Eppley Institute for Cancer Research

Research Output 1967 2019

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2019

Evaluating the metabolic alterations in pancreatic cancer

Dasgupta, A., Shukla, S. K., Gunda, V., King, R. J. & Singh, P., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 221-228 8 p. (Methods in Molecular Biology; vol. 1882).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pancreatic Neoplasms
Neoplasms
Metabolic Networks and Pathways
Glutamine
Oxygen Consumption

Molecular and physiological evaluation of pancreatic cancer-induced cachexia

Shukla, S. K., Dasgupta, A., Mulder, S. E. & Singh, P., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 321-333 13 p. (Methods in Molecular Biology; vol. 1882).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cachexia
Pancreatic Neoplasms
Muscles
Fats
Rotarod Performance Test
2018
1 Citation (Scopus)

Assembly of centromere chromatin for characterization by high-speed time-lapse atomic force microscopy

Stumme-Diers, M. P., Banerjee, S., Sun, Z. & Lyubchenko, Y. L., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 225-242 18 p. (Methods in Molecular Biology; vol. 1814).

Research output: Chapter in Book/Report/Conference proceedingChapter

Chromatin Assembly and Disassembly
Centromere
Atomic Force Microscopy
Nucleosomes
Histones

Cardiac toxicity

Yahalom, J. & Lunning, M. A., Nov 16 2018, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 2120-2128 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cardiotoxicity

Diagnosis and treatment of non-hodgkin’s lymphoma of adults

Crockett, D. G., Armitage, J. O. & Vose, J. M., Jan 1 2018, Neoplastic Diseases of the Blood. Springer International Publishing, p. 951-973 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Non-Hodgkin's Lymphoma
Combination Drug Therapy
Immunotherapy
Neoplasms
Lymph Nodes

Evaluating the metabolic impact of hypoxia on pancreatic cancer cells

Murthy, D., Vernucci, E., Goode, G., Abrego, J. & Singh, P., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1742. p. 81-93 13 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pancreatic Neoplasms
NAD
Glutamine
Adenosine Triphosphate
Glucose
3 Citations (Scopus)

Evaluation of macrophage polarization in pancreatic cancer microenvironment under hypoxia

Attri, K. S., Mehla, K. & Singh, P., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1742. p. 265-276 12 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

Tumor Microenvironment
Pancreatic Neoplasms
Macrophages
Hypoxia-Inducible Factor 1
Neoplasms
4 Citations (Scopus)

Hypoxia-induced metabolomic alterations in pancreatic cancer cells

Gunda, V., Kumar, S., Dasgupta, A. & Singh, P., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1742. p. 95-105 11 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabolomics
Hypoxia-Inducible Factor 1
Pancreatic Neoplasms
Tumor Microenvironment
Tandem Mass Spectrometry

Hypoxia-mediated in vivo tumor glucose uptake measurement and analysis

Shukla, S. K., Mulder, S. E. & Singh, P., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1742. p. 107-113 7 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

Glucose
Hypoxia-Inducible Factor 1
Neoplasms
Facilitative Glucose Transport Proteins
Pancreatic Neoplasms
1 Citation (Scopus)

Polymer nanoarray approach for the characterization of biomolecular interactions

Maity, S., Viazovkina, E., Gall, A. & Lyubchenko, Y. L., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 63-74 12 p. (Methods in Molecular Biology; vol. 1814).

Research output: Chapter in Book/Report/Conference proceedingChapter

Polymers
Peptides
Catalytic Domain
Optical Tweezers
Amyloid
2 Citations (Scopus)

Supported lipid bilayers for atomic force microscopy studies

Lv, Z., Banerjee, S., Zagorski, K. & Lyubchenko, Y. L., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 129-143 15 p. (Methods in Molecular Biology; vol. 1814).

Research output: Chapter in Book/Report/Conference proceedingChapter

Atomic Force Microscopy
Lipid Bilayers
Serine
Amyloidogenic Proteins
Phosphorylcholine
1 Citation (Scopus)

Transcriptional profiling using RNA-seq to study hypoxia-mediated gene regulation

Shukla, S. K., King, R. J. & Singh, P., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1742. p. 55-66 12 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

RNA
Genes
Transcription Factors
Gene Expression
Cell Separation
1 Citation (Scopus)

Unfolding thermodynamics of nucleic acids: Determining heat capacity effects using differential scanning calorimetry (DSC)

Carr, C. E., Reiling-Steffensmeier, C., Khutsishvili, I. & Marky, L. A., Jan 1 2018, Differential Scanning Calorimetry: Basics and Applications. Nova Science Publishers, Inc., p. 1-41 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nucleic acids
Differential Scanning Calorimetry
differential scanning calorimetry
Thermodynamics
thermodynamics
2017

