Research Output per year
Research Output 1967 2020
- 1 - 50 out of 4,644 results
- Publication Year, Title (descending)
A phase I study of weekly doxorubicin and oral topotecan for patients with relapsed or refractory small cell lung cancer (SCLC): A Fred and Pamela Buffet Cancer Center Clinical Trials Network study
Ernani, V., Jahan, R., Smith, L. M., Marr, A. S., Kimbrough, S. E., Kos, M. E., Tijerina, J., Pivovar, S., Lakshmanan, I., Ketcham, M., Rauth, S., Mallya, K., Nasser, M. W., Jain, M., Kessinger, A., Batra, S. K. & Ganti, A. K., 2020, In : Cancer Treatment and Research Communications. 22, 100162.Research output: Contribution to journal › Article
Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells
Vengoji, R., Macha, M. A., Nimmakayala, R. K., Rachagani, S., Siddiqui, J. A., Mallya, K., Gorantla, S., Jain, M., Ponnusamy, M. P., Batra, S. K. & Shonka, N., Jun 18 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 266.Research output: Contribution to journal › Article
A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery
McMillan, E. A., Kwon, G., Clemenceau, J. R., Fisher, K. W., Vaden, R. M., Shaikh, A. F., Neilsen, B. K., Kelly, D., Potts, M. B., Sung, Y. J., Mendiratta, S., Hight, S. K., Lee, Y., MacMillan, J. B., Lewis, R. E., Kim, H. S. & White, M. A., Oct 17 2019, In : Cell Chemical Biology. 26, 10, p. 1380-1392.e6Research output: Contribution to journal › Article
A Human Papillomavirus-Independent Cervical Cancer Animal Model Reveals Unconventional Mechanisms of Cervical Carcinogenesis
He, C., Lv, X., Huang, C., Angeletti, P. C., Hua, G., Dong, J., Zhou, J., Wang, Z., Ma, B., Chen, X., Lambert, P. F., Rueda, B. R., Davis, J. S. & Wang, C., Mar 5 2019, In : Cell Reports. 26, 10, p. 2636-2650.e5Research output: Contribution to journal › Article
Alendronate-Modified Polymeric Micelles for the Treatment of Breast Cancer Bone Metastasis
Liu, T., Romanova, S., Wang, S., Hyun, M. A., Zhang, C., Cohen, S. M., Singh, R. K. & Bronich, T. K., Jan 1 2019, In : Molecular Pharmaceutics.Research output: Contribution to journal › Article
A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1
Zheng, X. F., Acharya, S. S., Choe, K. N., Nikhil, K., Adelmant, G., Satapathy, S. R., Sharma, S., Viccaro, K., Rana, S., Natarajan, A., Sicinski, P., Marto, J. A., Shah, K. & Chowdhury, D., Dec 1 2019, In : Nature communications. 10, 1, 4252.Research output: Contribution to journal › Article
Amphiphilic polyanhydride-based recombinant MUC4β-nanovaccine activates dendritic cells
Banerjee, K., Gautam, S. K., Kshirsagar, P., Ross, K. A., Spagnol, G., Sorgen, P., Wannemuehler, M. J., Narasimhan, B., Solheim, J. C., Kumar, S., Batra, S. K. & Jain, M., Jan 1 2019, In : Genes and Cancer. 10, 3-4, p. 52-62 11 p.Research output: Contribution to journal › Article
Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models
Abney, K. K., Bubser, M., Du, Y., Kozek, K. A., Bridges, T. M., Linsdley, C. W., Daniels, J. S., Morrison, R. D., Wickman, K., Hopkins, C. R., Jones, C. K. & Weaver, C. D., Mar 20 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1294-1299 6 p.Research output: Contribution to journal › Article
Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models
Hollandsworth, H. M., Lwin, T. M., Amirfakhri, S., Filemoni, F., Batra, S. K., Hoffman, R. M., Dhawan, P. & Bouvet, M., Oct 2019, In : Journal of Surgical Research. 242, p. 145-150 6 p.Research output: Contribution to journal › Article
A patent review of bisphosphonates in treating bone disease
Holstein, S. A., May 4 2019, In : Expert Opinion on Therapeutic Patents. 29, 5, p. 315-325 11 p.Research output: Contribution to journal › Article
A polymeric nanogel-based treatment regimen for enhanced efficacy and sequential administration of synergistic drug combination in pancreatic cancer
Soni, K. S., Thomas, D., Caffrey, T., Mehla, K., Lei, F., O'Connell, K. A., Sagar, S., Lele, S. M., Hollingsworth, M. A., Radhakrishnan, P. & Bronich, T. K., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 3, p. 894-901 8 p.Research output: Contribution to journal › Article
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme
