Research Output 1979 2019

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Review article
2019

Cancer-associated fibroblasts’ functional heterogeneity in pancreatic ductal adenocarcinoma

Awaji, M. & Singh, R. K., Mar 1 2019, In : Cancers. 11, 3, 290.

Research output: Contribution to journalReview article

Open Access
Adenocarcinoma
Extracellular Matrix
Inflammation
Neoplasms
Myofibroblasts

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases

Mishra, S., Verma, S. S., Rai, V., Awasthee, N., Chava, S., Hui, K. M., Kumar, A. P., Challagundla, K. B., Sethi, G. & Gupta, S. C., Jan 1 2019, In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalReview article

Long Noncoding RNA
Phytochemicals
Chronic Disease
Neoplasms
Berberine

Managing Squamous Cell Esophageal Cancer

Batra, R., Malhotra, G. K., Singh, S. & Are, C., Jan 1 2019, In : Surgical Clinics of North America.

Research output: Contribution to journalReview article

Squamous Cell Neoplasms
Esophageal Neoplasms

Novel therapies hijack the blood-brain barrier to eradicate glioblastoma cancer stem cells

Vengoji, R., Palanimuthu Ponnusamy, M., Rachagani, S., Mahapatra, S., Batra, S. K., Shonka, N. A. & Macha, M. A., Mar 12 2019, In : Carcinogenesis. 40, 1, p. 2-14 13 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Glioblastoma
Blood-Brain Barrier
temozolomide
Radiotherapy

Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review

Zenere, G., Olwenyi, O. A., Byrareddy, S. N. & Braun, S. E., Jan 1 2019, In : Drug Discovery Today.

Research output: Contribution to journalReview article

Antigen Receptors
Natural Killer Cells
Immunotherapy
HIV
HIV Infections

Reactive Oxygen Species Drive Epigenetic Changes in Radiation-Induced Fibrosis

Shrishrimal, S., Kosmacek, E. A. & Deegan, R. E., Jan 1 2019, In : Oxidative medicine and cellular longevity. 2019, 1 p.

Research output: Contribution to journalReview article

Open Access
Radiation Pneumonitis
Epigenomics
Reactive Oxygen Species
Radiation
Myofibroblasts

Relaxin and fibrosis: Emerging targets, challenges, and future directions

Kanai, A. J., Konieczko, E. M., Bennett, R. G., Samuel, C. S. & Royce, S. G., May 1 2019, In : Molecular and Cellular Endocrinology. 487, p. 66-74 9 p.

Research output: Contribution to journalReview article

Relaxin
Fibrosis
Extracellular Matrix
Tissue
Peptide Receptors

Tumor-stromal crosstalk in pancreatic cancer and tissue fibrosis

Thomas, D. & Radhakrishnan, P., Jan 21 2019, In : Molecular Cancer. 18, 1, 1 p.

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Fibrosis
Drug Resistance
Neoplasms
Adenocarcinoma
2 Citations (Scopus)

Unraveling the journey of cancer stem cells from origin to metastasis

Nimmakayala, R. K., Batra, S. K. & Palanimuthu Ponnusamy, M., Jan 1 2019, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1871, 1, p. 50-63 14 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Neoplasm Metastasis
Neoplasms
Population
Horizontal Gene Transfer
2018
Enoxaparin
Low Molecular Weight Heparin
Sulfates
Mass spectrometry
Mass Spectrometry
10 Citations (Scopus)

A review of the catalytic mechanism of human manganese superoxide dismutase

Azadmanesh, J. & Borgstahl, G. E., Feb 1 2018, In : Antioxidants. 7, 2, 25.

Research output: Contribution to journalReview article

Superoxide Dismutase
Reactive Oxygen Species
Neurodegenerative diseases
Lymphatic System
Mutation
8 Citations (Scopus)

Emerging therapeutic potential of graviola and its constituents in cancers

Qazi, A. K., Siddiqui, J. A., Jahan, R., Chaudhary, S., Walker, L. A., Sayed, Z., Jones, D. T., Batra, S. K. & Macha, M. A., Apr 5 2018, In : Carcinogenesis. 39, 4, p. 522-533 12 p.

