Research Output

2020

A comparative analysis of survival and funding discrepancies in cancers with high mortality

Hall, B. R., Cannon, A., Atri, P., Wichman, C. S., Smith, L. M., Kumar, S., Batra, S. K., Wang, H., Ganti, A. K., Sasson, A. R. & Are, C., Feb 1 2020, In : Annals of surgery. 271, 2, p. 296-302 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Advances in cancer cachexia: Intersection between affected organs, mediators, and pharmacological interventions

Siddiqui, J. A., Pothuraju, R., Jain, M., Batra, S. K. & Nasser, M. W., Apr 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 2, 188359.

Research output: Contribution to journalReview article

A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study

Abdul-Rida, N. A., Farhan, A. M., Al-Masoudi, N. A., Saeed, B. A., Miller, D. & Lin, M. F., Jan 1 2020, (Accepted/In press) In : Molecular Diversity.

Research output: Contribution to journalArticle

A phase I study of weekly doxorubicin and oral topotecan for patients with relapsed or refractory small cell lung cancer (SCLC): A Fred and Pamela Buffet Cancer Center Clinical Trials Network study

Ernani, V., Jahan, R., Smith, L. M., Marr, A. S., Kimbrough, S. E., Kos, M. E., Tijerina, J., Pivovar, S., Lakshmanan, I., Ketcham, M., Rauth, S., Mallya, K., Nasser, M. W., Jain, M., Kessinger, A., Batra, S. K. & Ganti, A. K., 2020, In : Cancer Treatment and Research Communications. 22, 100162.

Research output: Contribution to journalArticle

Open Access

A systematic review and meta-analysis of predictors of recurrence in patients with Solid Pseudopapillary Tumors of the Pancreas

Yepuri, N., Naous, R., Meier, A. H., Cooney, R. N., Kittur, D., Are, C., Jain, A. & Dhir, M., Jan 2020, In : HPB. 22, 1, p. 12-19 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

A TFAP2C gene signature is predictive of outcome in HER2-positive breast cancer

Wu, V. T., Kiriazov, B., Koch, K. E., Gu, V. W., Beck, A. C., Borcherding, N., Li, T., Addo, P., Wehrspan, Z. J., Zhang, W., Braun, T. A., Brown, B. J., Band, V., Band, H., Kulak, M. V. & Weigel, R. J., Jan 1 2020, In : Molecular Cancer Research. 18, 1, p. 46-56 11 p.

Research output: Contribution to journalArticle

Characterizing pathological imperfections in macromolecular crystals: lattice disorders and modulations

Lovelace, J. J. & Borgstahl, G. E. O., Jan 2 2020, In : Crystallography Reviews. 26, 1, p. 3-50 48 p.

Research output: Contribution to journalReview article

Claudin-1, a double-edged sword in cancer

Bhat, A. A., Syed, N., Therachiyil, L., Nisar, S., Hashem, S., Macha, M. A., Yadav, S. K., Krishnankutty, R., Muralitharan, S., Al-Naemi, H., Bagga, P., Reddy, R., Dhawan, P., Akobeng, A., Uddin, S., Frenneaux, M. P., El-Rifai, W. & Haris, M., Jan 2 2020, In : International journal of molecular sciences. 21, 2, 569.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Curcumin use in ulcerative colitis: Is it ready for prime time? A systematic review and meta-analysis of clinical trials

Chandan, S., Mohan, B. P., Chandan, O. C., Ahmad, R., Challa, A., Tummala, H., Singh, S., Dhawan, P., Ponnada, S., Singh, A. B. & Adler, D. G., Jan 1 2020, In : Annals of Gastroenterology. 33, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cyclin-dependent kinase 1-mediated phosphorylation of protein kinase N1 promotes anchorage-independent growth and migration

Zeng, R., Wang, Z., Li, X., Chen, Y., Yang, S. & Dong, J., May 2020, In : Cellular Signalling. 69, 109546.

Research output: Contribution to journalArticle

Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain

Zhang, Y., Lu, P., Liang, F., Liufu, N., Dong, Y., Zheng, J. C. & Xie, Z., Feb 11 2020, In : Frontiers in Cell and Developmental Biology. 7, 396.

Research output: Contribution to journalArticle

Open Access

Differentiating Peripherally-Located Small Cell Lung Cancer From Non-small Cell Lung Cancer Using a CT Radiomic Approach

Chen, B. T., Chen, Z., Ye, N., Mambetsariev, I., Fricke, J., Daniel, E., Wang, G., Wong, C. W., Rockne, R. C., Colen, R. R., Nasser, M. W., Batra, S. K., Holodny, A. I., Sampath, S. & Salgia, R., Apr 22 2020, In : Frontiers in Oncology. 10, 593.

