Brunelli, L., Dec 2012, In : American Journal of Medical Genetics, Part A. 158 A, 12, p. 3137-3147 11 p.

Research output: Contribution to journalArticle

Diaphragm
Congenital Diaphragmatic Hernias
Genetic Association Studies
Regulator Genes
Introns
19 Citations (Scopus)

Loss of function of hNav1.5 by a ZASP1 mutation associated with intraventricular conduction disturbances in left ventricular noncompaction

Xi, Y., Ai, T., De Lange, E., Li, Z., Wu, G., Brunelli, L., Kyle, W. B., Turker, I., Cheng, J., Ackerman, M. J., Kimura, A., Weiss, J. N., Qu, Z., Kim, J. J., Faulkner, G. & Vatta, M., Oct 1 2012, In : Circulation: Arrhythmia and Electrophysiology. 5, 5, p. 1017-1026 10 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Mutation
LIM Domain Proteins
PDZ Domains
Kidney
2011
10 Citations (Scopus)

A one-step miniprep for the isolation of plasmid DNA and lambda phage particles

Lezin, G., Kosaka, Y., Yost, H. J., Kuehn, M. R. & Brunelli, L., Aug 19 2011, In : PloS one. 6, 8, e23457.

Research output: Contribution to journalArticle

Bacteriophage lambda
Bacteriophages
detergents
Detergents
bacteriophages
3 Citations (Scopus)

Familial Miller Fisher syndrome

Peeples, E., May 1 2011, In : Journal of Child Neurology. 26, 5, p. 645-648 4 p.

Research output: Contribution to journalArticle

Miller Fisher Syndrome
Ophthalmoplegia
Guillain-Barre Syndrome
Ataxia
6 Citations (Scopus)

Hofmeister series salts enhance purification of plasmid DNA by non-ionic detergents

Lezin, G., Kuehn, M. R. & Brunelli, L., Aug 1 2011, In : Biotechnology and Bioengineering. 108, 8, p. 1872-1882 11 p.

Research output: Contribution to journalArticle

Detergents
Purification
Plasmids
DNA
Salts

Kawasaki disease in a young boy with a neck mass

Peeples, E., Varman, M., Yaghmour, A. & Chatterjee, A., Oct 1 2011, In : Consultant. 51, 10, p. 702-704 3 p.

Research output: Contribution to journalArticle

Mucocutaneous Lymph Node Syndrome
Neck
2010
19 Citations (Scopus)

A ZASP missense mutation, S196L, leads to cytoskeletal and electrical abnormalities in a mouse model of cardiomyopathy

Li, Z., Ai, T., Samani, K., Xi, Y., Tzeng, H. P., Xie, M., Wu, S., Ge, S., Taylor, M. D., Dong, J. W., Cheng, J., Ackerman, M. J., Kimura, A., Sinagra, G., Brunelli, L., Faulkner, G. & Vatta, M., Dec 1 2010, In : Circulation: Arrhythmia and Electrophysiology. 3, 6, p. 646-656 11 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Missense Mutation
Cardiomyopathies
Sudden Cardiac Death
Mutation
49 Citations (Scopus)

Levels of neonatal thyroid hormone in preterm infants and neurodevelopmental outcome at 5 1/2 years: Millennium cohort study

Delahunty, C., Falconer, S., Hume, R., Jackson, L., Midgley, P., Mirfield, M., Ogston, S., Perra, O., Simpson, J., Watson, J., Willatts, P., Williams, F., Dunlop, J., Kinmond, S., Lloyd, D., McFadyen, U., McArthur, A., Mitchell, S., Ray, M. & Vallance, A., Nov 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 11, p. 4898-4908 11 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Premature Infants
Cohort Studies
Blood
Pharmaceutical Preparations
4 Citations (Scopus)

Neonatal PICC: one unit's six-year experience with limiting catheter complications.

Corzine, M. & Willett, L. D., Jan 1 2010, In : Neonatal network : NN. 29, 3, p. 161-173 13 p.

Research output: Contribution to journalArticle

Bandages
Catheters
2009
33 Citations (Scopus)

Mass spectrometry identifies multiple organophosphorylated sites on tubulin

Grigoryan, H., Schopfer, L. M., Peeples, E. S., Duysen, E. G., Grigoryan, M., Thompson, C. M. & Lockridge, O., Oct 15 2009, In : Toxicology and Applied Pharmacology. 240, 2, p. 149-158 10 p.

Research output: Contribution to journalArticle

Tubulin
Mass spectrometry
Mass Spectrometry
Poisons
Tyrosine
7 Citations (Scopus)

Remodeling of dystrophin and sarcomeric Z-band occurs in pediatric cardiomyopathies: A unifying mechanism for force transmission defect

Vatta, M., Sinagra, G., Brunelli, L. & Faulkner, G., Feb 1 2009, In : Journal of Cardiovascular Medicine. 10, 2, p. 149-156 8 p.