Xing, X., Kane, D. P., Bulock, C. R., Moore, E. A., Sharma, S., Chabes, A. & Shcherbakova, P. V., Dec 1 2019, In : Nature communications. 10, 1, 374.Research output: Contribution to journal › Article
A simple fluorescent assay for the discovery of protein-protein interaction inhibitors
Al-Mugotir, M., Kolar, C., Vance, K., Kelly, D. L., Natarajan, A. & Borgstahl, G. E. O., Mar 15 2019, In : Analytical Biochemistry. 569, p. 46-52 7 p.Research output: Contribution to journal › Article
Assembly of α-synuclein aggregates on phospholipid bilayers
Lv, Z., Hashemi, M., Banerjee, S., Zagorski, K., Rochet, J. C. & Lyubchenko, Y. L., Sep 2019, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1867, 9, p. 802-812 11 p.Research output: Contribution to journal › Article
Beta 2-microglobulin regulates amyloid precursor-like protein 2 expression and the migration of pancreatic cancer cells
Sliker, B. H., Goetz, B. T., Peters, H. L., Poelaert, B. J., Borgstahl, G. E. O. & Solheim, J. C., Jun 3 2019, In : Cancer Biology and Therapy. 20, 6, p. 931-940 10 p.Research output: Contribution to journal › Article
BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL
Greaves, G., Milani, M., Butterworth, M., Carter, R. J., Byrne, D. P., Eyers, P. A., Luo, X., Cohen, G. M. & Varadarajan, S., Jun 1 2019, In : Cell Death and Differentiation. 26, 6, p. 1037-1047 11 p.Research output: Contribution to journal › Article
BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis
Huang, K., O’Neill, K. L., Li, J., Zhou, W., Han, N., Pang, X., Wu, W., Struble, L., Borgstahl, G., Liu, Z., Zhang, L. & Luo, X., Nov 1 2019, In : Cell Research. 29, 11, p. 942-952 11 p.Research output: Contribution to journal › Article
BORIS Expression in Ovarian Cancer Precursor Cells Alters the CTCF Cistrome and Enhances Invasiveness through GALNT14
Hillman, J. C., Pugacheva, E. M., Barger, C. J., Sribenja, S., Rosario, S., Albahrani, M., Truskinovsky, A. M., Stablewski, A., Liu, S., Loukinov, D. I., Zentner, G. E., Lobanenkov, V. V., Karpf, A. R. & Higgins, M. J., Oct 1 2019, In : Molecular cancer research : MCR. 17, 10, p. 2051-2062 12 p.Research output: Contribution to journal › Article
Breast Cancer Collaborative Registry informs understanding of factors predicting sleep quality
Berger, A. M., Kupzyk, K. A., Djalilova, D. M. & Cowan, K. H., Apr 1 2019, In : Supportive Care in Cancer. 27, 4, p. 1365-1373 9 p.Research output: Contribution to journal › Article
Cancer-Associated Fibroblasts Enhance Survival and Progression of the Aggressive Pancreatic Tumor Via FGF-2 and CXCL8
Awaji, M., Futakuchi, M., Heavican, T., Iqbal, J. & Singh, R. K., Apr 1 2019, In : Cancer Microenvironment. 12, 1, p. 37-46 10 p.Research output: Contribution to journal › Article
Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions
Nowialis, P., Lopusna, K., Opavska, J., Haney, S. L., Abraham, A., Sheng, P., Riva, A., Natarajan, A., Guryanova, O., Simpson, M., Hlady, R., Xie, M. & Opavsky, R., Dec 1 2019, In : Nature communications. 10, 1, 4374.Research output: Contribution to journal › Article
Caveat medicus: Clinician experiences in publishing reports of serious oncology-associated adverse drug reactions
Bennett, C. L., Schooley, B., Taylor, M. A., Witherspoon, B. J., Godwin, A., Vemula, J., Ausdenmoore, H. C., Sartor, O., Tony Yang, Y., Armitage, J. O., Hrushesky, W. J., Restaino, J., Thomsen, H. S., Yarnold, P. R., Young, T., Knopf, K. B. & Chen, B., Jan 1 2019, In : PloS one. 14, 7, e0219521.Research output: Contribution to journal › Article
CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
Kour, S., Rana, S., Contreras, J. I., King, H. M., Robb, C. M., Sonawane, Y. A., Bendjennat, M., Crawford, A. J., Barger, C. J., Kizhake, S., Luo, X., Hollingsworth, M. A. & Natarajan, A., Oct 1 2019, In : Molecular pharmacology. 96, 4, p. 419-429 11 p.Research output: Contribution to journal › Article
Clinical impact of Internet-based tools to guide therapeutic decisions for mantle cell lymphoma
Gopalsamy, S. N., Rosenthal, K. M., Ayers, A. A., Goy, A., Leonard, J. P., Vose, J. M., Obholz, K. L., Armitage, J. O. & Flowers, C. R., Jul 29 2019, In : Leukemia and Lymphoma. 60, 9, p. 2255-2263 9 p.Research output: Contribution to journal › Article