Research output: Contribution to journalArticle

Open Access

Direct and indirect quantification of phosphate metabolites of nucleoside analogs in biological samples

Gautam, N., Alamoudi, J. A., Kumar, S. & Alnouti, Y., Jan 30 2020, In : Journal of Pharmaceutical and Biomedical Analysis. 178, 112902.

Research output: Contribution to journalReview article

Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines

Mirzapoiazova, T., Pozhitkov, A., Nam, A., Mambetsariev, I., Nelson, M. S., Tan, Y. H. C., Zhang, K., Raz, D., Singhal, S., Nasser, M. W., Kulkarni, P., Batra, S. K., Sattler, M. & Salgia, R., Jul 2020, In : International journal of oncology. 57, 1, p. 80-86 7 p.

Research output: Contribution to journalArticle

EHD1 and RUSC2 control basal epidermal growth factor receptor cell surface expression and recycling

Tom, E. C., Mushtaq, I., Mohapatra, B. C., Luan, H., Bhat, A. M., Zutshi, N., Chakraborty, S., Islam, N., Arya, P., Bielecki, T. A., Iseka, F. M., Bhattacharyya, S., Cypher, L. R., Goetz, B. T., Negi, S. K., Storck, M. D., Rana, S., Barnekow, A., Singh, P. K., Ying, G. & 4 others, Guda, C., Natarajan, A., Band, V. & Banda, H., Apr 1 2020, In : Molecular and cellular biology. 40, 7, e00434.

Research output: Contribution to journalArticle

1 Scopus citations

Elevating pancreatic cystic lesion stratification: Current and future pancreatic cancer biomarker(s)

Carmicheal, J., Patel, A., Dalal, V., Atri, P., Dhaliwal, A. S., Wittel, U. A., Malafa, M. P., Talmon, G., Swanson, B. J., Singh, S., Jain, M., Kaur, S. & Batra, S. K., Jan 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 1, 188318.

Research output: Contribution to journalReview article

Endocytic membrane trafficking in the control of centrosome function

Naslavsky, N. & Caplan, S., Jan 1 2020, (Accepted/In press) In : Current Opinion in Cell Biology.

Research output: Contribution to journalReview article

Endosomolytic and Tumor-Penetrating Mesoporous Silica Nanoparticles for siRNA/miRNA Combination Cancer Therapy

Wang, Y., Xie, Y., Kilchrist, K. V., Li, J., Duvall, C. L. & Oupický, D., Jan 29 2020, In : ACS Applied Materials and Interfaces. 12, 4, p. 4308-4322 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access

Fluorescent Sensor Arrays Can Predict and Quantify the Composition of Multicomponent Bacterial Samples

Svechkarev, D., Sadykov, M. R., Houser, L. J., Bayles, K. W. & Mohs, A. M., Jan 15 2020, In : Frontiers in Chemistry. 7, 916.

Research output: Contribution to journalArticle

Open Access

Ghrelin regulates adipose tissue metabolism: Role in hepatic steatosis

Rasineni, K., Kubik, J. L., Knight, K. L., Hall, L., Casey, C. A. & Kharbanda, K. K., May 1 2020, In : Chemico-Biological Interactions. 322, 109059.

Research output: Contribution to journalArticle

1 Scopus citations

Glutaminase 1 Regulates Neuroinflammation After Cerebral Ischemia Through Enhancing Microglial Activation and Pro-Inflammatory Exosome Release

Gao, G., Li, C., Zhu, J., Wang, Y., Huang, Y., Zhao, S., Sheng, S., Song, Y., Ji, C., Li, C., Yang, X., Ye, L., Qi, X., Zhang, Y., Xia, X. & Zheng, J. C., Feb 7 2020, In : Frontiers in immunology. 11, 161.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

High-throughput identification of protein functional similarities using a gene-expression-based siRNA screen

Neilsen, B. K., Kelly, D. L., Chakraborty, B., Kim, H. S., White, M. A., Lewis, R. E. & Fisher, K. W., Dec 1 2020, In : Scientific Data. 7, 1, 27.