Research output: Contribution to journalReview article

Annona
Biological Products
Neoplasms
Acetogenins
Annonaceae
2 Citations (Scopus)

Epigenetic modifications of human placenta associated with preterm birth: a systematic review

Toure, D. M., ElRayes, W., Barnes-Josiah, D., Hartman, T., Klinkebiel, D. L. & Baccaglini, L., Feb 16 2018, In : Journal of Maternal-Fetal and Neonatal Medicine. 31, 4, p. 530-541 12 p.

Research output: Contribution to journalReview article

Premature Birth
Epigenomics
Placenta
Infant Mortality
Pregnancy Outcome

ErbB-2 signaling in advanced prostate cancer progression and potential therapy

Miller, D. R., Ingersoll, M. A. & Lin, M-F., Jan 1 2018, In : Endocrine-Related Cancer. 26, 4, p. R195-R209

Research output: Contribution to journalReview article

Prostatic Neoplasms
Castration
Therapeutics
Phosphorylation
MicroRNAs
4 Citations (Scopus)

Glycosylation of Cancer Stem Cells: Function in Stemness, Tumorigenesis, and Metastasis

Barkeer, S., Chugh, S., Batra, S. K. & Palanimuthu Ponnusamy, M., Aug 1 2018, In : Neoplasia (United States). 20, 8, p. 813-825 13 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Glycosylation
Carcinogenesis
Neoplasm Metastasis
Neoplasms
1 Citation (Scopus)

Hunting for transcription factors: STAT3 decoy in non-small cell lung cancer

Carmicheal, J., Kaur, S., Batra, S. K. & Ganti, A. K. P., Sep 1 2018, In : Translational Lung Cancer Research. 7, p. S254-S257

Research output: Contribution to journalReview article

STAT3 Transcription Factor
Non-Small Cell Lung Carcinoma
2 Citations (Scopus)
Lipids
Neoplasms
Obesity
Unsaturated Fatty Acids
Inflammation
2 Citations (Scopus)

Liver as a target of human immunodeficiency virus infection

Ganesan, M., Poluektova, L. Y., Kharbanda, K. & Osna, N. A., Nov 14 2018, In : World Journal of Gastroenterology. 24, 42, p. 4728-4737 10 p.

Research output: Contribution to journalReview article

Virus Diseases
HIV
Liver
Alcohols
Wounds and Injuries
2 Citations (Scopus)

MUC16 as a novel target for cancer therapy

Aithal, A., Rauth, S., Kshirsagar, P., Shah, A., Lakshmanan, I., Junker, W. M., Jain, M., Palanimuthu Ponnusamy, M. & Batra, S. K., Aug 3 2018, In : Expert Opinion on Therapeutic Targets. 22, 8, p. 675-686 12 p.

Research output: Contribution to journalReview article

Physiology
Epitopes
Neoplasms
Antibodies
Expert Testimony
6 Citations (Scopus)

Natural products: A hope for glioblastoma patients

Vengoji, R., Macha, M. A., Batra, S. K. & Shonka, N. A., Apr 24 2018, In : Oncotarget. 9, 31, p. 22199-22224 26 p.

Research output: Contribution to journalReview article

temozolomide
Glioblastoma
Biological Products
Neoplastic Stem Cells
Blood-Brain Barrier
2 Citations (Scopus)

Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in cancer therapy

Bishnoi, S., Tiwari, R., Gupta, S., Byrareddy, S. N. & Nayak, D., Feb 23 2018, In : Viruses. 10, 2, 90.

Research output: Contribution to journalReview article

Vesicular Stomatitis
Viruses
Oncolytic Virotherapy
Neoplasms
Therapeutics
1 Citation (Scopus)

Pancreatic cancer associated with obesity and diabetes: An alternative approach for its targeting

Pothuraju, R., Rachagani, S., Junker, W. M., Chaudhary, S., Viswanathan, S., Kaur, S. & Batra, S. K., Dec 19 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 319.