Atomic force microscope for topographic studies

Lyubchenko, Y. L., Jan 1 2017, An Introduction to Single Molecule Biophysics. CRC Press, p. 21-78 58 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nobel Prize
Microscopes
microscopes
Inventors
Electromagnetic Fields

Esterases

Lockridge, O., Quinn, D. M. & Radić, Z., Dec 15 2017, Biotransformation. Elsevier Inc., Vol. 10-15. p. 277-307 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Esterases
Acetylcholinesterase
Butyrylcholinesterase
Aryldialkylphosphatase
Carboxylesterase

Magnetic tweezers

Bianco, P. R., Lyubchenko, Y. L. & Sun, Z., Jan 1 2017, An Introduction to Single Molecule Biophysics. CRC Press, p. 115-139 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atomic Force Microscopy
Optical Tweezers
Biophysics
Molecules
Magnetic Fields
2 Citations (Scopus)

Mechanisms of global and region-specific control of mutagenesis

Pavlov, Y. I., Lada, A. G., Grabow, C. & Stepchenkova, E. I., Jan 1 2017, Genetics, Evolution and Radiation: Crossing Borders, The Interdisciplinary Legacy of Nikolay W. Timofeeff-Ressovsky. Springer International Publishing, p. 55-76 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mutagenesis
mutagenesis
mutation
DNA
Genes
1 Citation (Scopus)

Structure and biophysics of CBFβ/ RUNX and its translocation products

Tahirov, T. H. & Bushweller, J., 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 962. p. 21-31 11 p. (Advances in Experimental Medicine and Biology; vol. 962).

Research output: Chapter in Book/Report/Conference proceedingChapter

Core Binding Factors
Biophysics
Transcription Factors
Fusion reactions
Protein Subunits
2016

Ancillary diagnostic opportunities: Harnessing circulating tumor cells, tumor educated platelets, and extracellular vesicles for the early detection of pancreatic cancer

Cruz, E. & Batra, S. K., Jan 1 2016, Gastrointestinal Cancers: Prevention, Detection and Treatment. Nova Science Publishers, Inc., Vol. 2. p. 81-92 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Circulating Neoplastic Cells
Pancreatic Neoplasms
Early Detection of Cancer
Blood Platelets
Neoplasms
4 Citations (Scopus)

Atomic force microscopy imaging and probing of amyloid nanoaggregates

Lyubchenko, Y. L. & Shlyakhtenko, L. S., Feb 24 2016, Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy and Clinical Applications. Pan Stanford Publishing Pte. Ltd., Vol. 1. p. 589-616 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurodegenerative diseases
Medical nanotechnology
Amyloid
Atomic force microscopy
Glycoproteins

Bioinformatics analysis to identify cell adhesion molecules in cancer

Sadanandam, A., Gibb, W. J. & Singh, R. K., Apr 19 2016, Adhesion Molecules. CRC Press, p. 309-325 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Adhesion Molecules
Bioinformatics
Computational Biology
Tumors
Cells
2 Citations (Scopus)

Inhibition of depurinating estrogen-DNA adduct formation in the prevention of breast and other cancers

Cavalieri, E. & Rogan, E. G., Jan 1 2016, Trends in Breast Cancer Prevention. Springer International Publishing, p. 113-145 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

DNA Adducts
Estrogens
Breast Neoplasms
Neoplasms
Breast
1 Citation (Scopus)

Nanoimaging for nanomedicine

Lyubchenko, Y. L., Zhang, Y., Krasnoslobodtsev, A. V. & Rochet, J. C., Feb 24 2016, Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy and Clinical Applications. Pan Stanford Publishing Pte. Ltd., Vol. 1. p. 465-492 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Parkinson disease
Neurodegenerative diseases
Nanomedicine
Medical nanotechnology
Glycoproteins

Novel cancer therapies by molecular targeting distinct growth factor pathways and drug resistance-associated molecules in cancer-and metastasis-initiating cells

Mimeault, M. & Batra, S. K., Apr 19 2016, Role of Cancer Stem Cells in Cancer Biology and Therapy. CRC Press, p. 199-226 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Drug Resistance
Intercellular Signaling Peptides and Proteins
Neoplasm Metastasis
Neoplasms
Therapeutics

Pharmacogenomics of neurodegenerative diseases: Roles in personalized medicines

Evande, R. E., Dutta, R., Tan, C., Grem, J. L. & Mahato, R. I., Jan 1 2016, Neuroimmune Pharmacology. Springer International Publishing, p. 959-970 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Precision Medicine
Pharmacogenetics
Neurodegenerative Diseases
Pharmaceutical Preparations
Genomics
9 Citations (Scopus)

Production of Recombinant Chemokines and Validation of Refolding

Veldkamp, C. T., Koplinski, C. A., Jensen, D. R., Peterson, F. C., Smits, K. M., Smith, B. L., Johnson, S. K., Lettieri, C., Buchholz, W. G., Solheim, J. C. & Volkman, B. F., 2016, Methods in Enzymology. Academic Press Inc., Vol. 570. p. 539-565 27 p. (Methods in Enzymology; vol. 570).