Research output: Contribution to journalArticle

Open Access

HLA-B influences integrin beta-1 expression and pancreatic cancer cell migration

Sliker, B. H., Goetz, B. T., Barnes, R., King, H., Maurer, H. C., Olive, K. P. & Solheim, J. C., May 15 2020, In : Experimental Cell Research. 390, 2, 111960.

Research output: Contribution to journalArticle

Identification of Fusion Transcripts from Unaligned RNA-Seq Reads Using ChimeRScope

Vellichirammal, N. N., Albahrani, A., Li, Y. & Guda, C., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 13-25 13 p. (Methods in Molecular Biology; vol. 2079).

Research output: Chapter in Book/Report/Conference proceedingChapter

IL-17–CXC Chemokine Receptor 2 Axis Facilitates Breast Cancer Progression by Up-Regulating Neutrophil Recruitment

Wu, L., Awaji, M., Saxena, S., Varney, M. L., Sharma, B. & Singh, R. K., Jan 2020, In : American Journal of Pathology. 190, 1, p. 222-233 12 p.

Research output: Contribution to journalArticle

Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer

Gupta, S., Prajapati, A., Gulati, M., Gautam, S. K., Kumar, S., Dalal, V., Talmon, G. A., Rachagani, S. & Jain, M., Feb 2020, In : Neoplasia (United States). 22, 2, p. 98-110 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Linking NRP2 With EMT and Chemoradioresistance in Bladder Cancer

Schulz, A., Gorodetska, I., Behrendt, R., Fuessel, S., Erdmann, K., Foerster, S., Datta, K., Mayr, T., Dubrovska, A. & Muders, M. H., Jan 21 2020, In : Frontiers in Oncology. 9, 1461.

Research output: Contribution to journalArticle

Open Access

Long non-coding RNAs and nuclear factor-κB crosstalk in cancer and other human diseases

Gupta, S. C., Awasthee, N., Rai, V., Chava, S., Gunda, V. & Challagundla, K. B., Jan 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 1, 188316.

Research output: Contribution to journalReview article

4 Scopus citations

Macrophages potentiate STAT3 signaling in skeletal muscles and regulate pancreatic cancer cachexia

Shukla, S. K., Markov, S. D., Attri, K. S., Vernucci, E., King, R. J., Dasgupta, A., Grandgenett, P. M., Hollingsworth, M. A., Singh, P. K., Yu, F. & Mehla, K., Aug 1 2020, In : Cancer Letters. 484, p. 29-39 11 p.

Research output: Contribution to journalArticle

Maturation of Lipophagic Organelles in Hepatocytes Is Dependent Upon a Rab10/Dynamin-2 Complex

Li, Z., Weller, S. G., Drizyte-Miller, K., Chen, J., Krueger, E. W., Mehall, B., Casey, C. A., Cao, H. & McNiven, M. A., Jan 1 2020, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Mechanisms, biomarkers and targets for therapy in alcohol-associated liver injury: From Genetics to nutrition: Summary of the ISBRA 2018 symposium

Kirpich, I. A., Warner, D. R., Feng, W., Joshi-Barve, S., McClain, C. J., Seth, D., Zhong, W., Zhou, Z., Osna, N. A. & Kharbanda, K. K., Mar 2020, In : Alcohol. 83, p. 105-114 10 p.

Research output: Contribution to journalReview article

1 Scopus citations

Mechanistic and functional shades of mucins and associated glycans in colon cancer

Pothuraju, R., Krishn, S. R., Gautam, S. K., Pai, P., Ganguly, K., Chaudhary, S., Rachagani, S., Kaur, S. & Batra, S. K., Mar 2020, In : Cancers. 12, 3, 649.

Research output: Contribution to journalReview article

Open Access

Metabolic alterations in pancreatic cancer progression

Vernucci, E., Abrego, J., Gunda, V., Shukla, S. K., Dasgupta, A., Rai, V., Chaika, N., Buettner, K., Illies, A., Yu, F., Lazenby, A. J., Swanson, B. J. & Singh, P. K., Jan 2020, In : Cancers. 12, 1, 2.

Research output: Contribution to journalArticle

Open Access

Metabolic subtyping for novel personalized therapies against pancreatic cancer

Mehla, K. & Singh, P. K., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 6-8 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

MicroRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy

Kanchan, R. K., Siddiqui, J. A., Mahapatra, S., Batra, S. K. & Nasser, M. W., Feb 15 2020, In : Molecular cancer. 19, 1, 29.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

MiR-1253 exerts tumor-suppressive effects in medulloblastoma via inhibition of CDK6 and CD276 (B7-H3)

Kanchan, R. K., Perumal, N., Atri, P., Chirravuri Venkata, R., Thapa, I., Klinkebiel, D. L., Donson, A. M., Perry, D., Punsoni, M., Talmon, G. A., Coulter, D. W., Boue’, D. R., Snuderl, M., Nasser, M. W., Batra, S. K., Vibhakar, R. & Mahapatra, S., Jan 1 2020, (Accepted/In press) In : Brain Pathology.