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Obesity
Type 2 Diabetes Mellitus
Adipokines
Metabolic Diseases
2 Citations (Scopus)

PD2/PAF1 at the crossroads of the cancer network

Karmakar, S., Dey, P., Vaz, A. P., Bhaumik, S. R., Palanimuthu Ponnusamy, M. & Batra, S. K., Jan 15 2018, In : Cancer Research. 78, 2, p. 313-319 7 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Pancreatic Neoplasms
Histone Code
cdc Genes
RNA Polymerase II
3 Citations (Scopus)

Phosphoinositide 3-kinase signaling pathway in pancreatic ductal adenocarcinoma progression, pathogenesis, and therapeutics

Murthy, D., Attri, K. S. & Singh, P., Apr 4 2018, In : Frontiers in Physiology. 9, APR, 335.

Research output: Contribution to journalReview article

1-Phosphatidylinositol 4-Kinase
Adenocarcinoma
Therapeutics
Neoplasms
Mutation
9 Citations (Scopus)

Protein–protein interactions with connexin 43: Regulation and function

Sorgen, P. L., Trease, A. J., Spagnol, G., Delmar, M. & Nielsen, M. S., May 10 2018, In : International Journal of Molecular Sciences. 19, 5, 1428.

Research output: Contribution to journalReview article

Connexin 43
Connexins
Gap Junctions
Proteins
proteins

Ramifications of secreted mucin MUC5AC in malignant journey: A holistic view

Krishn, S. R., Ganguly, K., Kaur, S. & Batra, S. K., Jan 1 2018, In : Carcinogenesis. 39, 5, p. 633-651 19 p.

Research output: Contribution to journalReview article

Mucins
Glycosylation
Gels
Epithelial Cells
Pathology
5 Citations (Scopus)

The enigmatic endosome - Sorting the ins and outs of endocytic trafficking

Naslavsky, N. & Caplan, S. H., Jul 1 2018, In : Journal of Cell Science. 131, 13, jcs216499.

Research output: Contribution to journalReview article

Endosomes
Organelles
Cell Membrane
Recycling
Endocytosis
2017
11 Citations (Scopus)

Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage

Neuman, M. G., French, S. W., Zakhari, S., Malnick, S., Seitz, H. K., Cohen, L. B., Salaspuro, M., Voinea-Griffin, A., Barasch, A., Kirpich, I. A., Thomes, P. G., Schrum, L. W., Donohue, T., Kharbanda, K., Cruz, M. & Opris, M., Feb 1 2017, In : Experimental and Molecular Pathology. 102, 1, p. 162-180 19 p.

Research output: Contribution to journalReview article

Microbiota
Life Style
Liver
Alcohols
Liver Diseases
5 Citations (Scopus)

Alcoholic Liver Disease: Pathogenesis and Current Management

Osna, N. A., Donohue, T. & Kharbanda, K., Jan 1 2017, In : Alcohol research : current reviews. 38, 2, p. 147-161 15 p.

Research output: Contribution to journalReview article

Alcoholic Liver Diseases
Fibrosis
Drinking
Liver
Alcohol Drinking
3 Citations (Scopus)

Bifunctional enzyme JMJD6 contributes to multiple disease pathogenesis: New twist on the old story

Vangimalla, S. S., Ganesan, M., Kharbanda, K. & Osna, N. A., Jun 1 2017, In : Biomolecules. 7, 2, 41.

Research output: Contribution to journalReview article

Enzymes
Proteins
Carcinogenesis
2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine
Oxygenases
8 Citations (Scopus)

Biological determinants of radioresistance and their remediation in pancreatic cancer

Seshacharyulu, P., Baine, M. J., Souchek, J. J., Menning, M., Kaur, S., Yan, Y., Ouellette, M. M., Jain, M., Lin, C. & Batra, S. K., Aug 1 2017, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1868, 1, p. 69-92 24 p.