Research output: Chapter in Book/Report/Conference proceedingChapter

Chemokines
Functional analysis
Bioactivity
Proteins
Clinical Trials
2015

BAR Domains and BAR Domain Superfamily Proteins

Sharma, M. & Caplan, S. H., Jan 1 2015, Organizational Cell Biology. Elsevier Inc., Vol. 2. p. 491-502 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Membranes
Organelles
Cell Division
Cell Movement
Actins

Biomarkers of Exposure to Organophosphorus Poisons: A New Motif for Covalent Binding to Tyrosine in Proteins That Have No Active Site Serine. A New Motif for Covalent Binding to Tyrosine in Proteins That Have No Active Site Serine

Lockridge, O., Schopfer, L. M. & Masson, P., Jan 21 2015, Handbook of Toxicology of Chemical Warfare Agents: Second Edition. Elsevier Inc., p. 953-965 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Poisons
Serine
Tyrosine
Catalytic Domain
Biomarkers
1 Citation (Scopus)

Cardiac toxicity

Yahalom, J. & Lunning, M. A., Jan 7 2015, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology: Tenth Edition. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceedingChapter

Cardiotoxicity
1 Citation (Scopus)

Chromatin imaging with time-lapse atomic force microscopy

Lyubchenko, Y. L. & Shlyakhtenko, L. S., Mar 31 2015, Chromatin Protocols: Third Edition. Springer New York, p. 27-42 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Time-Lapse Imaging
Atomic Force Microscopy
Chromatin
Atomic force microscopy
Imaging techniques

Clinical evaluation

Armitage, J. O. & Gisselbrecht, C., Jan 1 2015, Hodgkin Lymphoma: A Comprehensive Overview, Second Edition. Springer International Publishing, p. 95-106 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hodgkin Disease
Lymph Nodes
Superior Vena Cava Syndrome
Clavicle
Sweat

Mouse models of breast cancer

Sakamoto, K., Schmidt, J. W. & Wagner, K. U., Jan 30 2015, Mouse Models of Cancer: Methods and Protocols. Springer New York, p. 47-71 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

breast neoplasms
animal models
Breast Neoplasms
Neoplasms
carcinogenesis

Oxidative metabolism of estrogens in cancer initiation and prevention

Rogan, E. G. & Cavalieri, E., 2015, Oxidative Stress: Diagnostics, Prevention, and Therapy Volume 2. American Chemical Society, Vol. 1200. p. 35-51 17 p. (ACS Symposium Series; vol. 1200).

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabolism
Estrogens
DNA Adducts
Catechol Estrogens
Quinones
5 Citations (Scopus)

Qualitative and quantitative analysis of endocytic recycling

Reineke, J. B., Xie, S., Naslavsky, N. & Caplan, S. H., 2015, Methods in Cell Biology. Academic Press Inc., Vol. 130. p. 139-155 17 p. (Methods in Cell Biology; vol. 130).

Research output: Chapter in Book/Report/Conference proceedingChapter

Endocytosis
Clathrin
Cell Membrane
Intracellular Membranes
Eukaryotic Cells

Tumor microenvironment: Blood vascular system in cancer metastasis

Senapati, S., Singh, R. K. & Batra, S. K., Jan 1 2015, Systems Biology of Cancer. Cambridge University Press, p. 309-322 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tumor Microenvironment
Blood Vessels
Tumors
Blood
Neoplasm Metastasis
2014
4 Citations (Scopus)

Antibody labeling with radioiodine and radiometals

Gupta, S., Batra, S. K. & Jain, M., Jan 1 2014, Drug Delivery System. Humana Press Inc., Vol. 1141. p. 147-157 11 p. (Methods in Molecular Biology; vol. 1141).

Research output: Chapter in Book/Report/Conference proceedingChapter

Antibodies
Radioisotopes
Radioimmunotherapy
Chelating Agents
Biological Assay

Antibody labeling with radioiodine and radiometals

Gupta, S., Batra, S. K. & Jain, M., 2014, Methods in Molecular Biology. Humana Press Inc., Vol. 1141. p. 147-157 11 p. (Methods in Molecular Biology; vol. 1141).

Research output: Chapter in Book/Report/Conference proceedingChapter

Antibodies
Radioisotopes
Radioimmunotherapy
Chelating Agents
Biological Assay

Generation of Conditional Knockout Mice

Sakamoto, K., Gurumurthy, C. B. & Wagner, K. U., 2014, Methods in Molecular Biology. Humana Press Inc., Vol. 1194. p. 21-35 15 p. (Methods in Molecular Biology; vol. 1194).