Research output: Contribution to journalArticle

Dystrophin
Cardiomyopathies
Pediatrics
Dilated Cardiomyopathy
Sarcomeres
2007
39 Citations (Scopus)

Peroxisome proliferator-activated receptor-δ upregulates 14-3-3ε in human endothelial cells via CCAAT/enhancer binding protein-β

Brunelli, L., Cieslik, K. A., Alcorn, J. L., Vatta, M. & Baldini, A., Mar 1 2007, In : Circulation Research. 100, 5, p. e59-e71

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Peroxisome Proliferator-Activated Receptors
Up-Regulation
Endothelial Cells
4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid
2006
7 Citations (Scopus)

Perfluorochemical liquids enhance delivery of superoxide dismutase to the lungs of juvenile rabbits

Brunelli, L., Hamilton, E., Davis, J. M., Koo, H. C., Joseph, A., Kazzaz, J. A., Wolfson, M. R. & Shaffer, T. H., Jul 1 2006, In : Pediatric Research. 60, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

Superoxide Dismutase
Rabbits
Lung
Acute Lung Injury
Proteins
2005
112 Citations (Scopus)

Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry

Peeples, E. S., Schopfer, L. M., Duysen, E. G., Spaulding, R., Voelker, T., Thompson, C. M. & Lockridge, O., Feb 1 2005, In : Toxicological Sciences. 83, 2, p. 303-312 10 p.

Research output: Contribution to journalArticle

Biomarkers
Mass spectrometry
Albumins
Mass Spectrometry
Carboxylesterase
2002

Gluconeogenesis in the newborn

Kalhan, S. C. & Zeidan, Z., Sep 1 2002, In : Perinatology. 4, 5, p. 245-255 11 p.

Research output: Contribution to journalArticle

Gluconeogenesis
Newborn Infant
Glucose
Glycogenolysis
Pyruvic Acid
2001
99 Citations (Scopus)

Modulation of catalase peroxidatic and catalatic activity by nitric oxide

Brunelli, L., Yermilov, V. & Beckman, J. S., Apr 1 2001, In : Free Radical Biology and Medicine. 30, 7, p. 709-714 6 p.

Research output: Contribution to journalArticle

Catalase
Nitric Oxide
Modulation
Hydrogen Peroxide
Superoxide Dismutase
37 Citations (Scopus)

Outbreak of vancomycin-resistant enterococcus faecium in a neonatal intensive care unit

Rupp, M. E., Marion, N., Fey, P. D., Bolam, D. L., Iwen, P. C., Overfelt, C. M. & Chapman, L., May 2001, In : Infection Control and Hospital Epidemiology. 22, 5, p. 301-303 3 p.

Research output: Contribution to journalArticle

Enterococcus faecium
Neonatal Intensive Care Units
Disease Outbreaks
Hand Sanitizers
Patient Isolation
2000
37 Citations (Scopus)

High-versus low-threshold surfactant retreatment for neonatal respiratory distress syndrome

Kattwinkel, J., Bloom, B. T., Delmore, P., Glick, C., Brown, D., Lopez, S., Willett, L. D., Egan, E. A., Conaway, M. & Patrie, J., Jan 1 2000, In : Pediatrics. 106, 2 I, p. 282-288 7 p.

Research output: Contribution to journalArticle

Newborn Respiratory Distress Syndrome
Retreatment
Surface-Active Agents
Oxygen
Artificial Respiration
8 Citations (Scopus)

Pre-operative coagulopathy management of a neonate with complex congenital heart disease: A case study

Stammers, A. H., Rauch, E. D., Willett, L. D., Newberry, J. W. & Duncan, K. F., Jan 1 2000, In : Perfusion. 15, 2, p. 161-168 8 p.

Research output: Contribution to journalArticle

heart disease
surgery
Heart Diseases
Newborn Infant
Coagulation
3 Citations (Scopus)

Primary transcatheter treatment of congenital pulmonary arteriovenous malformation causing cyanosis of the newborn

Fletcher, S. E., Cheatham, J. P. & Bolam, D. L., May 19 2000, In : Catheterization and Cardiovascular Interventions. 50, 1, p. 48-51 4 p.

Research output: Contribution to journalArticle

Cyanosis
Pneumonectomy
Arteriovenous Malformations
Lung
Therapeutics
1998
32 Citations (Scopus)

Hematological abnormalities in neonatal patients treated with extracorporeal membrane oxygenation (ECMO)

Zavadil, D. P., Stammers, A. H., Willett, L. D., Deptula, J. J., Christensen, K. A. & Sydzyik, R. T., Jun 1 1998, In : Journal of Extra-Corporeal Technology. 30, 2, p. 83-90 8 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Thrombelastography
Hemostasis
Physical Phenomena
Morbidity
11 Citations (Scopus)

Increased Survival in Low Birth Weight Neonates Given Prophylactic Surfactant

Brown, D. R., Bloom, B. T., Cohen, M., Myers, M. M., Egan, E. A., Kattwinkel, J., Delmore, P., Hall, R. T., Malloy, M. H., Holzman, I. R., Carlo, W. A., Pramanik, A. K., McCaffree, M. A., Weatherstone, K. B., Willett, L. D. & Topper, W. H., Nov 1 1998, In : Journal of Perinatology. 18, 6 SUPPL. 1, p. 431-435 5 p.

Research output: Contribution to journalArticle

Low Birth Weight Infant
Surface-Active Agents
Newborn Infant
Survival
Hyaline Membrane Disease