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Radiotherapy
Radiation
Tumor Microenvironment
Neoplastic Stem Cells
11 Citations (Scopus)

Claudin proteins, outside-in signaling, and carcinogenesis

Singh, A. B., Uppada, S. B. & Dhawan, P., Jan 1 2017, In : Pflugers Archiv European Journal of Physiology. 469, 1, p. 69-75 7 p.

Research output: Contribution to journalReview article

Claudins
Cell adhesion
Cell signaling
Carcinogenesis
Tight Junctions
7 Citations (Scopus)

Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

Lewis, R. E., Frodyma, D., Neilsen, B., Costanzo-Garvey, D. & Fisher, K., 2017, In : F1000Research. 6, 1621.

Research output: Contribution to journalReview article

Scaffolds
Mitogen-Activated Protein Kinase Kinases
Energy balance
MAP Kinase Kinase Kinases
Phosphotransferases
15 Citations (Scopus)

Extracellular superoxide dismutase and its role in cancer

Griess, B., Tom, E., Domann, F. & Teoh-Fitzgerald, M. LT., Nov 1 2017, In : Free Radical Biology and Medicine. 112, p. 464-479 16 p.

Research output: Contribution to journalReview article

Superoxide Dismutase
Reactive Oxygen Species
Tumors
Deregulation
Neoplasms
3 Citations (Scopus)

Genetic variants of mucins: Unexplored conundrum

Kumar, S., Cruz, E., Joshi, S., Patel, A., Jahan, R., KBatra, S. & Jain, M., Jul 1 2017, In : Carcinogenesis. 38, 7, p. 671-679 9 p., bgw120.

Research output: Contribution to journalReview article

Mucins
Neoplasms
Genes
Alternative Splicing
Inflammation
15 Citations (Scopus)

Gut permeability and mucosal inflammation: Bad, good or context dependent

Ahmad, R., Sorrell, M. F., Batra, S. K., Dhawan, P. & Singh, A. B., Mar 1 2017, In : Mucosal Immunology. 10, 2, p. 307-317 11 p.

Research output: Contribution to journalReview article

Permeability
Inflammation
Colitis
Proteins
Homeostasis
1 Citation (Scopus)

Into the linker's DENN: A tyrosine's control of autophagy

Caplan, S. H., Apr 28 2017, In : Journal of Biological Chemistry. 292, 17, p. 7283-7284 2 p.

Research output: Contribution to journalReview article

Guanine Nucleotide Exchange Factors
Phosphorylation
Autophagy
GTP-Binding Proteins
Tyrosine
6 Citations (Scopus)

KSR as a therapeutic target for Ras-dependent cancers

Neilsen, B. K., Frodyma, D. E., Lewis, R. E. & Fisher, K. W., May 4 2017, In : Expert Opinion on Therapeutic Targets. 21, 5, p. 499-509 11 p.

Research output: Contribution to journalReview article

Neoplasms
Therapeutics
ras Proteins
Dimerization
Expert Testimony
9 Citations (Scopus)

MicroRNAs are important regulators of drug resistance in colorectal cancer

Zhang, Y. & Wang, J., Jul 26 2017, In : Biological Chemistry. 398, 8, p. 929-938 10 p.

Research output: Contribution to journalReview article

MicroRNAs
Drug Resistance
Colorectal Neoplasms
Oncology
Pharmaceutical Preparations
12 Citations (Scopus)

MUC4 mucin- a therapeutic target for pancreatic ductal adenocarcinoma

Gautam, S. K., Kumar, S., Cannon, A., Hall, B., Bhatia, R., Nasser, M. W., Mahapatra, S., Batra, S. K. & Jain, M., Jul 3 2017, In : Expert Opinion on Therapeutic Targets. 21, 7, p. 657-669 13 p.