Research output: Contribution to journalArticle

miR-15a-5p, miR-15b-5p, and miR-16-5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

Chava, S., Reynolds, C. P., Pathania, A. S., Gorantla, S., Poluektova, L. Y., Coulter, D. W., Gupta, S. C., Pandey, M. K. & Challagundla, K. B., Jan 1 2020, In : Molecular Oncology. 14, 1, p. 180-196 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

MnTnBuOE-2-PyP treatment protects from radioactive iodine (I-131) treatment-related side effects in thyroid cancer

Patel, A., Kosmacek, E. A., Fisher, K. W., Goldner, W. & Oberley-Deegan, R. E., Mar 1 2020, In : Radiation and Environmental Biophysics. 59, 1, p. 99-109 11 p.

Research output: Contribution to journalArticle

Open Access

Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance

Pothuraju, R., Rachagani, S., Krishn, S. R., Chaudhary, S., Nimmakayala, R. K., Siddiqui, J. A., Ganguly, K., Lakshmanan, I., Cox, J. L., Mallya, K., Kaur, S. & Batra, S. K., Feb 25 2020, In : Molecular cancer. 19, 1, 37.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

MUC16 as a potential target for the surgical detection of pancreatic cancer

Olson, M. T., Wojtynek, N. E., Caffrey, T. C., Radhakrishnan, P., Ly, Q. P., Talmon, G. A., Hollingsworth, M. A. & Mohs, A. M., Jan 1 2020, Molecular-Guided Surgery: Molecules, Devices, and Applications VI. Gioux, S., Gibbs, S. L. & Pogue, B. W. (eds.). SPIE, 112220M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11222).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

MUC1 oncoprotein mitigates ER stress via CDA-mediated reprogramming of pyrimidine metabolism

Olou, A. A., King, R. J., Yu, F. & Singh, P. K., Apr 16 2020, In : Oncogene. 39, 16, p. 3381-3395 15 p.

Research output: Contribution to journalArticle

MUCIN-4 (MUC4) is a novel tumor antigen in pancreatic cancer immunotherapy

Gautam, S. K., Kumar, S., Dam, V., Ghersi, D., Jain, M. & Batra, S. K., Feb 2020, In : Seminars in Immunology. 47, 101391.

Research output: Contribution to journalReview article

Nanoformulated SOD1 ameliorates the combined NASH and alcoholassociated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver

Gopal, T., Kumar, N., Perriotte-Olson, C., Casey, C. A., Donohue, T. M., Harris, E. N., Talmon, G., Kabanov, A. V. & Saraswathi, V., Jan 1 2020, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 318, 3, p. G428-G438

Research output: Contribution to journalArticle

Neuropilin-2 is an independent prognostic factor for shorter cancer-specific survival in patients with acinar adenocarcinoma of the prostate

Borkowetz, A., Froehner, M., Rauner, M., Conrad, S., Erdmann, K., Mayr, T., Datta, K., Hofbauer, L. C., Baretton, G. B., Wirth, M., Fuessel, S., Toma, M. & Muders, M. H., May 1 2020, In : International Journal of Cancer. 146, 9, p. 2619-2627 9 p.

Research output: Contribution to journalArticle

Open Access

Neutrophils are mediators of metastatic prostate cancer progression in bone

Costanzo-Garvey, D. L., Keeley, T., Case, A. J., Watson, G. F., Alsamraae, M., Yu, Y., Su, K., Heim, C. E., Kielian, T., Morrissey, C., Frieling, J. S. & Cook, L. M., Jun 1 2020, In : Cancer Immunology, Immunotherapy. 69, 6, p. 1113-1130 18 p.

Research output: Contribution to journalArticle

Open Access

Neutrophils in the Tumor Microenvironment

Wu, L., Saxena, S. & Singh, R. K., Jan 1 2020, Advances in Experimental Medicine and Biology. Springer, p. 1-20 20 p. (Advances in Experimental Medicine and Biology; vol. 1224).

Research output: Chapter in Book/Report/Conference proceedingChapter