Research output: Chapter in Book/Report/Conference proceedingChapter

Knockout Mice
Gene Targeting
Organism Cloning
Embryonic Stem Cells
Genes
2 Citations (Scopus)

Interaction of DNA intramolecular structures with their complementary strands: A thermodynamic approach for the control of gene expression

Khutsishvili, I., Johnson, S. E., Reiling, C., Prislan, I., Lee, H. T. & Marky, L. A., Jan 1 2014, Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications. Springer Berlin Heidelberg, p. 367-383 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Thermodynamics
Gene expression
Gene Expression
DNA
Hot Temperature
1 Citation (Scopus)

Pharmacodynamic responses to DNA methyltransferase inhibition

Griffiths, E., Momparler, R. L. & Karpf, A. R., Apr 1 2014, Epigenetic Therapy of Cancer: Preclinical Models and Treatment Approaches. Springer-Verlag Berlin Heidelberg, Vol. 9783642384042. p. 171-188 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Methyltransferases
decitabine
DNA
Azacitidine
Cytotoxins

Primary cutaneous B-cell lymphomas

Rozati, S., Dummer, R., Lunning, M. A., Horwitz, S., Ott, G. & Hsi, E. D., Jan 1 2014, Rare Lymphomas. Springer Berlin Heidelberg, p. 353-364 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

B-Cell Lymphoma
Skin
Lymphoma
Non-Hodgkin's Lymphoma
Pseudolymphoma

Role of PET Scan in Lymphomas

Lunning, M. A. & Armitage, J. O., Jun 20 2014, Cancer Consult: Expertise for Clinical Practice. Wiley Blackwell, p. 389-397 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Positron-Emission Tomography
Lymphoma
Peripheral T-Cell Lymphoma
Hodgkin Disease
Pharmaceutical Preparations
17 Citations (Scopus)

Visualization of DNA and protein-DNA complexes with atomic force microscopy

Lyubchenko, Y. L., Gall, A. A. & Shlyakhtenko, L. S., 2014, Methods in Molecular Biology. Humana Press Inc., Vol. 1117. p. 367-384 18 p. (Methods in Molecular Biology; vol. 1117).

Research output: Chapter in Book/Report/Conference proceedingChapter

Atomic Force Microscopy
DNA
Proteins
Nucleoproteins
Divalent Cations
2013
1 Citation (Scopus)

AFM visualization of protein-DNA interactions

Lyubchenko, Y. L., Jan 1 2013, Single-molecule Studies of Proteins. Springer New York, p. 97-117 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atomic Force Microscopy
Atomic force microscopy
Visualization
DNA
Proteins
1 Citation (Scopus)

Analysis of tumor-associated mucin glycotopes by western transfer methods

Gnanapragassam, V. S., Jain, M. & Batra, S. K., Jan 1 2013, Pancreatic Cancer: Methods and Protocols. Humana Press Inc., p. 331-340 10 p. (Methods in Molecular Biology; vol. 980).

Research output: Chapter in Book/Report/Conference proceedingChapter

Mucins
Polysaccharides
Neoplasms
Glycosylation
Lectins

Atomic force microscopy of RNA: Imaging and beyond

Schön, P. M., Shlyakhtenko, L. S. & Lyubchenko, Y. L., Jan 1 2013, RNA Nanotechnology and Therapeutics. CRC Press, p. 237-261 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atomic Force Microscopy
Atomic force microscopy
RNA
Imaging techniques
Biological systems
2 Citations (Scopus)

Biomedical Applications of "Click"-Modified Cyclodextrins

Jia, Z., Singh, R. K. & Wang, D., Feb 6 2013, Click Chemistry in Glycoscience: New Developments and Strategies. John Wiley and Sons, p. 271-292 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cyclodextrins
Cycloaddition
Cycloaddition Reaction
Click Chemistry
Alkynes

Diagnosis and treatment of non-Hodgkin's lymphoma of adults

Faber, E. A., Vose, J. M., Armitage, J. O. & Bierman, P. J., Nov 1 2013, Neoplastic Diseases of the Blood. Springer New York, p. 1027-1047 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Non-Hodgkin's Lymphoma
Incidence
Hodgkin Disease
Neoplasms
Occupational Exposure
1 Citation (Scopus)

Gene therapy

Wu, H. & Mahato, R. I., Jan 1 2013, Pharmaceutical Biotechnology: Fundamentals and Applications, Fourth Edition. Springer New York, p. 477-507 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genetic Therapy
Motor Neuron Disease
Proteins
Hemophilia A
Human Body

Gene Therapy in Oncology

Talmadge, J. E. & Cowan, K. H., Oct 22 2013, Abeloff's Clinical Oncology: Fifth Edition. Elsevier Inc., p. 493-507.e4

Research output: Chapter in Book/Report/Conference proceedingChapter

Genetic Therapy