Research output: Contribution to journalReview article

Mucins
Tumors
Adenocarcinoma
Immune system
Pancreatic Neoplasms
11 Citations (Scopus)

Multifaceted role of neuropilins in the immune system: Potential targets for immunotherapy

Roy, S., Bag, A. K., Singh, R. K., Talmadge, J. E., Batra, S. K. & Datta, K., Oct 10 2017, In : Frontiers in Immunology. 8, OCT, 1228.

Research output: Contribution to journalReview article

Neuropilins
Neuropilin-2
Neuropilin-1
Immunotherapy
Immune System
8 Citations (Scopus)

Novel anti-fibrotic therapies

McVicker, B. L. & Bennett, R. G., May 31 2017, In : Frontiers in Pharmacology. 8, MAY, 318.

Research output: Contribution to journalReview article

Relaxin
Fibrosis
MicroRNAs
Cardiovascular Diseases
Bone Morphogenetic Protein 7
2 Citations (Scopus)

Racial disparity in metabolic regulation of cancer

Attri, K. S., Murthy, D. & Singh, P., Mar 1 2017, In : Frontiers in bioscience (Landmark edition). 22, p. 1221-1246 26 p.

Research output: Contribution to journalReview article

Genes
Neoplasms
Tumors
Mutation
Cells
1 Citation (Scopus)

Role of early growth response-1 in the development of alcohol-induced steatosis

Thomes, P. G. & Donohue, T., Aug 1 2017, In : Current Molecular Pharmacology. 10, 3, p. 179-185 7 p.

Research output: Contribution to journalReview article

Alcohols
Growth
Liver
Alcoholic Liver Diseases
Fatty Liver
1 Citation (Scopus)

Structure, function and metabolism of hepatic and adipose tissue lipid droplets: Implications in alcoholic liver disease

Natarajan, S. K., Rasineni, K., Ganesan, M., Feng, D., McVicker, B. L., McNiven, M. A., Osna, N. A., Mott, J. L., Casey, C. A. & Kharbanda, K., Aug 1 2017, In : Current Molecular Pharmacology. 10, 3, p. 237-248 12 p.

Research output: Contribution to journalReview article

Alcoholic Liver Diseases
Adipose Tissue
Liver
Lipids
Virus Assembly
12 Citations (Scopus)

Surface-enhanced raman scattering-based immunoassay technologies for detection of disease biomarkers

Smolsky, J., Kaur, S., Hayashi, C., Batra, S. K. & Krasnoslobodtsev, A. V., Jan 12 2017, In : Biosensors. 7, 1, 7.

Research output: Contribution to journalReview article

Raman Spectrum Analysis
Biomarkers
Immunoassay
Raman scattering
Technology
34 Citations (Scopus)

The dark side of SOX2: Cancer - A comprehensive overview

Wuebben, E. L. & Rizzino, A. A., 2017, In : Oncotarget. 8, 27, p. 44917-44943 27 p.

Research output: Contribution to journalReview article

Neoplasms
SOXB1 Transcription Factors
Long Noncoding RNA
Post Translational Protein Processing
Growth
2016
12 Citations (Scopus)

Functional consequences of differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream effects on signaling)

Hanson, R. L. & Hollingsworth, M. A., Sep 1 2016, In : Biomolecules. 6, 3, 34.

Research output: Contribution to journalReview article

Glycosylation
Mucins
Polysaccharides
Cell signaling
Post Translational Protein Processing
13 Citations (Scopus)

Image-guided tumor surgery: will there be a role for fluorescent nanoparticles?

Hill, T. K. & Mohs, A. M., Jul 1 2016, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 8, 4, p. 498-511 14 p.

Research output: Contribution to journalReview article

Computer-Assisted Surgery
Nanoparticles
Surgery
Tumors
Neoplasms
15 Citations (Scopus)

Potential of CXCR4/CXCL12 Chemokine Axis in Cancer Drug Delivery

Wang, Y., Xie, Y. & Oupicky, D., Feb 1 2016, In : Current Pharmacology Reports. 2, 1

Research output: Contribution to journalReview article

Chemokine CXCL12
Drug Delivery Systems
Drug delivery
CXCR4 Receptors
Chemokine Receptors