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Bryant, K. L., Stalnecker, C. A., Zeitouni, D., Klomp, J. E., Peng, S., Tikunov, A. P., Gunda, V., Pierobon, M., Waters, A. M., George, S. D., Tomar, G., Papke, B., Hobbs, G. A., Yan, L., Hayes, T. K., Diehl, J. N., Goode, G. D., Chaika, N. V., Wang, Y., Zhang, G. F. & 11 others, , Apr 1 2019, In : Nature Medicine. 25, 4, p. 628-640 13 p.Research output: Contribution to journal › Article
Common genetic variants contribute to incomplete penetrance: evidence from cancer-free BRCA1 mutation carriers
Downs, B., Sherman, S., Cui, J., Kim, Y. C., Snyder, C., Christensen, M., Luo, J., Lynch, H. & Wang, S. M., Jan 2019, In : European Journal of Cancer. 107, p. 68-78 11 p.Research output: Contribution to journal › Article
Comparative Study of Subcutaneous and Orthotopic Mouse Models of Prostate Cancer: Vascular Perfusion, Vasculature Density, Hypoxic Burden and BB2r-Targeting Efficacy
Zhang, W., Fan, W., Rachagani, S., Zhou, Z., Lele, S. M., Batra, S. K. & Garrison, J. C., Jul 31 2019, In : Scientific reports. 9, 1, 1 p.Research output: Contribution to journal › Article
Computer-designed active human butyrylcholinesterase double mutant with a new catalytic triad
Grigorenko, B. L., Novichkova, D. A., Lushchekina, S. V., Zueva, I. V., Schopfer, L. M., Nemukhin, A. V., Varfolomeev, S. D., Lockridge, O. & Masson, P., Jun 1 2019, In : Chemico-Biological Interactions. 306, p. 138-146 9 p.Research output: Contribution to journal › Article
CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI
Hu, W. F., Krieger, K. L., Lagundžin, D., Li, X., Cheung, R. S., Taniguchi, T., Johnson, K. R., Bessho, T., Monteiro, A. N. A. & Woods, N. T., Dec 1 2019, In : Cell Death Discovery. 5, 1, 105.Research output: Contribution to journal › Article
CXCR2: A novel mediator of mammary tumor bone metastasis
Sharma, B., Nannuru, K. C., Saxena, S., Varney, M. L. & Singh, R. K., Mar 2019, In : International journal of molecular sciences. 20, 5, 1237.Research output: Contribution to journal › Article
Cyclin-dependent kinase 1-mediated AMPK phosphorylation regulates chromosome alignment and mitotic progression
Stauffer, S., Zeng, Y., Santos, M., Zhou, J., Chen, Y. & Dong, J., Oct 28 2019, In : Journal of cell science. 132, 20Research output: Contribution to journal › Article
Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity
Yin, L., Zeng, Y., Xiao, Y., Chen, Y., Shen, H. & Dong, J., Jun 1 2019, In : Cell Death and Disease. 10, 6, 385.Research output: Contribution to journal › Article
Delineating the role of FANCA in glucose-stimulated insulin secretion in β cells through its protein interactome
Lagundžin, D., Hu, W. F., Law, H. C. H., Krieger, K. L., Qiao, F., Clement, E. J., Drincic, A. T., Nedić, O., Naldrett, M. J., Alvarez, S. & Woods, N. T., Jan 1 2019, In : PloS one. 14, 8, e0220568.Research output: Contribution to journal › Article
Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu 4 )
Bollinger, S. R., Engers, D. W., Panarese, J. D., West, M., Engers, J. L., Loch, M. T., Rodriguez, A. L., Blobaum, A. L., Jones, C. K., Thompson Gray, A., Conn, P. J., Lindsley, C. W., Niswender, C. M. & Hopkins, C. R., Oct 1 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 342-358 17 p.Research output: Contribution to journal › Article
Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators
Sharma, S., Kozek, K. A., Abney, K. K., Kumar, S., Gautam, N., Alnouti, Y., David Weaver, C. & Hopkins, C. R., Mar 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 6, p. 791-796 6 p.Research output: Contribution to journal › Article
Discovery and Characterization of 2-Nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)- N-(pyridin-4-ylmethyl)anilines as Novel Inhibitors of the Aedes aegypti Kir1 (AeKir1) Channel
Aretz, C. D., Morwitzer, M. J., Sanford, A. G., Hogan, A. M., Portillo, M. V., Kharade, S. V., Kramer, M., McCarthey, J. B., Trigueros, R. R., Piermarini, P. M., Denton, J. S. & Hopkins, C. R., Jun 14 2019, In : ACS infectious diseases. 5, 6, p. 917-931 15 p.Research output: Contribution to journal › Article
Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches to Develop Novel Diuretic Therapeutics
Aretz, C. D., Vadukoot, A. K. & Hopkins, C. R., Oct 10 2019, In : Journal of Medicinal Chemistry. 62, 19, p. 8682-8694 13 p.Research output: Contribution to journal › Article
Discovery of VU2957 (Valiglurax): An mGlu 4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease
Panarese, J. D., Engers, D. W., Wu, Y. J., Bronson, J. J., Macor, J. E., Chun, A., Rodriguez, A. L., Felts, A. S., Engers, J. L., Loch, M. T., Emmitte, K. A., Castelhano, A. L., Kates, M. J., Nader, M. A., Jones, C. K., Blobaum, A. L., Conn, P. J., Niswender, C. M., Hopkins, C. R. & Lindsley, C. W., Mar 14 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 255-260 6 p.Research output: Contribution to journal › Article
DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis
Milani, M., Beckett, A. J., Al-Zebeeby, A., Luo, X., Prior, I. A., Cohen, G. M. & Varadarajan, S., Dec 1 2019, In : Cell Death Discovery. 5, 1, 117.Research output: Contribution to journal › Article
Dual delivery nanoscale device for miR-345 and gemcitabine co-delivery to treat pancreatic cancer
Uz, M., Kalaga, M., Pothuraju, R., Ju, J., Junker, W. M., Batra, S. K., Mallapragada, S. & Rachagani, S., Jan 28 2019, In : Journal of Controlled Release. 294, p. 237-246 10 p.Research output: Contribution to journal › Article
Dual responsive micelles capable of modulating miRNA-34a to combat taxane resistance in prostate cancer
Lin, F., Wen, D., Wang, X. & Mahato, R. I., Feb 2019, In : Biomaterials. 192, p. 95-108 14 p.Research output: Contribution to journal › Article
Effects of center type and socioeconomic factors on early mortality and overall survival of diffuse large B-cell lymphoma
Dhakal, P., Chen, B., Giri, S., Vose, J. M., Armitage, J. O. & Bhatt, V. R., Jun 2019, In : Future Oncology. 15, 18, p. 2113-2124 12 p.Research output: Contribution to journal › Article
Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes, but does not reduce the inhibitory effects of enzalutamide
Metz, E. P., Wilder, P. J., Dong, J., Datta, K. & Rizzino, A., Jan 1 2019, (Accepted/In press) In : Journal of Cellular Physiology.Research output: Contribution to journal › Article
Epigenetic activation of POTE genes in ovarian cancer
Sharma, A., Albahrani, M., Zhang, W., Kufel, C. N., James, S. R., Odunsi, K., Klinkebiel, D. & Karpf, A. R., Feb 1 2019, In : Epigenetics. 14, 2, p. 185-197 13 p.Research output: Contribution to journal › Article
ERK-mediated TIMELESS expression suppresses G2/M arrest in colon cancer cells
Neilsen, B. K., Frodyma, D. E., McCall, J. L., Fisher, K. W. & Lewis, R. E., Jan 2019, In : PloS one. 14, 1, e0209224.Research output: Contribution to journal › Article
Estrogen Metabolism in African-American Women with and without Breast Cancer: A Pilot Study
Zahid, M., Mondal, B., Levan, T. D. & Rogan, E. G., Jan 22 2019, In : Chemical Research in Toxicology. 32, 1, p. 190-194 5 p.Research output: Contribution to journal › Article
Extranodal NK/T-Cell Lymphoma, Nasal Type: Shrouded No More
Lunning, M. A., Oct 1 2019, In : Journal of oncology practice. 15, 10, p. 521-522 2 p.Research output: Contribution to journal › Article
Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments
Lin, S., Huang, C., Gunda, V., Sun, J., Chellappan, S. P., Li, Z., Izumi, V., Fang, B., Koomen, J., Singh, P. K., Hao, J. & Yang, S., Sep 10 2019, In : Cell Reports. 28, 11, p. 2824-2836.e8Research output: Contribution to journal › Article
FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis
Seshacharyulu, P., Rachagani, S., Muniyan, S., Siddiqui, J. A., Cruz, E., Sharma, S., Krishnan, R., Killips, B. J., Sheinin, Y., Lele, S. M., Smith, L. M., Talmon, G. A., Ponnusamy, M. P., Datta, K. & Batra, S. K., Jun 27 2019, In : Oncogene. 38, 26, p. 5265-5280 16 p.Research output: Contribution to journal › Article
Force clamp approach for characterization of nano-assembly in amyloid beta 42 dimer
Maity, S. & Lyubchenko, Y. L., Jul 7 2019, In : Nanoscale. 11, 25, p. 12259-12265 7 p.Research output: Contribution to journal › Article